| Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678) |
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| 05/27/2009 | CN101443307A Method for preparing radioactive fluorine labeled organic compound |
| 05/26/2009 | US7538189 Cyclosporine derivatives are disclosed which possess enhanced efficacy and reduced toxicity over naturally occurring and other presently known cyclosporins and cyclosporine derivatives. The cyclosporine derivatives of the present invention are produced by chemical and isotopic substitution |
| 05/20/2009 | EP2059491A1 Method for the purification of radiolabelled compounds |
| 05/19/2009 | US7534814 Mutilin derivatives and their use as antibacterials |
| 05/07/2009 | WO2009057528A1 Kit for use in production of molecular probe for pet drug screening |
| 05/06/2009 | EP2054060A1 Fluorinated ligands for targeting peripheral benzodiazepine receptors |
| 04/30/2009 | WO2009055006A1 Deuterated darunavir |
| 04/30/2009 | WO2009054964A1 Alpha-aminoamide derivatives |
| 04/30/2009 | WO2009052970A2 Compounds for use in imaging, diagnosing, and/or treatment of diseases of the central nervous system or of tumors |
| 04/30/2009 | CA2703591A1 Deuterated darunavir |
| 04/30/2009 | CA2703080A1 Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors |
| 04/29/2009 | EP2053033A1 Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors |
| 04/23/2009 | WO2009032843A3 Deuterated ethambutols and their use |
| 04/21/2009 | US7521544 Photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides; carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography |
| 04/21/2009 | US7521421 Cyclosporine derivatives are disclosed which possess enhanced efficacy and reduced toxicity over naturally occurring and other presently known cyclosporins and cyclosporine derivatives. The cyclosporine derivatives of the present invention are produced by chemical and isotopic substitution |
| 04/16/2009 | WO2009015048A3 Microfluidic radiosynthesis of a radiolabeled compound using electrochemical trapping and release |
| 04/16/2009 | US20090098048 Radioactive tyrosine derivative, method for producing same, labeling agent for positron imaging and medical agent for assessing grade of malignancy of tumor respectively composed of radioactive tyrosine derivative, and method for detecting tumor |
| 04/15/2009 | EP2048140A1 Deuterated chemiluminescent 1,2-dioxetanes |
| 04/15/2009 | EP2046396A2 Methods and agents for preparing 18f-radiolabeled fluorinating agents |
| 04/15/2009 | EP1156835B1 Method for radiolabeling proteins with yttrium-90 |
| 04/15/2009 | CN101407543A Labelled glutamine and lysine analogues |
| 04/14/2009 | US7517990 Method for deuteration of a heterocyclic ring |
| 04/14/2009 | CA2380980C Mutilin derivatives and their use as antibacterials |
| 04/09/2009 | DE10346228B4 Herstellung von [18F]fluormarkierten aromatischen L-Aminosäuren Preparation of [18F] fluorine labeled aromatic L-amino acids |
| 04/02/2009 | WO2008124651A3 Nitro-imidazole hypoxia imaging agents |
| 04/01/2009 | EP1381396B1 Tc and re labeled radioactive glycosylated octreotide derivatives |
| 03/19/2009 | WO2009035959A2 Radiofluorination methods |
| 03/12/2009 | WO2009032843A2 Deuterated ethambutols and their use |
| 03/12/2009 | WO2009032723A1 Perfluoro macrocycles in 18f-labelling of macromolecules |
| 03/12/2009 | WO2008130924A4 Isotopically-labeled glycans |
| 03/11/2009 | EP2032525A1 Deuterated aminoglycidyl compounds |
| 03/11/2009 | EP2032512A1 Radiolabelled ligand for the glycine 1 transporter |
| 03/11/2009 | CN101384545A Deuterated catecholamine derivatives and medicaments comprising said compounds |
| 03/11/2009 | CN101381296A Method for synthesizing carbon nuclide (<11>C) labeled acetate |
