Patents
Patents for C07D 501 - Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (7,574)
09/2004
09/22/2004CN1531598A Enzymatic process for preparing cephalosporanic acid derivatives
09/22/2004CN1531539A Enzymatic process for preparing cephalosporanic acid derivatives using 2-ketoacid derivatives
09/21/2004US6794372 Nitrate salts of antimicrobial agents
09/16/2004US20040181056 using an enzyme system that comprises co-immobilised D-Amino acid oxidase and catalase; chemical intermediates for Cephalosporin C and derivatives
09/15/2004EP1455900A1 Methods of treating bacterial infections in dogs and cats
09/15/2004EP1274695A4 New thiazol compounds and their preparations
09/15/2004CN1529707A Process for selective preparation of 3-(2)-propenyl-cephem compound
09/09/2004US20040176590 Manufacture of cefalosporins and intermediates
09/09/2004US20040175783 Generating 3-cephalosporin C derivatives which are used in the preparation of beta -lactam antibiotics using immobilized biocatalyst; solid phase synthesis
09/08/2004EP0831845B1 Diphosphonate derivatives of therapeutic agents
09/08/2004CN1165303C DNA binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents
09/07/2004US6787649 Simple production of cefotiam; acylating and deformylation
09/01/2004CN1524861A 7-phenylacetylamino-3-chloromethyl cephalosporanic acid p-methoxy benzyl ester powder and preparing process thereof
09/01/2004CN1524860A Cefetamet natrium, its preparing process and its application as antibacterial agent for injection
09/01/2004CN1164593C Method for synthesizing cefotaxime sodium
08/2004
08/26/2004WO2004035800A3 Intermediate cefdinir salts
08/26/2004US20040167327 Reacting 7-Amino-8-oxo-3-(tetrahydrofuran-2-yl)-5-thia-1-aza-bicyclo[4.2.0]octa-1(6),2,4-triene-2-carboxylic acid with 2-amino- alpha -(methoxyimino)-4-thiazoleacetic acid anhydride and O,O-diethyl hydrogenphosphorothioate in the presence of a solvent, a base, an coupling agent and catalyst
08/25/2004CN1163496C Vinyl-pyrrolidone cynnematin with alkali subtituent
08/18/2004EP1447406A1 3-Cephem derivative crystal
08/18/2004CN1522259A Cephem compounds
08/17/2004US6777549 Producing ceftriaxone or cefotaxime by amidation, cyclization, desilylation and optionally salt formation
08/12/2004WO2004067536A2 Carboxylic acid esters to improve bioavailability of pharmaceutical compounds
08/12/2004WO2004039811A3 A method for manufacture of ceftiofur
08/12/2004US20040157821 Sulfate of cephem compound
08/12/2004CA2509793A1 Carboxylic acid esters to improve bioavailability of pharmaceutical compounds
08/11/2004EP1444237A1 Novel c-3 s/o- and s/n formaldehe acetal derivatives of cephalo sporins and their use as antibiotics
08/11/2004EP1365764A4 Oral pharmaceutical composition of cefpodoxime proxetil
08/11/2004CN1520418A Process for prepn. of cefpodoxime acid
08/11/2004CN1519243A Crystal of 7-phenylacetyl amido-3-picolyl-3-cephalosporin-4-carboxylic p-methoxy benzyl ester crystal and preparation method
08/04/2004EP1442044A1 A process for the preparation of cefixime via alkyl-or aryl-sulfonates
08/04/2004EP1442029A1 A process for the preparation of cephalosporins side chains
08/04/2004EP1287003B1 Process for preparing a pure, pharmacopoeial grade amorphous form of cefuroxime axetil
08/04/2004CN1160361C Method for preparing highly purity cefpodoxime proxetil
07/2004
07/29/2004WO2004063203A1 Process for the preparation of cefotaxime sodium
07/29/2004WO2004062558A2 Process for enzymatic synthesis of βετα-lactam antibiotics
07/29/2004WO2004045533A3 Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
07/29/2004US20040147740 Method for storing quaternary ammonium salt
07/28/2004CN1515574A Substituted 7-acylamino-3-(methyldiazanediyl) methylcephalosporin and intermediate body with antibiotic action
07/28/2004CN1159320C Cephalo olefine onium salt compound and its preparing method, and method for synthesizing cephalo pyoxime with said compound
07/22/2004WO2004060896A1 A process for the manufacture of cefpodoxime proxetil
07/22/2004WO2003076640A8 A process for the preparation of cephalosporan acid derivatives from cephalosporin c
07/21/2004CN1513854A Cynnematin having chelated crystalline hydrate and its preparation method
07/21/2004CN1158289C Improved precipitation process of 7-aminocephalosporanic acid (7-ACA)
07/20/2004CA2094122C Direct compression method for preparing pills having cephalosporanic acid derivatives
07/15/2004WO2004058695A1 Novel intermediates for synthesis of cephalosporins and process for preparation of such intermediates
07/15/2004WO2004045536A3 Method and compositions for temporarily incapaciting subjets
