Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
09/2008
09/12/2008WO2008091580A3 Fungicidal amides
09/12/2008WO2008089933A3 Benzoquinazole derivatives
09/12/2008WO2008070016A3 Inhibitors of akt activity
09/12/2008WO2008012227A8 Pyrazoles as glucokinase activators
09/12/2008WO2004078116A9 P38 inhibitors and methods of use thereof
09/12/2008CA2680177A1 Metalloprotease inhibitors containing a heterocyclic moiety
09/12/2008CA2680173A1 Metalloprotease inhibitors containing a heterocyclic moiety
09/12/2008CA2679305A1 Pyrrole compounds
09/12/2008CA2679249A1 Compounds and compositions as modulators of gpr119 activity
09/12/2008CA2679101A1 Heterocyclic compounds, compositions comprising them and methods of their use
09/11/2008US20080221206 less anesthetic activity, but with more anti-inflammatory and spasmolytic activity; asthma, rhinitis, allergic urticaria, chronic lung inflammation associated with eosinophilia, following the example of atopic asthma and chronic intestinal inflammation, as colitis for instance
09/11/2008US20080221196 Pharmaceutically active isoindoline derivatives
09/11/2008US20080221178 Benzimidazole Derivatives,Compositions Containing Them, Preparation Thereof and Uses Thereof
09/11/2008US20080221122 cancer and non-cancer diseases associated with vascular proliferation; mitoxantrone resistant, taxol resistant cancers
09/11/2008US20080221116 for the treatment of benign prostatic hypertrophy and/or lower urinary tract symptoms; with finasteride
09/11/2008US20080221103 4-(3-Methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-ylamino)-6-(methylthio)-2-phenylpyrimidine-5-carbonitrile; having significant in vitro TNF- alpha inhibitory activity useful for the treatment of various inflammatory diseases such as arthritis, inflammatory bowel disease, psoriasis, asthma, COPD, cancer etc.
09/11/2008US20080221100 Soluble epoxide hydrolase inhibitors
09/11/2008US20080221095 increased potency and selectivity in relation to currently known MMP-13, MMP-8 and MMP-3 inhibitors; treating rheumatoid arthritis, osteoarthritis or inflammation; squaramide or benzoxazinone moiety
09/11/2008US20080221094 Metalloprotease inhibitors containing a squaramide moiety
09/11/2008US20080221093 Metalloprotease inhibitors containing a heterocyclic moiety
09/11/2008US20080221086 Novel Inhibitors of Glutaminyl Cyclase
09/11/2008US20080221082 of the alpha V beta 3 integrin receptor; , thromboembolic events, cardiovascular disorders, lung diseases, disorders of the CNS, the kidney, the gastrointestinal tract or inflammation
09/11/2008US20080216606 Grinding to uniform particle size; heating; pressurization;; extraction from ores, concentrates
09/10/2008EP1967519A1 3,4-dihydrobenzoxazine compound and inhibitor of vanilloid receptor type 1 (vr1) activity
09/10/2008EP1967517A1 Probe for diagnosis of conformational disease
09/10/2008EP1966195A2 5-aryl isoxazolines for controlling invertebrate pests
09/10/2008EP1966187A1 Piperazine compounds useful as antagonists of c-c chemokines (ccr2b and ccr5) for the treatment of inflammatory diseases
09/10/2008EP1966176A1 Heterocyclic gaba-b modulators
09/10/2008EP1966171A1 Improved process for the preparation of 4-(benzimidazolylmethylamino)-benzamides and the salts thereof
09/10/2008EP1966170A2 Estrogen modulators
09/10/2008EP1966167A1 Diaryltriazolmethylamine derivatives, preparation and therapeutic use thereof
09/10/2008EP1966151A1 Polycyclic indazole derivatives that are erk inhibitors
09/10/2008EP1966144A1 Nicotinic acid derivatives as modulators of metabotropic glutamate receptors
09/10/2008EP1966134A1 Novel fused pyrrole derivatives
