Patents
Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678)
01/1993
01/27/1993EP0524639A2 Process for the labelling of substances with technetium or rhenium
01/13/1993EP0522918A1 Process for the preparation of sulfides and amino acids labelled with sulfur-35
01/07/1993WO1992019210A3 Serotinin reuptake inhibitors for s.p.e.c.t imaging
12/1992
12/10/1992WO1992021379A1 Radiolabeled metal-binding protein for the treatment of arthritis
12/09/1992EP0516873A1 A method and kit for protein labelling with 99 mTC
12/08/1992CA1311239C Porphyrin derivatives, and their production and use
11/1992
11/26/1992WO1992020674A1 1h-imidazol-1-yl-methyl benzofuran derivatives, with the imidazolyl moiety being substituted by a cycloalkyl group
11/25/1992EP0515313A2 Somatostatin analogues containing chelating groups and their radiolabeled compositions
11/19/1992EP0514198A1 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group
11/17/1992CA2068766A1 Benzofuran derivatives
11/12/1992WO1992019210A2 Serotinin reuptake inhibitors for s.p.e.c.t imaging
11/10/1992US5162231 Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
10/1992
10/21/1992EP0509161A1 Preparation of boronic acid derivatives
10/15/1992WO1992011040A3 99mtc(iii) myocardial imaging agents and method of use
10/13/1992US5154912 Nonradioactive labeled compounds for use in the medicine and biological fields
09/1992
09/22/1992US5149846 Deuterated analogs of 1,25-dihydroxycholecalciferol
09/21/1992CA2038663A1 Pancreatic imaging agents
09/17/1992WO1992015333A1 TECHNETIUM-99m LABELING OF PROTEINS
09/17/1992CA2104943A1 Technetium-99m labeling of proteins
09/10/1992DE4107088A1 Prepn. of L-(selenium-75)-seleno:methionine - by reaction of selenium-75 with methyl:lithium, followed by reaction with L-alpha-amino-gamma bromo:butyric acid
09/09/1992EP0502594A1 Chelates, their metal complexes as well as their use in diagnosis and therapy
09/08/1992CA2062483A1 Chelates, their metal complexes as well as their use in diagnosis and treatment
08/1992
08/22/1992WO1991018868A1 Substituted guanidines having high binding to the sigma receptor and the use thereof
08/20/1992WO1992013826A1 Compositions and method for soft tissue tumors
08/20/1992WO1992013572A1 TECHNETIUM-99m LABELED POLYPEPTIDES FOR IMAGING
08/15/1992WO1992014492A1 In situ synthesis of radiopharmaceuticals
08/15/1992CA2101642A1 In situ synthesis of radiopharmaceuticals
08/11/1992US5138039 Diagnosis, therapy
08/05/1992EP0497356A1 Compositions and method for soft tissue tumors
07/1992
07/28/1992US5133956 Radiolabeled metal-binding protein for the treatment of arthritis
07/14/1992CA1305160C Ether isonitriles and radiolabeled complexes thereof
07/07/1992US5128119 Methods for technetium/rhenium labeling of f(ab1)2 fragments
06/1992
06/30/1992CA1304364C Radioactive benzodiazepine derivative and processes for producing the same
06/23/1992US5124471 Radiolabeling proteins
06/23/1992US5124267 Complexing with antibody; mass spectrometry
06/22/1992WO1992011040A2 99mTc(III) MYOCARDIAL IMAGING AGENTS AND METHOD OF USE
06/22/1992CA2097081A1 Tc(iii)myocardial imaging agents and method of use
06/16/1992CA1303626C (meth)acrylate esters
06/15/1992WO1992010466A1 Hexadentate ligands useful in radiographic imaging agents
06/15/1992CA2076016A1 Hexadentate ligands useful in radiographic imaging agents
06/10/1992EP0310645B1 Compounds useful particularly for radiotherapy or imaging of cancer
06/02/1992US5118858 Triphenyl methanethiol-35S
06/02/1992CA1302403C Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor
05/1992
05/26/1992US5116573 Labelled vitamin d3 derivative and production process thereof
05/12/1992US5112595 99MTC(III) myocardial imaging agents and method of use
05/12/1992US5112594 Diaminoalkyldifuranones and phosphine ligands with technetium for imaging
05/12/1992CA1300602C Radiolabelling kit
04/1992
04/28/1992US5108921 Method for enhanced transmembrane transport of exogenous molecules
04/02/1992WO1992006068A1 High affinity tamoxifen derivatives and uses thereof
04/02/1992WO1992005154A1 Novel nitrogen-sulfur ligands useful in radiographic imaging agents
04/02/1992CA2092996A1 High affinity tamoxifen derivatives and uses thereof
03/1992
03/19/1992DE4029067A1 Verfahren zur herstellung der salze der 3,3-dideutero-2-fluoracrylsaeure und der trideutero-2-fluoracrylsaeure und deren verwendung A process for the preparation of the salts of 3,3-dideutero-2-fluoracrylsaeure and trideutero-2-fluoracrylsaeure and their use
03/17/1992US5096694 Compounds which are useful, in particular, for radiotherapy or imaging of cancer