| 03/11/2009 | CN101381295A Double label <13>C2-acetic acid preparation method |
| 03/10/2009 | CA2301046C 13c, 15n, 2h labeled proteins for nmr structure determinations and their preparation |
| 03/05/2009 | WO2009029633A1 Synthesis of [18f]-labelled alkyl mesylates using fluorous spe separation |
| 03/04/2009 | EP2029503A1 11c/18 f-labeled inhibitors of glycogen synthase kinase-3 |
| 03/04/2009 | EP1678102B1 Method and apparatus for the use of [11c] carbon monixi de in labeling synthesis by photo-initiated carbonylation |
| 02/26/2009 | WO2009001046A3 [11c]methoxy-radiolabelled 2,3',4,5'-tetramethylstilbene (tms) and its preparation and use |
| 02/26/2009 | WO2008155339A3 Labelling methods |
| 02/18/2009 | CN201195713Y Fluorine-18 nucleophilic reaction apparatus |
| 02/18/2009 | CN100462378C Heavy-hydrogenated (meth)acrylates, process for producing them, polymers thereof and optical members |
| 02/05/2009 | US20090036659 Method of deuterating benzyl-position in -o-benzyl group |
| 02/05/2009 | CA2695008A1 Substituted indoles |
| 02/04/2009 | CN101360698A Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity |
| 01/29/2009 | WO2009015048A2 Microfluidic radiosynthesis of a radiolabeled compound using electrochemical trapping and release |
| 01/29/2009 | WO2009014203A1 Method for producing (1,3,5/2,4,6)-1-fluoro-2,3,4,5,6-cyclohexanepentol |
| 01/29/2009 | WO2008130924A3 Isotopically-labeled glycans |
| 01/27/2009 | US7482498 Synthesis of a radioactive 18-fluorine isotope-labeled imaging compound using a positron emission tomograph or magnetic resonance; more flexible results by placing the anion exchange device partially in the measurement chamber to measure [18F]fluoride ions in the anion exchange device; efficiency |
| 01/21/2009 | EP2017359A2 Method for the elution of 18F fluoride trapped on an anion-exchange resin in a form suitable for efficient radiolabeling without any evaporation step |
| 01/21/2009 | EP2017258A1 Process for production of radioactive fluorine-labeled organic compound |
| 01/15/2009 | WO2008128306A8 Method for the preparation of reactive [18] f fluoride |
| 01/15/2009 | DE112007000484T5 Stabil isotopenmarkierte aliphatische Aminosäuren, Verfahren zum Einbringen von diesen in ein Zielprotein und Verfahren zur NMR-Konformationsanalyse von Proteinen Stable isotope-labeled aliphatic amino acids, methods for introducing these into a target protein, and NMR method for the conformation of proteins |
| 01/14/2009 | EP1742897B1 Novel 15o-labeled monosaccharide and producing method thereof |
| 01/08/2009 | WO2009005069A1 Method of deuteration using ruthenium catalyst |
| 01/08/2009 | WO2009004914A1 Pet probe having alkoxy group substituted by fluorine and hydroxy group |
| 01/08/2009 | WO2008040441A3 Silicon derivatives for pet imaging |
| 01/08/2009 | CA2699965A1 Pet probe having an alkoxy group substituted by fluorine and hydroxy group |
| 01/07/2009 | EP2011520A1 Kit for Radiolabeling Proteins with Yttrium-90 |
| 01/07/2009 | EP2010227A2 Radiofluorinated compounds and their preparation |
| 01/07/2009 | EP1009725B1 13c,15n,2h labeled proteins for nmr structure determinations and their preparation |
| 01/01/2009 | US20090005617 Synthesis of a radioactive 18-fluorine isotope-labeled imaging compound using a positron emission tomograph or magnetic resonance; more flexible results by placing the anion exchange device partially in the measurement chamber to measure [18F]fluoride ions in the anion exchange device; efficiency |
| 12/31/2008 | WO2009001046A2 [11c]methoxy-radiolabelled 2,3',4,5'-tetramethylstilbene (tms) and its preparation and use |
| 12/31/2008 | CN101336114A Radiolabelling method using polymers |
| 12/31/2008 | CN101333138A Device and process capable of simultaneously preparing three different <18>F radiopharmaceuticals |
