Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
02/2006
02/08/2006EP1622869A1 Glyoxalase inhibitors
02/08/2006EP1622865A2 Novel bioisosteres of actinonin
02/08/2006EP1622611A1 Imidazolin-2-ylaminophenyl amides as ip antagonists
02/08/2006EP1622610A1 1-(2h-pyrazol-3-yl)-3- 4-[1-(benzoyl)-piperidin-4-ylmethyl]-phenyl -urea derivatives and related compounds as inhibitors of p38 kinase and/or tnf inhibitors for the treatment of inflammations
02/08/2006EP1318978B1 N-acylsulfonamide apoptosis promoters
02/08/2006CN1732159A 2-oxopyrimidine derivatives and their use as human leukocyte elastase inhibitors
02/08/2006CN1732154A Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
02/08/2006CN1732153A Novel piperidine derivatives as modulators of chemokine receptor CCR5
02/08/2006CN1732006A 3-(3,5-dioxo-4,5-dihydro-3h-(1,2,4)triazin-2-yl)-benzamide derivatives as P2X7-inhibitors for the treatment of inflammatory diseases
02/08/2006CN1732002A Derivatives of aryl-quinazoline/aryl-2amino-phenyl methanone which promote the release of parathyroid hormone
02/08/2006CN1731993A Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases
02/08/2006CN1240681C Nitrile derivatives as cathepsin K inhibitors
02/08/2006CN1240680C 1,4-pentadiene-3-ketone compound containing halogenoindyl, and method for preparing same and medicinal use thereof
02/08/2006CN1240679C 2- and 2,5-substituted phenylketoenols
02/07/2006US6995185 Δ1-pyrrolines used as pesticides
02/07/2006US6995181 hyterocyclylaminomethyl- or aminocarbonyl-substituted 9,10-ethanoanthracenes or their aza derivatives; treating obesity, diabetes, inflammatory and immune disorders
02/07/2006US6995179 N-type calcium channel blockers, antiischemic agents
02/07/2006US6995162 Substituted alkylamine derivatives and methods of use
02/07/2006US6995161 Central nervous system disorders
02/07/2006US6995160 Sodium channel blockers
02/07/2006US6995159 4-piperazin-1-yl-2-(pyridin-2-ylmethoxy)-pyrimidine, 2-(6-methyl-pyridin-2-ylmethoxy)-4-piperazin-1-yl-pyrimidine, and 2-(6-chloro-pyridin-2-ylmethoxy)-4-piperazin-1-yl-pyrimidine; for treatment of seizure and eating disorders; reduced side effects
02/07/2006US6995156 Platelet adenosine diphosphate receptor antagonists
02/07/2006US6995144 for example, 6-[2-[4-(2-fluorophenoxymethyl)piperidino]ethyl]-1H-pyrazin-2-one; therapeutic or prophylactic agent for diabetic neuralgia, HIV neuralgia, postherpetic neuralgia, nerve system disorders
02/07/2006CA2340202C Hydroxy pipecolate hydroxamic acid derivatives as mmp inhibitors
02/07/2006CA2273479C 6-phenylpyridyl-2-amine derivatives useful as nos inhibitors
02/07/2006CA2216288C Uracilic hydroquinone derivatives as type iv allergy inhibitors
02/02/2006WO2006012374A1 Substituted aryl-amine derivatives and methods of use
02/02/2006WO2006012310A2 Carbazole derivatives for treating polycystic kidney disease
02/02/2006WO2006012256A2 Fkbp binding composition and pharmaceutical use thereof
02/02/2006WO2006010965A1 Indole-2 -carboxamidine derivatives as nmda receptor antagonists
02/02/2006WO2006010750A1 Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
02/02/2006WO2006010577A1 Substituted 3-phenylpiperidine derivatives
02/02/2006WO2006010446A2 Medicinal use of receptor ligands
02/02/2006WO2005113511A9 Urea antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
02/02/2006WO2005110994A3 Substituted pyrazolyl urea derivatives useful in the treatment of cancer
02/02/2006WO2005105753A3 Naphthalimide derivatives, methods for their production and pharmaceutical compositions therefrom
02/02/2006WO2005032594A3 Alkylators linked to polyamides as dna binding agents
02/02/2006US20060025597 4-(Aminomethyl)-2-(2,6-dioxo(3-piperidyl))isoindoline-1,3-dione hydrochloride; cytokines level reduced; tumor necrosis factor inhibitors; nontoxic; anticarcinogenic agents; antitumor agents (solid/blood-borne); cardiovascular disorders; osteoporosis; antiinflammatory agents; autoimmune diseases
02/02/2006US20060025589 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes
02/02/2006US20060025468 Chiral pyrrolidine derivatives, and methods for preparing compounds thereof
02/02/2006US20060025461 Triazole derivative
02/02/2006US20060025459 Having Asp2 ( beta -secretase, BACE1 or Memapsin) inhibitory activity, for therapy of diseases characterised by elevated beta -amyloid levels or beta -amyloid deposits
02/02/2006US20060025456 Serotonin reuptake inhibitors; dimethyl-(2-pyridin-3-yl-cyclohex-1-enylmethyl)-amine and the corresponding dihydrochloride; analgesics, anxiety disorders; side effects reduction
02/02/2006US20060025451 Novel pyrazole compounds as transforming growth factor (TGF) inhibitors
02/02/2006US20060025433 Pyrimidine derivatives useful as inhibitors of PKC-theta
02/02/2006US20060025432 N-[2-[(3-Chloro-2-fluorobenzyl)thio]-6-[(2-hydroxy-1-methylethyl)amino]-4-pyrimidinyl]- 4-morpholinesulfonamide; asthma, antiallergens; rhinitis, chronic obstructive pulmonary disease, inflammatory bowel disease, irritable bowel syndrome, osteoarthritis, osteoporosis, rheumatoid arthritis, psoriasis
