Patents for C07D 239 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings (42,619) |
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08/14/2008 | WO2007106561A3 Prevention and treatment of cancer and other diseases |
08/14/2008 | US20080194820 Condensing 1(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl) ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic or aromatic hydrocarbon solvent, to give (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H-1,2,4-triazole-1-yl)butan-2-ol; purity |
08/14/2008 | US20080194604 Dissolving with anionic surfactant while controlling temperature; dehydration; stirring; filtration; hydroxy-3-methylglutaryl/3-/coenzyme a inhibitor; suppression of cholesterol biosynthesis |
08/14/2008 | US20080194603 Prevent transplant rejection; autoimmune diseases |
08/14/2008 | US20080194602 Mixing of active material with carrier; viricides |
08/14/2008 | US20080194600 Antiallergens; vision defects; skin disorders; antiinflammatory agents; infection therapy; sleep disorders; antiinflammatory agents; chronic obstructive pulmonary disorders; antiarthritic agents; antiulcer agents; inflammatory bowel disorders |
08/14/2008 | US20080194598 Pyrimidine Carboxylic Acid Derivatives and Use Thereof |
08/14/2008 | US20080194597 Platelet adp receptor inhibitors |
08/14/2008 | US20080194595 Quinazolinone Derivatives Useful as Vanilloid Antagonists |
08/14/2008 | US20080194588 Modulation of pathogcnicity |
08/14/2008 | US20080194586 Controlling non-insulin dependent diabetes; hypoglycemic agents; antilipemic agents; hypercholesterolemia; obesity |
08/14/2008 | US20080194583 Tubulin Inhibitors |
08/14/2008 | US20080194578 Quinazoline based egfr inhibitors containing a zinc binding moiety |
08/14/2008 | US20080194577 Antiallergens; asthma; autoimmune disease; pruritius; antiarthritic agents |
08/14/2008 | US20080194565 5-Phenyl-Pentanoic Acid Derivatives as Matrix Metalloproteinase Inhibitors for the Treatment of Asthma and Other Diseases |
08/14/2008 | US20080194558 Quinazoline analogs as receptor Tyrosine Kinase inhibitors |
08/14/2008 | US20080193423 Small organic molecule regulators of cell proliferation |
08/14/2008 | DE102008007755A1 New halogenated 4-formylbenzonitrile compounds useful e.g. intermediate for the synthesis of fine chemicals or pharmaceutical products, and as components of liquid crystalline compounds, which are useful in electro-display devices |
08/14/2008 | CA2677809A1 An improved process for preparation of rosuvastatin calcium |
08/14/2008 | CA2677336A1 Bicyclic heterocycles, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof |
08/13/2008 | EP1956010A1 Bicyclical heterocycles, medicines containing these compounds, their application and method for their production |
08/13/2008 | EP1956009A1 Aromatic compound |
08/13/2008 | EP1954283A2 Compounds for modulating trpv3 function |
08/13/2008 | EP1954277A2 Aminopyrimidines useful as kinase inhibitors |
08/13/2008 | EP1758870B1 4-phenyl-pyrimidine-2-carbonitrile derivatives |
08/13/2008 | CN101243070A Trombin inhibiting 2,4-dioxo-3,4-dihydropyrimidine derivatives |
08/13/2008 | CN101243056A Crystal of phenylalanine derivative, process for producing the same and use thereof |
08/13/2008 | CN101243055A Dihydropyrimidone multimers and their use as human neutrophil elastase inhibitors |
08/13/2008 | CN101242848A Pyrimidine compounds |
08/13/2008 | CN101242843A Aminopyrimidines as kinase modulators |
08/13/2008 | CN101239973A Substituted aminoquinazolinone (thione) derivative or salts thereof, intermediate compound therefor, pest-controlling agent and using method thereof |
08/13/2008 | CN100411219C Molecular-base electric double-stable negative-resistance component and its application |
