Patents
Patents for C07D 499 - Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (3,448)
06/1988
06/21/1988CA1238311A2 6-aminopenicillanic acid esters
05/1988
05/31/1988US4748163 Novel β-lactam antibiotics
05/31/1988US4748162 6-substituted-2-carbaminidoyl-pen-2-em-3-carboxylic acids
05/17/1988CA1236828A2 Tetrabutylammonium 6-¬d-(2-¬1-methyl-2- methoxycarbonylvinylamino|-2-phenyl- or -2-¬4- hydroxyphenyl|acetamido)|penicillanate
05/17/1988CA1236827A2 Hydroxymethyl carbonate monopenicillanoyl intermediates
05/10/1988US4743598 Antibacterial 2-(azacycloalkyl) penems
05/10/1988CA1236450A1 Synthesis route for bacampicillin
05/03/1988US4742052 Antibacterial β-lactam compounds
04/1988
04/27/1988EP0265169A1 Oxadiazines & related compounds
04/27/1988EP0265166A1 Process for preparing penems
04/20/1988EP0263901A1 Conversion of cephalosporin hydrohalide salt to alkali metal salt
04/19/1988US4739047 Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
04/19/1988US4738959 Antibacterial penem derivatives
04/13/1988CN87106308A Hydrate of penicillin derivative and processs for preparing same
04/12/1988US4737585 Reacting an amine-solubilized amoxycillin trihydrate in an aprotic solvent/alcohol mixture; isolation
04/12/1988CA1235117A1 2-dioxacycloalkylthiopenem derivatives
04/06/1988EP0262696A2 Brain-specific drug delivery
04/06/1988EP0262202A1 Method for preparing penicillanic acid derivatives.
04/05/1988US4735938 2-aminothiazolyl-containing β-lactam antibiotics
03/1988
03/30/1988EP0261823A1 Stable hydrate of penicillin derivative and process for preparing same
03/29/1988US4734407 Alpha-aminoacyl-penicillins and cephalosporins
03/16/1988EP0260042A1 2-(1-Oxo-1-imino-1-thiacycloalkyl)-Thiopenem derivatives
03/15/1988CA1234099A1 Process for the production of penems
03/10/1988WO1988001615A1 Prodrug derivatives of carboxylic acid drugs
03/09/1988EP0259268A1 Process for the preparation of optically active beta-lactams
03/08/1988US4729990 Penicillin
03/02/1988EP0257602A1 (5R,6S,8R)-6-(1-hydroxyethyl)-2-(3R-pyrolidin-2-one-3-yl-)thiopenem-3-carboxylic acid
03/02/1988EP0257419A1 Process for the preparation of antibacterial 7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene derivatives
03/02/1988EP0257275A2 Cephalosporin and penicillin derivatives
02/1988
02/24/1988EP0256990A1 Pyridinio compounds
02/24/1988EP0256577A2 Brain-specific drug delivery
02/23/1988CA1233171A1 Process for the preparation of 6,6- dibromopenicillanic acid 1,1-dioxide
02/16/1988US4725678 Antibiotics
02/03/1988EP0255307A1 Process for the synthesis of penems
02/03/1988EP0255278A1 Synthesis of azetidinones
02/02/1988US4722924 Peptide substituted penicillins
01/1988
01/27/1988EP0254582A2 6 Beta-(alpha-oximino)-acylamino penicillanic-acid derivatives and starting compounds
01/19/1988US4720491 Fluoralkylatedcarbapenem derivatives
01/19/1988US4720490 Fluoralkylatedcarbapenem derivatives
01/14/1988WO1988000203A1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics
01/14/1988WO1988000186A1 Compositions used in permanent structure altering of hair
01/14/1988WO1988000185A1 Compositions used in permanent alteration of hair color
01/13/1988EP0252885A1 Bicyclic thiaaza compounds
01/12/1988US4719287 Solvent extraction
12/1987
12/22/1987US4714761 Oxidation, dehalogenation
12/16/1987EP0249358A1 Process for penem derivatives
12/15/1987US4713461 Process for producing glutaconic acid derivatives
12/15/1987US4713450 Antibiotics
12/15/1987US4713378 Penem derivatives
