Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
01/1999
01/05/1999US5856466 Coupling 2'-o-alkylated guanosine 3'-o-phosphoramidite with a 5'-hydroxyl moiety on an oligonucleotide
01/05/1999US5856465 Compositions and methods for the synthesis of chirally pure organophosphorus nucleoside derivatives
12/1998
12/30/1998WO1998058942A1 Non-sulfonated cyanine dyes for labeling nucleosides and nucleotides
12/30/1998EP0886641A2 Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
12/30/1998EP0766688A4 Synthesis of oligonucleotides
12/30/1998EP0737201A4 Backbone modified oligonucleotide analogs and solid phase synthesis thereof
12/30/1998EP0571474B1 Orthomolecular method of treating sickle cell disease
12/30/1998CN1203232A 2-carboxymethyl-5-(5-fluoro cyti midine-1-yl) 1,3-oxythiapentane and its derivatives
12/30/1998CA2294979A1 Non-sulfonated cyanine dyes for labeling nucleosides and nucleotides
12/29/1998US5853984 Use of nucleic acid ligands in flow cytometry
12/29/1998CA2035038C Synthetic intermediates of 2-alkynyladenosines, processes for preparing the synthetic intermediates, processes for preparing 2-alkynyladenosines utilizing the synthetic intermediates, and stable 2-alkynyladenosine derivatives
12/23/1998EP0885235A1 Nucleoside analogues
12/23/1998EP0885233A1 Terpyridine-platinum(ii) complexes
12/23/1998EP0642526B1 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose
12/23/1998CN1202493A Intermediate of doramectin for antiparastic chemical and its preparing method
12/22/1998US5852198 Wittig reagents and method for preparing α,β-unsaturated phosphonates
12/22/1998US5852188 Oligonucleotides having chiral phosphorus linkages
12/22/1998US5852182 Thiol-derivatized oligonucleosides
12/22/1998US5852027 Antiviral 1,3-dioxolane nucleoside analogues
12/22/1998US5851765 DNA sequencing by mass spectrometry via exonuclease degradation
12/17/1998WO1998056803A1 Novel optically active nucleoside derivative, its manufacturing method and anti-hbv agent containing the derivative thereof
12/17/1998WO1998056761A2 Benzimidazole derivatives
12/15/1998US5849906 Antigenic conjugates of polycyclic aromatic hydrocarbons to nucleosides
12/15/1998US5849905 Biologically active phosphotriester-type nucleosides and methods for preparing same
12/15/1998US5849890 High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
12/15/1998US5849479 High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
12/15/1998CA1340204C Microbiological process for making uk-61,689 and microorganisms useful therefor
12/10/1998WO1998055494A1 Treatmemt and prophylaxis of infarction by dinucleotides
12/10/1998WO1998055493A1 Natural antitumor or antiviral substances and use of the same
12/09/1998EP0882734A2 5'-Deoxy-cytidine derivatives
12/09/1998EP0882059A1 Solid phase synthesis of oligonucleotide n3-'p5'- phosphoramidates
12/09/1998EP0882058A1 Novel nucleoside derivatives and process for preparing the same
12/09/1998EP0745089B1 Antiparasitic agents
12/09/1998EP0541693B1 Large comb-type branched polynucleotides
12/09/1998CN1201463A Novel nucleoside derivatives and process for preparing same
12/09/1998CN1201037A 5'-deoxy-cytidine derivatives
12/08/1998US5847162 4, 7-Dichlororhodamine dyes
12/08/1998US5847117 Reagent and catalytic process useful for cleaving a protected functional group
12/08/1998US5847106 Monomeric and dimeric nucleosides with silyl-containing diamino phosphorous linkages
12/08/1998US5846728 Oligonucleotide-polyamide conjugates
12/08/1998US5846713 High affinity HKGF nucleic acid ligands and inhibitors
12/02/1998EP0880598A1 Nucleic acid analysis techniques
12/02/1998EP0880539A1 Nucleoside analogues
12/02/1998EP0528870B1 Protein-nucleic acid probes and immunoassays using same
12/01/1998US5844106 Modified oligonucleotides, their preparation and their use
12/01/1998US5843917 5-Fluorouracil derivatives
12/01/1998US5843912 Ring-expanded nucleosides and nucleotides
12/01/1998US5843653 Method for detecting a target molecule in a sample using a nucleic acid ligand
11/1998
11/26/1998WO1998052960A1 Process for the preparation of a deoxyuridine derivative
