Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
11/2005
11/24/2005WO2005109987A2 3-(((4-phenyl)-piperazine-1-yl)-alkyl)-3-alkyl-1, 3-dihydro-2h-indol-2-one derivatives and related compounds for the treatment of central nervous system disorders
11/24/2005WO2005085198A3 Amino cyclopropane carboxamide derivatives as bradykinin antagonists
11/24/2005WO2005046604A3 Heteroaryl-hydrazone compounds
11/24/2005US20050261502 2-Amino-4-(1,3-benzodioxol-5-yl)-6-benzyloxy-3,5-pyridinedicarbonitrile, acting as adenosine-receptor-selective ligands, for the prophylaxis and/or treatment of cardiovascular disorders
11/24/2005US20050261501 e.g. 1-({[9-(hydroxymethyl)-3-oxaspiro[5.5]undec-9-yl]amino}acetyl)-2-pyrrolidinecarbonitrile; dipeptidyl-peptidase IV inhibitor; antidiabetic, hypoglycemic agent; non-insulin dependent diabetes, obesity
11/24/2005US20050261496 3-(Morpholin-4-ylsulfonyl)-5-(1,3-thiazol-2-yl)-1H-indole-2-carboxamide; inhibiting, modulating and/or regulating signal transduction of both receptor and non-receptor tyrosine kinases; anticarcinogenic, -diabetic, -arhtritic, -inflammatory agents; psoriasis; angiogenesisinhibitors; liver cirrhosis
11/24/2005US20050261361 Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
11/24/2005US20050261360 Dissolving the crystalline form in acetone, allowing to convert to amorphous form and then precipitating it out
11/24/2005US20050261359 Novel processes for preparing amorphous atorvastatin hemi-calcium
11/24/2005US20050261353 Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
11/24/2005US20050261343 Anthranilamides and their use as pharmaceutical agents
11/24/2005US20050261339 Jun N-terminal kinase inhibitors; neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; multiple sclerosis; spinocerebellar ataxia
11/24/2005US20050261330 Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents
11/24/2005US20050261324 Pyrimidine hydantoin analogues which inhibit leukocyte adhesion mediated by VLA-4
11/24/2005US20050261320 Compounds and methods for the treatment of cancer
11/24/2005US20050261319 Novel 2-amino-4-quinazolinones and 2-amino-4-oxoquinazolones as LXR nuclear receptor binding compounds with partial agonistic properties
11/24/2005US20050261318 Protein kinase inhibitors
11/24/2005US20050261315 tyrosine kinase inhibitors such as N-(3-tert-butylisoxazol-5-yl)-2-(4-(benzyloxy)phenyl)acetamide, used for treating and preventing conditions and diseases, such as cancer, hematologic malignancies, cardiovascular disease, inflammation or multiple sclerosis
11/24/2005US20050261313 For angiogenesis mediated diseases; cancer; acylation, cyclization and Heck-type reduction
11/24/2005US20050261308 1-(2-Chloro-6-piperazin-1-yl-pyrimidin-4-ylmethyl)-3,4-dihydro-1H-quinolin-2-one; substituted benzoxazinone compounds; 5-HT6 modulators/antagonists; Parkinson's disease, Huntington's disease, manic depression, psychoses, Alzheimer's disease and memory disorders
11/24/2005US20050261301 e,g, 1,5-bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)pentane;potassium channel modulator; antiinflammatory agent, autoimmune diseases; immunosuppressant; multiple sclerosis, rejection of foreign organ transplants
11/24/2005US20050261299 e.g. 4-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1(3)H-imidazol-2-yl)methyl)benzamide; transforming growth factor- beta (TGF- beta ) type I receptor (ALK5) and/or the activin type I receptor (ALK4) antagonist; wound healing agent, antidiabetic, anticarcinogenic, antiinflmmatory agent
11/24/2005US20050261293 Compounds which inhibit leukocyte adhesion mediated by VLA-4
11/24/2005US20050261291 1-Cyclopropylmethyl-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine or a salt or hydrate; exhibit excellent cell adhesion inhibitory action or cell infiltration inhibitory action; for treating inflammatory diseases and autoimmune diseases such as inflammatory bowel diseases and rheumatoid arthritis
