Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
05/2008
05/29/2008WO2008062739A1 Pyrazoles and use thereof as drugs
05/29/2008WO2008062011A1 Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods
05/29/2008WO2008045673A3 Quinolone carboxylic acids, derivatives thereof, processes for its preparation and its use as antibacterial agents
05/29/2008WO2008045564A3 Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
05/29/2008WO2008042928A3 Oxadiazole and thiadiazole derivatives as mitotic kinesin inhibitors and methods of use thereof
05/29/2008WO2008016123A1 GSK-3β INHIBITOR
05/29/2008US20080125587 Synthesis of triazole compounds that modulate HSP90 activity
05/29/2008US20080125436 MgluR5 modulators
05/29/2008US20080125431 E.g., 3-(2'-Morpholin-4-ylmethyl-biphenyl-4-ylmethyl)-1-oxa-3-aza-spiro[4.5]decan-2-one; acute and chronic neurological and psychiatric disorders and chronic and acute pain disorders; Alzheimer's disease; schizophrenia; antidepressants; bipolar disorders; antiischemic agents; cardiotonic agents
05/29/2008US20080125427 Novel Inhibitors of Rho-Kinases
05/29/2008US20080125426 7-(4-Chlorophenyl)-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile; reversible inhibitors of cysteine proteases S, K, F, L, B; diseases associated with Cathepsin S; antiinflammatory agent, autoimmune diseases; asthma, rheumatoid arthritis, multiple sclerosis, Alzheimer's and Crohn's disease
05/29/2008US20080125422 Use of 5ht4 receptor antagonists in the prophylaxis or treatment of certain cardiovascular conditions
05/29/2008US20080125418 Benzimidazole derivatives and their use as kdr kinase protein inhibitors
05/29/2008US20080125416 Sigma Receptor Inhibitors
05/29/2008CA2670404A1 Heteromonocyclic compound and use thereof
05/29/2008CA2670026A1 Heterotricyclic metalloprotease inhibitors
05/29/2008CA2669104A1 Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity
05/29/2008CA2669102A1 Tetralin analogs having sphingosine 1-phosphate agonist activity
05/29/2008CA2668661A1 Substituted pyrazole and triazole compounds as ksp inhibitors
05/29/2008CA2668567A1 Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods
05/28/2008EP1924579A2 Benzooxazole, oxazolopyridine, benzothiazole and thiazolopyridine derivatives
05/28/2008EP1924570A1 Azole and thiazole derivatives and their use
05/28/2008EP1924568A1 Quinazoline derivatives useful in cancer treatment
05/28/2008EP1924566A1 Diaminopyrimidines as p2x3 and p2x2/3 modulators
05/28/2008EP1924564A1 Diaminopyrimidines as p2x3 and p2x2/3 modulators
05/28/2008EP1924561A2 6-arylalkylamino- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
05/28/2008EP1781644B1 Macrocyclic beta-secretase inhibitors
05/28/2008EP1701940B1 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
05/28/2008EP1599471B1 Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents
05/28/2008EP1496898B1 Tyrosine kinase inhibitors
05/28/2008EP1218360B1 Triazine kinase inhibitors
05/28/2008CN101189228A Bicyclic [3.1.0] heteroaryl amides as type I glycine transport inhibitors
05/28/2008CN101189226A Piperidin-4-yl-amide derivatives and their use as SST receptor subtype 5 antagonists
05/28/2008CN101189225A Heteroaryl substituted pyrazinyl-piperazine-piperidines with CXCR3 antagonist activity
05/28/2008CN101189210A Sulfonamide derivatives useful as liver carnitine palmitoyl transferase (L-CPTl) inhibitors
05/28/2008CN100390169C Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents
05/28/2008CN100390168C 2-pyrrolidin-2-yl-[1,3,4]-oxadiazole derivatives and their use as anti-depressants
05/28/2008CN100390157C Substituted benzoxazinones and uses thereof
05/28/2008CN100390156C Novel antibacterial compounds, process for their preparation and pharmaceutical compositions containing them
05/28/2008CN100390149C Indazole derivatives
05/27/2008US7378529 Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4
05/27/2008US7378525 CCR8 inhibitors
05/27/2008US7378524 e.g., 6-chloro-2-methyl-4-(N-(2-(N-(p-methoxyphenylsulfonyl)-N-(2-(2,5-dimethoxy-4-nitroanilinocarbonyl)ethyl)amino)ethyl)amino)quinoline; used to treat inflammatory and immune diseases by binding to CXCR3 receptors.
