Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 305 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
Patents for C07D 305 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms (5,442)
11/1999
11/11/1999WO1999057105A1 Methods and useful intermediates for paclitaxel synthesis from c-7, c-10 di-cbz baccatin iii
11/11/1999CA2331094A1 Methods and useful intermediates for paclitaxel synthesis from c-7, c-10di-cbz 10-deacetylbaccatin iii
11/10/1999CN1046261C Synthesis of taxol and its derivatives
11/10/1999CN1046216C Catalyst for preparing 1,4-butanediol and/or gamma-butyrolactone
11/09/1999US5981782 Exhibits high catalytic activity and allows asymmetric reaction in a high asymmetric yield to obtain a reaction product having a high optical purity
11/09/1999US5981777 Recovery of taxanes from plant material
11/09/1999US5981771 Intermediate for raw material of polymer, synthetic material for medicines, liquid crystals; asymmetric hydrogenation of 4-methylene-2-oxetanone in the presence of ruthenium-iodo-optically active phosphine catalyst complex
11/09/1999US5981768 1,2 chemiluminescent dioxetanes of improved performance
11/09/1999US5981564 Water-soluble derivatives of paclitaxel, method for producing same and uses thereof
11/04/1999WO1999048894B1 Novel cephalotaxane derivatives and process for their preparation
11/02/1999US5977386 Antitumor
11/02/1999US5977375 Esters of baccatin III and 10-deacetylbaccatin III
11/02/1999US5977164 Antitumor
11/02/1999CA2077621C Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
10/1999
10/28/1999WO1999054322A1 The semi-synthesis of baccatin iii
10/27/1999EP0935596A4 Method for paclitaxel synthesis
10/27/1999EP0871620A4 Biocatalytic methods for synthesizing and identifying biologically active compounds
10/26/1999US5973170 Dissolving baccatin; cooling; adding alkali base; selectivityacylation
10/26/1999US5973163 Oxazolidine carboxylic acid intermediates for esterification of taxanes
10/26/1999US5973160 Contacting an oxazoline derivative with a taxane having hydroxyl group directly bonded at c-13 in presence of a coupling agent
10/26/1999US5972992 Comprising taxol and a pharmaceutically-acceptable carrier wherein said pharmaceutical taxol composition has a ph less than or equal to 7; improved stability
10/21/1999WO1999052887A1 7-hexanoyltaxol and methods for preparing the same
10/21/1999CA2327791A1 7-hexanoyltaxol and methods for preparing the same
10/20/1999EP0949918A1 7-deoxy-6-substituted paclitaxels
10/20/1999CN1232011A Process for preparing chlorohydrin in tubular reactor
10/19/1999US5969165 Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column
10/19/1999US5968931 Taxoids, preparation thereof and pharmaceutical compositions containing same
10/13/1999EP0817780B1 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
10/12/1999US5965779 Fluorooxetane compound and process for its preparation
10/12/1999US5965752 Extracting organic matter from taxus genus into organic solvent; washing extract and filtering over charcoal to remove solvent; dissolving residue in solvent and adding second solvent; recrystallizing and separating crystals
10/12/1999US5965739 Oxazolidine protected taxol analogs of given formula, and methods of synthesis from an oxazolidine free acid and a baccatin compound in the presence of a dehydrating agent; useful intermediates to make various taxol analogues
10/12/1999US5965566 High molecular weight polymer-based prodrugs
10/06/1999CN1230953A Method for paclitaxel synthesis
10/06/1999CN1230542A Sidechain-bearing taxanes
10/05/1999US5962705 Process for preparing derivatives of the taxoid family
10/05/1999CA2158147C Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
09/1999
09/30/1999WO1999048894A1 Novel cephalotaxane derivatives and process for their preparation
09/30/1999WO1999033462A9 2-aroyl-4-acyl paclitaxel (taxol) analogs
09/30/1999CA2324895A1 Novel cephalotaxane derivatives and process for their preparation
09/29/1999CN1045289C Process for mfg. alkyl ketene dimer
09/28/1999US5959125 Esterifying a baccatin iii derivative with an acid derivative; antitumor and anticarcinogenic agent
09/28/1999US5958741 Process for producing taxol, using a taxol producing microbe followed by separation of taxol from the growth medium and/or microbe; culturing fungal tissue fragments from a tree of the genus taxus
09/22/1999CN1045174C Method for producing gamma-butyrolactone
09/21/1999US5955621 Recovery of Taxanes from conifers
09/15/1999EP0942051A2 Coating composition comprising a bicyclo-or spiro-orthoester-functional compound
09/15/1999EP0941219A1 Intermediate for use in docetaxel synthesis and production method therefor
09/15/1999EP0941089A2 Compositions and methods for treating or preventing inflammatory diseases
