Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
02/2008
02/21/2008US20080045706 Modulating activation state of p38 kinase protein; utilizing compounds with switch control ligands to induce or restrict conformation
02/21/2008US20080045705 2-oxoethyl(1R)-4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-[[3,5-dimethyl-4-(phenylmethoxy)phenyl]methyl]-2-[4-(4-morpholinyl)-1-piperidinyl]-1-piperidinecarboxylate; coupling alpha -hydroxy-3,5-dimethyl-4-(phenylmethoxy)-phenylpropionic acid-monosodium salt with 1,3-benzodiazepin compound
02/21/2008US20080045620 Piperazino Based Photoinitiators
02/21/2008US20080045580 Novel Isoxazole Compounds Having Ppar Agonist Activity
02/21/2008US20080045579 Oxazolidine derivatives as PR modulators
02/21/2008US20080045576 Therapeutic n-aryl or n-heteroaryl pyrazolidine and pyrazolidinone derivatives
02/21/2008US20080045571 Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
02/21/2008US20080045569 Cyclic Amine Compound and Pest Control Agent
02/21/2008US20080045561 protein kinase inhibitors such as 5,6-Dimethoxy-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-pyrrolo[3,2-b]pyridine, used for the treatment of cancer
02/21/2008US20080045560 Pyrrolidine and related derivatives useful as PR modulators
02/21/2008US20080045556 4-[2-(4,4-Dimethyl-2-thioxo-1,3-oxazolidin-3-yl)-1,3-thiazol-4-yl]benzonitrile; progesterone receptor (PR); contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, hormone replacement therapy
02/21/2008US20080045540 Sulfonyl pyrrolidines, method for producing the same and their use as drugs
02/21/2008US20080045528 6-o-substituted benzoxazole and benzothiazole compounds and methods of inhibiting csf-1r signaling
02/21/2008US20080045525 Piperazinyl-Pyridine Analogues
02/21/2008US20080045524 Selective NPY (Y5) antagonists
02/21/2008US20080045523 Synthesis of Polyoxygenated Nitrogen Systems, Comprising Reactions Between Enamines of 1,3-Dioxan-5-Ones and Nitroolefins
02/21/2008US20080045518 3-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-4-methyl-1,3-oxazolidin-2-one; alternative progesterone receptor modulator; contraception, fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, hormone replacement therapy, eating disorder, synchronizing estrus
02/21/2008US20080045516 Viral Polymerase Inhibitors
02/21/2008US20080045509 Substituted benzyl amine compounds
02/21/2008US20080045506 Pyrrolidine Derivatives as Histamine Receptors Ligands
02/21/2008US20080045505 1-(isopropyl)-4-{[4-(tetrahydro-2H-pyran4-yloxy)phenyl]carbonyl}hexahydro-1H-1,4-diazepine, used in the treatment of nervous system and psychological disorders such as Alzheimer's disease or as cognition activators
02/21/2008US20080045503 Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
02/21/2008US20080045493 such as Parkinson's disease, schizophrenia, cognitive disorders, depression, anxiety, drug addiction, eating disorders and urogenital disorders; 4-(2,2-Difluoro-cyclopropyl)-N-[4-(1-propyl-piperidin-3-yl)-phenyl]-benzenesulfonamide
02/21/2008US20080045489 3,4-di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands
02/21/2008US20080044881 Advanced Indolinone Based Protein Kinase Inhibitors
02/21/2008US20080044401 Drug therapy for celiac sprue
02/21/2008US20080044355 including cystic fibrosis transmembrane conductance regulator ("CFTR"); amido-phenyl derivatives; genetic disorders; respiratory system disorders, cystic fibrosis, hereditary emphysema, hereditary hemochromatosis, coagulation-fibrinolysis and lipid processing deficiencies, lysosomal storage disease
