Patents
Patents for C07B 59 - Introduction of isotopes of elements into organic compounds (2,678)
09/2008
09/25/2008US20080234488 Using Group 8, or compound thereof, as catalyst; deuteration a compound containing aromatic or heterocyclic ring
09/24/2008EP1697279B1 Radical trap in fluoridation of iodinium salt
09/18/2008WO2008110757A1 Separation process
09/18/2008US20080228004 Ligand Protection for Mercaptoacetyl Triglycine
09/17/2008EP1968651A2 Stabilized compositions and methods for radiolabeling pharmaceuticals with alpha-particle emitters
09/03/2008CN100415696C Radical trap in fluoridation of iodonium salt
08/2008
08/28/2008WO2008101305A1 Method for the elution of 18f fluoride trapped on an anion-exchange phase in a form suitable for efficient radiolabeling without any evaporation step
08/28/2008US20080206820 activated ester of the carboxyl-containing compound (carboxylic acid) is reacted with H217O or H218O in the presence of an activator; labelled amino acid
08/27/2008EP1960324A1 Method for the preparation of [18f]fluoroalkylhalides
08/27/2008CN101253149A Imaging 18F or 11C-labelled alkylthiophenyl guanidines
08/26/2008CA2208981C Novel trienoic retinoid compounds and methods
08/21/2008WO2008101069A1 Synthesis of radioactive materials and compositions of same
08/21/2008WO2008099203A2 Reactions of isotopically enriched elements of phosphorus, sulfur, selenium and tellurium
08/20/2008EP1958928A1 Synthesis of radioactive materials and compositions of same
08/20/2008EP1957116A2 Radiolabelling method using polymers
08/20/2008EP1667947B1 Methods of 11c -radiolabelling phenothiazine and pheno thiazine-like compounds
08/20/2008EP1047455B1 Para-hydrogen labelled agents and their use in non-proton magnetic resonance imaging
08/06/2008EP1951643A1 Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity
07/2008
07/30/2008EP1603918B1 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof
07/29/2008US7405332 making a fluoro radioactive material [18F]Fluorohaloalkanes radiotracer through halogenation, or solid phase synthesis; use in positron emission tomography (PET) studies
07/23/2008EP1947074A1 Method of rapid methylation of alkene compound and kit for pet tracer preparation using the same
07/16/2008EP1944281A1 18F-labeled compounds, method for the preparation and use thereof
07/08/2008CA2188029C Porphocyanine and cnc-expanded porphyrins
07/03/2008WO2008078589A1 Process for production of precursor compound for radioactive halogen-labeled organic compound
07/03/2008CA2672914A1 Process for production of precursor compound for radioactive halogen-labeled organic compound
06/2008
06/26/2008WO2008075043A1 Radiolabelling methods
06/26/2008WO2008011033A3 Synthesis of isotopically labeled alpha-keto acids and esters
06/25/2008EP1934160A1 Method for the use of [11c]carbon monoxide in labeling synthesis of 11c-labelled ketones by photo-induced free radical carbonylation
06/19/2008WO2008023251A3 Radiolabeled 1-acetate pet imaging for radiotherapy in head and neck cancer
06/17/2008CA2284732C Analogs of cocaine
06/12/2008US20080138282 Radiolabeled Arylsulfonyl Compounds and Uses Thereof
06/12/2008US20080138281 with C11 or F18 radioisotops; e.g. O-[18F]Fluoromethyl-L-tyrosine or O-[11C]methyl-L-tyrosine; comparison of the radiation dose of each tissue
06/05/2008WO2008066158A1 Method for deuterating alkane
06/04/2008EP1926500A2 Methods of making radiolabeled tracers and precursors thereof
05/2008
05/21/2008EP1923382A1 [18F] labelled L-glutamic acid, [18F] labelled glutamine, their derivatives, their use and processes for their preparation
05/14/2008EP1919515A2 F-18 peptides for pre targeted positron emission tomography imaging
05/08/2008WO2008052788A1 [f-18]-labeled l-glutamic acid, [f-18]-labeled l-glutamine, derivatives thereof and use thereof and processes for their preparation
05/08/2008WO2007109292A3 Ionizable isotopic labeling reagents for relative quantification by mass spectrometry
05/08/2008CA2667395A1 [f-18]-labeled l-glutamic acid, [f-18]-labeled l-glutamine, their derivatives and their use and processes for their preparation
05/07/2008CN101172162A Methods of [11c]-radiolabelling phenothiazine and phenothiazine-like compounds
05/06/2008US7368474 [18F]-fluorination for use making radiopharmaceuticals for Positron Emission Tomography (PET); reacting a compound of formula 18F-(Linker)-SH with an activated peptide
04/2008
04/30/2008CN100384792C Method of deuterization
04/24/2008US20080097131 Synthesis of carbon-labeled perfluoroalkyl compounds
04/15/2008US7358229 Deuterated cyclosporin analogs and their use as immunomodulating agents
04/10/2008CA2664700A1 Silicon derivatives for pet imaging
04/09/2008EP1907340A2 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled acids by photo-induced free radical carbonylation under mild conditions using sulfoxides
04/09/2008CN101157649A 18F-Fallypride automatically synthesizing method
04/03/2008DE102006045603A1 New phenyl-carboxyl compounds useful in the preparation of 6-halo-3,4-dihydroxy-L-phenylalanine
04/01/2008US7351870 Synthesis of carbon-labeled perfluoroalkyl compounds
03/2008
03/27/2008US20080076914 Method of Deprotection
03/26/2008EP1620373B1 Device and method for the fluorination of nucleophiles
