| Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687) |
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| 07/24/2008 | WO2008086854A1 5-([1,3,4] oxadiazol-2-yl)-1h-indazol and 5-([1,3,4] thiadiazol-2-yl)-1h-indazol derivatives as sgk inhibitors for the treatment of diabetes |
| 07/24/2008 | WO2008056259A3 Oxazole derivatives as positive allosteric modulators of metabotropic glutamate receptors |
| 07/24/2008 | WO2008049047A3 Quinoline compounds |
| 07/24/2008 | WO2008024497A3 INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE TYPE 1 |
| 07/24/2008 | WO2008011392A8 Proline urea ccr1 antagonists for the treatment of autoimmune diseases or inflammation |
| 07/24/2008 | US20080177082 N3 alkylated benzimidazole derivatives as mek inhibitors |
| 07/24/2008 | US20080177080 Oxazole derivatives of tetracyclines |
| 07/24/2008 | US20080177067 Crystal forms of 9-hydroxy-risperidone (paliperidone) |
| 07/24/2008 | US20080177066 reacting 2-chloro-sustituted pteridinones with para-aminobenzamides in the presence of acid catalysts, to form pteridinone derivatives having antiproliferative activity |
| 07/24/2008 | US20080176922 Uses of 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssris |
| 07/24/2008 | US20080176917 Schizophrenia; bioavailability, solubility, brain penetrancy; in vivo half life; synthesis; such as 3-[3-({4-methyl-5-[4-(pentafluoro-6-sulfanyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane |
| 07/24/2008 | US20080176911 2-{2-[2-hydroxy(3-methyl)butyrylamino]pentanoyl}amino-5-(1-methylethyl-4-(3-phenyl-1,2,4-oxadiazol-5-yl)thiazole; neurodegenerative diseases: senile dementia, Alzheimer's and Parkinson's diseases, Down's syndrome, amyloid angiopathy, cerebrovascular disorders, Pick's disease, post-traumatic dementias |
| 07/24/2008 | US20080176906 excellent androgen receptor antagonism, excellent pharmacokinetics; low toxicity; anticarcinogenic agents; 1-{[6-Chloro-5-(hydroxymethyl)pyridin-3-yl]methyl}-4-(4-cyanophenyl)-2,5-dimethyl-1H-pyrrole-3-carbonitrile |
| 07/24/2008 | US20080176899 Such as 1-Benzo[1,3]dioxol-5-yl-cyclopropanecarboxylic acid [5-(2-methoxy-pyridin-3-ylmethyl)-thiazol-2-yl]-amide 5-(2-Methoxy-pyridin-3-ylmethyl)-thiazol-2-ylamine; cystic fibrosis transmembrane conductance regulator disorders |
| 07/24/2008 | US20080176864 [4-(3-Methoxy-phenyl)-4-oxo-butyl]-carbamic acid tert-butyl ester; Age related functional decline, osteoporosis, osteopenia, bone fractures, male and female sexual dysfunction, erectile dysfunction, depression, prostate cancer, decreased cognitive ability, or lethargy |
| 07/24/2008 | US20080176863 Capped pyrazinoylguanidine sodium channel blockers |
| 07/24/2008 | US20080176853 Triazine derivatives and their therapeutical applications |
| 07/24/2008 | US20080176850 able to inhibit various mutated RTs, including K103N, Y181C and Y188L |
| 07/24/2008 | US20080176849 e.g. N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]-amino]methyl]phenyl]-2E-2-propenamide; histone deacetylase inhibitor; anticarcinogenic, antitumor, antiproliferative agents; improved stability |
| 07/24/2008 | US20080176848 e.g. N-Hydroxy-3-{1-[4-(1-methyl-1H-indol-5-yl)-benzenesulfonyl]-1H-pyrrol-3-yl}-acrylamide; antiproliferative, anticarcinogenic, antiinflammatory, neuroleptic agent, autoimmune disorders |
| 07/24/2008 | US20080176847 Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| 07/24/2008 | US20080176842 N1-[1-[N-(2-methylpropyl)-N-(phenylsulfonyl)amino]-2R-hydroxy-3S-(phenylmethyl)prop-3-yl]-3-(1-morpholinosulfonyl)-2R-methylpropionamide; viricide; human T-cell leukemia/limphoma virus |
| 07/24/2008 | US20080176840 e.g. 4-(4-(6-(N-(2-methoxyethyl)-N-methylamino)pyridin-3-yl)-5-hydroxy-4H-1,2,4-triazol-3-yl)-6-isopropylbenzene-1,3-diol; Heat Shock Protein 90 (HSP90) modulator; antiproliferative, anticarcinogenic, antiinflammatory agent; angiogenesis inhibition, infections |
| 07/24/2008 | DE102007002717A1 Heterocyclische Indazolderivate Heterocyclic indazole derivatives |
| 07/24/2008 | CA2675735A1 5-(1,3,4-oxadiazol-2-yl)-1h-indazole and 5-(1,3,4-thiadiazol-2-yl)-1h-indazole derivatives as sgk inhibitors for the treatment of diabetes |
| 07/24/2008 | CA2675676A1 Nicotinic acetylcholine receptor modulators |
| 07/23/2008 | EP1947093A1 Substituted morpholine and thiomorpholine derivatives |
