| Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574) |
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| 11/18/2008 | US7452990 4-halo-2-oxyimino-3-oxo butyric acid-N,N-dimethyl formiminium chloride chlorosulfate; cephalosporins that may be prepared from the intermediate include cefdinir, cefditoren pivoxil, cefepime, cefetamet pivoxil, cefixime, cefmenoxime, cefodizime, cefoselis, cefotaxime, cefpirome, cefpodoxime proxetil, etc |
| 11/18/2008 | CA2331850C Method of preparing carboxylic acid derivatives and condensing agent comprising a quaternary ammonium salt |
| 11/18/2008 | CA2314564C Phosphonocephem derivatives, their production and use |
| 11/13/2008 | US20080281093 Reducing impurities; reacting 4-hydroxy-((3-methoxy-1-methyl-3-oxo-1-propenyl)aminobenzeneacetic acid, monopotassium salt with ethyl chloroformate; hydrosilation with N,O-bis(trimethylsilyl)acetamide; reacting with (7-trimethylsilylamino)-2 -propen-1-yl)cephen-4-carboxylic acidtrimethylsilyl ester |
| 11/12/2008 | CN101302226A Preparation of cephamycine intermediate compound |
| 11/06/2008 | WO2008132574A1 Purification of cefuroxime acid |
| 11/06/2008 | WO2007053724A3 Crystalline forms of cefdinir potassium salt |
| 11/05/2008 | EP1987041A1 Improved cephalosporin production |
| 10/30/2008 | WO2007105253A8 PREPARATION OF (1-OXA- OR l-THIA-)3- CEPHEM DERIVATIVES |
| 10/29/2008 | CN101293891A Method for preparing ceftazidime midbody |
| 10/23/2008 | US20080262219 Water solubility, stability, filterability , anhydrous crystals; crystallization in acidity solution |
| 10/22/2008 | EP1319009B1 Intermediates in cephalosporin production |
| 10/22/2008 | CN101289459A Cephalosporin derivatives with nitrogen-onium ion azazocyclo |
| 10/22/2008 | CN101289458A Refining process for crude product of ceftriaxone sodium |
| 10/22/2008 | CN101289457A Novel process for synthesizing 3-deacetyl cefuroxime sodium (DCCF) |
| 10/22/2008 | CN101289456A Method for synthesizing cefuroxime sodium |
| 10/22/2008 | CN101288841A Macroporous adsorption resin special for extracting cephalosporin C and its preparation method |
| 10/15/2008 | EP1409492B1 An improved method for preparation of cefuroxime axetil |
| 10/15/2008 | CN101284840A Synthetic method of cefpirome sulfate |
| 10/15/2008 | CN101284839A Method and device for preparing superfine amorphousn cefuroxime axetil |
| 10/09/2008 | WO2008002245A8 Imidazol-pyrimidine derivatives for treatment of diseases related to glycogen synthase kinase (gsk3) |
| 10/08/2008 | CN101279981A Refining method of cefbuperazone intermediate |
| 10/08/2008 | CN101279980A Separation and purification method of cefminox sodium and preparation of cefminox sodium freeze-dried powder injection |
| 10/08/2008 | CN101279979A Separation and purification method of cefamandole nafate and preparation of cefathiamidine freeze-dried injectable powder |
| 10/08/2008 | CN101279978A Separation and purification method of cefathiamidine and preparation of cefathiamidine power injection |
| 10/02/2008 | US20080242858 Reacting 7-amino-3-vinyl-3-cephem-4-carboxylic acid with 2-mercapto-1,3-benzothiazolyl-(Z)-2-(2-aminothiazol-4-yl)-2-(alkoxycarbonyl)-methoxyimino acetate and an amine base to form an amine salt of a cefixime ester, extracting with ethyl acetate or CH2Cl2, hydrolyzing, acidifying, and crystallizing |
| 10/01/2008 | CN101274937A Preparation for cefbuperazone sodium |
| 09/24/2008 | CN101270125A 7-amido-3-hydroxyl methyl-3-cephalosporin-4-carboxylic acid crystal and preparing method thereof |
