| Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484) |
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| 04/20/2005 | CN1608066A Process for the preparation of crystalline imipenem |
| 04/14/2005 | WO2005033120A1 Method for producing carbapenem derivative |
| 04/12/2005 | CA2322658C Process for synthesizing carbapenem antibiotics |
| 04/12/2005 | CA2127193C 2-[1-(1,3-thiazolin-2-yl)azetidin-3-yl] thio-carbapenem derivatives |
| 03/31/2005 | US20050070519 Cyclisation process for the preparation of c-2 beta-lactam compounds |
| 03/30/2005 | CN1602312A Process for making carbapenem compounds |
| 03/09/2005 | CN1192030C Novel crystal of pyrrolidylthiocarbapenem derivative |
| 03/03/2005 | WO2005019217A1 Crystal of 1-methyl carbapenem compound |
| 03/03/2005 | CA2644316A1 Crystal of 1-methyl carbapenem compound |
| 02/17/2005 | CA2534528A1 3-(indol-1-yl)-4-(indol-3-yl)-pyrrole-2,5-diones,3-(benzimidazol-1-yl)-4-(indol-3-yl)-pyrrole-2,5-diones, and 3-(indolin-1-yl)-4-(indol-3-yl)-pyrrole-2,5-diones; their preparationand use as modulators of apoptosis |
| 01/27/2005 | US20050020566 Novel carbapenem compounds |
| 01/12/2005 | CN1563008A Method of ion liqid extraction for separating penicillin |
| 01/06/2005 | US20050004359 Process for the preparation of crystalline imipenem |
| 01/05/2005 | EP1442038A4 Crystalline forms of carbapenem antibiotics and methods of preparation |
| 12/29/2004 | EP1244444B1 Process for formulation of carbapenem antibiotic compositions |
| 12/23/2004 | WO2004067536A3 Carboxylic acid esters to improve bioavailability of pharmaceutical compounds |
| 12/22/2004 | EP1489061A1 Process for producing cyclic compound |
| 12/22/2004 | CN1181072C Process for preparation of basic anti-biotic-inorganic acid and intermediate oxalates |
| 12/02/2004 | US20040242865 Purity; crystallization from solvent |
| 11/30/2004 | US6825187 Carbapenem derivatives substituted at the 2-position with a substituted imidazo(5,1-b)thiazole group; use against antibiotic resistant staphylococcus aureus and pseudomonas aeruginosa, enterococci and influenza virus |
| 11/25/2004 | US20040235817 Crystalline forms of ertapenem sodium |
| 11/10/2004 | EP1474426A2 Process for making carbapenem compounds |
| 11/04/2004 | US20040220168 Process for the preparation of imipenem |
| 10/26/2004 | CA2303446C Carbapenem derivatives and a preparation method thereof |
| 10/21/2004 | CA2519794A1 Novel carbapenem compounds |
| 10/13/2004 | EP1251133B1 Novel carbapenem derivatives |
| 10/07/2004 | US20040198973 free from the two disadvantages of column chromatography and recovery of a difficulty soluble salt; reacting a diphenylphosphate carbapenem with a mercapto-compound of given formula; deprotecting and purifying the resulting compound by crystallization |
| 10/06/2004 | EP1353923B1 Improved process for carbapenem synthesis |
| 09/29/2004 | EP1201665B1 Process for the preparation of basic antibiotic-inorganic acid addition salts and intermediate oxalates |
| 09/23/2004 | US20040186089 Compounds useful in the treatment of anthrax |
| 09/15/2004 | EP1456393A1 Cyclisation process for the preparation of c-2 beta-lactam compounds |
| 09/15/2004 | EP1395588A4 Process for the isolation of crystalline imipenem |
| 09/15/2004 | EP1395587A4 Process for the preparation of imipenem |
| 09/10/2004 | WO2003027067A3 Process for making carbapenem compounds |
| 09/09/2004 | US20040176351 Process for making carbapenem compounds |
| 09/09/2004 | US20040176350 Carbapenem compound |
| 09/01/2004 | EP1450796A1 Benzothiazole derivatives |
| 08/26/2004 | WO2004072073A1 Crystal of intermediate for carbapenem |
| 08/26/2004 | CA2515741A1 Crystal of synthetic intermediate of carbapenem |
| 08/25/2004 | EP1448563A1 Process for the preparation of crystalline imipenem |
| 08/25/2004 | CN1163494C Carbapenem derivative, use thereof and intermediate compound of the same |
| 08/19/2004 | WO2004069839A1 Carbapenem derivative |
| 08/18/2004 | EP1446009A2 Compounds useful in the treatment of anthrax |
| 08/18/2004 | CN1522255A Process for the isolation of crystalline imipenem |
| 08/12/2004 | WO2004067536A2 Carboxylic acid esters to improve bioavailability of pharmaceutical compounds |
| 08/12/2004 | WO2004067532A1 Novel carbapenem derivatives |
| 08/12/2004 | CA2509793A1 Carboxylic acid esters to improve bioavailability of pharmaceutical compounds |
| 08/04/2004 | EP1443047A1 Novel carbapenem compounds |
| 08/04/2004 | EP1442038A2 Crystalline forms of carbapenem antibiotics and methods of preparation |
| 07/28/2004 | EP0823895B1 Fatty acid esters as bioactive compounds |
| 07/08/2004 | US20040132668 Crystalline 1-methylcarbapenem derivatives |
