Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
03/2001
03/28/2001EP1086065A1 Combinatorial synthesis of multibinding libraries
03/28/2001EP1086064A2 Directed combinatorial compound library and high throughput assays for screening same
03/28/2001EP1085893A1 Phosphodiesterase-v modulator drugs and their uses
03/28/2001EP1085891A1 Multibinding inhibitors of topoisomerase
03/28/2001EP1085861A1 Inhibitors of nitric oxide synthase
03/28/2001EP1085846A2 Multibinding inhibitors of microsomal triglyceride transferase protein
03/28/2001EP1085845A2 Multibinding inhibitors of cyclooxygenase-2
03/28/2001CN1289338A 2-(purin-9-yl)-tetahydrofuran-3,4-diol derivatives
03/27/2001US6207819 Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds
03/27/2001US6207650 Antiviral, highly water soluble, stable, crystalline salts of 2′, 3′-dideoxyinosine, 2′, 3′-dideoxy-2′, 3′-didehydrothymidine and 2′, 3′-dideoxy-2′-fluoroinosine
03/27/2001US6207649 Nucleoside analogs and uses in treating disease
03/22/2001WO2001020040A2 Method and compositions for evaluating resolution of nucleic acid separation systems
03/22/2001WO2001020035A2 Methods and compositions for linear isothermal amplification of polynucleotide sequences
03/22/2001DE19951715C1 New 18-fluoro-labeled cytosine derivatives, useful as tracers for monitoring activity of transferred cytosine deaminase genes in gene therapy of tumors
03/21/2001EP1083920A1 Novel antibacterial compounds
03/21/2001EP1083919A1 Novel antiviral compounds
03/21/2001EP1083894A1 MULTIBINDING INHIBITORS OF HMG-CoA REDUCTASE
03/21/2001EP0979233A4 Method for solution phase synthesis of oligonucleotides
03/21/2001CN1063445C Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds
03/21/2001CN1063322C Aqueous liquid composition for eye external use as eyedrops
03/20/2001US6204249 For the treatment or prophylaxis of virus infections such as those caused by herpes viruses.
03/15/2001WO2001018015A1 Oligonucleotide n3'→p5' thiophosphoramidates: their synthesis and use
03/15/2001WO2000078779A3 N-pyrazole a2a receptor agonists
03/14/2001EP1082012A1 Novel nucleosides having bicyclic sugar moiety
03/14/2001CN1063183C Heterocyclic radical, saccharous radical polysubstituted pyrrodiazoles compound and synthetic method thereof
03/13/2001US6201752 Timing circuit for high voltage testing
03/13/2001US6201005 Method for inhibiting lymphokine production
03/13/2001CA2226363C D-pentofuranose derivatives and process for preparing the same
03/13/2001CA2082528C Antitumor substance be-13793c derivatives
03/08/2001WO2001016369A2 Uv excitable fluorescent energy transfer dyes
03/08/2001WO2001016365A1 Poly(ether-thioether), poly(ether-sulfoxide) and poly(ether-sulfone) nucleic acids
03/08/2001WO2001016312A2 Nucleic acid based modulators of gene expression
03/08/2001WO2001016151A1 Reversible photocoupling nucleic acid and phosphoroamidite
03/08/2001WO2001016150A2 Nucleoside analogues
03/08/2001WO2001016149A2 2-azapurine compounds and their use
03/08/2001WO1999064047A8 Novel antiviral compounds
03/08/2001CA2403243A1 Nucleic acid based modulators of gene expression
03/08/2001CA2382663A1 Uv excitable fluorescent energy transfer dyes
03/08/2001CA2382324A1 Nucleoside analogues
03/07/2001EP1081155A2 N6 heterocyclic substituted adenosine derivatives
03/07/2001EP1080726A1 Agents for relieving side effects
03/07/2001EP0915935B1 4,7-dichlororhodamine dyes
03/07/2001CN1286632A Use of purine nucleosides for modulating axonal outgrowth of central nervous system neurons
03/07/2001CN1286258A Purine L-nucleoside, analogs and use thereof
03/06/2001US6197949 Supports and novel processes for binding oligonucleotides
03/06/2001US6197944 DNA molecules stabilized by modifications of the 3′-terminal phosphodiester linkage
03/06/2001US6197555 Nucleotide compounds including a rigid linker
03/06/2001US6197506 Using substrate having over 100 different polynucleotides at density of over 50 different polynucleotides per square centimeter to generate hybridization patterns and distinguish between two nucleic acid samples; heredity; diagnosis
03/01/2001WO2001014401A1 Nucleoside pyrophosphate and triphosphate analogs and related compounds as therapeutic agents
03/01/2001WO2001014400A1 2'-o-acetamido modified monomers and oligomers
03/01/2001WO2001014399A1 Novel a-500359 derivatives
03/01/2001WO2001014345A1 5-propynylpyrimidine derivatives as cytotoxic enzyme inhibitors
03/01/2001WO2000066607A8 Detection using degradation of a tagged sequence