11/26/1998WO1998052606A1 Use of a cd40:cd154 binding interruptor to prevent counter adaptive immune responses, particularly graft rejection
11/26/1998CA2291156A1 Use of a cd40:cd154 binding interruptor to prevent counter adaptive immune responses, particularly graft rejection
11/25/1998EP0879056A1 MODULATION OF TH1/TH2 CYTOKINE EXPRESSION BY RIBAVIRIN$m(3) AND RIBAVIRIN$m(3) ANALOGS IN ACTIVATED T-LYMPHOCYTES
11/25/1998EP0842181A4 Membrane-permeant second messengers
11/25/1998EP0620004B1 Medicinal composition
11/24/1998US5840999 Asymmetric benzoxanthene dyes
11/24/1998US5840879 Dna or rna with labels
11/24/1998US5840876 2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic acids
11/24/1998US5840743 Modified benzimidazole nucleosides as antiviral agents
11/24/1998US5840674 Delivering active materials to mammalian cells
11/24/1998CA2139419C Purified saccharose synthase, process for its production and its use
11/18/1998EP0877751A1 Linker arm for solid support oligonucleotide synthesis and process for production thereof
11/17/1998US5837871 Nucleoside analogs
11/17/1998US5837861 Respiratory system disorders, bronchitis and cystic fibrosis
11/17/1998US5837859 Copolymer and nucleotides or hybrids
11/17/1998US5837835 Oligonucleotide N3'-P5' phosphoramidates: hybridization and nuclease resistance properties
11/17/1998US5837834 High affinity HKGF nucleic acid ligands and inhibitors
11/17/1998US5837456 Partitioning a nucleic acid, amplification of hormones
11/17/1998US5837279 Encapsulation of ionizable agents in liposomes
11/17/1998CA2142673C Aluminum/iron chelating compositions
11/12/1998WO1998030992A3 Fluorescent cyanine dyes
11/12/1998CA2289001A1 Novel heterocyclic compounds
11/11/1998EP0876390A1 Reusable solid support for oligonucleotide synthesis, process for production thereof and process for use thereof
11/11/1998EP0876389A1 Therapeutic compounds
11/11/1998EP0876380A1 $i(IN SITU) PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND OLIGONUCLEOTIDE SYNTHESIS
11/11/1998EP0876149A1 Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase
11/11/1998EP0597915B1 A process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
11/10/1998US5834607 For enhanced cellular uptake of oligonucleotides; antisense therapy
11/10/1998US5834436 Membrane-permeant second messengers
11/10/1998US5834266 Regulated apoptosis
11/10/1998CA2145682C 2-substituted adenosines with a-2 receptor affinity
11/05/1998WO1998049183A1 Base protecting groups and process for oligonucleotide synthesis
11/05/1998WO1998049178A1 Method of synthesis of 2´-o-substituted pyrimidine nucleosides and oligonucleotides
11/05/1998WO1998049177A1 Anti-viral pyrimidine nucleoside analogues
11/05/1998WO1998048849A1 Radionuclide associated with nucleotide polyphosphate as tumor imaging agents
11/04/1998EP0874848A1 Pyrimidine derivatives and guanine derivatives, and their use in treating tumour cells
11/04/1998EP0832286A4 Modified nucleotides for nucleic acid labeling
11/04/1998EP0828749A4 Compositions and methods for the synthesis of organophosphorus derivatives
11/03/1998US5831073 Ion triggered alkylation of biological targets by silyloxy aromatic agents
11/03/1998US5831072 Inhibitor of deaminase
11/03/1998US5831046 Boronic acid-contaning nucleic acid monomers
11/03/1998US5831045 Boronic acid-containing polynucleotides
11/03/1998US5830881 L-2'3',dideoxy nucleoside analogs as anti-hepatitus B (HBV) agents
11/03/1998US5830875 24-and 25-substituted avermectin and milbemycin derivatives
11/03/1998US5830717 Process for production of tricyclo compounds with streptomyces
11/03/1998US5830653 Methods of using oligomers containing modified pyrimidines
11/03/1998US5830645 Detection of amplification of cmyc oncogenes
11/03/1998US5830462 Regulated transcription of targeted genes and other biological events
10/1998
10/29/1998WO1998047910A1 Method for solution phase synthesis of oligonucleotides
10/29/1998CA2286320A1 Method for solution phase synthesis of oligonucleotides
10/27/1998US5827846 Carbazole derivatives as agents against multi-drug resistance