Patents
Patents for C07D 499 - Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (3,448)
09/1994
09/20/1994US5348949 Method of preparing N-oxo-tetrahydro-β-carbolines
09/07/1994CN1025856C Extractent and process for extracting penisiuin and its application
08/1994
08/31/1994EP0612749A1 Method of desilylating silylether compounds
08/23/1994CA1331564C Redox systems for brain-targeted drug delivery
08/03/1994CN1090285A Quinolonecarboxylic acids
07/1994
07/20/1994EP0524959B1 Process for sultamicillin intermediate
07/13/1994CN1089267A Chemical compounds
07/12/1994US5328908 Antimicrobial quinolone thioureas
07/05/1994US5326884 Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
06/1994
06/15/1994CN1025032C Process for preparing 2-methoxymethyl-penem derivatives
06/07/1994US5319103 Intermediate diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-carboxylic acids
06/01/1994CN1024754C Antibacterial lyophilized prepn.
05/1994
05/18/1994EP0597401A2 Production of penem
05/18/1994EP0597051A1 Hydroxy protecting group removal in penems
05/12/1994CA2102827A1 Production of penem
05/11/1994WO1994010178A1 6-(substituted methylene) penems and intermediates
05/11/1994EP0596262A1 Process for the preparation of sterile beta-lactam antibiotics
05/04/1994EP0594563A1 Asymmetrical ureas, method for the preparation and utilization of the same
04/1994
04/27/1994EP0593457A1 Antimicrobial quinolone thioureas
04/21/1994DE3348300C2 Use of alpha-bromo:di:ethyl carbonate for Bacampicillin prepn. from ampicillin
04/13/1994EP0592167A1 Antibiotic pyrrolidinylthiopenem derivatives
04/13/1994EP0591808A1 Quinolonecarboxylic acids
04/12/1994US5302711 Deesterification of the blocked 3- or 4-carboxylate derivative of cepham or penam with lithium iodide in a nonbasic solvent having a dielectric constant of between 0 and 15
04/12/1994US5302588 Antibacterial agent
04/10/1994CA2107812A1 Quinolone carboxylic acids
04/08/1994CA2106330A1 Antibiotic compounds
04/05/1994US5300497 Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria
03/1994
03/31/1994WO1994006803A1 Penem derivatives, their preparation and pharmaceutical compositions containing them
03/31/1994CA2144961A1 Penem derivatives, their preparation and pharmaceutical compositions containing them
03/24/1994DE4231295A1 New antibacterial(s) with high stability to beta-lactamase - are 6-(alpha-(aryl-aminocarbonyl (vinyl)carbonylamino) -alpha-phenyl)-penicillanic acid derivs.
03/16/1994EP0587436A1 Process for preparing carbapenem and penem compounds and new compounds involved in that process
03/15/1994US5294644 Surface active lactams
03/10/1994CA2105746A1 Process for preparing carbapenem and penem compounds and new compounds involved in that process
03/09/1994EP0262207B1 Beta-lactam antibiotics
03/08/1994US5292924 Optically active N-α-fluoroacryloylamino acid polymers for the resolution of racemates
03/08/1994CA1327566C Brain-specific drug delivery
02/1994
02/22/1994US5288860 Process for preparing thiazolino azetidinone and 2-exo-methylenepenam derivative
02/17/1994WO1994003168A1 5 s penem derivatives, their preparation and use
02/15/1994US5286857 Intermediate for the preparation of penems
02/09/1994CN1081668A (1'R,3S,4R)4-acylthio-azetidinones
01/1994
01/25/1994US5281703 Process for making antimicrobial quinolonyl lactams
12/1993
12/28/1993US5273973 Antimicrobial quinolonyl esters
12/23/1993WO1993025523A1 4-acylthio azetidinones
12/23/1993CA2115173A1 4-acylthio azetidinones
12/22/1993EP0574940A1 Method for removing the protecting group for carboxyl group
12/22/1993EP0574784A1 (1'R,3S,4R)4-acylthio azetidinones
12/21/1993CA1325422C Prodrug derivatives of carboxylic acid drugs
12/08/1993EP0385999B1 Application of 4- 1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active beta-lactams