02/02/2006US20060025425 Benzimidazole and pyridylimidazole derivatives
02/02/2006US20060025423 2,3-Dichloro-N-(3-methoxy-5-methyl-2-pyrazinyl)-benzenesulphonamide; inflammatory diseases, such as asthma
02/02/2006US20060025416 Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
02/02/2006US20060025415 Compositions useful as inhibitors of voltage-gated sodium channels
02/02/2006US20060025413 3-(arylamino)methylene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
02/02/2006US20060025410 2,4-Pyrimidinediamine compounds and their uses
02/02/2006US20060025404 Such as 1-(4-{[1-(1-methylethyl)-4-piperidinyl]oxy}phenyl)-4-{[4-(methylsulfonyl)phenyl]carbonyl}piperazine; neurodegenerative disorders including Alzheimer's disease; allergic rhinitis
02/02/2006US20060025403 Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
02/02/2006US20060024704 Detection of markers in nascent proteins
02/02/2006US20060024317 Chemical linkers and conjugates thereof
02/02/2006US20060022193 As sensitizers, optical brighteners and electroluminescent materials; monomers for the synthesis of polymeric light emitting materials of electroluminescent elements
02/02/2006DE4314721B4 Nicht-wandernde 1-Hydrocarbyloxy-2,2,6,6-tetramethylpiperidin -1,3,5-triazinderivate als Polymerstabilisatoren Non-migratory 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin -1,3,5-triazine derivatives as polymer stabilizers
02/02/2006CA2574361A1 1, 3 substituted cycloamino derivatives and their use as histamine-3 receptor antagonists
02/02/2006CA2574155A1 Indole-2 -carboxamidine derivatives as nmda receptor antagonists
02/02/2006CA2572833A1 Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
02/02/2006CA2571587A1 Quaternary salt ccr2 antagonists
02/02/2006CA2571424A1 Bisarylurea derivatives useful for inhibiting chk1
02/02/2006CA2571324A1 Heterocycle-substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
02/02/2006CA2569507A1 Amido compounds and their use as pharmaceuticals
02/01/2006EP1621539A1 Heterocycle -substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
02/01/2006EP1621538A1 4-(2-furoyl)aminopiperidine compound useful as therapeutic agent for itching
02/01/2006EP1621196A1 Therapeutic and/or preventive agent for chronic skin disease
02/01/2006EP1620434A1 Fused bicyclic-substituted amines as histamine-3 receptor ligands
02/01/2006EP1620432A1 Nk-2 antagonist basic linear compounds and formulations containing them
02/01/2006EP1620430A1 Oxetane compounds containing maleimide functionality
02/01/2006EP1620429A1 Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
02/01/2006EP1620426A1 2-pyridyl substituted imidazoles as alk5 and/or alk4 inhibitors
02/01/2006EP1620420A2 Substituted carboxylic acids
02/01/2006EP1620411A2 Inhibitors of akt activity
02/01/2006EP1620410A1 Use of derivatives of 2, 4-dihydro- 1,2,4 triazole-3-thione as inhibitors of the enzyme myeloperoxidase (mpo)
02/01/2006EP1620408A2 Quinazoline compounds
02/01/2006EP1620395A1 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders
02/01/2006EP1620391A2 Cyclic derivatives as modulators of chemokine receptor activity
02/01/2006EP1620108A2 Pyrazole-amine compounds useful as kinase inhibitors
02/01/2006EP1620086A1 Compounds that modulate ppar activity and methods of preparation
02/01/2006EP1620082A2 Medical use of inhibitors of glutaminyl and glutamate cyclases
02/01/2006EP1390339B1 Process for the preparation of 7-substituted 3-alkyl-3h-isobenzofuran-1-one derivatives
02/01/2006EP1119563B1 Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
02/01/2006CN1729187A Substituted benzodioxepins
02/01/2006CN1729181A Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
02/01/2006CN1729178A N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines
02/01/2006CN1729175A Tetrahydroquinoline derivatives
02/01/2006CN1729173A N-(indolethyl-) cacloamine compounds
02/01/2006CN1729171A Modulation of anxiety through blockade of anandamide hydrolysis
02/01/2006CN1728999A Substituted 1-piperidin-3-yl-4-piperidin-4-yl-piperazine derivatives and their use as neurokinin antagonists
02/01/2006CN1239511C Novel pyrazine derivatives or salts thereof, containing the derives or the salts and intermediates for the preparation of both
02/01/2006CN1239496C Respiratory syncytial virus replication inhibitors
02/01/2006CN1239482C Positive modulators for nicotinic receptor agonists
02/01/2006CN1239472C HIV integrase inhibitors
01/2006
01/31/2006US6992194 suspending crystal strutured or amorphous lipitor in diluents comprising alcohols and/or water mixtures to cause conversion, then separating the diluents; monodispersity
01/31/2006US6992104 C7 carbonate taxane compositions
01/31/2006US6992087 Substituted aryl 1,4-pyrazine derivatives
01/31/2006US6991911 for detection of 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-methamphetamine (MDMA) anibody production; drug screening; haptens; immunogens
01/31/2006CA2314154C Azepine or larger medium ring derivatives and their use as pharmaceuticals