| Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574) |
|---|
| 05/04/2004 | US6730497 Enzymatically converting a 3-thiolated cephalosporin c into a 3-thiolated-alpha-ketoadipyl-7-aminocephalosporanic acid derivative of use in the preparation of cephalosporin c antibiotics and derivatives thereof |
| 04/29/2004 | WO2004035800A2 Intermediate cefdinir salts |
| 04/29/2004 | WO2004035593A1 An improved process for the preparation of cefadroxil |
| 04/29/2004 | US20040082560 Cephalosporin antibiotic against gramnegative bacteria; dissolving in water immiscible solvent; hydrolysis, acidification; good color, solubility |
| 04/29/2004 | CA2500791A1 Intermediate cefdinir salts |
| 04/28/2004 | CN1492867A Novel thioes derivatives of thiazolyl acetic acid and their use in preparation of cephalosporin compounds |
| 04/27/2004 | US6727243 Solid solution dissolved in a polymer |
| 04/27/2004 | US6726911 Biologically active compounds of Ganoderma pfeifferi DSM 13239 |
| 04/22/2004 | WO2004033464A1 Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4- carboxylic acid |
| 04/22/2004 | US20040077850 For treating human/animal gram-positive/negative bacteria infections |
| 04/22/2004 | US20040077849 For improved yield |
| 04/21/2004 | EP1409492A1 An improved method for preparation of cefuroxime axetil |
| 04/21/2004 | EP0941095B1 Improved pharmaceutical compositions |
| 04/20/2004 | US6723716 7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof |
| 04/15/2004 | US20040073023 Clathrate of cephalosporin with dimethylforamide; isolation, purification |
| 04/14/2004 | CN1145629C Synthesis of cynnematin |
| 04/14/2004 | CN1145628C Synthesis of cynnematin |
| 04/08/2004 | WO2003093278A3 Process for the preparation of ceftiofur acid |
| 04/08/2004 | US20040067549 A process for the preparation of 3-thiolated derivatives of 3-acetoxy-methyl-7-amino-ceph-3-em-carboxylic acid; antibiotics |
| 04/07/2004 | EP1405922A2 Substrates for beta-lactamase and uses thereof |
| 04/07/2004 | EP0968214B1 Purification process |
| 04/01/2004 | WO2004026882A1 Process for the preparation of cephems |
| 03/31/2004 | EP0796262B1 7-alkylidene cephalosporanic acid derivatives and methods of using the same |
| 03/30/2004 | US6713625 Process for the preparation of cefditoren using the thioester of thiazolylacetic acid |
| 03/24/2004 | EP1399429A1 1,3,4-oxadiazol-2-yl thioesters and their use for acylating 7-aminocephalosporins |
| 03/24/2004 | CN1142938C Process for prepn. of sefpodoxime proxetil diastereoisomers |
| 03/24/2004 | CN1142937C Antibacterial cephalosporins |
| 03/17/2004 | EP0804441B1 Clavulanic acid extraction process |
| 03/10/2004 | EP1209160B1 Process for the preparation of cephem compounds |
| 03/03/2004 | EP1392704A1 Cephem compounds |
| 03/03/2004 | EP1392703A1 Crystalline acid salts of cefdinir and process for preparing cefdinir using same |
| 03/03/2004 | EP1220859B1 Process for preparing 7-amino-3-methoxymethyl-3-cephem-4-carboxylic acid |
| 02/26/2004 | WO2004016623A1 A cefdinir intermediate |
| 02/25/2004 | CN1478094A Process and ester derivatives for preparing cephalosporins |
| 02/25/2004 | CN1478093A Coupling process and intermediates useful for preparing cephalosphorins |
| 02/25/2004 | CN1139596C Crystalline amine salt of cefdinir |
| 02/19/2004 | US20040034236 Converting a protected 1,4- dihydroxy-2-amino or protected amino butane in presence of hydroxylamine or an acid additon salt into N-hydroxy-pyrrolidone derivative, reducting N-hydroxy group to secondary amine by hydrogenation |
| 02/18/2004 | EP1389187A2 Process for the preparation of cefpodoxime acid |
| 02/18/2004 | CN1138781C Process for recovery cephalosporin from fermentative liquid |
| 02/17/2004 | US6693095 7-(((5-amino-1,2,4-thiadiazol-3-yl)-(z)-(fluormethoxyimino) -acetyl)amino)-3(e)-((imino-1-piperazinylmethyl)-methylhydrazono)methyl-3 -cephem-4-carboxylic acid trihydrochloride for example |
| 02/12/2004 | WO2004013097A1 Process for the preparation of amino-pyrrolidine derivatives |
| 02/12/2004 | US20040030127 Process for the preparation of highly crystalline sodium cefoperazone |
| 02/11/2004 | CN1474823A Cephem compounds and ESBL detecting reagents containing same |
| 02/11/2004 | CN1473833A Cefradine crystal and method for preparing cefradine |
| 02/05/2004 | WO2004011471A1 Process for the preparation of cephem esters |
| 02/05/2004 | US20040023943 A cephem compound (particularly its crystal) represented by the formula (I), wherein X is CH3COOH, CH3CH2COOH or CH3CN, and n is 0 to 5, is useful as an antibacterial agent (particularly anti-MRSA agent) and shows superior quality such |
| 02/05/2004 | US20040023290 Novel therapeutic agents that modulate enzymatic processes |
| 02/04/2004 | EP1385853A2 Beta-lactamase substrates having phenolic ethers |
