Patents
Patents for C07D 499 - Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (3,448)
07/1990
07/31/1990US4945159 Penicillin, cephalosporins
07/31/1990CA1272189A1 Process for the preparation of sodium amoxycillin
07/24/1990US4943569 B-lactam compounds
07/17/1990US4942229 Dehydrobromination to form esters, phase transfer agents
07/17/1990CA1271742A1 Penem derivatives
07/10/1990US4940788 Process for preparing azetidinones
06/1990
06/28/1990WO1990006928A1 6-(1-carbamoyl-1-hydroxymethyl)penicillanic acid derivatives
06/26/1990CA1270814A1 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
06/20/1990EP0373388A2 Penem derivatives and process for their preparation
06/12/1990US4933444 Reacting halo-substituted compound with heterocycle in solvent
06/12/1990US4933333 β-lactam compounds
06/05/1990US4931555 Disulfide substituted oxazetidine derivatives
06/05/1990US4931434 Penem compounds
05/1990
05/26/1990CA2003836A1 Penem derivatives and processes for their preparation
05/22/1990US4927507 Antibiotic intermediate
05/22/1990CA1269364A1 Substituted penem derivatives and process for their preparation
05/15/1990US4925934 Deesterification
05/09/1990EP0367606A1 Process for the preparation of 6-oxopenicillanates
05/09/1990EP0367124A1 Penicillanic acid derivatives
05/09/1990CN1041944A Process for preparation of penems
05/08/1990US4923856 Antibiotics, beta-lactamase inhibitors
05/08/1990CA1268759A1 Copper-mediated oximation reaction
05/03/1990WO1990004594A1 Novel antimicrobial quinolonyl lactam esters
05/03/1990WO1990004591A1 Novel antimicrobial dithiocarbamoyl quinolones
05/02/1990EP0366643A2 Novel antimicrobial dithiocarbamoyl quinolones
05/02/1990EP0366641A2 Novel antimicrobial quinolonyl lactam esters
05/02/1990EP0366193A2 Novel antimicrobial quinolonyl lactams
05/02/1990EP0366189A2 Novel antimicrobial lactam-quinolones
05/01/1990US4921954 From sulfoxide intermediate
04/1990
04/30/1990CA2001642A1 Penicillanic acid derivatives
04/25/1990EP0365223A2 Process for the preparation of penems
04/25/1990CA1268183C Phosphorane intermediates for use in preparing penem antibiotics
04/17/1990US4918188 Intermediates for penicillin and carbapenicillin antibiotics
04/17/1990US4918067 Heterocyclic substituted penicillin antibiotics
03/1990
03/28/1990CN1040797A Preparation process of sodium salt penicillin
03/27/1990US4912213 Reacting lead with halogenated penicillanic acid derivative
03/27/1990US4912212 Cephem compounds
03/27/1990US4912211 Method for producing pure crystalline antibiotic products
03/27/1990CA1267138A1 PROCESS FOR THE PREPARATION OF .beta.-LACTAM COMPOUNDS
03/20/1990CA1266828A1 Pharmaceutical compositions of the prodrug type, a process for the preparation thereof, a process for the preparation of prodrug functioning compounds and compounds obtained herein
02/1990
02/22/1990WO1990001484A1 Crystalline (5r,6s)-2-carbamoyloxymethyl-6-[(1r)-hydroxyethyl]-2-penem-carboxylic acid and its pharmaceutical formulation
02/22/1990DE3921830A1 Verfahren zur herstellung von penemen A process for preparing penems
02/13/1990CA1265787A1 Method for producing chemical compounds
02/13/1990CA1265786A1 6-(substituted methylene)penems
02/06/1990US4898939 Process for preparing 2β-substituted-methylpenicillin derivatives
01/1990
01/30/1990US4897476 Process for preparing penems
01/23/1990US4895941 Antibiotics
01/23/1990US4895940 From (2-((triphenylmethylthio)-3-(dimethyltert-butylsiloxy)-ethyl)-2-azetidon-1 -yl)acetic acid esters
01/23/1990CA1264736A1 Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
01/09/1990CA1264319A1 2(n-heterocyclyl)penems
01/02/1990US4891369 Beta-lactamase inhibitors
12/1989
12/26/1989US4889929 Preparation of 1'-ethoxycarbonyl-oxyethyl esters of penicillins
12/20/1989EP0174342B1 Brain-specific analogues of centrally acting amines