11/24/2005US20050261290 Novel compounds of proline and morpholine derivatives
11/24/2005US20050261285 Tetrahydropyran derivatives and their use as therapeutic agents
11/24/2005US20050261279 antipsychotic agents; phenylsulfonyl compounds; 7-Methoxy-8-(3-phenoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-3-benzazepine; schizophrenia
11/24/2005US20050261273 Substituted urea and carbamate, phenacyl-2-hydroxy-3-diaminoalkane, and benzamide-2-hydroxy-3-diaminoalkane aspartyl-protease inhibitors
11/24/2005US20050261244 Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
11/24/2005US20050261242 nitroso derivatives of drugs such as antiinflammatory agents, antibiotics, expectorants, mucolytic agents, antidiabetics, antitumor, viricides, enzyme inhibitors bronchodilators and antiulcer agents; oxidative and endothelial stress dysfunction; free radicals scavenger
11/24/2005CA2566707A1 Pyrimidine derivatives for the treatment of abnormal cell growth
11/24/2005CA2565953A1 Piperidine derivatives as nk1 and nk3 antagonists
11/24/2005CA2565514A1 3-(((4-phenyl)-piperazine-1-yl)-alkyl)-3-alkyl-1, 3-dihydro-2h-indol-2-one derivatives and related compounds for the treatment of central nervous system disorders
11/24/2005CA2565238A1 Amido compounds and their use as pharmaceuticals
11/24/2005CA2565211A1 Amino-tetrazoles analogues and methods of use
11/24/2005CA2564517A1 1-aryl-4-substituted isoquinolines
11/24/2005CA2564489A1 Tetrahydropyranyl cyclopentyl 1-substituted and 1,1-disubstituted tetrahydroisoquinoline modulators of chemokine receptor activity
11/24/2005CA2564325A1 Substituted pyrazolyl urea derivatives useful in the treatment of cancer
11/24/2005CA2563607A1 4,5-disubstituted-2-aryl pyrimidines
11/23/2005EP1598350A1 Pyrrolidines and thiazolidines derivatives, their preparation and their use in the treatment of hyperglycaemia and of type II Diabetis
11/23/2005EP1598345A1 Benzopyran compounds, process for preparing the same and their use
11/23/2005EP1598340A1 1-(4-piperidinyl)-1,3-dihydro-2h-benzoxazole-2-one derivatives and related compounds as nociceptin analogs and orl1 ligands for the treatment of pain
11/23/2005EP1598339A1 1-(4-amino-cyclohexyl)-1,3-dihydro-2h-benzimidazole-2-one derivatives and related compounds as nociceptin analogs and orl1 ligands for the treatment of pain
11/23/2005EP1598338A1 1-(4-piperidinyl)-1,3-dihydro-2h-indole-2-one derivatives and related compounds as nociceptin analogs and orl1 ligands for the treatment of pain
11/23/2005EP1597257A1 Oxazole-derivatives as ppar agonists
11/23/2005EP1597254A1 Indole-derivative modulators of steroid hormone nuclear receptors
11/23/2005EP1597253A2 Compounds and methods of treating cell proliferative diseases, retinopathies and arthritis
11/23/2005EP1597252A1 Pyridine derivatives as fungicidal compounds
11/23/2005EP1597251A2 Pyrimidine compounds
11/23/2005EP1597249A1 Anthelmintic agents and insecticidal compositions
11/23/2005EP1597246A2 Inhibitors of hepatitis c virus rna-dependent rna polymerase, and compositions and treatments using the same
11/23/2005EP1597240A1 Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for the production thereof
11/23/2005EP1597233A1 Benzyl urea and thiourea derivatives useful as androgen antagonists
11/23/2005EP1597228A2 Substituted n-arylheterocycles, method for production and use thereof as medicaments
11/23/2005EP1597223A2 Hydroxyl compounds and compositions for cholesterol management and related uses
11/23/2005EP1597084A2 Imaging system
11/23/2005EP1596656A2 Pyrazoles and methods of making and using the same
11/23/2005EP1320522B1 Compositions and methods of the use thereof achiral analogues of cc-1065 and the duocarmycins