08/12/2008 | US7411065 Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids |
08/12/2008 | US7410975 Small molecule toll-like receptor (TLR) antagonists |
08/12/2008 | US7410974 Halogenated Quinazolinyl nitrofurans as antibacterial agents |
08/12/2008 | US7410956 Caspase inhibitor prodrugs |
08/07/2008 | WO2008094909A2 Quinazolinone and fused pyrimidinone compounds and their use in treating sodium channel-mediated diseases or conditions |
08/07/2008 | WO2008093272A2 Controlled release of active aldehydes and ketones from equilibrated dynamic mixtures |
08/07/2008 | WO2008093205A2 A method for the purification of rosuvastatin intermediate |
08/07/2008 | WO2008092410A1 Preparation method of thioureas or salts thereof |
08/07/2008 | WO2008092231A1 Compounds for the prevention and treatment of cardiovascular diseases |
08/07/2008 | WO2008092199A1 Thiopyrimidine-based compounds and uses thereof |
08/07/2008 | WO2008030266A3 Insecticidal n-substituted (heteroaryl)alkyl sulfilmines |
08/07/2008 | WO2007098118A3 Antineoplastic and curcumin derivatives and methods of preparation and use |
08/07/2008 | US20080188657 Chemical process |
08/07/2008 | US20080188656 Process for the Synthesis of 5- (Methyl-1H-Imidazol-1-Yl) -3- (Trifluoromethyl) -Benzeneamine |
08/07/2008 | US20080188529 N1-(cyanomethyl)-N2-(2,2,2-trifluoro-1-phenylethyl)-L-leucinamide; antiarthritic agent; osteoporosis and other bone loss disorders |
08/07/2008 | US20080188504 Process for Preparing Pure Amorphous Rosuvastatin Calcuim |
08/07/2008 | US20080188501 retrovirus inhibor; anticarcinogenic, antidiabetic agent, immunosuppressant, autoimmune diseases; 2-{6-[3(R)-Amino-piperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl}-4-fluoro-benzonitrile; type 2 diabetes mellitus, impaired glucose tolerance, obesity, multiple sclerosis |
08/07/2008 | US20080188499 catecholpyrazine analogs, e.g. 2-[2-(5-nitro-2-furyl)vinyl]-4-[2-(3,4-dihydroxyphenyl)ethylamino]quinazoline; inhibitors of bacterial lipid A biosynthesis; antibiotic and bactericide; sterilization agent and antiseptic |
08/07/2008 | US20080188491 Modulation of pathogenicity |
08/07/2008 | US20080188490 e.g. 1-(3-Chloro-phenylethynyl)-3-(3,4-difluoro-phenylamino)-cyclohexanol; metabotropic glutamate receptors modulator/antagonist; |
08/07/2008 | US20080188468 Substituted Para-Trifluoromethyl Phenylate Compounds And Its Preparation And Use Thereof |
08/07/2008 | US20080188454 angiogenesis and/or cell proliferation, carcinoma, myeloid leukemia, endometriosis; inhibitors of the receptor protein tyrosine kinase; N3-(3-cyclopentyl-1,2,3,4,5,6-hexahydrobenzo[d]azocin-8-yl)-1-(6-fluoroquinazolin-4-yl)-1H-1,2,4-triazole-3,5-diamine |
08/07/2008 | US20080188451 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol1yl)-3-(trifluoromethyl)phenyl]benzamide or an N-oxide or salts; anticarcinogenic agent (leukaemia) |
08/07/2008 | US20080187978 Anti-inflammatory medicaments |
08/07/2008 | US20080187575 Pyrimidine Derivatives |
08/07/2008 | CA2702647A1 Thiopyrimidine-based compounds and uses thereof |
08/07/2008 | CA2677058A1 Polymorphs of 3-(e)-2-{2-[6-(2-cyanophenoxy) pyrimidin-4-yloxy] phenyl}-3-methoxyacrylate |
08/07/2008 | CA2676984A1 Compounds for the prevention and treatment of cardiovascular diseases |
08/06/2008 | EP1953160A1 Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with a cyclic amino group as CRF antagonists |
08/06/2008 | EP1953152A1 Process for preparing quinazoline RHO-kinase inhibitors and intermediates thereof |
08/06/2008 | EP1953148A1 Heterocyclic amide compound and use thereof |
08/06/2008 | EP1951686A1 Quinazoline derivatives as a multiplex inhibitor and method for the preparation thereof |