| 02/04/2004 | EP1268488A4 A process for preparing cephalosporin derivatives using new thiazole compound |
| 02/04/2004 | CN1136852C Pharmaceutical formulations of cefaclor |
| 01/29/2004 | US20040019202 Cephem compounds and esbl-detecting reagents containing the same |
| 01/28/2004 | CN1471399A Cephalosporin antibiotics and prodrugs thereof |
| 01/28/2004 | CN1136222C 3-(2-oxo[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems |
| 01/28/2004 | CN1136221C Process for preparing cephem compounds |
| 01/27/2004 | US6683176 Intermediates for and synthesis of 3-methylene cephams |
| 01/27/2004 | CA2069200C Crystalline acid addition salts of diastereomerically pure 1-(2,2-dimethylpropionyloxy)-ethyl-3-cephem-4-carboxylate |
| 01/22/2004 | WO2004007505A1 Cephalosporins |
| 01/22/2004 | CA2492373A1 Cephalosporins |
| 01/21/2004 | EP1382608A1 Sulfate of cephem compound |
| 01/21/2004 | EP1381690A2 Enzymatic process for preparing cephalosporin derivatives |
| 01/21/2004 | EP0948491B1 Aminothiazole derivatives useful in the preparation of beta-lactam antibiotics |
| 01/20/2004 | CA2089441C Process for the preparation of cephem prodrug esters |
| 01/14/2004 | EP1379531A2 Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives |
| 01/14/2004 | EP1379530A1 Process for the selective preparation of 3-(z) propenyl-cephem compound |
| 01/14/2004 | CN1134447C Cefixime tert-octyl ammonium salts , process for preparing the same and method for purification of cefixime |
| 01/14/2004 | CN1134446C Process for preparation of 3-vinylcephem compound |
| 01/06/2004 | CA2080573C Novel bioprocesses for preparing 7-aca and 7-adac |
| 01/02/2004 | EP1373276A1 Process for the preparation of cefpodoxime proxetil |
| 01/01/2004 | US20040002601 Method for producing cephalosporins |
| 01/01/2004 | US20040002600 Antibiotics |
| 12/31/2003 | WO2004000848A1 Process for the conversion of penam ring system to cepham ring system |
| 12/31/2003 | WO2004000323A1 Medicinal cephem compound composition for injection |
| 12/31/2003 | CN1132833C Vinyl-pyrrolidone cynnematin with alkali subtituent |
| 12/25/2003 | US20030236243 Sterically-awkward beta-lactamase inhibitors |
| 12/24/2003 | CN1462751A Method for preparing crystalline cefathiamidine and its usage |
| 12/17/2003 | EP1370296A2 Catecholate beta-lactam conjugates, method for producing the same and the use thereof |
| 12/17/2003 | CN1462275A Phosphonocephem compound |
| 12/04/2003 | WO2003099826A1 A new process for the preparation of cefditoren using the thioester of thiazolylacetic acid |
| 12/04/2003 | WO2003011871A3 Intermediates in cephalosporin production |
| 12/04/2003 | WO2002068678A3 Beta-lactamase substrates having phenolic ethers |
| 12/04/2003 | US20030225265 Process for the preparation of cefditoren using the thioester of thiazolylacetic acid |
| 12/03/2003 | EP1365764A1 Oral pharmaceutical composition of cefpodoxime proxetil |
| 12/03/2003 | CN1129596C Synthetic intermediate of cephalo olefine compound |
| 11/20/2003 | US20030216567 New method for the preparation of ceftiofur sodium and its intermediates |
| 11/20/2003 | US20030216372 Inhibitors of serine and metallo-beta-lactamases |
| 11/19/2003 | CN1128150C Process for the preparation of Beta-phdroxy esters |
| 11/13/2003 | WO2003093278A2 Process for the preparation of ceftiofur acid |
| 11/06/2003 | WO2003091261A1 Process for the preparation of cefdinir |
| 11/06/2003 | WO2003091230A1 Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate |
| 11/06/2003 | US20030208065 Reacting 7-amino-3-vinylceph-3-em-4-carboxylic acid with 2-(2-amino-4-thiazolyl-2(aryl or alkyl)oxycarbonylmethyoxy-iminoacetylthio-)benzothiazole to obtain Cefixime; salt formation with tert-octylamine; crystal structure |
| 11/06/2003 | CA2483482A1 Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate |
| 11/05/2003 | EP1359153A1 Beta-lactamase inhibiting compounds |
| 11/05/2003 | CN1454212A Intermediates in cephalosporing production |
| 11/05/2003 | CN1453280A Prepn of cefotaxime |
| 11/05/2003 | CN1126754C Process for preparing 3-cephem compound |
| 11/04/2003 | US6642378 Carbamoylation of the 3-hydroxymethyl derivative with chlorosulfonyl isocyanate |
| 11/04/2003 | US6642377 Process for the preparation of basic antibiotic-inorganic acid addition salts and intermediate oxalates |
| 11/04/2003 | US6642020 Process for preparing cephalosporin derivatives |
| 10/30/2003 | WO2003089406A1 A process for the preparation of cephalosporin intermediate and its use for the manufacture of cephalosporin compounds |
| 10/30/2003 | US20030204095 Reducing thiazole ester to thiazole alcohol using sodium borohydride in the presence of aluminum chloride in a solvent and oxidising the thiazole alcohol to obtain 4-methyl-5-formyl-thiazole |