03/26/2008CN100376606C Heavy-hydrogenated norbornyl (meth)acrylates, process for producing them, polymers thereof and optical members
03/13/2008WO2008029734A1 Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program
03/13/2008CA2662601A1 Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program
03/12/2008EP1896400A1 Imaging 18f or 11c-labelled alkylthiophenyl guanidines
03/12/2008EP1896380A2 Method for the use of [11c]carbon monoxide in labeling synthesis of 11c-labelled esters and acids by sensitized photo-induced free radical carbonylation
03/12/2008CN100374442C Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof
03/05/2008EP1893246A2 Stereoselective synthesis of amino acid analogs for tumor imaging
02/2008
02/28/2008WO2008023780A1 Method of rapid methylation, kit for preparing pet tracer and method of producing pet tracer
02/27/2008EP1418950B1 Solid-phase nucleophilic fluorination
02/27/2008CN101133017A Radioactive halogen-labeled phenyloxyaniline derivatives
02/27/2008CN101133005A Methods for the purification of radiolabelled products using a solid-support scavenger
02/27/2008CN101130503A Method for preparing L-serine-**N
02/27/2008CN100371074C Novel catalytic formulation and its preparation method
02/20/2008EP1889823A1 13c,15n,2h labeled proteins for nmr structure determinations and their preparation
02/19/2008CA2220008C Composition and method for tumor imaging
02/14/2008US20080038191 Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production
02/07/2008WO2008015391A1 Method for the purification of radiolabelled compounds
02/07/2008WO2007141506A3 Electrochemically desorbing or adsorbing cryptate [18 f] fluoride complexes
01/2008
01/31/2008WO2007122488A3 Radiofluorinated compounds and their preparation
01/30/2008EP1882672A1 Method for producing deuterium gas and catalytic deuteration method using deuterium gas obtained thereby
01/23/2008CN101111454A Method for producing deuterium gas and catalytic deuteration method using deuterium gas obtained thereby
01/16/2008EP1077998B1 Labelled glutamine and lysine analogues
01/09/2008EP1874712A2 Preparations of 11c methyl iodide and of the radioligand 11c gb67
01/03/2008WO2008001098A1 Electrochemical separation of [18f] fluoride from [180] water
01/03/2008DE102006029830A1 Growing of deuterated alanine doped triglycine sulfate monocrystals from a solution for night vision device, comprises arranging a crystal holder in a chamber of a device and pumping the solution in a circulation with the chamber
12/2007
12/27/2007WO2007147838A1 Radiolabelled ligand for the glycine 1 transporter
12/27/2007WO2007147454A1 Chemical synthesis of cu-64asp (copper-64asparaginase; [64cu]asparaginase) for pet scans and radiotheraphy
12/27/2007US20070297978 for radiolabeling proteins, peptides and ligands with therapeutic radioisotopes such that these radiolabeled agents may be administered directly to patients without the need for additional purification; for the treatment of cancer; e.g. DTPA OR DOTA -antibody or fragments( Fab or Fv fragments) with Y-90
12/13/2007US20070287837 Solid phase-supported chlorinating agent for the conversion of a radioactive carboxylic acid to a radioactive acid chloride intermediate; forming 11C-labeled esters, amides or amines; negates the need for a separation step; synthesis of radiopharmaceuticals such as (11C)-cyclopentyltheophyline
12/12/2007EP1863749A2 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via ketene using diazo compounds and carbon-isotope monoxide
12/12/2007EP1863748A1 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide
12/12/2007EP1727777B1 Radiosynthesis of acid chlorides
12/11/2007US7307091 Deuterated 3-piperidinopropiophenone and medicaments containing said compounds
12/11/2007CA2442288C A novel catalytic formulation and its preparation
12/06/2007WO2007139923A1 Deuterated aminoglycidyl compounds
12/06/2007WO2007138408A1 11c/18 f-labeled inhibitors of glycogen synthase kinase-3
12/06/2007US20070280883 Methods for Carbon Isotope Labeling Synthesis of Ketones and Amines by Suzuki Coupling Reactions Using Carbon-Isotope Monoxide
12/06/2007CA2653209A1 Deuterated aminoglycidyl compounds
12/05/2007EP1678198A4 Side chain deuterated amino acids and methods of use
12/05/2007CN101084020A Radiolabelling methods
12/04/2007CA2282563C Method for the preparation of facial metal tricarbonyl compounds and their use in the labelling of biologically active substrates
11/2007
11/29/2007WO2007135541A1 11c-labeled benzophenone/benzoxazole analogues as an inflammation imaging agent
11/29/2007US20070275442 Side Chain Deuterated Amino Acids Methods Of Use
11/22/2007WO2007132689A1 Process for production of radioactive fluorine-labeled organic compound
11/22/2007WO2007072182A3 Miniaturized liquid surface reactions using nanomolar amounts of concentrated [11c]carbon dioxide in a stationary gas-phase
11/22/2007CA2651786A1 Process for production of radioactive fluorine-labeled organic compound
11/14/2007EP1854781A1 Radioactive halogen-labeled phenyloxyaniline derivatives
11/08/2007WO2007066089A3 Radiolabelling method using polymers
11/01/2007WO2007122488A2 Radiofluorinated compounds and their preparation
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