| Patents for C07D 499 - Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (3,448) |
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| 06/21/1989 | EP0321186A1 6-(Substituted methylene)penems |
| 06/20/1989 | US4841042 Process for the preparation of carbapenem intermediates |
| 06/20/1989 | US4840944 Antibacterial beta-lactams, pharmaceuticals thereof and methods of using them |
| 06/14/1989 | EP0320497A1 Substituted 2-thioxopenams, intermediates therefrom and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems |
| 06/07/1989 | EP0318767A2 Esters of pharmacologically active carboxylic acids splittable under physiological conditions |
| 06/06/1989 | US4837317 Process for the preparation of 6-[D(-)alpha-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-alpha-phenylacetamido]-penicillanic acid and intermediates useful in this process |
| 06/06/1989 | US4837215 Penem derivatives |
| 05/24/1989 | EP0317484A2 N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof |
| 05/23/1989 | CA1254553A1 Penem compounds, methods for their preparation and pharmaceutical compositions containing them |
| 05/16/1989 | US4831025 Crystalline penicillin derivative tosylate hydrates |
| 05/09/1989 | CA1253856A1 Brain-specific drug delivery |
| 05/03/1989 | EP0313561A1 Compositions used in permanent structure altering of hair. |
| 05/02/1989 | US4826833 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof |
| 05/02/1989 | US4826832 Penen compounds |
| 04/19/1989 | EP0311626A1 Use of N-alkyl-2-pyrrolidone in compositions for the permanent alteration of hair color |
| 04/12/1989 | EP0310948A2 Process for the preparation of optically pure phenyl ring-substituted phenyl alamine derivatives |
| 04/12/1989 | EP0310909A2 Heteroannelated phenyl glycine beta-lactam antibiotics, process for their preparation and their use as therapeutical agents |
| 04/11/1989 | US4820857 Intermediates for esters of penicillins, cephalosporins; bacampicillin |
| 04/11/1989 | US4820701 Penam derivatives |
| 04/11/1989 | CA1252471A1 Process for the preparation of azetidinones |
| 04/04/1989 | CA1252096A1 Process and intermediates for the preparation of penem derivatives |
| 03/28/1989 | US4816580 Improved method for preparing penicillanic acid derivatives |
| 03/28/1989 | US4816452 Aminothiazole substituted penicillins and antibacterial compositions thereof |
| 03/23/1989 | DE3729338A1 Process for the removal of penicillin G from a fermentation medium by extraction |
| 03/21/1989 | US4814442 6-hydroxyethyl-2-substituted thio-penem-3-carboxylates |
| 03/15/1989 | EP0306924A1 Process for preparing penicillanic acid derivatives |
| 03/07/1989 | CA1250839A1 Fluoralkylated carbapenem derivatives |
| 02/28/1989 | US4808724 2-aminothiazolyl-containing β-lactam antibiotics |
| 02/28/1989 | US4808711 Cephalosporin derivatives |
| 02/21/1989 | US4806637 6-(Hydroxyethyl)-2-(heterocyclylthio)-penem-3-carboxylates |
| 02/01/1989 | CN1030760A New method for prepg. cephalkenes and new ceplalosporin derivatives |
| 01/31/1989 | US4801704 Penicillins |
| 01/26/1989 | DE3823612A1 Substituierte 6-alkyl-2-pyridyl-penem-3-carbonsaeure-derivate, ihre herstellung und sie enthaltende pharmazeutische oder veterinaere zusammensetzungen Substituted 6-alkyl-2-pyridyl-penem-3-carbonsaeure derivatives, their preparation and pharmaceutical or veterinary compositions containing them |
| 01/24/1989 | US4800199 3-[2-thiazoloamino]-8-oxo-7-substituted-5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid and salts thereof and diphenylmethyl esters thereof |
| 01/19/1989 | DE3822735A1 6 (alpha)- und 6ss-(substituierte methyl)-penicillansaeurederivate, verfahren zu deren herstellung und pharmazeutische oder veterinaere zubereitungen, die diese enthalten 6 (alpha) - and 6ss- (substituted methyl) -penicillansaeurederivate, processes for their preparation and pharmaceutical or veterinary formulations containing them |
| 01/19/1989 | DE3822595A1 Verfahren zur herstellung von 6-((1r)-hydroxyethyl)-penemsaeuren -penemsaeuren ((1r) hydroxyethyl) - Process for the preparation of 6 |
| 01/17/1989 | US4798828 Heterocyclic-methylene-penems |
| 01/10/1989 | US4797396 Inhibition of elastase, antibiotics |
| 01/10/1989 | US4797394 6-(1-carbamoyl-1-hydroxymethyl)penicillanic acid derivatives |
| 01/10/1989 | CA1248520A1 Penem compounds, pharmaceutical compositions containing them, processes for their preparation |
| 01/04/1989 | CN1030079A Process for preparing 2-methoxymethyl-penem derivatives |
| 01/03/1989 | US4795748 Antibacterial 7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives |
| 12/29/1988 | WO1988010256A1 Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active beta-lactams |
| 12/28/1988 | EP0297042A1 Substituted penem compounds |
| 12/28/1988 | CA1247597A .beta.-LACTAMASE INHIBITING 6-(ALKOXYAMINO- METHYL)PENICILLANIC ACID 1,1-DIOXIDE AND DERIVATIVES |