12/08/1993CN1023016C Process for preparing diastereomeric 5R, 6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
12/08/1993CN1023015C Process for preparation of penems
12/08/1993CN1022973C Method and apparatus for preparing food foodstuffs
12/07/1993CA1325077C Beta-lactam derivatives
11/1993
11/30/1993US5266693 6-diazo-penicillanic acid 1,1-dioxide derivatives
11/25/1993WO1993023406A1 Hydroxy protecting group removal in penems
11/25/1993CA2110989A1 Hydroxy protecting group removal in penems
11/24/1993CN1022836C Process for preparing 2-subs-methylpenicillin derivatives
11/24/1993CN1022835C Process for preparing 2 alpha-methyl-2 beta-(1,2,3-triazole-1-yl) methylpenam-3 alpha-carboxylic acid derivatives
11/09/1993US5260438 With fluorine compound
11/03/1993EP0567949A1 Method for removing the protecting group for hydroxy group
10/1993
10/27/1993CN1022568C Synthesis of tricyclazole
09/1993
09/29/1993CN1076698A Condensation process for semi-synthetic penicillin
09/08/1993EP0559533A1 Process for preparing beta-lactam derivative and synthetic intermediate thereof
09/07/1993CA2085540A1 Process for preparing beta-lactam derivative and synthetic intermediate the reof
09/01/1993CN1021968C Preparation process of sodium salt penicillin
08/1993
08/25/1993EP0557035A2 An ester cleavage process for use with beta-lactams
08/19/1993CA2089540A1 Ester cleavage process for use with .beta.-lactams
08/18/1993EP0555421A1 Penem derivatives
08/11/1993CN1075146A Process for making antimicrobial quinolonyl lactams
08/04/1993CN1021735C Process for preparation of cephalosporin compounds
07/1993
07/21/1993CN1021655C Composition and method for extracting penicillin
06/1993
06/23/1993CN1073442A Method for preparing 3S,4R-N-oxalyl-3-ethyl-4-|1R-oxo-3S-thiolanylthio (thiocarbonyl)-thio¨-2-azetidinones
06/16/1993CN1021225C Hydrate of penicillin derivative and process for preparing same
06/09/1993EP0544907A1 Antibacterial penem esters derivatives
06/09/1993EP0544906A1 Penem compounds
06/09/1993EP0544905A1 Antibacterial penem compounds
06/01/1993US5215997 Synthesis of beta-lactam compounds
06/01/1993US5215891 Enzymatic hydrolysis of ester group of the 2-substituent by lipase enzyme
04/1993
04/29/1993WO1993008196A1 Penicillin g ester
04/27/1993US5206361 Thiazolinoazetidinone derivative
04/21/1993EP0537255A1 PROCESS FOR PREPARATION OF $g(b)-LACTAMS
04/15/1993WO1993007154A1 Process for making antimicrobial quinolonyl lactams
04/15/1993CA2120493A1 Process for making antimicrobial quinolonyl lactams
04/13/1993CA1316171C Cephalosporin derivatives
04/07/1993EP0311640B1 Higher alkyl pyrrolidone extractants for water soluble phenolic or carboxylic antibiotics
04/06/1993US5200403 Administering to prevent destruction of beta-lactam antibiotics
03/1993
03/30/1993US5198544 Process for the preparation of penem compounds
03/23/1993US5196530 Cyclization with reducing metal
03/04/1993WO1993004070A1 Substituted acrylamido-penicillanic acid derivatives
03/02/1993US5191077 Systemic bactericides
03/02/1993US5191075 Preparation of penicillins
02/1993
02/18/1993WO1993003042A1 6-ethylidene penem derivatives
02/09/1993US5185330 Penam derivatives and salts thereof, and antibacterial agent comprising the same
02/03/1993EP0525057A1 Antimicrobial quinolonyl lactams
02/03/1993EP0524959A1 Process for sultamicillin intermediate.
01/1993
01/21/1993WO1993001174A1 Thiazolidine derivatives and their use as anti-viral compounds
01/19/1993US5180719 Antimicrobial quinolonyl lactam esters
01/07/1993EP0521018A1 Process for preparing penem esters
01/05/1993US5176739 Dicarboximides and their use as herbicides
01/05/1993CA1312288C Compositions used in permanent alteration of hair color
12/1992
12/23/1992EP0519516A1 Penem derivatives
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