| 07/07/2004 | CN1511156A 碳青霉烯化合物 Carbapenem compounds |
| 06/23/2004 | CN1154649C Novel C-2 5/0-and S/N formaldehyde acetal derivatives of carbapenem-3-carboxylic acids and their use as antibiotics and beta lactamase inhibitors |
| 06/09/2004 | EP1426376A1 Process for preparation of carbapenem antibiotics |
| 05/27/2004 | WO2004043973A1 Novel intermediate for carbapenem compound for oral administration and process for producing the same |
| 05/27/2004 | WO2004043961A1 Process for producing carbapenem compound for oral administration |
| 05/27/2004 | US20040102433 Bactericides; abtibiotic resistant grampositive bacteria |
| 04/27/2004 | CA2241092C 1-methylcarbapenem derivatives |
| 04/22/2004 | WO2003072015A3 Compounds useful in the treatment of anthrax |
| 04/14/2004 | CN1489589A Novel carbapenem compounds |
| 04/07/2004 | EP1182204B1 Crystals of carbapenem derivatives and pharmaceutical preparations for injection |
| 04/07/2004 | EP1104424B1 Process for the synthesis of carbapenem intermediates |
| 04/01/2004 | US20040063931 Hydrogenolysis using prereduced metal catalyst |
| 04/01/2004 | US20040063683 Novel carbapenem compounds |
| 03/31/2004 | CN1486322A Novel carbapenem derivatives |
| 03/31/2004 | CN1486318A Improved process for carbapenem synthesis |
| 03/31/2004 | CN1486317A 1-methylcarbapenem derivatives |
| 03/31/2004 | CN1486316A Processes for the preparation of carbapenem-type antibacterial agents |
| 03/24/2004 | CN1484645A Novel B-lactam compounds and process for producing the same |
| 03/18/2004 | US20040054167 Process for the preparation of crystalline n-formimidoyl thienamycin monohydrate (imipenem monohydrate) |
| 03/17/2004 | EP1398314A1 Carbapenem compound |
| 03/17/2004 | CN1482122A Intermediates for producing 2-thiosubstituted carbapenems |
| 03/10/2004 | EP1396492A1 Prodrug of an ice inhibitor |
| 03/10/2004 | EP1395588A2 Process for the isolation of crystalline imipenem |
| 03/10/2004 | EP1395587A1 Process for the preparation of imipenem |
| 03/10/2004 | CN1481385A Process for formulation of antibiotic compounds |
| 03/10/2004 | CN1481384A Process for prepn. of crystalline N-forminidoyl thienamycin monohydrate (imipenem monohydrate) |
| 03/03/2004 | EP0906313B1 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
| 02/26/2004 | US20040038967 Novel carbapenem derivatives |
| 02/05/2004 | US20040023290 Novel therapeutic agents that modulate enzymatic processes |
| 01/28/2004 | CN1136208C Intermediate for preparing 2-thiosubstituted carbapenems |
| 01/22/2004 | US20040014962 Such as (1R,5S,6S)-2-(1-(4-carbamoyl-1,3-thiazol-2-yl)azetidin-3-yl)thio-6-((1R)-1 -hydroxyethyl)-1-methylcarbapen -2-em-3-carboxylic acid for treatment/prevention of bacterial infections |
| 01/20/2004 | US6680313 1-hydroxyethyl-2(imidazo(5,1b)thiazol-2-yl-1-carbapen-2-em-3-c carboxylic acid or salt, excellent antibiotic activity against a wide spectrum of bacteria |
| 01/20/2004 | CA2108356C Antibiotic compounds |
| 01/13/2004 | US6677331 Having substituted imidazo(5,1-b)thiazole group at 2-position; microbiocides against beta-lactamase producing bacteria and resistant pseudomonas |
| 12/18/2003 | US20030232803 Crystalline 1-methylcarbapenem derivatives |
| 12/04/2003 | US20030225055 Having a 1-alkylpyrrolidine structure; 5-alkyl-2-thia-5-azabicyclo(2.2.1) heptan-3-ones or salts thereof useful as synthetic intermediates |
| 11/25/2003 | CA2106370C Antibiotic compounds |
| 11/20/2003 | WO2003095454A1 1ß-METHYLCARBAPENEM DERIVATIVE FOR ORAL ADMINISTRATION |
| 11/18/2003 | US6649756 Process improvement in the preparation of (4r, 5s, 6s)-3-[[(2r,3r)-2-[[[(s)-2-amino-3-methyl-1-oxobutyl]amino]methyl]tetrahydro-3-furanyl]thio]-6-[(r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
| 11/12/2003 | EP0991651B1 Stabilized carbapenem intermediates and synthetic use |
| 11/04/2003 | US6642377 Process for the preparation of basic antibiotic-inorganic acid addition salts and intermediate oxalates |
| 10/30/2003 | WO2003089432A1 Process for producing carbapenem derivative |
| 10/30/2003 | WO2003089431A1 Novel carbapenem compounds |
| 10/29/2003 | EP1357123A1 Novel carbapenem compounds |
| 10/22/2003 | EP1353923A1 Improved process for carbapenem synthesis |
| 10/22/2003 | EP0863901B1 Carbapenem antibiotic, composition and method of preparation |
| 10/16/2003 | WO2002094773A3 Process for the isolation of crystalline imipenem |
| 10/15/2003 | EP1351960A1 Improved preparation of (4r, 5s, 6s)-3-[[(2r,3r)-2-[[[(s)-2-amino-3-methyl-1-oxobutyl]methyl]tetrahydro-3-furanyl]thio]-6-[(r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
| 09/18/2003 | US20030176670 Multivalent macrolide antibiotics |