Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
12/2000
12/07/2000WO2000049032B1 Oligonucleotides having alkylphosphonate linkages and methods for their preparation
12/06/2000EP1057831A2 Process for the preparation of vinyl pyrimidine derivatives
12/06/2000EP1056759A1 2-(purin-9-yl) -tetrahydrofuran-3, 4-diol derivatives
12/06/2000CN1275983A Nucleosides analogues, such as antivirals including inhibitors of retroviral reverse transcriptase and the DNA polymerase of hepatitis B virus (HBV)
12/06/2000CN1275575A Process for synthesizing nucleotide and the like
12/06/2000CN1275566A Process for preparation of vinyl pyrimidine derivant
12/06/2000CN1059213C Preparation of d4T from 5-methyluridine
12/05/2000US6156889 Reagent useful for cleaving a protected functional group
12/05/2000US6156737 Therapy for hepatitis b
11/2000
11/30/2000WO2000071558A1 Orally active a1 adenosine receptor agonists
11/30/2000WO2000040605A3 Compositions and methods relating to cyclic compounds that undergo nucleotide base pair-specific interactions with double-stranded nucleic acids
11/30/2000WO2000039138A8 Selective solvent extraction for the purification of protected nucleosides
11/29/2000EP1054891A1 Prodrugs
11/29/2000EP0866796B1 Improvements in or relating to mutagenesis of nucleic acids
11/29/2000CN1058993C Prepn. and use of molecular chimera for treatment of cancer
11/28/2000US6153751 Preparing the antiviral b-isomer of a 1,3-oxathiolane nucleoside by reacting in presence of stannic chloride
11/28/2000US6153745 Relating to mutagenesis of nucleic acids
11/28/2000US6153744 Nucleoside derivatives with photolabile protective groups
11/28/2000US6153737 Derivatized oligonucleotides having improved uptake and other properties
11/28/2000US6153594 5'-O-acylated antiviral nucleosides
11/28/2000CA2121365C Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose
11/23/2000WO2000069877A1 4'-c-ethynyl purine nucleosides
11/23/2000WO2000069876A1 4'-c-ethynyl pyrimidine nucleosides
11/23/2000WO2000031100A3 Benzylmaltosides as inhibitors of smooth muscle cell proliferation
11/23/2000WO2000029420A3 Methods of making modified nucleosides
11/23/2000DE19923168A1 Neue Fluoreszenzfarbstoffe und ihre Verwendung als Fluoreszenzmarker New fluorescent dyes and their use as fluorescent markers
11/22/2000EP1054039A1 Fluorescent dyes and their use as fluorescent labelling agents
11/22/2000EP0721511B1 Method of preparing arabinonucleotides
11/22/2000CN1274361A Solution phase synthesis of oligonucleotides
11/22/2000CN1058723C D4T polymorphic form I process
11/21/2000US6150510 Modified oligonucleotides, their preparation and their use
11/21/2000US6150337 Ribavirin is used to suppress type 2-mediated t cell responses and promote type 1-mediated t cell response
11/16/2000WO2000068241A1 Processes for the synthesis of oligomers using phusphoramidite compositions
11/16/2000WO2000067698A2 Method for controlling the fidelity and execution of reverse transcriptase by incorporating and polymerising nucleotide analogues acceptable as substrates without blocking its elongation
11/16/2000CA2373672A1 Method for controlling the fidelity and execution of reverse transcriptase by incorporating and polymerising nucleotide analogues acceptable as substrates without blocking its elongation
11/15/2000EP1052265A1 Process for producing nucleoside derivatives
11/15/2000EP1052264A2 Process for the synthesis of nucleoside analogs
11/15/2000EP1051425A2 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES
11/15/2000EP1051424A1 Novel synthons for oligonucleotide synthesis
11/15/2000EP0650371B1 Covalent polar lipid-peptide conjugates for biological targeting
11/14/2000US6147211 Method for treating cyclic phosphate compound
11/14/2000US6147205 Arylalkyloxycarbonyl groups; for solid phase synthesis of oligonucleotides and polypeptides
11/14/2000US6147204 Complex for targeting therapeutic or diagnostic agents to preferential biological target
11/14/2000US6147200 2'-O-acetamido modified monomers and oligomers
11/14/2000US6147199 Viricides
11/14/2000US6147058 Antitumor agents
11/14/2000US6146886 RNA polymerase III-based expression of therapeutic RNAs
11/14/2000US6146829 Gapped 2' modified oligonucleotides
11/14/2000CA2105912C Nadh and nadph as drugs for treating alzheimer's disease
11/14/2000CA2103458C Method and composition to reduce myocardial reperfusion injury
11/11/2000CA2307951A1 Process for the synthesis of nucleoside analogs