08/06/2008 | EP1951685A1 Novel quinazoline derivatives and their medical use |
08/06/2008 | EP1951684A1 Bi-aryl meta-pyrimidine inhibitors of kinases |
08/06/2008 | EP1951683A1 Pyrimidine derivatives for the treatment of cancer |
08/06/2008 | EP1951682A1 Novel 2-aminopyrimidinone or 2-aminopyridinone derivatives and their use |
08/06/2008 | EP1951681A1 Novel 2-aminopyrimidine derivatives and their use |
08/06/2008 | EP1951680A1 Novel 2-aminopyrimidinone derivatives and their use |
08/06/2008 | EP1439169B1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor |
08/06/2008 | EP1236712B1 Amidinophenylpyruvic acid derivative |
08/06/2008 | CN101238110A Heterocyclic compounds as agonists for the thyroid receptor |
08/06/2008 | CN101235018A Modified method for preparing (1,4,5,6-tetrahydro-2-pyrimidyl)thiourea or salts thereof |
08/06/2008 | CN100408567C Benzothiadiazepine derivatives, processes for their preparation and pharmaceutical compositions containing them |
08/05/2008 | US7407963 Cyclopropane CGRP antagonists, medicaments containing these compounds, and method for the production thereof |
08/05/2008 | US7407914 Herbicide composition |
08/05/2008 | US7407648 Protecting human and animal hair or skin from UV radiation by applying a 4,4-disubstituted -1,3-butadienylamine; 4,4-substituents may be the same or different and are cyano, ester, sec. or tert. amide, ketone and/or sulfone, e.g., 4,4-bis(hexyloxycarbonyl)-N,N-diethyl-1,3-butadienylamine |
07/31/2008 | WO2008089933A2 Benzoquinazole derivatives |
07/31/2008 | WO2008073687A3 Compounds and compositions as protein kinase inhibitors |
07/31/2008 | WO2008049645A3 Hydrates of erlotinib hydrochloride |
07/31/2008 | US20080182993 chemical intermediate is 4-(3,5-bi (1,1- dimethylethyl-4-hydroxyphenyl)-N-methyl-2-thiazolemethylamine |
07/31/2008 | US20080182985 Antitumor agents; preparing a quinazoline compound |
07/31/2008 | US20080182864 2-(1-Aroylaminoalkyl)-3-(alkylaryl)-7-(halo- or cyano)quinazolinone derivatives, e.g., 2-[1'-(N,N-dimethylethylenediamino)propyl]-3-benzylquinazolin-4-one; mitotic kinesin spindle protein inhibitors; disrupting mitosis; modulating mitotic spindle formation; restenosis |
07/31/2008 | US20080182860 Pyrimidine Compounds as Purine Receptor Antagonist |
07/31/2008 | US20080182850 3-(heteroaryl)alanine derivatives-inhibitors of leukocyte adhesion mediated by vla-4 |
07/31/2008 | US20080182846 Preventives or remedies for Alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound |
07/31/2008 | US20080182838 (5-{5-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]pyrazin-2-yl}-2H-tetrazol-2-yl)acetic acid; metabolic disorders,antidiabetic, hypoglycemic agent; obesity, insulin resistance, liver steatosis, atherosclerosis, neurological disease, dyslipidemia, hyperlipidemia, low HDL, and high LDL |
07/31/2008 | US20080182837 New chemical compounds |
07/31/2008 | CA2674921A1 Benzoquinazoline derivatives |
07/30/2008 | EP1950212A1 Polycyclic carbamoylpyridone derivative having inhibitory activity on hiv integrase |
07/30/2008 | EP1949896A2 Linear dicationic terphenyls and their aza analogues as antiparasitic agents |
07/30/2008 | EP1948621A1 Hiv integrase inhibitors |
07/30/2008 | EP1948620A2 Dihydrogen phosphate salt of a prostaglandin d2 receptor antagonist |
07/30/2008 | EP1948619A2 6-vinyl pyrimidine and pyrimidinone derivatives and the use thereof |
07/30/2008 | EP1948618A1 Crystalline rosuvastatin calcium |
07/30/2008 | EP1948617A2 Pyrimidinones as casein kinase ii (ck2) modulators |
07/30/2008 | EP1747204B1 Tri-substituted ureas as cytokine inhibitors |
07/30/2008 | EP1737462B1 Pyrimidines with tie2 (tek) activity |
07/30/2008 | CN101233131A Macrocyclic inhibitors of hepatitis c virus |