| 09/23/2008 | US7427692 Process for preparation of 7-[α-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid |
| 09/23/2008 | US7427680 Fluorogenic substrates for BETA-lactamase gene expression |
| 09/17/2008 | CN100418972C Cephe alkene onium salt compound and its preparation and use in preparation of cefepime |
| 09/11/2008 | US20080221076 Crystalline Sodium Salt of Cephalosporin Antibiotic |
| 09/10/2008 | CN101260116A Method for synthesizing 7-phenylacetamide-3-chloromethyl-4-cephalosporanic acid p-methoxybenzyl ester |
| 09/02/2008 | US7419973 Phosphonocephem compound |
| 09/02/2008 | CA2379650C Process for producing a basic antibiotic inorganic acid salt, and oxalate intermediate |
| 08/28/2008 | US20080207912 Reacting2-( 2-aminothiazol-4-yl)-2-methyloxyimino acetic acid-2-benzothiazolyl thioester with 7-amino-3-(2-furocarbonylthiomethyl)-3-cephem-4-carboxylic acid |
| 08/27/2008 | CN100413506C Improved pharmaceutical compositions |
| 08/21/2008 | US20080200670 Industrial scale, low cost, one pot process; yield, purity, storage stability; low color absorbance; utilizing high purity 4-halo-2-methoxyimino-3-oxo butyric acid derivative reactant and acid scavenging agent |
| 08/20/2008 | CN101245081A Novel cephalosporin derivative |
| 08/20/2008 | CN101245080A Cephalosporin derivatives containing pyrazole triazole |
| 08/20/2008 | CN101245079A Cephalosporin antibiotic derivant |
| 08/20/2008 | CN101245078A Benzathine salt of ceftiofur, preparation method and application thereof |
| 08/20/2008 | CN101245077A Novel cephalosporin derivatives |
| 08/19/2008 | CA2219656C Antibacterial cephalosporins |
| 08/14/2008 | US20080194465 Cross-linked glycopeptide-cephalosporin antibiotics |
| 08/14/2008 | US20080194464 Chemical intermediate thereto; effective against antibiotic-resistant strains of bacteria, such as methicillin-resistant Staphylococci aureus (MRSA) |
| 08/13/2008 | CN101239985A Method for preparing cefodizime sodium |
| 08/06/2008 | CN101235045A Method for preparing cefoxitin sodium |
| 07/31/2008 | US20080182836 Cephalosporin compounds comprising a C3 thio-methyl moiety substituted with N-containing heterocyclic group, and a C7 thiourea acetamido group, their preparations and uses thereof |
| 07/30/2008 | EP1950215A1 Sodium cefazolin pentahydrate crystal and its assembly preparation method |
| 07/30/2008 | EP1028118B1 Process for producing 3-cephem compounds |
| 07/30/2008 | CN101230070A Novel anti-infection cephalosporin compounds |
| 07/30/2008 | CN101230069A Novel cephalosporin derivant |
| 07/30/2008 | CN101229129A Ceftezole sodium powder injection and synthesizing method thereof |
| 07/29/2008 | US7405294 7-[2-(aminothiazol-4-yl)-2-(trityloxyimino)-acetamido]-3-vinyl-3-cephem-4-carboxylic acid dicyclohexylamine salt;cephalosporins; broad antibacterial spectrum especially against staphylococci and streptococci |
| 07/29/2008 | CA2261835C Long-acting drugs and pharmaceutical compositions comprising them |
| 07/24/2008 | US20080177061 Target for therapy of cognitive impairment |
| 07/24/2008 | US20080176825 Oral Neurotherapeutic Cefazolin Compositons |
| 07/23/2008 | CN101225088A Method for preparing cephalosporin propylene |
| 07/17/2008 | WO2008056221A3 Crystalline sulfate salt of cephalosporin antibiotic |
| 07/16/2008 | EP1943256A2 Crystalline forms of cefdinir potassium salt |
| 07/16/2008 | CN101220042A Novel cephalosporin compound |
| 07/16/2008 | CN101220041A Cephalosporin derivant |
