Patents
Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678)
01/1991
01/24/1991WO1990014881A3 Chelating agents for attaching metal ions to proteins
01/23/1991EP0409740A1 Compound labelled with tritium, its preparation and use, especially in locating retinoid nuclear receptors
12/1990
12/27/1990WO1990015626A1 Methods for technetium/rhenium labelling of proteins
12/27/1990EP0403524A1 Preparation of nitruro compounds usable as radio-pharmaceutical products.
12/19/1990EP0403225A2 Methods for technetium/rhenium labelling of proteins
12/13/1990WO1990014881A2 Chelating agents for attaching metal ions to proteins
12/13/1990CA2033086A1 Chelating agents for attaching metal ions to proteins
11/1990
11/07/1990CN1046739A Macrocyclic aminophosphonic acid complexes, their preparation formulations and use
11/03/1990WO1990013530A1 Preparation of rhenium phosphonate therapeutic agents
11/03/1990CA2064063A1 Preparation of rhenium phosphonate therapeutic agents
11/01/1990WO1990009170A3 Agents for diagnosing and treating melanomas, aromatic halogenated derivatives usable as such agents and their preparation
10/1990
10/30/1990US4967021 Mixing with basic aqueous solution containing deuterium oxide in presence of phase transfer agent
10/30/1990US4966999 Phenolic hydrazides, hydrazines and amines; antibody conju-gates for diagnosis and therapy
10/23/1990US4965392 Diagnosis, radiotherapy of tumors
10/23/1990US4965391 Tumor specific
10/18/1990WO1990012096A1 Method for enhancing transmembrane transport of exogenous molecules
10/03/1990CA2013580A1 Method for enhancing transmembrane transport of exogenous molecules
09/1990
09/02/1990CA2011217A1 Preparation and use of triphenyl methanethiol-35s
08/1990
08/23/1990WO1990009170A2 Agents for diagnosing and treating melanomas, aromatic halogenated derivatives usable as such agents and their preparation
07/1990
07/31/1990US4945162 Novel radioactive propyl 2-iodospiroperidol and processes for the preparation thereof
07/17/1990US4942231 Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound
07/03/1990CA1271195A1 Ester-substituted diaminedithiols and radiolabeled complexes thereof
06/1990
06/28/1990WO1990006776A1 Macrocyclic aminophosphonic acid complexes, their preparation, formulations and use
06/27/1990EP0375376A2 Macrocyclic aminophosphonic acid complexes, their preparation, formulations and use
06/05/1990CA1269990A1 Thyronine derivatives
05/1990
05/30/1990CN1042536A Chelants possessing ortho ligating functionality and complexes thereof
05/09/1990EP0367223A2 Chelants possessing ortho ligating functionality and complexes thereof
05/01/1990CA1268596A1 Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents
04/1990
04/17/1990CA1267899A1 Compounds for site-enhanced delivery of radionuclides and uses thereof
03/1990
03/21/1990EP0359621A1 Compound labelled with tritium, its preparation and use, especially in the determination of the affinity of retinoids for their nuclear receptors and their cytosolic binding protein
03/20/1990CA1266864A1 Radiopharmaceuticals and chelating agents useful in their preparation
03/07/1990EP0357244A2 Method for converting nitriles to amides and amides to nitriles
02/1990
02/13/1990CA1265814A1 Process for the production of deuterated acrylic acid or deuterated methacrylic acid
02/06/1990US4898855 Treating osteoporosis and antiinflammatory agent
01/1990
01/09/1990CA1264330A1 Process for the production of deuterated methyl acrylate or deuterated methyl methacrylate
12/1989
12/27/1989EP0348261A1 Radiohalogenated compounds for site specific labeling
12/14/1989WO1989011876A1 Radiohalogenated compounds for site specific labeling
12/06/1989EP0345153A1 Affinity markers for hormonal steroid receptors, their use in hormonoradio therapy and as imaging agents of hormone-dependent cancers
12/06/1989EP0344816A1 Iodine-labelled pyrethrinoids, process and intermediates for their preparation and their use in radioimmuno assays
12/05/1989US4885363 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
12/05/1989US4885152 Radioactive benzodiazepine derivatives
12/05/1989US4885100 Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes
11/1989
11/14/1989US4880941 Trittum labelled compound, its preparation and its use in the determination of the affinity of retinoids for their cellular receptor
11/07/1989CA1262738A1 Method of isolating radioactive perrehnate or pertechnetate from an aqueous solution
10/1989
10/24/1989US4876081 Coupling to proteins, polypeptids; diagnostic and therapy compounds