09/10/2008EP1966132A2 Compounds which modulate the cb2 receptor
09/10/2008EP1965807A2 S1p receptor modulating compounds and use thereof
09/10/2008EP1965645A2 Isoxazolines for controlling invertebrate pests
09/10/2008EP1597240B1 Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for the production thereof
09/10/2008EP1438053B1 Pyrimidine derivatives, pharmaceutical agent containing said compounds, use and method for making same
09/10/2008EP1437349B9 Substituted isoxazoles and the use thereof as antibiotics
09/10/2008EP1323710B1 Nitrogenous five-membered ring compounds
09/10/2008CN101263139A Isoxazolo derivatives as GABA A alpha5 inverse agonists
09/10/2008CN101263138A Salicylate and gentisate salts of a piperazine compound
09/10/2008CN101263137A Compound having oxadiazole ring structure bonded with aromatic heterocyclic ring and organic electroluminescent device
09/10/2008CN101263133A New pyridine analogues
09/10/2008CN101263125A Quinazoline derivatives useful in cancer treatment
09/10/2008CN101263124A Quinazoline derivatives useful in cancer treatment
09/10/2008CN101263116A Novel heterobicyclic derivatives useful as inhibitors of liver carnitine palmitoyl transferase
09/10/2008CN101260106A Raf kinase inhibitor, preparing method and use thereof
09/10/2008CN101260075A Aralkylpiperidine derivative and application thereof in preparing analgesic and sedative medicament
09/09/2008US7423159 Agent for preventing or treating neuropathy
09/09/2008US7423156 Optionally fused oxazolyl- or thiazolyl-aminophenylbenzoyl(cyclo)alkanoic acid derivatives, e.g., trans-(1R,2R)-2-({3'-fluoro-4'-,[(6-fluoro-1,3-benzothiazol-2-yl)amino]-1,1'-biphenyl-4-yl}carbonyl)cyclopentanecarboxylic acid; diacylglycerol O-acyltransferase type 1 inhibitors
09/09/2008US7423150 Substituted benzazoles and methods of their use as inhibitors of Raf kinase
09/09/2008US7423148 Small molecule PI 3-kinase inhibitors and methods of their use
09/09/2008US7423147 Therapy of Histamine H3 receptor mediated diseases
09/09/2008US7423058 Inhibitors of hepatitis C virus NS3 protease
09/09/2008US7423052 Piperidine compounds for use as orexin receptor antagoinst
09/09/2008US7423049 e.g., 2-(5-fluoro-2-tolyl)-4-(4-aminocarbonylpiperazinylmethyl)-6-[a-aminocarbonyl-2,6-dichlorobenzyl]pyridine; mitogen-activated protein kinase inhibitor; antiinflammatory agent, autoimmune diseases
09/09/2008US7423048 eating disorders of disturbed fundus such as dyspepsia, early satiety, bloating, anorexia; fundic relaxation; 1-(1-((2,3-dihydro(1,4)dioxino(2,3-b)pyridin-3-yl)methyl) -4- piperidinyl)-2-imidazolidinone; improved pharmacokinetics, less vasoconstriction, side effect reduction, sustain release
09/09/2008US7423040 Stable crystalline form of bifeprunox mesylate, dosage forms thereof and methods for using same
09/09/2008US7423038 Compounds and compositions as protein kinase inhibitors
09/09/2008US7423037 Morpholine derivatives as norepinephrine reuptake inhibitors
09/09/2008US7423036 Long-acting betamimetics for the treatment of respiratory complaints
09/09/2008US7423030 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof
09/09/2008CA2252163C D-proline derivatives
09/09/2008CA2225756C Substituted cyanophenyl uracils
09/04/2008WO2008106047A2 Carbamate compounds
09/04/2008WO2008105607A1 Heteroaryl-imidazole derivatives as cannabinoid cb1 receptor antagonists
09/04/2008WO2008105515A1 Novel hydroxamic acid derivative
09/04/2008WO2008105442A1 Sulfonamide derivative
09/04/2008WO2008105408A1 Novel pyrrole derivative having ureide group and aminocarbonyl group as substituents
09/04/2008WO2008104875A1 Oxazolidinones as cholesterol absorption inhibitors
