Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
08/2008
08/06/2008EP1951674A1 Sulfonamide derivatives and use thereof for the modulation of metalloproteinases
08/06/2008EP1660491B1 Benzimidazole, benzthiazole and benzoxazole derivatives and their use as lta4h modulators
08/06/2008EP1651621B1 2- (quinoxalin-5-ylsulfonylamino) -benzamide compounds as cck2 modulators
08/06/2008EP1397341B1 6-(aryl-amido or aryl-amidomethyl)-naphthalen-2-yloxy-acidic derivatives as inhibitors of plasminogen activator inhibitor type-1 (pai-1)
08/06/2008CN101238120A Urea derivatives methods for their manufacture and uses thereof
08/06/2008CN101238118A Salts and polymorphs of a VEGF-R inhibitor
08/06/2008CN101238106A Fluoro substituted 2-oxo azepan derivatives
08/06/2008CN101235131A Method for preparing benzoxazine intermediate containing propargyl ether and resin thereof
08/06/2008CN101235033A Benzoxazine containing maleimide and allyl ether, and preparation method thereof
08/06/2008CN100408573C Pyrazole compounds useful as protein kinase inhibitors
08/06/2008CN100408570C EP4 receptor antagonists
08/06/2008CN100408564C Pyrazole derivatives for treating HIV
08/05/2008US7408067 Neuregulins such as 4-(4-Hydroxyphenylthio)-piperidine trifluoroacetate for treatment of dysfunctions of central and autonomic nervous systems
08/05/2008US7408065 P2X7 receptor antagonists and their use
08/05/2008US7408063 1,8-annelated quinoline derivatives substituted with carbon-linked triazoles as farnesyl transferase inhibitors
08/05/2008US7407974 e.g. 4-Methoxy-pyrrolidine-1,2-dicarboxylic acid 1-[(4-chloro-phenyl)-amide] 2-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide}; anticoagulant, thrombolytic agent; thrombus formation within blood vessels; cardiovascular disease
08/05/2008US7407972 e.g. 4,5-Dihydro-pyrazole-1,5-dicarboxylic acid 1-[(4-chloro-phenyl)-amide] 5-[(3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-amide]; anticoagulant, thrombolytic agent; thrombus formation within blood vessels; cardiovascular disease
08/05/2008US7407969 e.g. N-[1-(2-aminoethyl)-4-piperidinyl]-7-methyl-3-(8-quinolinylmethyl)-3H-imidazo[4,5-b]pyridin-2-amine tetrahydrochloride trihydrate; immunostimulant; lower respiratory tract illness during infancy and childhood, asthma, pneumonia
08/05/2008US7407968 Compounds
08/05/2008US7407961 Adenosine antagonists; depression, dementia (e.g. Alzheimer's disease), Parkinson's disease, anxiety, pain, cerebrovascular disorders, heart failure, hypertension, edema, obesity, bronchial asthma
08/05/2008US7407960 e.g. 2-{4-[(2R)-2-hydroxy-3-(2-methylbenzothiazol-5-yloxy)propyl]piperazinyl}-N-((1S)-1-phenylethyl)acetamide; fatty acid oxidation inhibitor; cardiovascular diseases: atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's angina, stable and unstable angina, and diabetes
08/05/2008US7407950 N-(heteroaryl)-1H-indole-2-carboxamide derivatives and their use as vanilloid TRPV1 receptor ligands
08/05/2008CA2417081C New n, n'-disubstituted benzimidazolone derivatives with affinity at the serotonin and dopamine receptors
08/05/2008CA2314514C Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents
08/05/2008CA2293358C Tricyclic sulfonamide inhibitors of farnesyl-protein transferase
08/05/2008CA2279319C Benzofurazan compounds which enhance ampa receptor activity
08/05/2008CA2176649C 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones
07/2008
07/31/2008WO2008091752A2 Quinolone carboxylic acids, derivatives thereof, processes for their preparation and their use as antibacterial agents
07/31/2008WO2008091580A2 Fungicidal amides
07/31/2008WO2008091021A1 Heterocyclidene-n-(aryl)acetamide derivative
07/31/2008WO2008090570A1 Novel antimicrobials
07/31/2008WO2008090382A1 Thiazole and oxazole derivatives for use in the treatment of prion diseases, cancer and conditions of the central nervous system as well as in the regulation of stem cells
07/31/2008WO2008090357A2 N, n; -substituted piperazines binding to melanocortin receptor
07/31/2008WO2008090046A1 Alternate process for preparing 3,5-di-omicron-acyl-2-fluoro-2-c-methyl-d-ribono-gamma-lactone
07/31/2008WO2008089933A2 Benzoquinazole derivatives
07/31/2008WO2008073687A3 Compounds and compositions as protein kinase inhibitors
07/31/2008WO2008061236A3 Sulfoximines as kinase inhibitors
07/31/2008WO2008011557A3 Heteroaryl inhibitors of rho kinase
07/31/2008WO2007077201A9 Piperazine compounds with a herbicidal action
07/31/2008US20080182879 e.g. 6-hydroxy-2-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]chromone; tyrosine kinase inhibitors, anticarcinogenic and antiinflammatory agent; cerebral, genito-urinary tract, lymphatic system, stomach, laryngeal, pancreatic, breast or lung tumor; rheumatoid arthritis, psoriasis, contact dermatitis
07/31/2008US20080182874 e.g. 1-[6-Chloro-5-[(tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]-2-quinolinyl]-4piperidinecarboxylic acid; adamantyl-containing purinergic receptor P2X7 antagonists; antiinflammatory agent, immune or cardiovascular diseases; asthma, chronic obstructive pulmonary disease, rheumatoid arthritis
07/31/2008US20080182860 Pyrimidine Compounds as Purine Receptor Antagonist
07/31/2008US20080182854 4-Amino-5-Cyanopyrimidine Derivatives
