Patents
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Patents for C07D 239 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings (42,619)
11/2008
11/11/2008US7449456 signal transducer and activator of transcription-6 inhibitors; asthma, COPD, respiratory, inflammatory and allergic diseases; compounds have less suppressive effect on immunological functions; 4-[(2,5 -difluorobenzyl) amino]-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5 -carboxamide
11/06/2008WO2008133955A1 6-phenylpyrimidinones as pim modulators
11/06/2008WO2008133273A1 Pharmaceutical composition for treatment of alzheimer's disease
11/06/2008WO2008133155A1 Bicyclic heterocyclic compound
11/06/2008WO2008132138A1 Derivatives of 4,6-disubstituted aminopyrimidines
11/06/2008WO2008113881B1 Compound that is a dual inhibitor of enzymes pde7 and/or pde4, pharmaceutical compositions and uses thereof
11/06/2008WO2008112317A3 Triol form of rosuvastatin
11/06/2008WO2008078196A3 Substituted heteroaryl pyridopyrimidone derivatives
11/06/2008WO2007146553A3 N-[2-[[(diaminomethylene)amino]oxy]ethyl]-3-[(2,2-difluoro-2-phenylethyl)amino]-6-methyl-2-oxo-1(2h)-pyrazineacetamide
11/06/2008US20080275073 pharmaceutically acceptable salt selected from succinate, D-glucoronate, L-glucoronate, acetate, oxalate, proprionate, maleate, benzoate and citrate; protein kinase inhibitor; antitumorigenesis and anticell proliferation
11/06/2008US20080275069 3,8-dimethyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-4(3H)-quinazolinone; 6-chloro-3-methyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]pyrido[3,4-d]-pyrimidin-4(3H)-one; 2-[4-(1-cyclopentyl-4-piperidinyloxy)phenyl]-3-methylpyrido[2,3-d]-pyrimidin-4(3H)-one; treats metabolic, nervous system, vascular disorders
11/06/2008US20080275067 5-methyl-3-phenyl-2-[1-(9H-purin-6-ylamino)-propyl]-3H-quinazolin-4-one; 3-(4-fluoro-phenyl)-5-methyl-2-[1-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-ethyl]-3H-quinazolin-4-one; bone-resorption disorder or a cancer of a hematopoietic origin; disorders in which PI3K plays a role in leukocyte function
11/06/2008US20080275063 C-{4-[6-(2-Ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-N-propyl-methanesulfonamide; antiinflammatories, antiproliferatives, analgesics; cardiovascular disorders, neurodegenerative diseases; immunotherapy
11/06/2008US20080275062 Benzamide rho-kinase (ROCK-1) inhibitors; N-benzyl-4-(4-pyridinyl)benzamide
11/06/2008US20080275031 Inhibitors of C-FMS Kinase
11/06/2008US20080275029 Compounds for Treating Protein-Kinase Mediated Disorders
11/06/2008US20080275022 Substituted Quinazolones as Anti-Cancer Agents
11/06/2008US20080275004 N-Substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase
11/06/2008CA2685106A1 6-phenylpyrimidinones as pim modulators
11/05/2008EP1988164A1 Method of testing sensitivity of solid cancer against tyrosine kinase inhibitor and test kit therefor
11/05/2008EP1987831A1 Compounds effecting glucokinase
11/05/2008EP1987012A1 Reduction of 5-(aryl-diazenyl)-4,6-dihalo-pyrimidine
11/05/2008EP1987011A1 2-substituted pyrimidines and their use as pesticides
11/05/2008EP1987004A2 Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors
11/05/2008EP1987003A1 Pyridine-2-carboxamide derivatives
11/05/2008EP1986646A1 Novel azacycly-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
11/05/2008EP1713781B1 Quinazoline derivatives
11/05/2008EP1663970B1 Matrix metalloproteinase inhibitors
11/05/2008EP1465876B1 Long chain fatty alcohol substituents in antineoplastic agents
11/05/2008EP1324970B1 Retinoids for the treatment of emphysema
11/05/2008EP1296973B1 Guanidine derivatives of quinazoline for use in the treatment of autoimmune diseases