| 07/16/2008 | CN101220040A Preparation of cefixime cephalosporin and fine purification method |
| 07/10/2008 | US20080167270 Anti-infective phosphonate analogs |
| 07/08/2008 | US7396926 Compound for use in the measurement of gene expression |
| 07/02/2008 | CN101210023A Novel cephalosporin derivatives |
| 07/02/2008 | CN101210022A Cephalosporin |
| 07/02/2008 | CN101210021A Cephalosporin compounds |
| 07/02/2008 | CN101210020A Cephalosporin compound |
| 07/02/2008 | CN101210019A Methoxy cephalosporin intermediate |
| 07/02/2008 | CN100398547C Process for producing 3-chloromethyl-3-cephem derivative |
| 06/25/2008 | EP1934231A1 Crystalline sodium salt of cephalosporin antibiotic |
| 06/19/2008 | US20080146535 i.e. (7R)-7-[(Z)-2-(2-amino-5-chlorothiazol-4-yl)-2-(triphenylmethoxyimino]-acetamido]-3-chloro-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate triethyl amine salt; bacterial infections caused by methicillin-resistant Staphylococcus aureus and various genus Enterococcus bacteria |
| 06/18/2008 | CN101200473A Method for preparing cefepime dihydrochloride monohydrate crystal |
| 06/12/2008 | WO2008010042A3 Improved process for the preparation of cefepime intermediate |
| 06/11/2008 | EP1930335A1 Cephalosporines having cyclic aminoguanidine substituents as Antibiotics |
| 06/10/2008 | US7384928 7-side chain is substituted with aminothiazole and 3-position with a cyclic-type quarternary ammoniummethyl group; antibacterial activities against cephem-resistant Pseudomonas aeruginosa which produce beta -lactamase; antibiotic resistance; pharmacokinetics; high water solubility; injection |
| 06/10/2008 | CA2418614C Phosphonocephem compound |
| 06/04/2008 | CN101190922A Cephalosporin derivative |
| 06/04/2008 | CN101190921A Method for preparing p-nitrobenzyl-7-phenoxyacetamido-3-exomethylenecepham-4-carboxylate-1-beta-oxide |
| 06/04/2008 | CN100391961C Pentahydro cephalontzoline sodium crystal structure and process for assembly preparing crystal molecule |
| 06/03/2008 | CA2180829C Cephalosporin synthesis |
| 05/28/2008 | CN101186614A Preparation method for methoxyl benzyl ester |
| 05/21/2008 | CN101182327A Cefdinir |
| 05/21/2008 | CN101182326A Method for preparing 7-amido-3-vinyl cethalosporanic acid |
| 05/15/2008 | WO2008056221A2 Crystalline sulfate salt of cephalosporin antibiotic |
| 05/13/2008 | CA2324953C Cephalosporines having cyclic aminoguanidine substituents as antibiotics |
| 05/08/2008 | US20080108558 Cross-linked glycopeptide-cephalosporin antibiotics |
| 05/07/2008 | CN101172982A Method of preparing cefpirome sulfate |
| 05/01/2008 | US20080103299 Potency against gram-positive bacteria, methicillin-resistant Staphylococci aureus (MRSA), methicillin-resistant Staphylococci epidermitis (MRSE). |
| 04/30/2008 | CN100384857C Cephalosporin ester compound resisting beta-lactamase and its salt |
| 04/24/2008 | WO2008047376A1 An improved process for the preparation of cephalosporin antibiotic |
| 04/16/2008 | CN101161655A Method for synthesizing cefpirome sulfate |
| 04/16/2008 | CN100381445C Preparing process of cefetamet sodium |
| 04/10/2008 | WO2008041100A1 Improved process for the preparation of cephalosporin antibiotics |
| 04/09/2008 | CN101157698A Novel cephalosporin derivant |
| 04/09/2008 | CN101157697A Cefuroxime dibenzyl ethylenediamine salt and preparation method and application thereof |
| 04/08/2008 | US7355041 Intermediates in cefprozil production |
| 04/08/2008 | US7355040 Process for the preparation of cephalosporin compounds and synthetic intermediates |