05/27/2008US7378435 High affinity and selectivity for GABA A alpha 5 receptor binding sites; cognitive enhancer; Alzheimer's disease; 3-(5-methyl-3-phenyl-isoxazole-4-carbonyl)-1H-indole-6-carboxylic acid prop-2-ynylamide
05/27/2008US7378433 N-[4-(heteroarylmethyl)phenyl]-heteroarylamines
05/27/2008US7378423 Antiproliferative, anticancer, antitumor agents; rheumatism; N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]-phenyl}-acetamide; a p15, and/or a protein inducing action, and/or an MEK inhibitory action; side effect reduction
05/27/2008US7378417 Pyrazolo-pyrimidine derivatives
05/27/2008US7378416 3-((C3-8)cycloalkyl)-3,4-dihydro-benzo[e][1,3]oxazin-2-ones; counter-regulator of antiinflammatory effects of glucocorticoids with effect that normal activities of glucocorticoids to limit and suppress severity of inflammatory responses are inhibited by macriphage migration inhibitory factor (MIF)
05/27/2008US7378411 Substituted thienopyrimidinones as a mitotic kinesin inhibitor
05/27/2008US7378409 Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
05/27/2008US7378397 Peptide derivatives; thyrotropin-releasing hormone-degrading; brain and spinal injuries, central nervous system disorders
05/27/2008US7378375 Substituted pyridine herbicides
05/27/2008US7378240 hybridization probe; sequence-recognizing nucleic acid portion and a cyanine dye reporter portion; allows real time monitoring of PCR
05/22/2008WO2008061236A2 Sulfoximines as kinase inhibitors
05/22/2008WO2008060569A1 Compounds and methods for inhibiting the interaction of bcl proteins with binding partners
05/22/2008WO2008059867A1 Novel 1,2-dihydroquinoline derivative having (substituted phenyl or substituted heterocyclic) carbonyloxy lower alkyl group and ester-introduced phenyl group as substituents
05/22/2008WO2008059866A1 Novel 1,2-dihydroquinoline derivative having substituted phenylamino lower alkyl group and ester-introduced phenyl group as substituents
05/22/2008WO2008059865A1 Novel 1,2-dihydroquinoline derivative having substituted phenylchalcogeno lower alkyl group and ester-introduced phenyl group as substituents
05/22/2008WO2008059239A1 Novel compounds 514
05/22/2008WO2008059214A1 Bisamlde derivatives and use thereof as fatty acid synthase inhibitors
05/22/2008WO2008059128A1 Phenylic derivatives and use thereof as drugs
05/22/2008WO2008058867A2 Substituted 4-imidazoles
05/22/2008WO2008058341A1 Inhibitors of kinase activity
05/22/2008WO2008032191A3 Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
05/22/2008WO2008021331A3 Oxazolidone derivatives as pr modulators
05/22/2008WO2008011392A3 Proline urea ccr1 antagonists for the treatment of autoimmune diseases or inflammation
05/22/2008WO2007138431A3 Azabicyclic ether histamine-3 antagonists
05/22/2008WO2007104557A3 Novel heterocyclic nf-kb inhibitors
05/22/2008WO2006055561A3 Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
05/22/2008US20080119648 Histone deacetylase inhibitors
05/22/2008US20080119535 Aminomethyl-4-imidazoles
05/22/2008US20080119531 PPAR gamma agonists or partial agonists; type II diabetes, including hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity; compounds have a thiazolidinedione or an oxazolidinedione substituent
05/22/2008US20080119526 Ep2 receptor agonists
05/22/2008US20080119522 5,6-dichloro-2-(2,2,2-trifluoro-ethyl)-1H-benzimidazole for example; use for prostate cancer, benign prostatic hyperplasia (BPH), hirsutism, alopecia, anorexia nervosa, breast cancer, acne, AIDS, cachexia, as a male contraceptive, and/or as a male performance enhancer
