Patents
Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678)
01/2007
01/03/2007CN1293064C Deuterated 3-piperidinopropiophenone and medicaments containing said compounds
12/2006
12/28/2006WO2006136846A1 Imaging 18f or 11c-labelled alkylthiophenyl guanidines
12/28/2006US20060292075 Labelled glutamine and lysine analogues
12/28/2006US20060292060 Radical trap in fluoridation of iodonium salt
12/28/2006DE102005028897A1 Anordnung und Verfahren zur Verarbeitung von chemischen Stoffen, Computerprogramm zur Steuerung einer solchen Anordnung sowie ein entsprechendes computerlesbares Speichermedium Apparatus and method for processing chemical substances, computer program for controlling such an arrangement and a corresponding computer-readable storage medium
12/28/2006CA2610744A1 Imaging 18f or 11c-labelled alkylthiophenyl guanidines
12/27/2006CN1886353A Methods of [11C]-radiolabelling phenothiazine and phenothiazine-like compounds
12/21/2006WO2006134474A2 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled acids by photo-induced free radical carbonylation under mild conditions using sulfoxides
12/21/2006WO2006134424A2 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled acids by photo-induced free radical carbonylation
12/21/2006WO2006133732A1 Process for synthesizing labelled compounds
12/20/2006EP1732865A1 Fluoridation method
12/20/2006EP1732864A1 Radiolabeled 3-¬3- (benzoyl-amido) benzyloxy| aspartic acid derivative and method of producing the same
12/14/2006WO2006131803A2 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled esters and acids by sensitized photo-induced free radical carbonylation
12/13/2006EP1730092A2 Methods to prepare carbon-isotope organohalides with high specific radioactivity from carbon-isotope monoxide
12/07/2006US20060275209 Methods of [11c]-radiolabelling phenothiazine and phenothiazine-like compounds
12/06/2006EP1727777A1 Radiosynthesis of acid chlorides
11/2006
11/30/2006WO2006127024A1 Reagents and methods for labeling terminal olefins
11/29/2006CN1869244A Production method of 15N stability isotop labeling L-arginine
11/23/2006US20060263886 Fluorous labeling for selective processing of biologically-derived samples
11/22/2006EP1723161A1 Radiolabeled compounds and compositions, their precursors and methods for their production
11/22/2006EP1723091A2 Synthesis of carbon-labeled perfluoroalkyl compounds
11/16/2006WO2006121035A1 Process for producing organic compound labeled with radioactive halogen
11/15/2006EP1720580A2 Improvement in the ligand protection for mercaptoacetyl triglycine
11/15/2006EP1633703A4 Isotopically labeled chemically stable reagents and process for the synthesis thereof
10/2006
10/26/2006US20060241318 Preparation of [18F]fluorine labeled aromatic L-amino acids
10/26/2006DE102005019452A1 New 18-fluorine-substituted 3'-deoxythymidine derivatives, useful in positron emission tomography, particularly for detection of brain tumors
10/24/2006US7126023 Method for deuteration of an inert methylene
10/10/2006CA2276284C Radioiodinated phospholipid ether analogs and methods of using the same
10/05/2006WO2006103509A2 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via ketene using diazo compounds and carbon-isotope monoxide
10/05/2006WO2006071138A8 Tritium-traced saxitoxin dihydrochloride and method for the production thereof
10/04/2006EP1707548A1 Method of deuteration using mixed catalyst
10/03/2006US7115249 producing radiolabelled 6-L-fluorodopa on support; deblocking, deprotecting; for use in positron emission tomography; kits
09/2006
09/28/2006WO2006100563A1 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide
09/28/2006WO2006100481A2 Preparations of 11c methyl iodide and of the radioligand 11c gb67
09/28/2006WO2005037853A3 Side chain deuterated amino acids and methods of use