10/19/1989WO1989008657A3 Preparation of nitruro compounds usable as radio-pharmaceutical products
10/17/1989US4874890 Direct substitution from heavy water or deuterium gas in presence of platinum group catalyst
10/17/1989US4874780 Anticancer compounds
09/1989
09/21/1989WO1989008657A2 Preparation of nitruro compounds usable as radio-pharmaceutical products
09/12/1989US4865994 Reacting 2-anilino-s-thiazolinone modified amino acid with amino compound labeled with radioactive isotope
08/1989
08/10/1989WO1989007106A1 Method of making radioiodinated pyrimidine
08/09/1989CN1034545A Metal-radionuclide-labeled protoins and glycoproteins for diagnosis and therapy
07/1989
07/26/1989EP0325559A2 Process for the preparation of complex compounds
07/25/1989US4851520 Method of making radioiodinated pyrimidine nucleoside or nucleotide
07/18/1989US4849207 Porphyrin derivatives
06/1989
06/27/1989US4842845 Radioactive metal chelates for dipyridoxyl phosphate
05/1989
05/30/1989CA1254901A1 Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes
05/10/1989EP0315188A2 Methods and materials for the preparation of metal labelled antibody solutions
04/1989
04/26/1989EP0313291A1 Radioactive benzodiazepine derivative and processes for producing the same
04/12/1989EP0310645A1 Compounds useful particularly for radiotherapy or imaging of cancer.
03/1989
03/23/1989WO1989002433A1 Tris(isonitrile)copper(i) adducts for preparing radionuclide complexes
03/22/1989EP0307786A2 Deuterated cholecalciferol derivatives, their preparation and their pharmaceutical use
03/21/1989US4814484 Radioimmunoassay
03/15/1989EP0307179A2 Mitomycins and processes for their preparation
03/01/1989EP0305320A2 Multinucleic substituted complexants, complexes and complex salts, process for their preparation and pharmaceutical agents containing them
03/01/1989EP0304780A1 Process for labelling substances with technetium or rhenium
02/1989
02/08/1989EP0302175A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
02/01/1989CN1030748A Vinyl substituted radiohalogen conjugates for protein labeling
01/1989
01/25/1989EP0300431A2 Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides
01/25/1989CN1030572A (methyl) acrylic acid ester
12/1988
12/27/1988US4794178 Carrier-free
12/01/1988WO1988007986A3 Compounds useful particularly for radiotherapy or imaging of cancer
11/1988
11/30/1988EP0292689A2 Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs
11/17/1988WO1988008720A1 Preparation of tc-99m radiopharmaceuticals
11/17/1988EP0291281A1 Preparation of Tc-99m Radiopharmaceuticals
11/09/1988EP0290041A2 Radioactive metal chelates of dipyridoxyl phosphate
11/02/1988EP0289187A2 Vinyl substituted radiohalogen conjugates for protein labeling
10/1988
10/26/1988EP0287909A1 Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor
10/20/1988WO1988007986A2 Compounds useful particularly for radiotherapy or imaging of cancer
10/19/1988EP0286898A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/18/1988US4778672 Method of isolating radioactive perrhenate or pertechnetate from an aqueous solution
10/12/1988EP0285950A2 A drug delivery conjugate
10/05/1988EP0285058A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/05/1988EP0285057A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
09/1988
09/28/1988EP0284071A2 Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy
09/21/1988EP0283139A2 Anticancer compounds
08/1988
08/31/1988EP0280597A1 Peroxide compounds containing the isotope o-17
08/24/1988EP0279417A2 Ester-substituted diaminedithiols and radiolabeled complexes thereof
08/17/1988CN88100364A Process for preparing deuterated organic compounds
08/03/1988EP0276675A2 Process for the preparation of deuterated organic compounds
07/1988
07/27/1988EP0275666A1 Radioactive propyl 2-iodospiroperidol and processes for the preparation thereof
05/1988
05/25/1988EP0268192A2 Esters of (meth)acrylic acid
05/11/1988EP0266910A2 Cationic complexes of Tc-99m
05/10/1988CA1236483A1 Labelling of organic molecules
04/1988
04/06/1988EP0263059A2 Complexes amides
04/05/1988US4735793 Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes
02/1988
02/03/1988EP0255471A1 1,4,7,10-Tetraazacyclododecane-derivatives
01/1988
01/19/1988CA1231715A1 Complexes of technetium-99m with alkylene amine oximes
11/1987
11/25/1987EP0246805A1 Process for preparation of deuterated methylene chloride
11/04/1987CN86108331A Radiohalogenated small molecules for protein labeling
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