Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
12/2005
12/21/2005EP1606267A1 Pyrazine compounds as transforming growth factor (tgf) inhibitors
12/21/2005EP1606266A2 Chemical compounds
12/21/2005EP1606265A1 2, 4- di (phenylamino) pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
12/21/2005EP1606255A2 Cyclic derivatives as modulators of chemokine receptor activity
12/21/2005EP1606251A2 Inhibitors of the binding of chemokines i-tac or sdf-1 to the ccxckr2 receptor
12/21/2005EP1558582B1 Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
12/21/2005EP1432701B1 Heterocyclic compounds for use in the treatment of disorders of the urinary tract
12/21/2005EP1395558B1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
12/21/2005EP1395555B1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
12/21/2005EP1363897B1 Antagonists of mcp-1 function and methods of use thereof
12/21/2005EP1362039B1 Heterocyclic substituted carbonyl derivatives and their use as dopamine d3 receptor ligands
12/21/2005EP1307445B1 Benzofuran derivatives and their use as antibacterial agents
12/21/2005EP1178973B1 Pyrazinyl-piperazine- compounds, their use and preparation
12/21/2005CN1711249A Quinazolinone derivatives useful as anti-hyperalgesic agents
12/21/2005CN1711081A Proline derivatives having affinity for the calcium channel alpha-2-delta subunit
12/21/2005CN1232519C Method for producing 5-(1-piperazinyl)-benzofuran-2-carboxamide by transition metal-catalyzed amination
12/21/2005CN1232518C Bi-heterocyclic compounds with antitumour and chemosensitising activity
12/21/2005CN1232509C Novel diamino pyrazole derivatives and dyes containing said compounds
12/21/2005CN1232505C Substituted sulfamide (thio) carbonyl compounds
12/20/2005US6977268 Diacid isoindoleine amide derivative
12/20/2005US6977266 Pyridone derivatives having affinity for cannabinoid 2-type receptor
12/20/2005US6977264 For therapy and prophylaxis of obesity, diabetes
12/20/2005US6977263 Chemical compounds
12/20/2005US6977258 Antiinflammatory agents; cardiotonic agents; rheumatic diseases
12/20/2005CA2338206C High affinity ligands for nociceptin receptor orl-1
12/20/2005CA2324324C Treatment of pulmonary hypertension
12/20/2005CA2233560C Sulfonamide inhibitors of matrix metalloproteinases
12/20/2005CA2176962C N-substituted azabicycloheptane derivatives, their preparation and use
12/20/2005CA2114007C Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof
12/15/2005WO2005118577A1 Novel saperconazole crystalline forms and related processes, pharmaceutical compositions and methods
12/15/2005WO2005118576A1 Constrained himbacine analogs as thrombin receptor antagonists
12/15/2005WO2005118575A1 Non nucleoside reverse transcriptase inhibitors
12/15/2005WO2005118574A1 Mercaptoimidazoles as ccr2 receptor antagonists
12/15/2005WO2005118556A1 Propane-1,3-dione derivative or its salt
12/15/2005WO2005118547A1 Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
12/15/2005WO2005118544A2 Cycloalkyl substituted pyrimidinediamine compounds and their uses
12/15/2005WO2005118543A1 Kinase inhibitor and use thereof
12/15/2005WO2005118535A1 Substituted pyrrolidine-2-ones
12/15/2005WO2005118531A1 Aminomethyl-azacycle derivatives as inhibitors of monoamine uptake
12/15/2005WO2005117908A2 Triheterocyclic compounds compositions, and methods for treating cancer or viral diseases
12/15/2005WO2005117894A1 Leptomycin compounds
12/15/2005WO2005117882A2 Hydroxamic acid derivatives as metalloprotease inhibitors
12/15/2005WO2005117876A1 Dual small molecule inhibitors of cancer and angiogenesis
12/15/2005WO2005087751A3 Substituted hydroxyethylamine aspartyl protease inhibitors
12/15/2005US20050277685 peroxisome proliferator activated receptor agonist such as (2R)-2-(3-{[3-(4-chlorophenoxy)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl}phenoxy)butanoic acid, used for treatment and control of metabilic disorders
12/15/2005US20050277673 such as 4-{[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]methyl}tetrahydro-2H-pyran-4-carboxylic acid; serotonin receptor agonist; antidepressant, anxiolytic agent, analgesic, cognition activator; less toxicity, good absorption, and metabolic stability
12/15/2005US20050277672 such as 1-{[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]methyl}cyclopentanecarboxylic acid; serotonin receptor agonist; antidepressant, anxiolytic agent, analgesic, cognition activator; less toxicity, good absorption, and metabolic stability
12/15/2005US20050277671 Benzimidazolone carboxylic acid derivatives
12/15/2005US20050277669 Preparation of paroxetine involving novel intermediates
12/15/2005US20050277663 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides
12/15/2005US20050277660 Novel tetrahydroquinoline derivatives
12/15/2005US20050277658 Such as aurora-2 kinase or c-kit kinase; anticancer agents; based on benzo(4,5)furo(3,2-d)pyrimidine, 9-thia-1,5,7-triazafluorene, or pyrimido(5,4-b)indole rings; e.g. 6,7-dimethoxy-4-(4-(benzodioxol-5-ylmethylaminothiocarbonyl)-piperazin-1-yl)-5H-Pyrimido(5,4-b)indole
12/15/2005US20050277654 4,5-Disubstituted-2-aryl pyrimidines
12/15/2005US20050277653 Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
12/15/2005US20050277646 N-[4-({5-(4-fluorophenyl)-4-[4-(trifluoromethyl)phenyl]pyridin-2-yl}oxy)-1,3-benzothiazol-2-yl]acetamide; vanilloid (capsaicin) receptor antagonist/agonist; antiinflammatory, analgesic, antiarthritis, antirheumatic; diseases involving sensory nerve function
12/15/2005US20050277642 Pyrimidine kinase inhibitors
12/15/2005US20050277640 Pyrimidine derivatives for treatment of hyperproliferative disorders
12/15/2005US20050277638 Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
12/15/2005US20050277637 Arylindenopyridines and related therapeutic and prophylactic methods
12/15/2005US20050277631 Vanilloid receptor ligands and their use in treatments
12/15/2005DE102004025791A1 Chromanol-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer Chromanol derivatives, a process for their preparation and their use as anti-inflammatories
12/15/2005CA2568622A1 Dual small molecule inhibitors of cancer and angiogenesis
12/15/2005CA2568341A1 Leptomycin compounds
12/15/2005CA2566531A1 Cycloalkyl substituted pyrimidinediamine compounds and their uses
12/15/2005CA2565689A1 Substituted pyrrolidine-2-ones
12/15/2005CA2565280A1 Mercaptoimidazoles as ccr2 receptor antagonists
12/14/2005EP1604979A1 2-oxo-1-pyrrolidine derivative and its pharmaceutical uses
12/14/2005EP1603912A1 Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
12/14/2005EP1603911A1 Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
12/14/2005EP1603906A2 Process for synthesising useful intermediates for the preparation of alpha v beta 3 receptor antagonists
12/14/2005EP1603901A1 Tetrahydropyran compounds as tachykinin antagonists
12/14/2005EP1603897A1 Pyrazole compounds useful in the treatment of inflammation
12/14/2005EP1603893A1 Ep4 receptor antagonists
12/14/2005EP1603886A1 4-substituted-5-cyano-1h-pyrimidin-6-(thi)ones as gsk-3 inhibitors
12/14/2005EP1603885A1 Fused tri and tetra-cyclic pyrazole kinase inhibitors
12/14/2005EP1603883A2 Quinoline-derived amide modulators of vanilloid vr1 receptor
12/14/2005EP1603882A2 Urea and thiourea derivatives
12/14/2005EP1603880A1 Quinolinone/benzoxazinone derivatives and uses thereof
12/14/2005EP1603879A2 Substituted pyridine derivatives useful in the treatment of cancer and other disorders
12/14/2005EP1603874A2 G-lactam derivatives as prostaglandin agonists
12/14/2005EP1603572A1 Lactam-containing cyclic diamines and derivatives as factor xa inhibitors
12/14/2005EP1603570A2 Aminoheteroaryl compounds as protein kinase inhibitors
12/14/2005EP1326858B1 Piperidine compounds as anti-allergic
12/14/2005EP1224165B1 Novel compounds
12/14/2005EP1200411B1 Process for synthesis of heteroaryl-substituted urea compounds
12/14/2005CN1708560A Beta-isoindigo coloring agent
12/14/2005CN1708491A N-benzodioxolyl, N-benzodioxanyl and N-benzodioxepinyl arylcarbonxamide derivatives, and pharmaceutical compositions comprising them
12/14/2005CN1708481A N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobials
12/14/2005CN1708306A Quinazolinone compounds as calcilytics
12/14/2005CN1231762C Method for directly identifying candidate compound
12/14/2005CN1231476C Substd. pyridine herbicides
12/14/2005CN1231473C Substituted arylpyrazines
12/14/2005CN1231471C 4-amino-5-cyano-2-anilino-pyrimidine derivatives and their use as inhbitors of cell-cycle kinases
12/14/2005CN1231470C N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as polymerisation in hibitors
12/14/2005CN1231467C High affinity ligands for nociceptin receptor ORL-1
12/14/2005CN1231466C New piperidine derivatives
12/14/2005CN1231215C (Imidazol-5-yl) methyl-2-quinolinone derivatives as inhibitors of smooth muscle cell proliferation
12/13/2005US6974826 such as 3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-4-methoxybenzylidene-2,4-thiazolidinedione; Hodgkin's disease
12/13/2005US6974813 For therapy of perioperative myocardial ischemic injury in mammals, including humans
12/13/2005US6974812 such as 2-chloro-N-(1-hydroxy-cycloheptylmethyl)-5-[4-(2-hydroxy-3-methoxy-propyl)-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl]-benzamide; purinergic receptors (P2x7 E); for treatment of interleukin-1 associated disorders (rheumatoid arthritis)