09/27/2006EP0759786B1 Somatostatin binding peptide-metal chelate conjugates
09/26/2006US7112685 Labeled resiniferatoxin derivatives
09/26/2006US7112318 Phosphonium or quaternary ammonium salts labeled with 11C, 18F,76Br, or 123I; for positron emission tomography; capable of measuring mitochondrial surface potential; localize into dysfunctional mitochondria
09/21/2006WO2006072336A3 Radioactive metal complexes based on bispidine and derivatives thereof
09/19/2006US7108846 Methods for preparing perfluorinated [18f]-radiolabelled nitroimidazole derivatives for cellular hypoxia detection
09/19/2006US7108845 Methods of synthesis and use of radiolabelled platinum chemotherapeutic agents
09/14/2006US20060205967 Use of pamoic acid or one of its derivatives, or one of its analogues, for the preparation of a medicament for the treatment of diseases characterised by deposits of amyloid aggregates
09/14/2006US20060205953 Isotopically labeled chemically stable reagents and process for the synthesis thereof
09/14/2006DE19648155B4 Verfahren zur Deuterierung A method for deuteration
09/08/2006WO2006092902A1 Radioactive halogen-labeled phenyloxyaniline derivatives
09/08/2006CA2599321A1 Radioactive halogen-labeled phenyloxyaniline derivatives
09/06/2006EP1698350A1 Porphyrin-based compounds for tumor imaging and photodynamic therapy
09/06/2006EP1697280A1 Methods for carbon isotope labeling synthesis of ketones and amines by suzuki coupling reactions using carbon-isotope monoxide
09/06/2006EP1697279A1 Radical trap in fluoridation of iodinium salt
09/06/2006CN1829748A Heavy-hydrogenated norbornyl (meth)acrylates, process for producing them, polymers thereof and optical members
09/06/2006CN1829747A Heavy-hydrogenated (meth)acrylates, process for producing them, polymers thereof and optical members
08/2006
08/30/2006EP1694636A1 Methods for carbon isotope labeling synthesis by rhodium-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide
08/29/2006CA2153851C Process for the preparation of radiolabeled meta-halobenzylguanidine
08/23/2006EP1399401B1 Solid-phase electrophilic fluorination
08/17/2006WO2006051428A3 Use of [11c] carbon monoxide in labeling synthesis of 11c-labelled amides using photo-induced free radical carbonylation
08/16/2006EP1689675A2 Method and apparatus for synthesis of 11c| phosgen using concentrated 11c| carbon monoxide with uv light
08/10/2006WO2006082497A1 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled compounds by thermally induced free radical carbonylation
08/09/2006EP1688404A2 Kit comprising a device for the synthesis of 2-[18F]fluoro-2-deoxy-D-glucose (FDG)
08/09/2006EP1687643A1 Fluorous labeling for selective processing of biologically-derived samples
08/03/2006WO2006080202A1 Method for producing deuterium gas and catalytic deuteration method using deuterium gas obtained thereby
08/03/2006CA2596233A1 Method for producing deuterium gas and catalytic deuteration method using deuterium gas obtained thereby
08/02/2006CN1812816A Prosthetic groups attached to stannyl polymer in the synthesis of radiopharmaceuticals
07/2006
07/27/2006US20060165593 Tc and re labeler radioactive glycosylated octreotide derivatives
07/26/2006EP1683776A1 Process for producing radioactive-fluorine-labeled compound
07/18/2006CA2190727C Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
07/13/2006WO2006072336A2 Radioactive metal complexes based on bispidine and derivatives thereof
07/13/2006US20060154323 Method for obtaining dynamic and structural data pertaining to proteins and protein/ligand complexes
07/12/2006EP1678198A2 Side chain deuterated amino acids and methods of use
07/12/2006EP1678102A1 Method and apparatus for the use of [11c] carbon monixi de in labeling synthesis by photo-initiated carbonylation
07/06/2006WO2006071138A1 Tritium-traced saxitoxin dihydrochloride and method for the production thereof