| 07/23/2008 | EP1947086A1 Benzene derivative or salt thereof |
| 07/23/2008 | EP1945634A1 Phenylenebisoxazolidine derivatives and their use as anticoagulants |
| 07/23/2008 | EP1945633A1 Compounds and compositions as ppar modulators |
| 07/23/2008 | EP1945630A2 Pyrazine derivatives as sodium channel modulators for the treatment of pain |
| 07/23/2008 | EP1945617A2 Histone deacetylase inhibitors with aryl-pyrazolyl motifs |
| 07/23/2008 | EP1945616A1 Cinnoline compounds as inhibitors of phosphodiesterase type iv (pde4) |
| 07/23/2008 | EP1945609A2 Amino acid derivatives as histone deacetylase (hdac) inhibitors |
| 07/23/2008 | EP1827427B1 Aryloxyethylamine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition |
| 07/23/2008 | EP1761525B1 Thioether derivatives, their manufacture and use as pharmaceutical agents |
| 07/23/2008 | EP1671949B1 Substituted Pyridinylamines |
| 07/23/2008 | EP1615909B1 Piperazine derivatives and their use for the treatment of neurological and psychiatric diseases |
| 07/23/2008 | EP1597247B1 Substituted 3-(benzoylureido)-thiophene derivatives, method for the production and use thereof |
| 07/23/2008 | EP1567489B1 Pyrrolidin-2-one derivatives as inhibitors of thrombin and factor xa |
| 07/23/2008 | EP1382603B1 Nitrogenous fused-ring compound having pyrazolyl group as substituent and medicinal composition thereof |
| 07/23/2008 | EP1218369B1 INHIBITORS OF c-JUN N-TERMINAL KINASES (JNK) AND OTHER PROTEIN KINASES |
| 07/23/2008 | EP1073638B1 Heterocyclically substituted amides, their production and their use |
| 07/23/2008 | EP1071680B1 N,n-disubstituted amides that inhibit the binding of integrins to their receptors |
| 07/23/2008 | CN101228207A Thermosetting compound, composition containing the same, and molding |
| 07/23/2008 | CN101228156A Fungicidal carboxamides |
| 07/23/2008 | CN101228155A Substituted oxadiazole derivatives as positive allosteric modulators of metabotropic glutamate receptors |
| 07/23/2008 | CN101228154A Novel tetracyclic tetrahydrofuran derivatives containing a cyclic amine side chain |
| 07/23/2008 | CN101228152A N-(heteroaryl)-1-heteroarylalkyl-1h-indole-2-carboxamide derivatives, preparation and therapeutic use thereof |
| 07/23/2008 | CN101228140A Imidazole-amino acid derivatives and related compounds synthetic method |
| 07/23/2008 | CN101228139A Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics |
| 07/23/2008 | CN101228134A Substituted arylpyrazoles as antiparasitic agent |
| 07/23/2008 | CN101225085A Phenyl urazan nitrogen nitric oxide donor 2-aniline pyrimidine derivatives, preparation method, compound containing the same and use thereof |
| 07/23/2008 | CN100404544C 9-ketospinosyn derivatives |
| 07/23/2008 | CN100404540C Thiazolo-, oxazalo and imidazolo-quinazoline compounds capable of inhibiting prot ein kinases |
| 07/23/2008 | CN100404532C Substituted diketopiperazines and their use as oxytocyn antagonists |
| 07/23/2008 | CN100404517C Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof |
| 07/23/2008 | CN100404508C Tetrahydroquinoline derivatives |
| 07/23/2008 | CN100404505C Novel substituted indoles |
| 07/22/2008 | US7402696 exert an ACC activity-inhibiting effect that is effective in the treatment of obesity, hyperlipemia, fatty liver, hyperglycemia, impaired glucose tolerance, diabetes, diabetic complications (diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, and diabetic macroangiopathy, hyperten |
| 07/22/2008 | US7402676 Substituted dihydro 3-halo-1H-pyrazole-5-carboxylates their preparation and use |
| 07/22/2008 | US7402606 Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss |
| 07/22/2008 | US7402605 E.g., 17,17-propano-16-hydroxy-5-(4-ethoxycarbonylthiazol-2-yl)-9-oxo-1,2,3,4,20-pentanor-5-thia-8-azaprost-13-ene; EP2 and/or EP4 receptor agonist; immune disease; antiallergens; alopecia; dysmenorrhea; erectile dysfuncction; antiarthritic agents; liver, respiratory, vascular, urogenital disorder |
| 07/22/2008 | US7402604 4-oxy- or amino-substituted indole-2-carboxy acids, esters and amides, e.g., N-(2-hydroxy-1-phenylethyl) 4-hydroxy-1-methyl-1H-indole-2-carboxamide; nicotinic receptor agonist; conditions associated with reductions in nicotinic transmission; Alzheimer's disease, anxiety or schizophrenia |