11/23/2005EP1280777B1 Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
11/23/2005EP1066261B1 Pyridine derivative and pharmaceutical containing the same
11/23/2005EP0938474B1 Cyclopropylindole compounds and their use as prodrugs
11/23/2005EP0811007B1 Pyrazol-4-yl-benzoyl derivatives and their use as herbicides
11/23/2005CN1701068A Novel compounds and their use
11/23/2005CN1699350A Processes and intermediates for preparing anti-cancer compounds
11/23/2005CN1699347A Substituted pyrazolyl benzenesulfonamides for the treatment of inflamation
11/23/2005CN1228338C Imidazole derivatives or salts thereof and drugs contg. derivatives or salts
11/22/2005US6967249 Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith
11/22/2005US6967205 Compounds with antibacterial and antiparasitic properties
11/22/2005US6967201 Benzofurylpiperazines and benzofurylhomopiperazines: serotonin agonists
11/22/2005US6967079 Pyrimidine derivatives for labeled binding partners
11/22/2005CA2180445C Chemical switching of taxo-diterpenoids between low solubility active forms and high solubility inactive forms
11/22/2005CA2068066C Herpesvirus particles and vaccine
11/17/2005WO2005108393A1 Pyrrole or imidazole amides for treating obesity
11/17/2005WO2005108389A1 Indole derivatives having piperidine rings
11/17/2005WO2005108384A1 3- or 4-monosubstituted phenol and thiophenol derivatives useful as h3 ligands
11/17/2005WO2005108370A1 Benzene compounds
11/17/2005WO2005108369A1 Phenyl compounds and their use in the treatment of conditions mediated by the action of pge2 at the ep1 receptor
11/17/2005WO2005108364A1 Piperazine derivatives of alkyl oxindoles
11/17/2005WO2005108360A1 Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
11/17/2005WO2005108359A1 Novel compounds of proline and morpholine derivatives
11/17/2005WO2005107742A1 Novel antiviral helioxanthin analogs
11/17/2005WO2005091752A3 Acrylonitrile derivatives for inflammation and immune-related uses
11/17/2005WO2005090334A3 Processes and intermediates for the preparation of aspartic acetal caspase inhibitors
11/17/2005WO2005085177A3 Biaryl amino acids and their use in dna binding oligomers
11/17/2005WO2005058834A3 Quinolines useful in treating cardiovascular disease
11/17/2005WO2004074281A8 Benzofuran oxyethylamines serving as antidepressant drugs and anxiolytic drugs
11/17/2005US20050256315 1h-benzo{f}indazol-5-yl derivatives as selective glucocorticoid receptor modulators
11/17/2005US20050256311 Pyrimidine compounds
11/17/2005US20050256309 Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands
11/17/2005US20050256185 Spiro and dispiro 1,2,4-trioxolane antimalarials
11/17/2005US20050256180 drugs such as 1 -[4-(aminosulfonyl)phenyl]-8-{[(trifluoromethyl)sulfonyl]amino}-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide, used as antiinflammatory agents, antiarthritic agents, antipyretics or analgesics
11/17/2005US20050256170 EP receptor (for which the endogenous ligand is prostaglandin E2, PGE2); e.g. (4-[(5-Phenyl-furan-2-carbonyl)-amino]-phenyl)-acetic acid or 5-Phenyl-furan-2-carboxylic acid [3-(1H-tetrazol-5-yl)-phenyl]-amide; dysmenorrhoea, preterm labour, glaucoma, immune disorders, inflammatory disorders
11/17/2005US20050256167 Preparation and use of imidazole derivatives for treatment of obesity
11/17/2005US20050256166 Nitrogen-containing compounds
11/17/2005US20050256164 NK1 and NK3 antagonists
11/17/2005US20050256160 Beta-alanine derivatives and the use thereof
11/17/2005US20050256159 1,4-disubstituted piperidine derivatives and their use as 11,betahsd1 inhibitors
11/17/2005US20050256158 PGD2 receptor antagonists for the treatment of inflammatory diseases
11/17/2005US20050256145 Pyrimidine derivatives for the treatment of abnormal cell growth
11/17/2005US20050256137 Pyridone compounds as inhibitors of bacterial type III protien secreation systems