11/09/2000WO2000066607A1 Detection using degradation of a tagged sequence
11/09/2000WO2000066604A2 L-ribo-lna analogues
11/09/2000WO2000066259A1 Method and apparatus for combinatorial chemistry
11/09/2000CA2368581A1 Detection using degradation of a tagged sequence
11/08/2000EP1049796A1 Methods for the simultaneous identification of novel biological targets and lead structures for drug development
11/08/2000EP1049744A1 Asymmetric cyanine dye quenchers
11/08/2000EP1049375A1 Method and compositions for promotion of wound healing
11/07/2000US6143882 Reacting a nucleoside starting material containing a leaving group with a vinylstanne of defined formula and carbon monoxide in presence of a palladium catalyst to form an ene-one intermediate, reacting with an amine, and isolating
11/07/2000US6143879 Nucleotide cleaving agents and method
11/07/2000US6143748 Multistage process with deetherification and reaction with nitrogen
11/07/2000US6143724 Used for treatment, improvement and prevention of inflammation and diseases accompanying inflamation
11/07/2000US6143497 Synthesizing random oligomers on particles using identification tags to facilitate identification of sequence of monomers
11/07/2000US6143279 Uridine 5'-diphosphate and analogs useful for treating lung diseases
11/02/2000WO2000064918A1 METHOD FOR THE PRODUCTION OF 2-CHLORO-2'-DEOXYADENOSINE (CLADRIBINE) AND ITS 3,5-DI-O-p-TOLUOYL DERIVATIVE
11/02/2000WO2000064484A2 Conjugate having a cleavable linkage for use in a liposome
11/02/2000WO2000040584A3 Process for preparing n6-substituted deaza-adenosine derivatives
11/02/2000WO2000039143A3 Antiviral nucleoside analogues
11/02/2000EP1047705A2 Nucleobase oligomers
11/02/2000EP1047704A2 Method for producing fludarabin phosphate lithium, sodium, potassium, calcium and magnesium salts, purification method for producing fludarabin phosphate and fludarabin phosphate which is at least 99.5 % pure
11/01/2000CN1272113A Lyxofuranosyl benzimidazoles as antiviral agents
11/01/2000CN1058011C 13-substituted milbemycin derivatives, and their use
10/2000
10/31/2000US6140495 Chemiluminescent 1,2-dioxetanes
10/31/2000US6140493 Method of synthesizing diverse collections of oligomers
10/31/2000US6140482 Primary phosphoramidate internucleoside linkages and oligonucleotides containing the same
10/31/2000US6140310 Phosphorous prodrugs
10/31/2000US6140120 Regulated transcription of targeted genes and other biological events
10/31/2000US6140051 Fluorescent dibenzazole derivatives and methods related thereto
10/31/2000CA2175451C Isolated components of dense microspheres derived from mammalian brain tissue and antibodies thereto
10/26/2000WO2000062803A2 ppGpp AND pppGpp AS IMMUNOMODULATORY AGENTS
10/26/2000WO2000020428A9 Synthesis of oligosaccharides, reagents and methods related thereto
10/25/2000EP1046648A1 3'-deoxyribonucleotide derivatives
10/25/2000EP1046421A2 Methods and reagents for very large scale immobilized polymer synthesis
10/25/2000EP1045897A1 Enzyme catalyzed therapeutic agents
10/25/2000EP1045636A1 Pharmaceutical compositions and methods for the treatment of failing myocardial tissue
10/24/2000US6136961 Biocatalytic methods for synthesizing and identifying biologically active compounds
10/24/2000US6136791 Viricides and anticarcinogenic agents
10/24/2000CA2139664C Covalent polar lipid-peptide conjugates for biological targeting
10/24/2000CA2124814C 2'-deoxy-isoquanosines, isosteric analogues and isoquanosine derivatives as well as their use
10/19/2000WO2000061816A1 Electronically mediated nucleic acid amplification in nasba
10/19/2000WO2000061783A2 Process for preparing inhibitors of nucleoside metabolism
10/19/2000WO2000061594A2 Nucleoside derivatives with photo-unstable protective groups
10/19/2000WO2000061565A1 Propynyl uracils
10/19/2000DE19915867A1 New nucleoside derivatives with photolabile protecting groups, useful in oligonucleotide synthesis, particularly on solid phases, e.g. for hybridization testing
10/19/2000CA2696826A1 Process for preparing inhibitors of nucleoside metabolism
10/19/2000CA2368458A1 Propynyl uracils
10/19/2000CA2365996A1 Electronically mediated nucleic acid amplification in nasba
10/18/2000EP1044987A2 Gapped 2'-modified oligonucleotides
10/18/2000EP1044004A1 A2a adenosine receptor agonists in combination with a type iv phosphodiesterase inhibitors
10/18/2000EP0603251B1 1-substituted 1h-imidazo(4,5-c)quinolin-4-amines; intermediate and pharmaceutical compositions