| 12/27/1988 | US4794179 2-(1-oxo-3-thiolanyl)-2-penem antibiotics |
| 12/27/1988 | US4794109 Antibiotic |
| 12/27/1988 | US4793994 Compositions used in permanent structure altering of hair |
| 12/21/1988 | CN88102863A Diasteriomeric 5r, 6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids |
| 12/21/1988 | CN88101104A Pharmaceutical composition pharmaceutical granulate and process for their preparation |
| 12/14/1988 | EP0295100A1 Methoxymethyl compounds |
| 12/14/1988 | EP0294934A2 Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids |
| 12/14/1988 | EP0294789A1 Process for preparing 6-/D(-)-Alpha-(4-ethyl-2,3-dioxo-1-piperazine-carboxamido)-phenylacetamido/pennicillanic acid |
| 12/13/1988 | CA1246546A1 2-alkylthiopenem derivatives |
| 12/13/1988 | CA1246488A1 Process for preparing 2,2-bishalomethylpenam derivatives |
| 12/07/1988 | EP0293532A1 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives |
| 11/29/1988 | US4788282 Carbapenicillins |
| 11/29/1988 | CA1245630A1 Crystalline modification of ceftazidim |
| 11/17/1988 | WO1988008845A1 Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids |
| 11/17/1988 | EP0291304A1 Process for the conversion of the E-isomer of 6-(substituted methylene)-2-penems into the Z-isomer |
| 11/09/1988 | EP0290385A1 Process for preparing 4-acyloxy-3-hydroxyethyl-azetidinones |
| 11/01/1988 | US4782146 From azetidinones via 1-aza-4,5-dithiabicyclo(4.2.0)oct-2-en-8-one-2-carboxylates |
| 11/01/1988 | US4782145 Process for penem derivatives |
| 11/01/1988 | US4782050 6-beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof |
| 10/26/1988 | EP0287734A1 2-Beta-substituted methyl-penam derivatives |
| 10/18/1988 | CA1243299A1 Process for the dehalogenation of 6,6- dibromopenicillanic acid 1,1-dioxide |
| 10/06/1988 | WO1988007534A1 Beta-lactam epoxides |
| 10/04/1988 | US4775527 N-alkyl pyrrolidone as swelling and penetrating conditioner |
| 09/27/1988 | US4774238 Heterocyclic-methylene-penems |
| 09/20/1988 | US4772692 Intermediate compounds for the preparation of antibacterial penem derivatives |
| 09/20/1988 | US4772597 Antibiotics |
| 09/13/1988 | US4771134 Penicillin antibiotic intermediate |
| 09/13/1988 | US4771046 Antibiotics |
| 09/07/1988 | EP0281234A1 Optically active, ethylenically unsaturated monomers and polymers thereof |
| 09/07/1988 | EP0281200A1 Pharmaceutical composition, pharmaceutical granulate and process for their preparation |
| 09/06/1988 | US4769325 2-(Allenyl)penicillins |
| 09/06/1988 | CA1241656A1 Fluoralkylatedcarbapenem derivatives |
| 08/30/1988 | US4767853 Ozonolysis, hydrolysis, decyclization |
| 08/17/1988 | EP0278911A1 Bicyclic beta-lactam carboxylic acids |
| 08/17/1988 | EP0278243A1 Medical preparation comprising aspoxicillin, a method for its preparation, and the use of such a preparation for the manufacture of a medicament |
| 08/16/1988 | CA1240667A1 Penam derivatives and process for preparing the same |
| 08/10/1988 | CN88100588A Process for 6-beta (substated)-s-hydroxymethyl-penicillanic acid and its derivatives |
| 08/09/1988 | US4762921 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives |
| 08/09/1988 | US4762920 Beta-lactamase inhibitor, synergistic with penicillin antibiotics and bactericides |
| 08/09/1988 | US4762827 Bactericides, antibiotics |
| 08/03/1988 | EP0276993A1 Process for preparing azetidinones |
| 08/03/1988 | EP0276942A1 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof |
| 08/02/1988 | US4761408 Penicillin derivatives, bactericides |
| 07/27/1988 | CN85106479B Crystalline d-6 (alpha-((2-aldo-3-furfurylidene-amino-1-imidazolidinyl) carbonyl amino)-2 thienylacetamido)-penicillanic acid salt with sodium, process thereof and use as medicine |
| 07/26/1988 | US4760140 3-substituted-7-[5-substituted-2-thiazolyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, diphenylmethyl esters |
| 07/26/1988 | US4760058 A lithium, sodium or potassium salt of (5R,6S)-6(1R)-hydroxyethyl)-2-methylthio-2,2-formyl penam-3-carboxylate |
| 07/20/1988 | EP0275233A1 2-Heterocyclylalkyl-2-penem compounds |
| 07/20/1988 | EP0275002A1 Process for the production of 7-oxo-4-thia-1-aza-bicyclo [3.2.0] hept-2-ene derivatives |
| 07/19/1988 | CA1239392A1 Penicillin derivatives and process for preparing the same |
| 07/06/1988 | EP0273747A1 Penem derivatives, production and use thereof |
| 07/06/1988 | EP0273599A1 Process for preparing 2beta-substituted-methyl-penicillin derivatives |
| 07/06/1988 | EP0273156A2 Method for producing pure crystalline products |
| 07/06/1988 | CN86106583B Process for 2-(1-ox0-3-thiolanyl)-2-penem antibiotics |
| 06/28/1988 | CA1238632A1 Preparation of 1'-ethoxycarbonyloxyethyl esters of penicillins and novel intermediates |
| 06/22/1988 | EP0272016A1 2beta-substituted-methylpenicillanic acid derivatives, and salts and esters thereof |