Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484)
09/2003
09/16/2003CA2293835C Stabilized carbapenem intermediates and synthetic use
09/04/2003WO2003072015A2 Compounds useful in the treatment of anthrax
09/04/2003US20030166923 Bactericides
09/04/2003CA2465854A1 Compounds useful in the treatment of anthrax
09/03/2003EP1340757A1 1-methylcarbapenem derivatives
09/03/2003EP1340756A1 Novel beta-lactam compounds and proecss for producing the same
08/2003
08/27/2003EP1338596A1 Process for producing carbapenem-type antibacterial
08/21/2003US20030158174 Crystalline 1-methylcarbapenem derivatives
08/20/2003EP1336612A1 Novel carbapenem derivatives
08/14/2003US20030153191 Antibiotics; storage stability
08/13/2003EP1334105A1 Process for the preparation of crystalline n-formimidoyl thienamycin monohydrate (imipenem monohydrate)
08/07/2003US20030149016 Having wide range of anti-gram-positive and gram-negative microbial activities
08/06/2003EP1332145A1 Process for formulation of antibiotic compounds
07/2003
07/31/2003US20030144264 Carbapenems containing a carboxy substituted phenyl group and useful for treating bacterial infections in mammals and humans
07/30/2003EP0946558B1 Ethylidene derivatives of tricyclic carbapenems
07/29/2003US6599895 β-lactam compounds and process for producing the same
07/23/2003EP1015452B1 Optionally protected 3-hydroxymethyl carbapenems and synthesis
07/23/2003CN1432016A Novel crystal form of pyrrolidylthiocarbapenem derivative
07/22/2003US6596718 7-Morpholin-4yl-benzothiazole amide derivatives
06/2003
06/26/2003WO2003052113A1 Cyclisation process for the preparation of c-2 beta-lactam compounds
06/25/2003EP1100800B1 Novel c-2 s/o- and s/n formaldehyde acetal derivatives of carbapenem-3-carboxylic acids and their use as antibiotics and beta-lactamase inhibitors
06/25/2003CN1112364C 1,3,4-thiadizole carbapenem compound and its preparing process and use
06/19/2003WO2003026572A3 Crystalline forms of ertapenem sodium
06/05/2003WO2003045385A1 Benzothiazole derivatives
06/05/2003CA2467825A1 Benzothiazole derivatives
05/2003
05/22/2003WO2003042215A1 Process for the preparation of crystalline imipenem
05/22/2003WO2003016272A3 Improving bioavailability of carbapewem salts by nanofiltration
05/22/2003CA2467427A1 Process for the preparation of crystalline imipenem
05/21/2003EP1244444A4 Process for formulation of carbapenem antibiotic compositions
05/20/2003US6566509 Compound for use as bactericide
05/15/2003WO2003040146A1 Novel carbapenem compounds
05/07/2003EP0987267B1 Carbapenem compounds, use thereof, and intermediate compounds of the same
04/2003
04/30/2003CN1107067C Carbapenem compounds, use and intermediate compounds thereof
04/29/2003US6555700 1,3-propane diol esters and ethers and methods for their use in drug delivery
04/29/2003CA2083980C Aminoalkylpyrrolidinylthiocarbapenem derivatives
04/23/2003EP1028962B1 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
04/16/2003CN1105719C Stabilized carbapenem intermediates and synthetic use
04/15/2003US6548492 Process for formulation of carbapenem antibiotic compositions
04/03/2003WO2003027067A2 Process for making carbapenem compounds
04/03/2003WO2003026572A2 Crystalline forms of ertapenem sodium
03/2003
03/18/2003CA2065079C Polycyclic carbapenem compounds, their production and use
03/11/2003US6531594 Process for producing 1H-3-aminopyrrolidine and derivatives thereof
03/11/2003US6531466 E.g., a 1-aza-10-(1-hydroxyethyl-11-oxo-4-(het-methylene)-tricyclo(7.2 .0.0(3,8))undec-2-ene-2-carboxylate; good activity against grampositive bacteria such as methicillin-resistant Staphylococcus aureus and epidermidis
03/05/2003EP1286989A2 Prodrug of an ice inhibitor
02/2003
02/27/2003WO2003016312A1 Process for preparation of carbapenem antibiotics
02/27/2003WO2003016272A2 Improving bioavailability of carbapewem salts by nanofiltration
02/18/2003US6521612 Antibiotic compounds
02/12/2003EP1023294B1 Carbapenem derivatives and a preparation method thereof
02/12/2003EP0937078B1 Tricyclic carbapenem compounds
02/12/2003CN1101397C Preparation of beta-methyl carbepenem intermediate
02/12/2003CN1101189C Anti-helicobacter pylori compositions containing 1-methylcarbapenem derivatives as active ingredient
