Patents
Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678)
09/1996
09/17/1996US5556982 Metal radionuclide labeled proteins for diagnosis and therapy
09/10/1996US5554602 Labelling of hormones with rhenium and tecnetium
08/1996
08/07/1996EP0724601A1 S 3n chelating compounds for the radiolabeling of ligands, anti-ligands or other proteins
08/07/1996EP0724480A1 Catalytic process
07/1996
07/25/1996WO1996022297A1 Non-nucleotide phosphorus ester oligomers
07/25/1996CA2210759A1 Non-nucleotide phosphorus ester oligomers
07/24/1996CN1127259A Peptides
07/16/1996US5536443 Duterium containing compounds foor electrooptical apparatus
07/11/1996WO1996020940A1 A novel radioisotope labelled compound, a mixture comprising said compound and a method for its preparation
07/11/1996WO1996020928A1 Piperidine-based sigma receptor ligands
07/11/1996WO1996020913A1 Novel trienoic retinoid compounds and methods
07/11/1996CA2206954A1 A novel radioisotope labelled compound, a mixture comprising said compound and a method for its preparation
07/09/1996US5534531 Anticancer agents
07/03/1996CN1125905A 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
06/1996
06/20/1996WO1996018650A1 Novel receptor
06/20/1996CA2207921A1 Novel receptor
06/05/1996EP0714911A2 Somastotatin analogs containing chelating groups and their radiolabeled compositions
06/04/1996US5523437 Useful in asymmetric synthesis reactions
05/1996
05/29/1996EP0713513A1 Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes
05/28/1996CA2078996C A bifunctional dtpa-type ligand
05/23/1996WO1996015086A1 Production of 11c-methyl iodide
05/22/1996EP0712315A1 Radiometal complexes that localise in hypoxic tissue
05/17/1996WO1996014277A1 Synthesis of 35s-labeled oligonucleotides with 3h-1,2-benzodithiol-3-1,1-dioxide
05/15/1996EP0711300A1 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
05/15/1996CN1122577A Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
05/14/1996US5516940 Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical
05/08/1996EP0710228A1 Hydrazino-type radionuclide chelators having an n 3?s configuration
05/08/1996CN1122132A Ligands and metal complexes thereof
05/01/1996EP0708765A1 Substituted piperazinylcamphor derivatives as oxytocin antagonists
04/1996
04/30/1996US5512675 Methods for preparing porphyrin-like compounds
04/23/1996US5510522 Synthesis of N-formyl-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine ethyl ester and its regioselective radiofluorodestannylation to 6- 18 F!fluoro-1-dopa
04/16/1996US5508456 Reducing alkyl ester with carrier-free lithium aluminum tritide, oxidizing ditritium alcohol to monotritium aldehyde, condensing with carbanion equivalent to form mixture of retinoid ester stereoisomers
04/09/1996US5506345 Antihypoxic agents
04/03/1996EP0515670B1 Hexadentate ligands useful in radiographic imaging agents
03/1996
03/26/1996US5502255 Substituted guanidines having high binding to the sigma receptor and the use thereof
03/12/1996US5498722 Hypotensives
03/12/1996US5498618 4-amino-N-(4-methyl-4-piperidinyl)-2-methoxybenzamides for treating smooth muscle contraction disorders
02/1996
02/28/1996EP0697894A1 Dopamine d-3 and serotonin (5-ht 1a?) receptor ligands and imaging agents
02/27/1996US5494654 Radiolabelled compound formulations
02/20/1996US5492111 Method of elimination of volatile degradation products of sevoflurane during anesthesia
02/15/1996WO1996004288A1 Glycine receptor antagonist pharmacophore
02/14/1996EP0696207A1 Use of cyclopentadienylcarbonyl transition metal carboxylic acids and their derivatives for labelling proteins
02/08/1996WO1996003124A1 Dynemicin analogs
02/01/1996WO1996002500A1 Technetium-sulphonamide complexes, their use, pharmaceutical agents containing them, and process for producing the complexes and agents
02/01/1996CA2194561A1 Technetium-sulphonamide complexes, their use, pharmaceutical agents containing them, and process for producing the complexes and agents
01/1996
01/30/1996US5488126 Amino acid compounds for metal chelates
01/24/1996EP0693467A1 Process for the preparation of radiolabeled meta-halobenzylguanidine
01/24/1996EP0692982A1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS
01/24/1996EP0692976A1 Chelating agents of the type xn 1?s 1?o 1? for radioactive isotopes, metal complexes thereof, and their use in diagnosis and therapy
01/18/1996DE4425781A1 Technetium-Sulfonamid-Komplexe, deren Verwendung, diese enthaltende pharmazeutische Mittel, sowie Verfahren zur Herstellung der Komplexe und Mittel Technetium-sulfonamide complexes, their use, pharmaceutical compositions containing them, and processes for producing the complexes and agents