03/14/1992WO1992005128A1 Process for producing 3,3-dideutero-2-fluoracrylic acid and trideutero-2-fluoracrylic acid salts and their use
03/14/1992CA2092689A1 Process for the preparation of the salts of 3,3-dideutero-2-fluoroacylic acid and of trideutero-2-fluoroacrylic acid and their use
03/03/1992CA1296715C 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecane and analogs
02/1992
02/25/1992US5091514 Antitumor, anticarcinogenic agents
02/11/1992US5087721 Radioiodinated phosphate esters
02/06/1992WO1992001673A1 Synthesis and uses of spin labelled ribonucleosides and ribonucleotides
02/05/1992CN1058405A 奎宁环衍生物 Quinuclidine derivatives
01/1992
01/24/1992WO1992001688A1 Quinuclidine derivatives
01/23/1992WO1992000982A1 Process for the preparation of transition metal nitrido complexes
01/23/1992WO1992000758A1 Method of preparing a radioactive rhenium complex solution
01/22/1992EP0466816A1 Method for enhancing transmembrane transport of exogenous molecules
01/21/1992US5082980 Medical diagnosis
01/14/1992US5081232 Nitrosyl moiety and ligands which confer target organ-seeking properties, heart visualizing agents
01/08/1992CN1057585A Ether isonitriles and radiolabeled complexes thereof
12/1991
12/31/1991CA1293733C Tritium-labelled compound, its means of preparation and its application, in particular in determining the affinity of retinoids for their cell receptors
12/27/1991EP0462546A2 Process for synthesis of 11C-labeled methyl iodide and apparatus
12/26/1991WO1991019978A1 Using 5,10,15,20-tetrakis(4-carboxyphenyl)porphine for detecting and treating lung cancers
12/26/1991WO1991019977A1 USING 5,10,15,20-TETRAKIS(r-CARBOXYPHENYL)PORPHINE FOR DETECTING AND TREATING LUNG CANCER
12/24/1991US5075337 Alpha-deuterated 2-alkylaminoacetamide derivatives having reduced toxicity for treatment of CNS disorders
12/19/1991WO1991019516A1 Metal-radionuclide complex comprising isonitrile ligands
12/19/1991CA2085364A1 Metal-radionuclide complex comprising isonitrile ligands
12/17/1991US5073361 Compound marked with tritium, its preparation and its use in the location of nuclear receptors of retinoids
12/04/1991EP0458886A1 Agents for diagnosing and treating melanomas, aromatic halogenated derivatives usable as such agents and their preparation.
11/1991
11/28/1991WO1991017999A1 METHOD FOR LABELLING SUBSTANCES CONTAINING AMINO GROUPS, INCLUDING CELLS SUCH AS BLOOD CELLS, WITH 99mTc AND KIT FOR CARRYING OUT THIS METHOD
10/1991
10/22/1991US5059412 Macrocyclic aminophosphonic acid complexes for the treatment of calcific tumors
10/18/1991WO1991016076A1 Method and kit for preparing technetium-99m complexes
10/18/1991CA2080685A1 Method and kit for preparing technetium-99m complexes
10/17/1991WO1991015858A1 Methods and agents for deuterium/tritium labeling
10/16/1991EP0451824A2 Chelating compounds and their use
09/1991
09/27/1991WO1991014459A1 A bifunctional dtpa-type ligand
09/24/1991US5051523 Transcomplexing a complex of a beta-dicarbonyl metal with a chelating agent
09/11/1991CN1013860B Ether isonitriles and radiolabeled complexes thereof
08/1991
08/27/1991US5043453 Using organolathanide complex catalyst
08/14/1991DE4012405C1 Radioisotope labelled oxiranyl carboxylic acid derivs. prodn. - by nucleophilic replacement of corresp. bromo or iodo substits. with radioactive alkali halide(s) in polar medium
08/13/1991US5039795 Preparation of boronic acid derivatives
08/06/1991CA1287357C Radioactive propyl 2-iodospiroperidol and processes for the preparationthereof
06/1991
06/25/1991US5026909 Method for preparing biologically active organic compound labelled with hydrogen isotope
06/18/1991US5024828 Iodine-labeled isomers and racemic mixtures for radioimmuno-assays of physiological fluids
06/13/1991WO1991008180A1 Deuterized 2,3,3-trihalogeno 2-fluoro 1-propanols, their preparation and use
06/04/1991US5021235 Reducing and complexing radioactive perrhenates with bone seeking ligands
06/04/1991US5021220 Kit for preparing radiodiagnostic examination compositions
04/1991
04/16/1991CA1283131C Preparation of deuterated methylene chloride
03/1991
03/20/1991EP0417870A2 Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy
03/12/1991CA2023595A1 Chelating agents for forming complexes with radioactive isotopes, metal complexes thereof and use thereof in diagnosis and therapy
03/06/1991CN1049649A Process for solid phase labelling of halogen substituted chemical and labelling reactor
02/1991
02/26/1991US4996312 Porphyrin derivatives, and their production and use
01/1991
01/29/1991US4988827 Ether isonitriles and radiolabeled complexes thereof
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