| 07/22/2008 | US7402597 e.g. [[7-Allyl-3-[2-[2-(2,4-dichlorophenyl)-5-isopropyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yl]oxy]acetic acid; with vehicles (lactose, D-mannitol, glucose), disintegrators (starch or carboxymethylcellulose calcium ), binders (hydroxypropylcellulose) and lubricants (magnesium stearate or talc) |
| 07/22/2008 | US7402583 Substituted quinolines as antitumor agents |
| 07/22/2008 | US7402581 3,5-Dibromo-N-[(2S)-2-(4-fluorophenyl)-4-(3-morpholin-4-ylazetidin-1-yl)butyl]-N-methylbenzamide; neurokinin 1 and 2 (NK1,2) receptors, antagonist; improved pharmacokinetics: not inhibit liver enzyme cytochrome P450, prevent drug-drug interactions, oral bioavailability, antiinflammatory and analgesic |
| 07/22/2008 | US7402579 Quinobenzoxazine analogs and compositions |
| 07/22/2008 | US7402548 Benzoxazole compounds, process for producing the same and herbicides |
| 07/22/2008 | CA2481246C Compounds that modulate ppar activity and methods for their preparation |
| 07/22/2008 | CA2474511C Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders |
| 07/22/2008 | CA2372840C Substituted bicyclic compounds |
| 07/17/2008 | WO2008086404A1 5-pyridinone substituted indazoles |
| 07/17/2008 | WO2008086188A2 Thiophene carboxamides as factor xa inhibitors |
| 07/17/2008 | WO2008086122A2 Imidazole derivatives as kinesin spindle protein inhibitors (eg-5) |
| 07/17/2008 | WO2008085316A1 Bipiperidinyl compounds, compositions containing such compounds and methods of treatment |
| 07/17/2008 | WO2008085008A1 T-cell inhibiting compounds and their use for the treatment of t-cell-mediated diseases |
| 07/17/2008 | WO2008084218A1 Benzazole derivatives for the treatment of inflammations |
| 07/17/2008 | WO2008063625A3 Pyridine compounds and methods of their use |
| 07/17/2008 | WO2008056257A3 Novel triazinedione derivatives as gaba-b receptor modulators |
| 07/17/2008 | WO2008050101A3 Benzoyl amino heterocyclyl compounds useful in the treatment of a disease mediated through glk |
| 07/17/2008 | WO2008045564A8 Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor |
| 07/17/2008 | WO2007092961A3 Antibacterial agents |
| 07/17/2008 | US20080171880 N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N-(4-{4-[3-(1H-tetrazol-5-yl)propoxy]phenyl}butyl)guanidine hydrochloride; absorbed less rapidly from mucosal surfaces, less reversible |
| 07/17/2008 | US20080171874 Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines |
| 07/17/2008 | US20080171872 Ammonium, hydrate, diethylamine, dibenzylamine, piperazine, morpholine salts of atorvastin; Hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, Alzheimer's Disease |
| 07/17/2008 | US20080171871 2,2-Dichloro-N-[2-[3-(2-chloro-6-fluorophenyl)-5-isoxazolyl]-(4-pyridyl)]Acetamide; Hepatitis C virus |
| 07/17/2008 | US20080171870 Reacting 4-Morpholin-4-ylmethyl-benzoic acid with 1-cyclopropyl-piperazine dihydrochloride producing (4-Cyclopropyl-piperazin-1-yl)-(4-morpholin-4-ylmethyl-phenyl)-methanone; sleep disorders, attention deficit hyperactivity disorders (ADHD), learning and memory disorders |
| 07/17/2008 | US20080171778 N3 alkylated benzimidazole derivatives as mek inhibitors |
| 07/17/2008 | US20080171743 Transcutaneous immunostimulation |
| 07/17/2008 | US20080171741 e.g. 5-(4-Chlorophenyl)-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)furan-2-carboxamide; p38 alpha and beta kinase inhibitor; antiinflammatory agent; asthma, inflammatory bowel disease, osteoporosis, psoriasis, graft vs. host rejection, atherosclerosis, multiple myeloma, pain, myocardial ischemia |
| 07/17/2008 | US20080171733 Antiinflammatory agents, antidepressants, analgesics, purinergic receptor antagonists; neurodegenerative diseases, spinal cord injuries; 1-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]-1H-tetraazol-5-amine |
| 07/17/2008 | US20080171724 Phosphonate Derivatives of Mycophenolic Acid |
| 07/17/2008 | US20080171692 Substituted amides |
| 07/17/2008 | CA2674843A1 Factor xa inhibitors |
| 07/17/2008 | CA2674318A1 Cyclized derivatives as eg-5 inhibitors |
| 07/17/2008 | CA2673654A1 5-pyridinone substituted indazoles |
| 07/17/2008 | CA2672307A1 Bipiperidinyl compounds, compositions containing such compounds and methods of treatment |
| 07/16/2008 | EP1944305A1 Quinoline derivatives as phosphodiesterase inhibitors |
| 07/16/2008 | EP1944304A1 Novel sustituted 1H-dihydropyrazoles, their preparation and use |