07/06/2006DE102004022461B4 Metallkomplexe auf der Basis von Tetrathiol-Liganden und deren Anwendung in der nuklearmedizinischen Diagnostik und Endoradionuklidtherapie sowie Verfahren zur Herstellung der Metallkomplexe Metal complexes based on Tetrathiol ligands and their use in nuclear medical diagnosis and endoradionuclide therapy and methods for preparing the metal complexes
07/04/2006US7071231 Especially Type II diabetes; stimulating the kinase activity of the insulin receptor; activating the insulin receptor
06/2006
06/29/2006WO2006068015A1 Method of producing potassium [18f] fluoride and quaternary ammonium [18f] fluoride and method of producing radioactive fluorine-labeled organic compound by using the same
06/29/2006WO2006067376A2 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
06/29/2006DE19928911B4 Verfahren zur Herstellung von 3-0-Methyl-6-[18F]Fluor-DOPA, (3-0-Methyl-6-[18F]Fluor-L-4-hydroxyphenylalanin, 3-(2-[18F]Fluor-4-hydroxy-5-methoxy-phenyl)-2-amino-propansäure) Process for the preparation of 3-0-methyl-6- [18F] fluoro-DOPA, (3-0-methyl-6- [18F] fluoro-L-4-hydroxyphenylalanine, 3- (2- [18F] fluoro-4 -hydroxy-5-methoxy-phenyl) -2-amino-propanoic acid)
06/29/2006CA2817636A1 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
06/29/2006CA2589136A1 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
06/22/2006WO2006064349A1 Method for the use of [11c] carbon monoxide inlabeling synthesis of 11c-labelled esters by photo-induced free radical carbonylation
06/22/2006US20060135615 Deuterated catecholamine derivatives and medicaments comprising said compounds
06/22/2006US20060135414 Cyclosporine derivatives are disclosed which possess enhanced efficacy and reduced toxicity over naturally occurring and other presently known cyclosporins and cyclosporine derivatives. The cyclosporine derivatives of the present invention are produced by chemical and isotopic substitution
06/14/2006EP1667947A1 Methods of 11c -radiolabelling phenothiazine and pheno thiazine-like compounds
06/14/2006CN1788009A Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof
06/08/2006WO2005120584A3 Radiolabeled arylsulfonyl compounds and uses thereof
06/07/2006EP1666466A2 Mutilin derivatives and their use as Antimicrobials
06/07/2006EP1663915A1 Method for the production of [18f] fluoride-marked aromatic l-amino acids
06/07/2006EP1663868A2 Process for preparing radiolabelled compounds
06/06/2006US7057055 Process for preparing a deuterated or tritiated compound
06/01/2006WO2005014479A3 Process for preparing radiolabeled compounds
06/01/2006US20060116535 Method of deuteration
05/2006
05/26/2006WO2006053785A1 Radiolabelled quinoline-based ligands for the 5-ht6 receptor functionality
05/26/2006CA2588381A1 Radiolabelled quinoline-based ligands for the 5-ht6 receptor functionality
05/23/2006US7049289 Labelled glutamine and lysine analogues
05/18/2006US20060106219 making a fluoro radioactive material [18F]Fluorohaloalkanes radiotracer through halogenation, or solid phase synthesis; use in positron emission tomography (PET) studies
05/18/2006US20060104900 Polymer precursors of radiolabeled compounds, and methods of making and using the same
05/16/2006US7045642 Labeling using deuterium, tritium with catalyst
05/16/2006US7045606 Chelate compound containing ligand with steroids, enzymes, hapten and antibodies
05/04/2006WO2006045886A1 Continuous process for obtaining a product comprising at least one hydrogen isotope
05/02/2006US7037486 Labelled phosphoinositides and analogues
04/2006
04/20/2006WO2005054128A3 Method and apparatus for synthesis of [11c] phosgen using concentrated [11c] carbon monoxide with uv light
04/19/2006CN1251767C Kit for radiolabeling proteins with yttrium-90
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