Patents
Patents for C07D 305 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms (5,442)
09/1995
09/14/1995WO1995024402A1 9-deoxotaxane compounds
09/14/1995CA2182103A1 9-deoxotaxane compounds
09/12/1995US5449790 Preparation of 10-deacetylbaccatin III and 7-protected-10-deacetylbaccatin III derivatives from 10-deacetyl taxol A, 10-deacetyl taxol B, and 10-deacetyl taxol C
09/08/1995WO1995023795A2 Process for preparing polyfluorooxetanes
09/06/1995EP0669918A1 Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
09/06/1995EP0669917A1 Extraction of taxanes by ion exchange media
09/06/1995EP0669916A1 Novel method for preparing taxane derivatives, novel derivatives thus obtained and compositions containing them.
09/05/1995USH1487 Antitumor agents; treatment of ovarian, breast and other cancers
08/1995
08/30/1995EP0668862A1 Oxidation of glycoside substituted taxanes to taxol or taxol precursors and new taxane compounds formed as intermediates
08/30/1995EP0668856A1 Inhibitors of farnesyl-protein transferase
08/30/1995EP0668762A1 Butenyl-substituted taxanes and composition
08/29/1995US5445809 Production of taxol from the yew tree
08/23/1995EP0667922A1 Process for the preparation of taxane derivatives, novel taxanes so obtained and antitumour and antileukaemia compositions containing same
08/23/1995EP0667772A1 Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
08/23/1995EP0667771A1 Antitumour compositions containing taxane derivatives
08/23/1995CN1107150A Method of using ion exchange media to increase taxane yields
08/16/1995EP0666857A1 Method for preparing taxane derivatives
08/16/1995CN1106701A Pharmaceutical composition
08/12/1995EP0674510A4 Injectable composition.
08/08/1995US5440057 Reacting a chemical intermediates with phosgene, then acylating with a compound selected from the group consisting of phenyllithium, lithium compound and organomagnesium bromide
08/08/1995US5440056 Antitumor agents
08/08/1995US5440055 Method and apparatus for extracting taxol from source materials
08/03/1995WO1995020582A1 Δ12,13-iso-taxol analogs, antineoplastic use and pharmaceutical compositions containing them
08/03/1995CA2179176A1 .delta.12,13-iso-taxol analogs, antineoplastic use and pharmaceutical compositions containing them
08/02/1995EP0664800A1 Novel taxane derivatives, their preparation and pharmaceutical compositions containing them
07/1995
07/26/1995EP0663910A1 Method of obtaining 10-deacetylbaccatine iii.
07/26/1995EP0663909A1 Method of obtaining 10-deacetylbaccatine iii.
07/26/1995EP0663907A1 Method of preparing taxane derivatives.
07/26/1995EP0663906A1 Method of preparing taxane derivatives.
07/26/1995EP0663905A1 Novel method of esterification of baccatine iii an 10-deacetylbaccatine iii.
07/26/1995EP0663901A1 METHOD FOR THE STEREOSELECTIVE PREPARATION OF A DERIVATIVE OF -g(b)-PHENYLISOSERINE AND ITS USE IN THE PREPARATION OF TAXANE DERIVATIVES.
07/26/1995EP0663824A1 Potassium channel activating compounds and methods of use thereof
07/19/1995EP0656000A4 Process of converting taxanes into baccatin iii and 10-deacetylbaccatin iii.
07/13/1995WO1995018798A1 Chemical switching of taxo-diterpenoids between low solubility active forms and high solubility inactive forms
07/13/1995WO1995018613A1 Self-assembled taxo-diperpenoid nanostructures
07/12/1995EP0661969A1 Use of taxol for treating lymphomas and breast cancer
07/10/1995EP0669918A4 Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them.
07/05/1995EP0660706A1 Method of reducing blood levels of total cholesterol and low-density lipoprotein cholesterol
07/04/1995US5430160 Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
06/1995
06/29/1995WO1995017395A1 Method for extracting and isolating 10-deacetylbaccatine iii
06/28/1995EP0659181A1 Sulfonamide inhibitors of hiv-aspartyl protease
06/07/1995EP0656000A1 Process of converting taxanes into baccatin iii and 10-deacetylbaccatin iii
06/06/1995US5422364 Water soluble taxol derivatives
05/1995
05/30/1995US5420311 Explosices, propellants
05/24/1995CN1102829A Synthese of taxol, taxol analogs and their intermediates with variable A-ring side chain structures and compositions thereof
05/18/1995WO1995013271A1 Novel taxoids, their preparation and pharmaceutical compositions containing them
05/18/1995WO1995013270A1 Novel taxicine derivatives, their preparation and pharmaceutical compositions containing them
05/18/1995CA2175384A1 Novel taxoids, their preparation and pharmaceutical compositions containing them
05/17/1995EP0497816B1 Treatment of hiv infections and compounds useful therein
05/16/1995US5416225 Total synthesis of taxol
05/11/1995WO1995012567A1 Total synthesis of taxol and analogues thereof
05/03/1995EP0627010A4 PROCESS FOR THE ISOLATION AND PURIFICATION OF TAXOL AND TAXANES FROM -i(TAXUS) spp.