09/04/2008WO2008104869A1 Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases
09/04/2008WO2008104754A1 Novel pyrimidine derivatives 698
09/04/2008WO2008104512A2 Novel polymorphs of aprepitant and processes for preparation
09/04/2008WO2008104472A1 2, 4 -diaminopyrimidine derivatives and their use as p2x antagonists or as prodrugs thereof
09/04/2008WO2008104135A1 A method for the preparation of zolmitriptan
09/04/2008WO2008104134A2 A method for the preparation of zolmitriptan
09/04/2008WO2008104077A1 Small molecule inhibitors of protein arginine methyltransferases (prmts)
09/04/2008WO2008047229A3 Biaryl ether urea compounds
09/04/2008US20080214645 Administering 2-(1H-1-Indol-3-ylsulfanyl)benzyl]dimethyl amine; general anxiety disorder, social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, panic attacks, specific phobias, social phobia and agoraphobia
09/04/2008US20080214644 [2-(4-Fluoro-]. H-indol-3-ylsulfanyl)benzyl]dimethyl amine; depression, anxiety disorders including general anxiety disorder, social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, panic attacks
09/04/2008US20080214623 N-(2,2-Dimethylpropyl)-6-{3-fluoro-5-[(3-isoxazolylamino)carbonyl]-2-methylphenyl}-3-pyridinecarboxamide; inhibitors of p38 kinase
09/04/2008US20080214620 Novel inhibitors of glutaminyl cyclase
09/04/2008US20080214617 antitumor agents; anticancer agents; structurally related to the leptomycin family; Leptolstatin
09/04/2008US20080214608 4-Amino-3,3-dimethylpiperidine; reduced toxicity, and improved pharmacology and pharmacokinetics
09/04/2008US20080214565 Oxazolidinone Derivatives as Antimicrobials
09/04/2008US20080214546 N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
09/04/2008US20080214545 4-{3-tert-butyl-5-[({[4-(pyridin-4-yloxy)phenyl]amino}carbonyl)amino]-1H-pyrazol-1-yl}-N-(2-pyrrolidin-1-ylethyl)benzamide; antiproliferatives; angiogenesis inhibitors
09/04/2008US20080214544 N-(4-(6-(1-methyl-6-oxo-2-(phenylamino)-1,6-dihydropyrimidin-5-yl)pyridin-3-yloxy)pyridin-2-yl)pyrrolidine-1-carboxamide; anticarcinogenics, antiproliferatives, angiogenesis inhibitors; hepatocyte growth factor mediated diseases
09/04/2008US20080214543 Antiandrogen; prostate cancer; excellent oral pharmacokinetics
09/04/2008US20080214542 1-(5-methoxyisoindolin-2-yl)-6-[4-(3-trifluoromethylphenyl)piperazin-1-yl]hexan-1-one; amidation of an isoindole with a 4-phenylpyrimidinylalkanoic acid or amination of a N-haloalkylcarbonyl isoindole with a 4-phenylpyrimidine; antidepressant, neuroleptic agent; drug abuse, impotency, Parkinson's Disease
09/04/2008US20080214539 Benzisoxazole Piperidine Compounds and Methods of Use Thereof
09/04/2008US20080214537 Bridged phenanthridines
09/04/2008US20080214536 4-((4aR,10bR)-8,9-Dimethoxy-1,2,3,4,4a,10b-hexahydro-phenanthridin-6-yl)-N-(2-methoxyethyl)-N-methyl-benzamide; phosphodiesterase 4 inhibitors; respiratory system disorders
09/04/2008US20080214533 Anticoagulants, thrombolytic agents; amidating a p-(hydroxy-protected alkylamino)aniline with a (hetero)arylaminocarbonyl-(hetero)aryl carboxylic acid; deblocking, reacting with cyanogen bromide and cyclizing
09/04/2008US20080214526 Macrocyclic Compounds and Compositions Useful as Bace Inhibitors
09/04/2008US20080214524 e.g. N-[2-(3-fluorophenyl)ethyl]-N'-isoquinolin-5-ylurea; opioid receptor inhibitor; analgesic, antiinflammatory agent; inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity
09/04/2008US20080214448 Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide
09/04/2008US20080213822 Methods for diagnosing celiac sprue and reagents useful therein