12/19/1989US4888429 Process for producing allyl aminothiazole acetate intermediates
12/13/1989EP0345827A1 Process for the production of penem compounds
12/12/1989US4886793 Penem derivatives
12/05/1989CA1263644A1 2-azacycloalkylthiopenem derivatives
11/1989
11/29/1989CN1037514A Process for preparing 2 alpha-methyl-2 beta-(1,2,3-triazole-1-yl) methylpenam-3 alpha-carboxylic acid derivatives
11/28/1989CA1263399A1 Process for the manufacture of aminothiazole acetic acid derivatives
11/21/1989US4882325 Crystalline 1,1-dioxopenicillanoyloxymethyl 6-(d-amino-phenylacetamido)penicillanate napsylate and method of using the same
11/15/1989CN1037151A Process for preparation of beta-lactam derivatives
11/01/1989CN1036767A Process for preparing 2-substituted-methylpenicillin derivatives
10/1989
10/31/1989US4877783 β-lactam antibacterial agents
10/25/1989EP0338824A2 Esters of 6-beta-(alpha-oxyimino)-acylamino-penicillanic acid derivatives
10/25/1989EP0338735A1 Process for optically active 3-(methane-sulfonyloxy)thioland and analogs
10/24/1989US4876338 Synthesis of azetidinones using CuCl
10/18/1989EP0337704A2 Beta-lactam derivatives
10/18/1989EP0337643A2 6-Substituted acrylamido penicillanic acid derivatives, preparation and use
10/17/1989US4874877 Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
10/12/1989EP0313561A4 Compositions used in permanent structure altering of hair.
10/12/1989EP0311626A4 Use of N-alkyl-2-pyrrolidone in compositions for the permanent alteration of hair color.
10/11/1989EP0336511A2 Method of protection of the carboxy groups in the chemistry of beta-lactam compounds
10/10/1989US4873301 Optically active, ethylenically unsaturated polymers of amino penicillanic acid compounds
10/04/1989EP0335545A2 Pharmaceutical formulations for parenteral use
09/1989
09/26/1989US4870170 Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
09/26/1989CA1261318A1 Stereocontrolled acetoxyazetidinone process
09/19/1989US4868297 Catalytic hydrogenation
09/19/1989US4868296 Bactericides, beta-lactamase inhibitors
09/12/1989US4866170 Stable hydrate of penicillin derivative
09/12/1989US4866169 Antibiotics cephalosporins
09/06/1989EP0331395A1 Process for preparing 2-alpha-methyl-2-beta-(1,2,3-triazol-1-yl)methyl-penam-3-alpha-carboxylic acid derivatives
09/06/1989EP0331394A1 Process for preparing 2 beta-substituted-methylpenicillin derivatives
09/06/1989EP0331146A1 Process for preparation of beta-lactam derivatives
09/05/1989US4863965 Ibuprofen acid anhydrides and prodrug pharmaceutical composition containing the same
09/05/1989US4863915 β-lactam antibiotics
09/05/1989US4863914 Bactericides, antibiotics
08/1989
08/29/1989US4861768 2 β-substituted thiomethylpenicillin derivatives and their preparation and use
08/22/1989CA1258637A1 Compositions used in permanent structure altering of hair
08/16/1989EP0327766A2 Redox systems for brain-targeted drug delivery
08/08/1989US4855421 Chemical intermediates for penicillins
08/08/1989US4855419 Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active α-lactams
07/1989
07/26/1989CN1034131A Antibacterial lyophilized prepn.
07/18/1989US4849516 Penicillin and cephalosporin antibiotic intermediates
07/18/1989US4849419 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives
07/11/1989US4847266 Epimerization, purification
07/11/1989US4847247 Penicillin derivatives as anti-inflammatory and antidegenerative agents
07/04/1989US4845097 Phenoxyalkylaminopyrimidine derivatives and insecticidal and acaricidal compositions containing them
07/04/1989US4845088 Tetrazolyl derivatives of beta-lactams useful as elastase inhibitors
06/1989
06/27/1989CA1256426A1 Process for the preparation of 6-amino-penicillanic acid 1,1 dioxide by oxidation of 6-amino penicillanic acid,
06/21/1989EP0321187A1 6-(Substituted methylene)penems
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