05/03/1995EP0626953A4 Novel sidechain-bearing taxanes and intermediates thereof.
05/02/1995US5412116 Oxidation of glycoside substituted taxanes to taxol or taxol precursors and new taxane compounds formed as intermediates
05/02/1995US5412113 Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration
05/02/1995US5412112 Derivatives and preparation of 2,2-dimethyl-5-substituted phenoxy-pentanoic acids
05/02/1995US5412110 Enzymatic process to separate racemic mixtures of delta valerolactones
05/02/1995US5412107 Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas
05/02/1995US5411984 Water soluble analogs and prodrugs of taxol
04/1995
04/27/1995WO1995011247A1 Novel taxoids, preparation thereof and pharmaceutical compositions containing them
04/27/1995WO1995011241A1 Novel taxoids, their preparation and compositions containing them
04/27/1995WO1995011020A1 2'- and/or 7- substituted taxoids
04/27/1995CA2174350A1 2'- and/or 7- substituted taxoids
04/26/1995CN1101944A Enzymatic hydrolysis methods for the preparation of C-10 and C-13 hydroxyl-bearing taxanes, enzymatic esterification method for the preparation of C-10 acyloxy-bearing taxanes, and use thereof in.....
04/18/1995US5407674 Plant extracts
04/12/1995CN1101346A C2 taxane derivatives and pharmaceutical compositions containing them
04/11/1995US5405972 Highly diastereoselective; efficient; cyclization, cleavage, lactonization, blocking
04/06/1995WO1995009163A1 Method of preparing taxoids
04/04/1995US5403940 Vitamin D compound, method of preparing this compound and intermediate thereof
03/1995
03/23/1995WO1995007900A1 New cytotoxic agents
03/22/1995EP0643712A1 Spiro-oxetanes, process for preparing the same and medicaments
03/22/1995EP0643626A1 Chiral catalysts, catalytic oxidation and disproportionation reactions, and methods of producing epoxychromans and taxol
03/21/1995US5399774 Process for the production of ketene dimers
03/21/1995US5399726 Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
03/21/1995US5399720 Production of oxetanones
03/15/1995EP0642586A1 CULTURED $i(TAXUS) TISSUES AS A SOURCE OF TAXOL, RELATED TAXANES AND OTHER NOVEL ANTI-TUMOR/ANTI-VIRAL COMPOUNDS
03/15/1995EP0642503A1 10-desacetoxytaxol derivatives
03/08/1995EP0641334A1 Novel taxane derivatives, their preparation and compositions containing same
02/1995
02/28/1995US5393896 Treating ground yew parts with water, separating aqueous solution, extracting with organic solvent, desolventizing, crystallizing, isolating
02/28/1995US5393895 Extracting ground parts of yew plant with hydroalcoholic solution
02/22/1995EP0639577A1 Phosphonooxymethyl or methylthiomethyl ethers of taxane derivatives as antitumor agents
02/22/1995EP0639186A1 Taxol derivatives
02/22/1995EP0425555B1 Preparation of epoxy nitrates
02/15/1995EP0638317A1 Pharmaceutical composition
02/15/1995CN1098711A Process for the manufacture of alkyl ketene dimer
02/09/1995WO1995003795A1 Method of treating atherosclerosis or restenosis using microtubule stabilizing agent
02/02/1995WO1995003265A1 Synthesis of taxol and its derivatives
02/02/1995WO1995003036A1 Anti-angiogenic compositions and methods of use
02/02/1995CA2472404A1 Combination of stent and anti-angiogenic factor
02/02/1995CA2468375A1 Anti-angiogenic compositions, uses and methods
02/01/1995CN1027538C Method for preparation of oxetane derivatives
01/1995
01/26/1995WO1995002576A1 Process for the preparation of n-carbonylarylimines useful for the synthesis of therapeutically active taxoids
01/26/1995WO1995002400A1 Taxol derivatives
01/26/1995CA2167073A1 Process for the preparation of n-carbonylarylimines useful for the synthesis of therapeutically active taxoids
01/26/1995CA2165079A1 Taxol derivatives
01/25/1995CN1097746A C10 taxane derivatives and pharmaceutical compositions containing them
01/24/1995US5384399 Oxazinone compounds for the preparation of taxol
01/19/1995WO1995001969A1 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
01/18/1995CN1097416A Novel beta-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
01/10/1995US5380916 Method for the isolation and purification of taxane derivatives
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