02/21/2008CA2661093A1 Dicer substrate rna peptide conjugates and methods for rna therapeutics
02/21/2008CA2660736A1 Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives
02/21/2008CA2660703A1 Salts of 5-(1(s)-amino-2-hydroxyethyl)-n-[(2,4-difluorophenyl)-methyl]-2-[8-methoxy-2-(trifluoromethyl)-5-quinoline]-4-oxazolecarboxamide
02/21/2008CA2660576A1 Insecticidal isoxazolines
02/21/2008CA2660560A1 Pyrazine compounds, their use and methods of preparation
02/21/2008CA2660555A1 Viral polymerase inhibitors
02/21/2008CA2659208A1 Oxazolidone derivatives as pr modulators
02/21/2008CA2658960A1 Phenyl, pyridine and quinoline derivatives
02/21/2008CA2650932A1 Substituted spirocyclic cgrp receptor antagonists
02/20/2008EP1889845A1 Novel pleuromutilin derivatives
02/20/2008EP1889843A1 Bisheterocycle tandem compounds useful as antiviral agents, the uses thereof and the compositions comprising such compounds
02/20/2008EP1888574A2 New antibiotic derivatives
02/20/2008EP1888572A1 Quinazolines and their use as aurora kinase inhibitors
02/20/2008EP1888571A2 New salt and polymorphs of a dpp-iv inhibitor
02/20/2008EP1888570A2 Methods for synthesis of dicarbamate compounds and intermediates in the formation thereof
02/20/2008EP1888569A1 Substituted piperidines as renin inhibitors
02/20/2008EP1888567A1 Heteroaryl-carboxylic acid (sulfamoyl alkyl) amide - derivatives as factor xa inhibitors
02/20/2008EP1888562A2 Dipeptidyl peptidase-iv inhibitors
02/20/2008EP1888559A2 Piperazine-piperidine antagonists and agonists of the 5-ht1a receptor
02/20/2008EP1888543A1 Apoptosis promoters
02/20/2008EP1888542A1 Substituted spiro-compounds and the use thereof for producing medicaments
02/20/2008EP1888541A1 Benzo(d)isoxazol-3-yl-amine compounds and their use as vanilloid receptor ligands
02/20/2008EP1888538A1 (3,4-dihydro-quinazolin-2-yl)-(2-aryloxy-ethyl)-amines having an activity on the 5-ht receptor
02/20/2008EP1888530A2 Quinoline derivatives as neurokinin receptor antagonists
02/20/2008EP1888528A2 Phosphodiesterase 4 inhibitors
02/20/2008EP1888517A1 Novel 8-sulfonylamino-3 aminosubstituted chroman or tetrahydronaphtalene derivatives modulating the 5ht6 receptor
02/20/2008EP1888512A2 Chemical compounds
02/20/2008EP1558247B1 Benzimidazole derivatives
02/20/2008EP1448561B1 Beta 3 adrenergic agonists
02/20/2008EP1432417B1 Substituted benzimidazole compounds and their use for the treatment of cancer
02/20/2008EP1175411B1 Cyclothiocarbamate derivatives as progesterone receptor modulators
02/20/2008CN101128460A Tricyclic delta-opioid modulators
02/20/2008CN101128459A Isoxazoline derivative and novel process for its preparation
02/20/2008CN101128458A Tricyclic delta-opioid modulators
02/20/2008CN101128457A 凝血酶受体拮抗剂 Thrombin receptor antagonists
02/20/2008CN101128441A Fused aromatic compounds having anti-diabetic activity
02/20/2008CN101128434A Amide derivatives
02/20/2008CN101128432A Tetrahydroisoquinoline compounds for treatment of cns disorders
02/20/2008CN101128430A Pyridine compounds for the treatment of prostaglandin mediated diseases
02/20/2008CN101128413A Substituted oxyarenes
02/20/2008CN101125138A Inhibitors against the production and release of inflammatory cytokines
02/20/2008CN100369899C Substituted indazoles with anti-cancer activity
02/20/2008CN100369888C N-alkanoylphenylalanine derivatives
02/19/2008US7332602 Pyridyl substituted heterocycles useful for treating or preventing HCV infection
02/19/2008US7332515 Indole-amid derivatives which possess glycogen phosphorylase inhibitory activity
02/19/2008US7332512 Halogenated nitrobutadienes for controlling animal pests