07/31/2008US20080182850 3-(heteroaryl)alanine derivatives-inhibitors of leukocyte adhesion mediated by vla-4
07/31/2008US20080182845 Method of preventing or treating organ, hematopoietic stem cell or bone marrow transplant rejection
07/31/2008US20080182843 Mitotic Kinesin Inhibitors
07/31/2008US20080182840 Inhibitors of the FAK (focal adhesion kinase) protein tyrosine kinases, antiproliferative, antitumor; for example 5-{4-[(1-Hydroxy-cyclopentylmethyl)-amino]-5-trifluoromethyl-pyrimidin-2-ylamino}-1,3-dihydro-indol-2-one
07/31/2008US20080182302 Open reading frames which encode polypeptides sufficient to direct the biosynthesis synthesis of a safracin molecule having improved properties and that could be used in the hemi-synthesis of new ecteinascidins compounds; combinatorial chemistry; antitumor agents; broad-spectrum antibiotics; bactericides
07/31/2008CA2676020A1 Heterocyclidene-n-(aryl) acetamide derivative
07/31/2008CA2674921A1 Benzoquinazoline derivatives
07/30/2008EP1950206A1 Benzoxazocines and their use as monoamine-reuptake inhibitors
07/30/2008EP1950201A1 Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors
07/30/2008EP1950199A1 Proline derivatives and use thereof as drugs
07/30/2008EP1948649A2 Fungicidal carboxamides
07/30/2008EP1948648A2 3-aryl-isoxazole-4-carbonyl-benzofuran derivatives
07/30/2008EP1948645A1 Tricyclo substituted amides
07/30/2008EP1948644A1 Tricyclo substituted amides
07/30/2008EP1948639A2 Novel carbocyclic fused cyclic amines
07/30/2008EP1948629A1 Substituted piperazines and piperidines as modulators of the neuropeptide y2 receptor
07/30/2008EP1948624A2 Process for the preparation of benzo[e][1,2,4]triazepin-2-one derivatives
07/30/2008EP1948616A1 2-(benzimidazol-1-yl)-acetamide biaryl derivatives and their use as inhibitors of the trpv1 receptor
07/30/2008EP1948605A2 Modulators of the h3 receptor useful for the treatment of disorders related thereto
07/30/2008EP1948193A2 Aminopyrimidines useful as kinase inhibitors
07/30/2008EP1737462B1 Pyrimidines with tie2 (tek) activity
07/30/2008EP1660447B1 Cyclic amine bace-1 inhibitors having a heterocyclic substituent
07/30/2008EP1633729B1 Sulphonamide compounds that modulate chemokine receptor activity (ccr4)
07/30/2008EP1531817B1 Glycinamide derivatives as raf-kinase inhibitors
07/30/2008CN101233130A Diazine azole derivatives, their manufacture and use as pharmaceutical agents
07/30/2008CN101233129A Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases
07/30/2008CN101233128A Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes
07/30/2008CN101233119A Novel heterocyclic nf-kb inhibitors
07/30/2008CN101230060A Substitutional piperidines
07/30/2008CN101230038A Pyridine carboxamide derivatives and their use as pesticides
07/30/2008CN101230008A Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
07/30/2008CN100406454C Pyrazole compounds useful as protein kinase inhibitors.
07/30/2008CN100406453C 4-anilino-quinazoline derivatives as antiproliferative agents
07/30/2008CN100406446C Benzoxazole derivatives and their use as adenosine receptor ligands
07/30/2008CN100406439C Pyrrolidine derivatives as metalloprotease inhibitors
07/29/2008US7405310 Non-nucleoside reverse transcriptase inhibitors
07/29/2008US7405295 Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
07/29/2008US7405231 Oxidized thioether derivatives
07/29/2008US7405228 Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites
07/29/2008US7405217 N-aroyl piperazine derivatives as orexin receptor antagonists
07/29/2008US7405216 Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
07/29/2008US7405215 e.g. [3-(3-benzyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-indol-1-yl]-acetic acid; inhibit binding of endogenous ligands, including prostaglandin PGD2 and its metabolites and certain thromboxane metabolites (such as 11-dehydro-TXB2), to CRTH2; antiallergent; asthma, bronchitis, rhinitis, cough, psoriasis
07/29/2008US7405211 Therapeutic morpholino-substituted compounds
07/29/2008US7405209 Protease inhibitors
07/29/2008CA2432222C Pyrazole compounds useful as protein kinase inhibitors
07/29/2008CA2432132C Pyrazole compounds useful as protein kinase inhibitors
07/29/2008CA2401033C 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
07/29/2008CA2382322C Aminocarbonyl-substituted benzimidazole derivatives, processes for preparing them and their use as pharmaceutical compositions
07/29/2008CA2333008C New heterocyclically substituted amides, their production and their use
07/29/2008CA2262997C Pharmaceutical products for curing and preventing illnesses connected with the malfunction of vascular endothelial cells
07/29/2008CA2256022C 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission
07/29/2008CA2175767C Adhesion receptor antagonists
07/24/2008WO2008089005A2 Renin inhibitors
07/24/2008WO2008087936A1 Condensed tetrahydroquinoline derivative and use thereof for medical purposes
07/24/2008WO2008087529A1 Nicotinic acetylcholine receptor modulators
07/24/2008WO2008087383A1 Purification process comprising dissolving an organic compound in carbonated water and freeze-drying
07/24/2008WO2008087178A1 Novel 1,4- and 1,5-diarylsubstituted 1,2,3-triazoles useful as potassium channel modulators