07/14/2004EP1436299A1 Method for crystallization of 7-aminocephalosporanic acid
07/14/2004EP1061082B1 Process for the preparation of beta-hydroxy esters
07/14/2004CN1512996A Crystalline acid salts of cefdinir and process for preparing cefdinir using same
07/08/2004WO2004056835A1 Crystalline cefdinir salts
07/08/2004WO2004056834A1 A process for the preparation of cefpodoxime proxetil
07/08/2004US20040132996 Method for preparation of ceftiofur and salts thereof
07/08/2004US20040132995 Process for the preparation of cephalosporins
07/08/2004US20040132994 For therapy of of infectious diseases
07/08/2004US20040132992 Process for the selective preparation of 3-(z) propenyl-cephem compound
07/08/2004US20040132709 Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
07/08/2004US20040132707 Bactericides, especially gramnegative bacteria; side effect reduction
07/07/2004EP1435357A2 New process for the preparation of vinyl-pyrrolidinone cephalosporine derivatives
07/07/2004EP1434779A2 Cross-linked glycopeptide-cephalosporin antibiotics
07/01/2004US20040127703 optically active 3-amino-pyrrolidine derivatives can be safely manufactured in high yield on a technical scale by replacing allylamine with hydroxylamine or its acid addition salt
06/2004
06/30/2004EP1272495B1 A process for the preparation of highly crystalline sodium cefoperazone
06/30/2004CN1155603C Process for producing 3-cephem compounds
06/29/2004US6756047 Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
06/23/2004EP1430060A2 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors.
06/17/2004WO2004050663A2 An improved process for the preparation of cefuroxime sodium
06/17/2004WO2003040116A8 A process for the preparation of cephalosporins side chains
06/16/2004CN1505515A Oral pharmaceutical composition of cefpodoxime proxetil
06/15/2004US6750238 Aralkyl ester soft drugs
06/10/2004WO2004048387A1 An improved process for the preparation of cefpodoxime proxetil
06/09/2004EP1425285A1 Process for the preparation of crystalline cefuromixe axetil
06/09/2004CN1503802A Sulfate of cephem compound
06/03/2004WO2004046154A1 Novel amorphous hydrate of a cephalosporin antibiotic
06/03/2004WO2004046153A1 Prodrug esters of ceftriaxone
06/03/2004WO2004045536A2 Method and compositions for temporarily incapaciting subjets
06/03/2004WO2004045533A2 Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
06/03/2004US20040106790 Novel compounds and method for preparing 3-methylcephams
06/03/2004CA2503316A1 Method and compositions for temporarily incapacitating subjects
06/03/2004CA2503312A1 Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
06/02/2004EP1423395A1 Process for the preparation of highly pure cefuroxime axetil
06/02/2004CN1151845C Crystallographically stable amorphous sephalosporin compositions and process for producing the same
05/2004
05/26/2004EP1227100B1 3-cephem derivative crystal and method for preparing the same
05/21/2004WO2004041831A1 An improved process for the preparation of cefuroxime sodium
05/13/2004WO2004039997A1 Simple enzymatic process for preparing cefazolin
05/13/2004WO2004039814A1 Cephem compounds
05/13/2004WO2004039813A1 An improved process for the preparation of chloro methyl cephem derivatives
05/13/2004WO2004039812A1 Process for the preparation of 3-propenyl cephalosporin dmf solvate
05/13/2004WO2004039811A2 A method for manufacture of ceftiofur
05/13/2004US20040092735 Dissolving cefuroxime in water miscible solvent; charcoalizing solution; microfiltration; salt formation using mixture of sodium salts of weak acids; isolation, drying, precipitation
05/13/2004US20040092734 Cefpodixime proxetil
05/13/2004CA2503885A1 A method for manufacture of ceftiofur
05/12/2004CN1495187A Crystalline cefathiamidine and its production method
05/06/2004WO2004037833A1 Process for the preparation of cephalosporin antibiotics
05/06/2004WO2004037832A1 An improved process for the preparation of cefixime
05/06/2004WO2004037163A2 STERICALLY-AWKWARD β-LACTAMASE INHIBITORS
05/06/2004US20040087787 Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds
05/06/2004US20040087786 By reacting 4-methoxybenzyl-7-phenylacetamido-3-((triphenyl-phosporanylidene)methyl)-3 -cephem-4-carboxylate with acetaldehyde; deesterification; salt formation; neutralization; silylation; condensation with mixed anhydride
05/06/2004EP1416054A1 Simple enzymatic process for preparing cefazolin
05/06/2004EP1414827A2 Intermediates in cephalosporin production
05/05/2004CN1493574A Production method of cefathiamidine-18 crystal
05/05/2004CN1148371C Process for preparing 7-amino-3-methoxymethyl-3-cephem-4-carboxylic acid
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