05/22/2008US20080119520 Disorders related to memory and cognition processes, neurological processes, cardiovascular function, and body weight; benzoxazole, benzimidazole, and indole compounds substituted with pyrrole, azepane, piperidine or azetidine e.g. 4-{2-[2-(2-methyl-pyrrolidin-1-yl)-ethyl]-benzooxazol-5-yl}-benzonitrile
05/22/2008US20080119488 Modulators Of Nuclear Receptors
05/22/2008US20080119487 Novel non-imidazole compounds
05/22/2008US20080119478 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria
05/22/2008US20080119476 Cetp Inhibitors
05/22/2008US20080119471 1-((4-chlorophenoxy)methyl)carbonyl-2-methyl-4-(4-fluorobenzyl)piperazine; chemokine receptor CCR1 antagonist; chemokine (MIP-1 alpha and RANTES) inhibitor; antiinflammatory agent; multiple sclerosis, rheumatoid arthritis
05/22/2008US20080119470 8-hydroxy-3H-quinazolin-4-(thi)one derivatives; ability to enter CNS, sequester transition metals Cu, Zn and Fe from various amiloid beta entities, reducing their toxicity; neurodegenerative disorders; Alzheimer's, Parkinson's, Cruetzfeldt-Jacob diseases, amyotrophic lateral sclerosis, cataract
05/22/2008US20080119469 Novel Compounds
05/22/2008US20080119468 Phthalazine, aza-and diaza-phthalazine compounds and methods of use
05/22/2008US20080119466 1-(4-Chloro-3-(trifluoro-methyl)phenyl)-3-(4-imidazo-[4,5-c]pyridin-1-ylphenyl)urea; Raf, a serine-threonine protein kinase inhibitor; Raf/MEK/ERK cascade in proliferation of human cancer cells; anticarcinogenic agent; psoriasis, atherosclerosis, chronic rheumatoid arthritis and diabetes
05/22/2008US20080119465 Novel Indoline Compounds
05/22/2008US20080119464 N-(4-piperidin-1-yl-phenyl)-2-[5-(thiaxolidine-3-carbonyl)-pyrrolidin-3-ylidene]-acetamide;antidiabetic agents; hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis
05/22/2008US20080119457 2-Bromo-4-(1,5,5-trimethyl-7-oxo-4,5,6,7-tetrahydro-1H-indazol-3-yl)-benzonitrile; heat-shock protein 90 inhibitors; anticarcinogenic, antiinflammatory agent, angiogenesis inhibitor, fungicide; arthritis, ischemia, solid tumors, leukemia
05/22/2008US20080119456 [2-benzhydryl-4-(4-chlorophenyl)-thiazol-5-yl]-acetic acid; Chemoattractant Receptor-homologous molecule expressed on T Helper cells type 2 ligand; antiallergen and antiinflammatory agent; asthma, rhinitis, allergic airway syndrome, allergic rhinobronchitis; Alzheimer's disease, rheumatoid arthritis
05/22/2008US20080119419 Bifunctional heterocyclic compounds and methods of making and using same
05/22/2008CA2701959A1 Inhibitors of kinase activity
05/22/2008CA2669704A1 Sulfoximines as kinase inhibitors
05/22/2008CA2669607A1 Novel 1,2-dihydroquinoline derivative having (substituted phenyl or substituted heterocyclic) carbonyloxy lower alkyl group and ester-introduced phenyl group as substituents
05/22/2008CA2669596A1 Compounds and methods for inhibiting the interaction of bcl proteins with binding partners
05/22/2008CA2669112A1 Substituted 4-imidazoles
05/22/2008CA2668596A1 Novel 1,2-dihydroquinoline derivative having substituted phenylamino lower alkyl group and ester-introduced phenyl group as substituents
05/22/2008CA2668592A1 Novel 1,2-dihydroquinoline derivative having substituted phenylchalcogeno lower alkyl group and ester-introduced phenyl group as substituents
05/21/2008EP1923391A1 Substituted heterocyclic compounds, method for preparing same and pharmaceutical compositions containing them.
05/21/2008EP1923390A1 Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
05/21/2008EP1922313A1 Pyrazine derivatives useful as adenosine receptor antagonists
05/21/2008EP1756095B1 Cyanopyrrole containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same