02/19/2008US7332511 Vanilloid receptor ligands and their use in treatments
02/19/2008US7332500 Heterocyclic antiviral compounds
02/19/2008US7332493 [3-Methyl-4-(pyridin-3-yloxy)-phenyl]-(6-piperidin-3-ylethynyl-quinazolin-4-yl)-amine; selective inhibitors of receptor tyrosine kinases and non-receptor tyrosine kinases (eg: Ick, src, abl) or serine/threonine kinases (e.g.: cyclin dependent kinases); carcinoma
02/19/2008US7332492 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor
02/19/2008US7332490 inhibit smooth muscle cell proliferation by modulating Heparan Sulfate Proteoglycans (HSPGs); inhibit or block glycated protein and Advanced Glycation Endproducts (AGE) produced induction of the signaling-associated inflammatory response in endothelial cells; antiproliferative and antiinflammatory agent
02/19/2008US7332489 Methods and compositions of novel triazine compounds
02/19/2008US7332488 Methods and compositions of novel triazine compounds
02/19/2008US7332487 Nitrogen-containing 5-membered ring compound
02/19/2008US7332484 2,4-pyrimidinediamine compounds and their uses
02/19/2008US7332483 3-(5-benzamido-2-chlorophenyl)-7-methoxy-3,4-dihydroquinazolin-4-one;cytokines (tumor necrosis factor and interleukins) inhibitor; antiinflammatory agent, rheumatoid arthritis, osteoarthritis, psoriasis, chronic obstructive pulmonary disease
02/19/2008US7332477 Visible light and ultraviolet (UV) light sensitive composition for DNA transfer comprising an acid sensitive gene transfer agent, a photoacid generator, and a bioactive agent
02/19/2008US7332354 bioconjugation; luciferins; biopolymer labels
02/19/2008US7332105 Stabilizer mixture comprising specific compounds of the 2,4-bis-(4-phenylphenyl)-6-(2-hydroxyphenyl)-1,3,5-triazine class and selected other UV absorbers as protectants against damage by light, heat and oxygen
02/14/2008WO2008019096A1 Processes for the preparation of n-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)amino}sulfonyl}-2-thiophenecarboxamide
02/14/2008WO2008019074A1 Processes for the preparation of 4-chloro-3-methyl-5-(2-(2-(6-methylbenzo[d][1,3]dioxol-5-yl)acetyl)-3-thienylsulfonamido) isoxazole
02/14/2008WO2008019072A2 Polymorphs of n-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)-amino]sulfonyl}-2-thiophene-carboxamide
02/14/2008WO2008018639A2 Glycine transporter inhibitor
02/14/2008WO2008018090A2 An improved process for the preparation of zolmitriptan
02/14/2008WO2008017852A1 Diamine-containing, tetra- substituted piperazine compounds as melanocortin receptor modulators
02/14/2008WO2008017710A1 1h-quinolin-4-one compounds, with affinity for the gaba receptor, processes, uses and compositions
02/14/2008WO2008017685A1 Nitrate esters of piperidines
02/14/2008WO2008017638A1 Single enantiomer beta-agonists, methods for the production thereof and the use thereof as medication
02/14/2008WO2008017361A2 2-(heterocyclylbenzyl)pyridazinone derivatives
02/14/2008WO2008002570A3 Human protein tyrosine phosphatase inhibitors and methods of use
02/14/2008WO2008000950A3 Derivatives of ureas of piperidine or pyrrolidine, their preparation and their therapeutical use
02/14/2008WO2007136302A3 Active substances, pharmaceutical composition and a method for the production and use thereof
02/14/2008US20080039662 Isomerizing an alkyl cis-4-(alkylsulfonylamino)cyclohexanecarboxylate to form the trans isomer with a base (alkali metal lower alkoxide, hydride or amide) in an aprotic solvent (toluene); forming the free acid by hydrolysis; sulfonation of alkyl 4-aminocyclohexanecarboxylate with alkylsulfinyl chloride