03/01/2001CA2382467A1 Nucleoside pyrophosphate and triphosphate analogs and related compounds as therapeutic agents
02/2001
02/28/2001CN1285844A Compound
02/28/2001CN1285843A Compound
02/28/2001CN1285842A Compound
02/27/2001USRE37077 Adenosine derivatives and pharmaceutical composition thereof
02/27/2001US6194598 Aminooxy-modified oligonucleotide synthetic intermediates
02/27/2001US6194576 Coupling purine or pyrimidine base with nucleotide analog phosphonate compound
02/27/2001US6194393 A glycoside containing an anomeric sulfoxide and nucleophilic functional groups and having potential glycosyl accepting/donating characteristics and an activating agent; rapid construction oligosaccharides; glycosylation; library
02/27/2001US6194150 Nucleic acid based inhibition of CD40
02/27/2001CA2191230C 2-halo-2'-deoxyadenosine treatment for inflammatory bowel disease
02/27/2001CA2110582C Modified sialyl lewis a compounds
02/22/2001WO2001012644A1 Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptases and viruses
02/22/2001WO2001012643A1 Antibiotic caprazamycins and process for producing the same
02/22/2001WO2001012642A2 Nucleoside derivatives and a method for producing same
02/22/2001DE19938092A1 Nucleosidderivate und Verfahren zu deren Herstellung Nucleoside derivatives and methods for their preparation
02/21/2001CN1285003A Screening appays for the detection and diagnosis of influenza virus
02/21/2001CN1285001A Methods for simultaneous identification of novel biological targets and lead structures for drug development
02/21/2001CN1284880A Hyperhydrated citicoline, process and use
02/20/2001US6191278 Water-soluble rhodamine dyes and conjugates thereof
02/20/2001US6191266 Sugar modified nucleosides
02/20/2001US6191120 Spermicidally active 5-halo-6-alkoxy-5,6-dihydro-2′,3′-dideoxy-uridines and their pharamaceutical compositions
02/20/2001US6190869 Antisense inhibition of protein kinase C-theta expression
02/20/2001CA2110797C Modified sialyl lewis x compounds
02/15/2001WO2001010882A1 Depot forms of modified nucleoside 5'-hydrogenphosphates as inhibitors of reproduction of human immunodeficiency virus and human hepatitis b virus
02/13/2001US6187914 Solid phase synthesis of oligonucleotides using electrochemically labile protecting groups which can be removed by creating potential difference between working electrode and counterelectrode
02/13/2001US6187913 Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method
02/13/2001US6187587 Nucleotide sequences; for diagnosis and treatment of related disorders
02/13/2001US6187568 Culture product of actinoplane; immunosuppressant, fungicides, antitumor agents
02/13/2001US6187286 Tumor imaging agents, methods and kits
02/13/2001CA2012046C Use of 5'-deoxy-5'-methylthioadenosine, s-adenosylmethionine and their salts for reducing seborrhea
02/13/2001CA2012045C Pharmaceutical compositions containing 5'-deoxy-5'- methylthioadenosine, s-adenosylmethionine and their salts for hair growth in subjects suffering baldness
02/08/2001WO2001009390A1 Tenascin-c nucleic acid ligands
02/08/2001WO2001009156A1 HIGH AFFINITY TGFη NUCLEIC ACID LIGANDS AND INHIBITORS
02/08/2001WO2000061783A3 Process for preparing inhibitors of nucleoside metabolism
02/08/2001WO2000057180A3 Use of lna in mass spectrometry
02/08/2001CA2380837A1 High affinity tgf.beta. nucleic acid ligands and inhibitors
02/08/2001CA2380473A1 Tenascin-c nucleic acid ligands
02/07/2001EP1073732A2 Nucleoside triphosphates and their incorporation into ribozymes
02/07/2001EP0562025B1 Compounds and their use in a binary synthesis strategy
02/07/2001CN1283234A Method for suppressing multiple drug resistant in cancer cells
02/06/2001USRE37045 N-6 substituted-5′-(N-substituted carboxamide)adenosines as cardiac vasodilator and antihypertensive agents
02/06/2001US6184364 Dehydrating uridine to form 2,2'-anhydrouridine, converting to unprotected 2'-azido-2'-deoxyuridine, iodinating to form 5-iodo-2'-azido, 2'-deoxyuridine, then reducing to 5-iodo, 2'-amino-2'-deoxyuridine; selex ligands
02/06/2001US6184347 Selecting and applying a reactive wash solution that is not reactive to growing polymer but deactives unused reactive agents and is miscible with reaction solution; removes reaction solution from surface of solid phase
02/01/2001WO2001007455A1 Novel bicyclonucleoside analogues
02/01/2001WO2001007454A1 Enzyme catalyzed therapeutic activation
02/01/2001WO2001007088A2 Methods for treating therapy-resistant tumors
02/01/2001WO2001007087A2 Enzyme catalyzed anti-infective therapeutic agents