11/05/2008EP1053227B1 Ppar-gamma modulators
11/05/2008CN101300235A Diaminopyrimidines as P2X3 and P2X2/3 modulators
11/05/2008CN101300234A Compounds and compositions for protein kinase inhbitors
11/05/2008CN100430405C Processes for preparing calcium salt forms of statins
11/05/2008CN100430052C Cathepsin cysteine protease inhibitors
11/04/2008US7446210 Factor Xa compounds
11/04/2008US7446129 Suitable benzylation chemistry is to extract a hydrogen from a PDE4 inhibitor, preferably with a base, then react resulting nucleophilic PDE4 inhibitor with benzylating agent, e.g., benzyl bromide; no emetogenic side effects
11/04/2008US7446109 Carbonylamino-derivatives as novel inhibitors of histone deacetylase
11/04/2008US7446108 Tri-and tetraaza-acenaphthylen derivatives as CRF receptor antagonists
11/04/2008US7446104 Histamine receptor antagonists; 4-[3-(4-Piperidin-1-yl-but-1-ynyl)-benzyl]-thiomorpholine; antiallergens, antihistamines, antiepileptic agents; asthma, alzheimer's disease, narcolepsy, motion sickness, attention deficit disorder, schizophrenia
10/2008
10/30/2008WO2008131276A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
10/30/2008WO2008129951A1 Novel pyrimidine compound having dibenzylamine structure, and medicine comprising the compound
10/30/2008WO2008129380A1 Sulfonyl amide derivatives for the treatment of abnormal cell growth
10/30/2008WO2008129080A1 4, 6-disubstituted aminopyrimidine derivatives as inhibitors of protein kinases
10/30/2008WO2008129071A1 Inhibitors of protein kinases
10/30/2008WO2008129070A1 Inhibitors of protein kinases
10/30/2008WO2008129069A1 Inhibitors of protein kinases
10/30/2008WO2008106692B1 Pim kinase inhibitors and methods of their use
10/30/2008WO2008088727A3 Endothelin receptor antagonists
10/30/2008WO2008061112A3 Pharmaceutical compounds as inhibitors of cell proliferation and the use thereof
10/30/2008WO2008021049A9 Crystalline antifungal compounds
10/30/2008WO2008013987A3 N-alkyl substituted piperazinylmethylquinazolinones and azepanylmethylquinazolinones
10/30/2008US20080269487 6-{[1-(carbamoylmethyl)piperidin-4-yl]oxy}-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline; prevent, treat tumours which are sensitive to inhibition of erbB receptor tyrosine kinases
10/30/2008US20080269486 Reconfigurable molecules and molecular switches, sensors, and dyes employing the same
10/30/2008US20080269270 Triol form of rosuvastatin and synthesis of rosuvastatin
10/30/2008US20080269265 Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
10/30/2008US20080269264 Kinase inhibitor; amtiinflammatory agents; rheumatic diseases; osteoarthritis; asthma
10/30/2008US20080269262 Therameutin Modulators
10/30/2008US20080269255 Hypotensive agents; atherosclerosis; congestive heart failure; hypertrophy; cardiomyopathy; diabetic nephropathy; restenosis; cognition activator; Alzheimer's disease; anxiolytic agents
10/30/2008US20080269252 Use of Compounds Derived From Pyrimidinetrione as Acetyl Cholinesterase Inhibitors, Compositions Containing Said Derivatives, and the Uses Thereof
10/30/2008US20080269237 Histone deacetylase inhibitor; anticancer agents; antiproliferative agents; antitumor agents; psoriasis; piperazine compound containing a carbamic acid group
10/30/2008US20080269221 Antibacterial agents
10/30/2008US20080269217 Melanocortin-4 receptor binding compounds and methods of use thereof
10/30/2008US20080267914 Chemical Compounds
10/30/2008CA2683534A1 Novel pyrimidine compound having dibenzylamine structure and medicament comprising the same
10/30/2008CA2678639A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
10/29/2008EP1984344A2 Multicyclic amino acid derivatives and methods of their use
