Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678) |
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09/25/2008 | US20080234488 Using Group 8, or compound thereof, as catalyst; deuteration a compound containing aromatic or heterocyclic ring |
09/24/2008 | EP1697279B1 Radical trap in fluoridation of iodinium salt |
09/18/2008 | WO2008110757A1 Separation process |
09/18/2008 | US20080228004 Ligand Protection for Mercaptoacetyl Triglycine |
09/17/2008 | EP1968651A2 Stabilized compositions and methods for radiolabeling pharmaceuticals with alpha-particle emitters |
09/03/2008 | CN100415696C Radical trap in fluoridation of iodonium salt |
08/28/2008 | WO2008101305A1 Method for the elution of 18f fluoride trapped on an anion-exchange phase in a form suitable for efficient radiolabeling without any evaporation step |
08/28/2008 | US20080206820 activated ester of the carboxyl-containing compound (carboxylic acid) is reacted with H217O or H218O in the presence of an activator; labelled amino acid |
08/27/2008 | EP1960324A1 Method for the preparation of [18f]fluoroalkylhalides |
08/27/2008 | CN101253149A Imaging 18F or 11C-labelled alkylthiophenyl guanidines |
08/26/2008 | CA2208981C Novel trienoic retinoid compounds and methods |
08/21/2008 | WO2008101069A1 Synthesis of radioactive materials and compositions of same |
08/21/2008 | WO2008099203A2 Reactions of isotopically enriched elements of phosphorus, sulfur, selenium and tellurium |
08/20/2008 | EP1958928A1 Synthesis of radioactive materials and compositions of same |
08/20/2008 | EP1957116A2 Radiolabelling method using polymers |
08/20/2008 | EP1667947B1 Methods of 11c -radiolabelling phenothiazine and pheno thiazine-like compounds |
08/20/2008 | EP1047455B1 Para-hydrogen labelled agents and their use in non-proton magnetic resonance imaging |
08/06/2008 | EP1951643A1 Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity |
07/30/2008 | EP1603918B1 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof |
07/29/2008 | US7405332 making a fluoro radioactive material [18F]Fluorohaloalkanes radiotracer through halogenation, or solid phase synthesis; use in positron emission tomography (PET) studies |
07/23/2008 | EP1947074A1 Method of rapid methylation of alkene compound and kit for pet tracer preparation using the same |
07/16/2008 | EP1944281A1 18F-labeled compounds, method for the preparation and use thereof |
07/08/2008 | CA2188029C Porphocyanine and cnc-expanded porphyrins |
07/03/2008 | WO2008078589A1 Process for production of precursor compound for radioactive halogen-labeled organic compound |
07/03/2008 | CA2672914A1 Process for production of precursor compound for radioactive halogen-labeled organic compound |
06/26/2008 | WO2008075043A1 Radiolabelling methods |
06/26/2008 | WO2008011033A3 Synthesis of isotopically labeled alpha-keto acids and esters |
06/25/2008 | EP1934160A1 Method for the use of [11c]carbon monoxide in labeling synthesis of 11c-labelled ketones by photo-induced free radical carbonylation |
06/19/2008 | WO2008023251A3 Radiolabeled 1-acetate pet imaging for radiotherapy in head and neck cancer |
06/17/2008 | CA2284732C Analogs of cocaine |
06/12/2008 | US20080138282 Radiolabeled Arylsulfonyl Compounds and Uses Thereof |
06/12/2008 | US20080138281 with C11 or F18 radioisotops; e.g. O-[18F]Fluoromethyl-L-tyrosine or O-[11C]methyl-L-tyrosine; comparison of the radiation dose of each tissue |
06/05/2008 | WO2008066158A1 Method for deuterating alkane |
06/04/2008 | EP1926500A2 Methods of making radiolabeled tracers and precursors thereof |
05/21/2008 | EP1923382A1 [18F] labelled L-glutamic acid, [18F] labelled glutamine, their derivatives, their use and processes for their preparation |
05/14/2008 | EP1919515A2 F-18 peptides for pre targeted positron emission tomography imaging |
05/08/2008 | WO2008052788A1 [f-18]-labeled l-glutamic acid, [f-18]-labeled l-glutamine, derivatives thereof and use thereof and processes for their preparation |
05/08/2008 | WO2007109292A3 Ionizable isotopic labeling reagents for relative quantification by mass spectrometry |
05/08/2008 | CA2667395A1 [f-18]-labeled l-glutamic acid, [f-18]-labeled l-glutamine, their derivatives and their use and processes for their preparation |
05/07/2008 | CN101172162A Methods of [11c]-radiolabelling phenothiazine and phenothiazine-like compounds |
05/06/2008 | US7368474 [18F]-fluorination for use making radiopharmaceuticals for Positron Emission Tomography (PET); reacting a compound of formula 18F-(Linker)-SH with an activated peptide |
04/30/2008 | CN100384792C Method of deuterization |
04/24/2008 | US20080097131 Synthesis of carbon-labeled perfluoroalkyl compounds |
04/15/2008 | US7358229 Deuterated cyclosporin analogs and their use as immunomodulating agents |
04/10/2008 | CA2664700A1 Silicon derivatives for pet imaging |
04/09/2008 | EP1907340A2 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled acids by photo-induced free radical carbonylation under mild conditions using sulfoxides |
04/09/2008 | CN101157649A 18F-Fallypride automatically synthesizing method |
04/03/2008 | DE102006045603A1 New phenyl-carboxyl compounds useful in the preparation of 6-halo-3,4-dihydroxy-L-phenylalanine |
04/01/2008 | US7351870 Synthesis of carbon-labeled perfluoroalkyl compounds |
03/27/2008 | US20080076914 Method of Deprotection |
03/26/2008 | EP1620373B1 Device and method for the fluorination of nucleophiles |