12/08/1987US4711956 Penicillin derivatives
12/08/1987US4711886 β-lactam derivatives as anti-inflammatory and antidegenerative agents
12/08/1987CA1230113A1 Method for producing chemical compounds
11/1987
11/24/1987US4708825 Process for the production of penicillins
11/19/1987EP0246187A2 2-Pyridyl penem compounds
11/04/1987EP0244195A1 2-Vinylpenams and process
11/04/1987EP0244113A1 B-lactam antibiotics
11/04/1987EP0243921A2 Crystalline hydrate of a penem derivative
11/04/1987EP0243686A2 Beta-lactam compounds, and their production
11/03/1987US4704456 Chloromethyl ester of sulfobactam
10/1987
10/22/1987WO1987006231A1 beta-LACTAM ANTIBIOTICS
10/22/1987WO1987006230A1 Method for preparing penicillanic acid derivatives
10/13/1987US4699904 Tetrazolyl derivatives of β-lactams useful as elastase inhibitors
09/1987
09/23/1987EP0238285A2 2-Heterocyclylthio penems
09/22/1987US4695628 Preparation of 6-amino-penicillanic acid-1,1-dioxide
09/22/1987US4695626 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters
09/22/1987CA1227194A1 Antibacterial penem derivatives
09/16/1987EP0237084A2 4-Bromomethyl-5-methyl-1,3-dioxolen-2-one, and a process for the production thereof
09/16/1987EP0236880A2 Penem derivatives
09/16/1987EP0236383A1 Method for preparing 6beta-halopenicillanic acids and salts thereof.
09/15/1987CA1226861A1 Process for the production of penem compounds
09/09/1987EP0236074A1 2Beta-substituted thiomethylpenicillin derivatives and their preparation and use
09/08/1987US4692442 6-substituted penem compounds
09/01/1987US4690922 2-(heterocycloalkylthio)penems
08/1987
08/26/1987CN87100860A Process for manufacture of carboxylic acid amides
08/19/1987EP0233155A1 Aminoacyloxymethyl compounds
08/19/1987EP0232966A1 Process for the preparation of penem compounds and intermediates for this preparation
08/12/1987EP0231845A2 Process for the preparation of carboxylic-acid amides
08/12/1987EP0231244A1 6-alkylidene penems
08/11/1987CA1225392A1 Antibacterial penem derivatives
08/04/1987US4684728 Solubilizing biologically active compounds with reactive hydrogen atoms
08/04/1987US4684664 Derivatives of β-(4-isocyano-1,2,3,4-diepoxycyclopentyl) acrylic acid
08/04/1987US4684640 Antibiotics, beta-lactamase inhibitors
08/04/1987US4684639 Antibiotics
07/1987
07/28/1987USRE32465 AZA penem compounds
07/28/1987US4683303 Reduction process for the preparation of 4-unsubstituted azetidin-2-ones
07/28/1987US4683226 6-hydroxyalkyl-2-(substituted-thio)penem-3-carboxylic acids
06/1987
06/23/1987US4675398 For antibiotics
06/23/1987US4675396 7-Oxo-4-thia-1-azabicyclo(3,2,0)heptane derivatives
06/23/1987US4675317 2-unsaturated alkylthio-pen-2-em-3-carboxylic acids
06/23/1987US4675186 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
06/09/1987US4672114 Process for the preparation of pure 6-β-halopenicillanic acids and salts thereof
06/09/1987CA1222745A1 PROCESS FOR THE PREPARATION OF .beta.-LACTAM COMPOUNDS
06/03/1987EP0224390A1 Penicillins
06/03/1987EP0224283A2 Brain-specific drug delivery
06/02/1987US4670431 Beta-lactam antibacterial agents
06/02/1987CA1222507A1 .beta.-LACTAM ANTIBIOTICS, PROCESSES FOR THEIR PREPARATION AND AGENTS WHICH CONTAIN THESE COMPOUNDS
05/1987
05/27/1987EP0223397A2 Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
05/26/1987US4668514 Penicillin derivatives
05/20/1987EP0222425A2 Brain-specific drug delivery
05/20/1987EP0222022A1 Process for producing beta-lactam derivatives
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