10/29/2008EP1984322A1 Benzamide and heteroarene derivatives
10/29/2008EP1687284B1 p-38 KINASE INHIBITORS
10/29/2008EP1263739B9 Crystalline salts of 7-¬4-(4-fluorophenyl)-6-isopropyl-2-¬methyl(methylsulfonyl)amino pyrimidin-5-yl -(3r,5s)-3,5-dihydroxyhept-6-enoic acid
10/29/2008CN101296907A Diaminopyrimidines as P2X3 and P2X2/3 modulators
10/29/2008CN101296897A PPAR modulating biaromatic compounds
10/29/2008CN100429204C Process for the preparation of 4- (3'-chloro-4'-fluoroanilino) -7-methoxy-6- (3-morpholinopropoxy) quinazoline
10/28/2008USRE40558 Peroxisome proliferator-activated receptors agonists/ antagonists; 2-methyl-6-[3-(quinolin-2-ylmethoxy)-propoxymethyl]-benzoic acid; eating diorders; physiological detrimental blood level of insulin, glucose, free fatty acids, or triglycerides; hyperlipemia; atherosclerosis; antidiabetic agent
10/28/2008US7442794 Stereoisomers ; reacting with Lewis acid; purification
10/28/2008US7442791 Aminoalkylamide substituted cyclohexyl derivatives
10/28/2008US7442705 HIV replication inhibiting pyrimidines and triazines
10/28/2008US7442704 Amide derivatives
10/28/2008US7442702 Prostaglandin agonists
10/28/2008US7442699 For treatment of rheumatoid arthritis, inflammatory or autoimmune condition, viral infection, cancer; 4-{[4-(4-chlorophenyl)pyrimidin-2-yl]amino}benzamide
10/28/2008US7442698 Substituted heterocyclic compounds and methods of use
10/28/2008CA2350968C Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural fungicide
10/28/2008CA2342102C Tan-1057 derivatives
10/23/2008WO2008128231A1 Pyrimidine derivatives
10/23/2008WO2008128072A2 Axl kinase inhibitors useful for the treatment of cancer or hyperproliferative disorders
10/23/2008WO2008127615A1 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
10/23/2008WO2008125891A2 Pyrimidinyl-piperazines useful as dopamine d3 /d2 receptor ligands
10/23/2008WO2008125867A2 Process for the preparation of gefitinib
10/23/2008WO2008125691A2 Ethers of naphtalene carboxylic acid amides as cancer cure
10/23/2008WO2008099210A3 Piperazine derivatives for treatment of ad and related conditions
10/23/2008US20080262010 dissolving with D-glucoronic acid in one or more solvents; and precipitating one crystalline polymorph as the D-glucoronate salt; kinase-inhibiting
10/23/2008US20080262009 dissolving an amount of compound and acetic acid as a mixture, in one or more solvents; and precipitating one crystalline polymorph of the compound as the acetate salt from the mixture
10/23/2008US20080262008 useful for inhibiting protein kinase activity; heating an amount of one crystalline polymorph of the compound of formula I as the pharmaceutically acceptable salt to a temperature that converts it to a different crystalline polymorph
10/23/2008US20080262007 replication inhibitors; improved ability to inhibit the replication of mutant strains, in particular strains which have become resistant to one or more known NNRTI drugs (Non Nucleoside Reverse Transcriptase Inhibitor drugs)
10/23/2008US20080262006 Selective endothelin type-a antagonists
10/23/2008US20080262005 Uracil-Type Gonadotropin-Releasing Hormone Receptor Antagonists and Methods Related Thereto
10/23/2008US20080261994 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
10/23/2008US20080261990 2-({4-[((2-Furylmethyl) {[6(4-methylphenyl)pyrimidin-4-yl]methyl}amino)methyl]phenyl}thio)-2-methylpropanoic acid; dyslipidemias, arteriosclerosis, coronary heart disease, thrombosis and metabolic syndrome
10/23/2008US20080261978 treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers; 1-(4-((pyridin-2-ylmethylamino)methyl)benzyl)-3-phenylurea
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