03/26/2008 | CN100376606C Heavy-hydrogenated norbornyl (meth)acrylates, process for producing them, polymers thereof and optical members |
03/13/2008 | WO2008029734A1 Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program |
03/13/2008 | CA2662601A1 Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program |
03/12/2008 | EP1896400A1 Imaging 18f or 11c-labelled alkylthiophenyl guanidines |
03/12/2008 | EP1896380A2 Method for the use of [11c]carbon monoxide in labeling synthesis of 11c-labelled esters and acids by sensitized photo-induced free radical carbonylation |
03/12/2008 | CN100374442C Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof |
03/05/2008 | EP1893246A2 Stereoselective synthesis of amino acid analogs for tumor imaging |
02/28/2008 | WO2008023780A1 Method of rapid methylation, kit for preparing pet tracer and method of producing pet tracer |
02/27/2008 | EP1418950B1 Solid-phase nucleophilic fluorination |
02/27/2008 | CN101133017A Radioactive halogen-labeled phenyloxyaniline derivatives |
02/27/2008 | CN101133005A Methods for the purification of radiolabelled products using a solid-support scavenger |
02/27/2008 | CN101130503A Method for preparing L-serine-**N |
02/27/2008 | CN100371074C Novel catalytic formulation and its preparation method |
02/20/2008 | EP1889823A1 13c,15n,2h labeled proteins for nmr structure determinations and their preparation |
02/19/2008 | CA2220008C Composition and method for tumor imaging |
02/14/2008 | US20080038191 Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production |
02/07/2008 | WO2008015391A1 Method for the purification of radiolabelled compounds |
02/07/2008 | WO2007141506A3 Electrochemically desorbing or adsorbing cryptate [18 f] fluoride complexes |
01/31/2008 | WO2007122488A3 Radiofluorinated compounds and their preparation |
01/30/2008 | EP1882672A1 Method for producing deuterium gas and catalytic deuteration method using deuterium gas obtained thereby |
01/23/2008 | CN101111454A Method for producing deuterium gas and catalytic deuteration method using deuterium gas obtained thereby |
01/16/2008 | EP1077998B1 Labelled glutamine and lysine analogues |
01/09/2008 | EP1874712A2 Preparations of 11c methyl iodide and of the radioligand 11c gb67 |
01/03/2008 | WO2008001098A1 Electrochemical separation of [18f] fluoride from [180] water |
01/03/2008 | DE102006029830A1 Growing of deuterated alanine doped triglycine sulfate monocrystals from a solution for night vision device, comprises arranging a crystal holder in a chamber of a device and pumping the solution in a circulation with the chamber |
12/27/2007 | WO2007147838A1 Radiolabelled ligand for the glycine 1 transporter |
12/27/2007 | WO2007147454A1 Chemical synthesis of cu-64asp (copper-64asparaginase; [64cu]asparaginase) for pet scans and radiotheraphy |
12/27/2007 | US20070297978 for radiolabeling proteins, peptides and ligands with therapeutic radioisotopes such that these radiolabeled agents may be administered directly to patients without the need for additional purification; for the treatment of cancer; e.g. DTPA OR DOTA -antibody or fragments( Fab or Fv fragments) with Y-90 |
12/13/2007 | US20070287837 Solid phase-supported chlorinating agent for the conversion of a radioactive carboxylic acid to a radioactive acid chloride intermediate; forming 11C-labeled esters, amides or amines; negates the need for a separation step; synthesis of radiopharmaceuticals such as (11C)-cyclopentyltheophyline |
12/12/2007 | EP1863749A2 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via ketene using diazo compounds and carbon-isotope monoxide |
12/12/2007 | EP1863748A1 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide |
12/12/2007 | EP1727777B1 Radiosynthesis of acid chlorides |
12/11/2007 | US7307091 Deuterated 3-piperidinopropiophenone and medicaments containing said compounds |
12/11/2007 | CA2442288C A novel catalytic formulation and its preparation |
12/06/2007 | WO2007139923A1 Deuterated aminoglycidyl compounds |
12/06/2007 | WO2007138408A1 11c/18 f-labeled inhibitors of glycogen synthase kinase-3 |
12/06/2007 | US20070280883 Methods for Carbon Isotope Labeling Synthesis of Ketones and Amines by Suzuki Coupling Reactions Using Carbon-Isotope Monoxide |
12/06/2007 | CA2653209A1 Deuterated aminoglycidyl compounds |
12/05/2007 | EP1678198A4 Side chain deuterated amino acids and methods of use |
12/05/2007 | CN101084020A Radiolabelling methods |
12/04/2007 | CA2282563C Method for the preparation of facial metal tricarbonyl compounds and their use in the labelling of biologically active substrates |
11/29/2007 | WO2007135541A1 11c-labeled benzophenone/benzoxazole analogues as an inflammation imaging agent |
11/29/2007 | US20070275442 Side Chain Deuterated Amino Acids Methods Of Use |
11/22/2007 | WO2007132689A1 Process for production of radioactive fluorine-labeled organic compound |
11/22/2007 | WO2007072182A3 Miniaturized liquid surface reactions using nanomolar amounts of concentrated [11c]carbon dioxide in a stationary gas-phase |
11/22/2007 | CA2651786A1 Process for production of radioactive fluorine-labeled organic compound |
11/14/2007 | EP1854781A1 Radioactive halogen-labeled phenyloxyaniline derivatives |
11/08/2007 | WO2007066089A3 Radiolabelling method using polymers |
11/01/2007 | WO2007122488A2 Radiofluorinated compounds and their preparation |