01/10/1996EP0594837B1 Radiolabelled compound formulations
12/1995
12/27/1995EP0688313A1 Ligands and metal complexes thereof
12/26/1995US5478863 Substituted guanidines having high binding to the sigma receptor and the use thereof
12/21/1995WO1995034315A1 Radiolabeled annexin-galactose conjugates
12/14/1995WO1995033495A1 Thiolation of proteins for radionuclide-based radioimmunodetection and radioimmunotherapy
12/14/1995WO1995026325A3 Enhancement of the efficacy of drugs by deuteration
12/12/1995US5474756 Chelate compound of a paramagnetic ion of lanthanide element
12/12/1995US5474707 Cyclic hydrocarbon derivative and liquid crystal composition containing the same
11/1995
11/30/1995WO1995032192A1 Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
11/23/1995WO1995031221A1 Somatostatin binding peptide-metal chelate conjugates
11/22/1995EP0682649A1 Deuterated sevoflurane as an inhalational anesthetic
11/15/1995EP0551434B1 High affinity tamoxifen derivatives and uses thereof
11/09/1995WO1995029925A1 Thioether compounds for use in preparing bifunctional chelating agents for therapeutic radiopharmaceuticals
11/09/1995WO1995029669A2 Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical
11/09/1995CA2188569A1 Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical
11/09/1995CA2188565A1 Thioether compounds for use in preparing bifunctional chelating agents for therapeutic radiopharmaceuticals
11/02/1995WO1995029180A1 Porphocyanine and cnc-expanded porphyrins
10/1995
10/31/1995US5462725 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
10/19/1995WO1995027701A1 Metal-containing steroid mimics and ligands useful in the preparation thereof
10/05/1995WO1995026325A2 Enhancement of the efficacy of drugs by deuteration
10/05/1995CA2186371A1 Enhancement of the efficacy of dihydropyridines by deuteration
10/04/1995EP0674530A1 Polyhydric phenol compounds
09/1995
09/20/1995EP0672673A1 Non-cyclic chelating agents based on aminodialkylphosphoros oxides for the preparation of technetium or rhenium complexes
09/20/1995EP0429644B1 Chelating agents for attaching metal ions to proteins
09/16/1995CA2144588A1 Acyclic chelating agents based on aminodialkylphosphoric oxides for the preparation of technetium or rhenium complexes
09/12/1995US5449808 Method for converting amides to nitriles and nitriles to amides
08/1995
08/29/1995US5446147 Imaging agent
08/22/1995US5443815 Technetium-99m labeled peptides for imaging
08/16/1995EP0666859A1 Wavelength-specific photosensitive porphacyanine and expanded porphyrin-like compounds and methods for preparation and use thereof
08/03/1995WO1995020580A1 Macrocyclic octaaza compounds
08/03/1995DE4403039A1 Oktaazamakrocyclen, deren Metallkomplexe, Verfahren zu deren Herstellung, diese Komplexe enthaltende Mittel sowie deren Verwendung in Diagnostik und Therapie Oktaazamakrocyclen, their metal complexes, to processes for their preparation, agents containing these complexes and their use in diagnostics and therapy
07/1995
07/26/1995EP0663900A1 Metal-oxime chelates for use as radiopharmaceutical agents
07/20/1995WO1995019338A1 Ligands and metal complexes thereof
07/20/1995CA2156605A1 Ligands and metal complexes thereof
07/18/1995US5434287 Bifunctional DTPA-type ligand
07/13/1995WO1995018668A1 Process for separating carrier-free radionuclides from target liquids, its use and arrangement therefor
07/13/1995DE19500428A1 Sepn. of carrier-free radionuclides from target liquids
07/12/1995EP0662001A1 Multifunctional ligands for potential use in the design of therapeutic or diagnostic radiopharmaceutical imaging agents
07/11/1995US5431900 Ester-substituted diaminedithiols and radiolabeled complexes thereof
07/05/1995EP0661267A1 Chelating agent for attaching metal ions to proteins
06/1995
06/28/1995EP0470965B1 Preparation of rhenium phosphonate therapeutic agents
06/27/1995US5428139 Anticarcinogenic agents
06/06/1995US5422354 Quinuclidine derivatives
05/1995
05/30/1995US5420321 Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes
05/16/1995US5416016 Method for enhancing transmembrane transport of exogenous molecules
05/03/1995EP0650475A1 4-amino-n --(4-methyl-4-piperidinyl)-2-methoxybenzamides
05/03/1995EP0650372A1 Compounds for cancer imaging and therapy
05/03/1995EP0403544B1 Method of making radioiodinated pyrimidine
04/1995
04/27/1995WO1995011217A1 Isotopically-labeled retinoids, their production and use
04/27/1995WO1995011080A1 Catalytic process
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