| 12/30/2008 | CA2345710C Preparation of radiolabelled haloaromatics via polymer-bound intermediates |
| 12/24/2008 | WO2008155339A2 Labelling methods |
| 12/24/2008 | WO2008099203A3 Reactions of isotopically enriched elements of phosphorus, sulfur, selenium and tellurium |
| 12/24/2008 | CA2687974A1 Labelling methods |
| 12/04/2008 | WO2008146316A1 Purif ication procedure for the preparation of the radioactive tracer 3' -deoxy-3' - [18f] luorothymidine ( [18f] flt) |
| 12/04/2008 | CA2689275A1 Purification procedure for the preparation of the radioactive tracer 3'-deoxy-3'-[18f] fluorothymidine ([18f]flt) |
| 12/03/2008 | CN101316812A Precursor compound of radioactive halogen labeled organic compound |
| 11/27/2008 | US20080293812 Use of pamoic acid or one of its derivatives, or one of its analogues, for the preparation of a medicament for the treatment of diseases characterised by deposits of amyloid aggregates |
| 11/26/2008 | EP1995236A1 Tellurium (Te) precursors for making phase change memory materials |
| 11/20/2008 | WO2008141021A1 Deuterated derivatives of tetrahydrotriazolopyrazine compounds and their use as dpp-iv inhibitors |
| 11/20/2008 | WO2008140859A1 Deuterated venlafaxines and 0-desmetylvenlafaxines with serotoninergic and / or norepinephrinergic activity |
| 11/20/2008 | WO2008140616A2 Nucleophilic radiofluorination using microfabricated devices |
| 11/20/2008 | DE102007023256A1 Purifying fluoroalkyl- and fluoroacyl-compound, comprises providing solution of e.g. fluoroalkyl compound, leading this solution over first stationary phase, forwarding eluate over second stationary phase, washing and flowing from phase |
| 11/20/2008 | CA2680912A1 Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| 11/19/2008 | EP1991522A2 Deuterated catecholamine derivatives and medicaments comprising said compounds |
| 11/19/2008 | EP1651689A4 Heavy-hydrogenated norbornyl (meth)acrylates, process for producing them, polymers thereof and optical members |
| 11/19/2008 | EP1651688A4 Heavy-hydrogenated (meth)acrylates, process for producing them, polymers thereof and optical members |
| 11/13/2008 | WO2008137474A1 Morphinan compounds |
| 11/13/2008 | US20080279770 Metal Complexes Based on Tetrathiol Ligands and Their Use in Nuclear Medical Diagnostics and Endoradionuclide Therapy and Method For Producing Said Metal Complexes |
| 11/13/2008 | CA2685723A1 Morphinan compounds |
| 11/12/2008 | EP1990310A1 Method for the preparation of reactive 18F fluoride, and for the labeling of radiotracers, using a modified non-ionic solid support and without any evaporation step |
| 11/06/2008 | US20080274052 [18F]-fluorination for use making radiopharmaceuticals for Positron Emission Tomography (PET); reacting a compound of formula 18F-(Linker)-SH with an activated peptide |
| 11/05/2008 | EP1723091B1 Synthesis of carbon-labeled perfluoroalkyl compounds |
| 10/30/2008 | WO2008130924A2 Isotopically-labeled glycans |
| 10/30/2008 | WO2008128306A1 Method for the preparation of reactive [18] f fluoride |
| 10/29/2008 | EP1985624A2 Single step method of radiofluorination of biologically active compounds or biomolecules |
| 10/23/2008 | WO2008125617A2 18f-labelled folates |
| 10/23/2008 | WO2008125613A1 18f-labelled folates |
| 10/23/2008 | CA2670379A1 18f-labelled folates |
| 10/23/2008 | CA2670363A1 18f-labelled folates |
| 10/16/2008 | CA2683433A1 Nitro-imidazole hypoxia imaging agents |
| 10/09/2008 | WO2008122010A1 Pharmaceutical calcimimetics |
| 10/09/2008 | US20080248485 Radiolabeled 3-[3- (Benzoyl-Amido) Benzyloxy] Aspartic Acid Derivative and Method of Producing the Same |
| 10/08/2008 | EP1978015A1 Precursor compound of radioactive halogen labeled organic compound |