09/14/1999CA2098478C Preparation of substituted isoserine esters using metal alkoxides and .beta.-lactams
09/10/1999WO1999045001A1 Synthesis of paclitaxel baccatin iii by protecting the 7-hydroxyl using a strong base and an electrophile
09/10/1999CA2319043A1 Synthesis of paclitaxel baccatin iii by protecting the 7-hydroxyl using a strong base and an electrophile
09/07/1999US5948919 Paclitaxel synthesis from precursor compounds and methods of producing the same
09/01/1999EP0918764A4 Method for acylating 10-deacetylbaccatin iii selectively at the c-10 position
09/01/1999EP0605638B1 Metal alkoxides
09/01/1999CN1044866C Catalyst for preparing gamma-butyrolactone by maleic anhydride gas-phase hydrogenation
08/1999
08/24/1999CA2116335C Chiral catalysts, catalytic oxidation and disproportionation reactions, and methods of producing epoxychromans and taxol
08/18/1999EP0935596A1 Method for paclitaxel synthesis
08/17/1999US5939567 Reacting stoiochiometric amount of fatty acid chloride or anhydride with taxane to attach the hydrocarbon chain to the hydroxy group at position 2' of taxane
08/17/1999US5939566 Syntheses of taxol, taxol analogs and their intermediates with variables A-ring side chain structures and compositions thereof
08/12/1999WO1999040216A1 Method for producing baccatin
08/11/1999CN1225633A Taxane derivatives and drugs contg. same
08/11/1999CN1044571C Catalyst for continuous hydrogenation to remove aldehyde for epoxy compound
08/04/1999EP0933360A1 Synthesis of new beta-lactams
08/04/1999EP0755387B1 Oxidative purification of biomass extracts containing taxol and cephalomannine using ozone and girard reagents
08/04/1999CN1225089A Method for acylating 10-deacetylbaccatin III selectively at the C-10 position
07/1999
07/29/1999WO1999037796A1 Process of extracting taxol from taxus cuspidata
07/29/1999WO1999037632A1 Alternate method for acylating 10-deacetylbaccatin iii selectively at the c-10 position
07/29/1999WO1999037631A1 Novel taxaneterpine compounds
07/29/1999WO1999037609A1 Novel naphthyl-substituted and anilide-substituted sulfonamides
07/29/1999WO1999037608A1 Novel naphthyl substituted and heterocyclic substituted sulfonamides
07/29/1999DE19802436A1 New N-aryl sulfonamides as antiviral agents, particularly against cytomegalovirus, e.g. in patients with acquired immune deficiency syndrome
07/29/1999CA2318182A1 Novel naphthyl-substituted and anilide-substituted sulfonamides
07/29/1999CA2312350A1 Alternate method for acylating 10-deacetylbaccatin iii selectively at the c-10 position
07/27/1999CA2007048C Process for the reduction of the polymer portion in the dimerization of ketene
07/22/1999WO1999036413A1 Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
07/22/1999CA2317728A1 Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
07/21/1999EP0930309A1 Taxane derivatives and drugs containing the same
07/20/1999CA2163837C Crystalline paclitaxel hydrates
07/14/1999CN1222518A Taxad alcohol cleaning and purifying method
07/13/1999US5922754 Pharmaceutical compositions containing paclitaxel
07/08/1999WO1999033462A1 2-aroyl-4-acyl paclitaxel (taxol) analogs
07/08/1999CA2328771A1 2-aroyl-4-acyl paclitaxel (taxol) analogs
07/07/1999EP0927175A1 1-deoxy baccatin iii, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof
07/06/1999US5919815 Taxane compounds and compositions
07/01/1999WO1999032473A1 Taxane derivatives
07/01/1999WO1999032109A1 7-deoxy-6-nitrogen substituted paclitaxels
07/01/1999CA2314071A1 Taxane derivatives
06/1999
06/30/1999EP0925786A1 Remedies for ischemic diseases
06/30/1999CN1221412A 1-deoxy baccatine III, 1-deoxy taxol and 1-deoxy taxol analogs and method for preparation thereof
06/29/1999US5917062 Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
06/29/1999US5917056 10-deacetyl-14β-hydroxybaccactine III derivatives, a process for the preparation thereof and formulations containing them
06/29/1999US5916783 Taxane composition obtained by culturing a biologically pure culture of a taxane-producing microbe, said microbe having been isolated from a tree of the genus taxus
06/24/1999WO1999031079A2 Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents
06/23/1999EP0924206A1 Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine
06/23/1999EP0923566A1 High molecular weight polymer-based prodrugs
06/23/1999EP0923565A1 Process for preparing paclitaxel
06/23/1999EP0639186B1 Taxol derivatives
06/22/1999US5914411 Alternate method for acylating 10-deacetylbaccatin III selectively at the C-10 position
06/22/1999CA2256865A1 Synthesis of new .beta.-lactams
06/16/1999CA2256033A1 Process for producing (r)-3-hydroxy-4-butyrolactone useful for preparing (r)-carnitine
06/15/1999US5912264 Taxane derivatives as antitumor agents
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