02/06/2003US20030027809 1-hydroxyethyl-2(imidazo(5,1b)thiazol-2-yl-1-carbapen-2-em-3-c carboxylic acid or salt, excellent antibiotic activity against a wide spectrum of bacteria
01/2003
01/30/2003US20030022881 Novel carbapenem derivatives of quarternary salt type
01/29/2003EP0641795B9 Carbapenem derivative
01/07/2003US6504027 Decarboxylation process for synthesizing carbapenem antibiotics
01/02/2003EP1270575A1 Novel crystal form of pyrrolidylthiocarbapenem derivative
12/2002
12/24/2002CA2252402C Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
12/18/2002EP1023062B1 Antibacterial carbapenems, compositions and methods of treatment
12/18/2002EP0725783B1 2-(pyrazol-3-yl)carbapenem derivatives
12/11/2002CN1095843C 1-methylcarbpenem derivatives
12/03/2002US6489471 A process of synthesizing a carbapenem compound of formula (6) is disclosed, wherein r represents h or methyl, p and p* independently represent h or protecting groups and each r.sup.1 is independently selected from: h, halo, oh, op
12/03/2002US6489318 Ethylidene derivatives of tricyclic carbapenems
11/2002
11/28/2002WO2002094829A1 Carbapenem compound
11/28/2002WO2002094828A1 Process for the preparation of imipenem
11/28/2002WO2002094773A2 Process for the isolation of crystalline imipenem
11/28/2002CA2448670A1 Carbapenem compound
11/28/2002CA2447673A1 Process for the isolation of crystalline imipenem
11/28/2002CA2447227A1 Process for the preparation of imipenem
11/26/2002US6486150 Process for formulation of antibiotic compounds
11/19/2002US6482818 C-2 S/O-and S/N formaldehyde acetal derivatives of carbapenem-3-carboxylic acids and their use as antibiotics and β-lactamase inhibitors
11/12/2002US6479478 A 1-methylcarbapenem compound having sufficiently high degrees of both antibacterial activity and resistance to dehydropeptidase (dhp) in the living body
11/06/2002CN1093861C 1-methylcarbapenem derivatives
10/2002
10/23/2002EP1251134A1 Novel carbapenem derivatives of quaternary salt type
10/23/2002EP1251133A1 Novel carbapenem derivatives
10/10/2002US20020147333 Therapy for bacteria infections
10/02/2002EP1244444A1 Process for formulation of carbapenem antibiotic compositions
10/02/2002CN1372560A Crystalline 1-methylcarbapenem compounds
10/01/2002US6458780 Carbapenem derivatives
09/2002
09/26/2002WO2001072750A1 Novel crystal form of pyrrolidylthiocarbapenem derivative
09/25/2002EP0641795B1 Carbapenem derivative
09/24/2002CA2103223C Crystalline carbapenem derivative
09/18/2002EP0823889B1 1,3-propane diol derivatives as bioactive compounds
09/12/2002US20020128283 Process improvement in the preparation of (4R, 5S, 6S)-3-[[(2R,3R)-2-[[[(S)-2-amino-3-methyl-1-oxobutyl]amino]methyl]tetrahydro-3-furanyl]thio]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
09/12/2002US20020128254 Antibiotics, bactericides
09/11/2002EP0758651B1 Crystal of pyrrolidylthiocarbapenem derivative, lyophilized preparation containing said crystal, and process for producing the same
09/04/2002EP0913151B1 Anti-helicobacter pylori compositions containing 1-methylcarbapenem derivatives as the active ingredient
09/04/2002EP0882728B1 1-methylcarbapenem derivatives
08/2002
08/21/2002EP0900797B1 A 1-methylcarbapenem derivative
08/21/2002CN1365362A Process for the preparation of basic anti-biotic-inorganic acid and intermediate oxalates
08/20/2002US6436921 Have low minimum inhibitory concentrations for grampositive and gramnegative strains, are stable against degradation by renal dehydropeptidase-i and have excellent bioavailability
08/07/2002EP0760370B1 Novel carbapenem derivatives
07/2002
07/25/2002WO2002057266A1 Improved process for carbapenem synthesis
07/23/2002CA2107675C Antibiotic carbapenem derivatives
07/11/2002WO2002053566A1 Novel carbapenem compounds
07/11/2002CA2432076A1 Novel antibacterial carbapenem compounds
06/2002
06/25/2002US6410525 Carbapenem derivatives, utilization thereof and intermediate compounds of the same
06/25/2002CA2227994C Carbapenem antibiotic, composition and method of preparation
06/20/2002WO2002048149A1 NOVEL ss-LACTAM COMPOUNDS AND PROCESS FOR PREPARING THE SAME
06/06/2002WO2002044178A1 NOVEL β-LACTAM COMPOUNDS AND PROCESS FOR PRODUCING THE SAME
05/2002
05/30/2002WO2002042312A1 Novel carbapenem derivatives
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 ... 25