Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
10/1999
10/14/1999WO1999036544A3 Neisseria meningitidis antigens
10/14/1999WO1999036094A9 Composition and method for treating metastatic tumors or cancer induced by cells expressing sv40 tumor antigen
10/14/1999WO1999036090A9 Oral delivery of nucleic acid vaccines by particulate complexes
10/14/1999WO1999033999A9 Mitogen-activated protein kinase kinase 7 (mkk7)
10/14/1999WO1999022773A3 Sequences for targeting metastatic cells
10/14/1999WO1999021589A3 Use of vectors such as adenoviruses and/or adeno associated viruses and/or retroviruses and/or herpes simplex viruses and/or liposomes and/or plasmids as a vehicle for genetic information enabling mammal cells to produce agents for the treatment of bone pathologies
10/14/1999WO1999010486A3 Mdm2-specific antisense oligonucleotides
10/14/1999DE19816141A1 New polyspecific binding agents containing variable heavy and light constructs connected via peptide linker, used for treatment, prevention or diagnosis of e.g. cancer
10/14/1999DE19807426A1 Verfahren zur Behandlung von Erkrankungen oder Störungen des Innenohrs A method for the treatment of diseases or disorders of the inner ear
10/14/1999CA2328181A1 Immunomodulatory compositions of mmtv antigens and methods of using same
10/14/1999CA2327737A1 Polyene macrolide derivatives, use for vectoring molecules
10/14/1999CA2327367A1 New compounds for dna-transfection
10/14/1999CA2326739A1 Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient
10/14/1999CA2326598A1 Fusion proteins of mycobacterium tuberculosis antigens and their uses
10/14/1999CA2326388A1 A polypeptide comprising the amino acid of an n-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
10/14/1999CA2326130A1 Cationic lipid formulation delivering nucleic acid to peritoneal tumors
10/14/1999CA2325849A1 Pentaerythritol lipid derivatives
10/14/1999CA2324931A1 Novel nucleic acid transfer agents, compositions containing same and uses
10/14/1999CA2324656A1 Protein variant of the net1 locus
10/13/1999EP0949332A2 HSSCRG1 polypeptides
10/13/1999EP0949331A1 Established microglia
10/13/1999EP0948646A1 Methods for identifying genes essential to the growth of an organism
10/13/1999EP0948638A1 Method for preparing compositions for transferring nucleic acids
10/13/1999EP0948636A1 Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid, a non-viral and non-plasmid transfecting agent
10/13/1999EP0948635A2 Human and mammalian dna replication origin consensus sequences
10/13/1999EP0948622A1 Human mage-like protein
10/13/1999EP0948621A1 Junctional adhesion molecule (jam), a transmembrane protein of tight junctions
10/13/1999EP0948619A1 Expression of proteins for treating asthma via ligand mediated activation of their encoding genes
10/13/1999EP0948618A1 HUMAN POLYHOMEOTIC 2($i(hph2)) ACTS AS AN ONCOGENE
10/13/1999EP0948614A2 Novel expression vectors containing accessory molecule ligand genes and their use for immunomodulation and treatment of malignancies and autoimmune disease
10/13/1999EP0948611A1 Ve-cadherin promoter and its uses
10/13/1999EP0948609A2 Llg polypeptides of the triacylglycerol lipase family, and compositions and methods for their use in enzymatic hydrolysis, and protein and gene therapies
10/13/1999EP0948594A1 Method and device for microinjection of macromolecules into non-adherent cells
10/13/1999EP0948534A1 Meningococcus vaccine comprising the valence of bz83 strain
10/13/1999EP0948522A1 Therapeutic and diagnostic agents capable of modulating cellular responsiveness to cytokines
10/13/1999EP0948520A1 Tissue specific expression of retinoblastoma protein
10/13/1999EP0948515A1 Human b-cell translocation genes-2 and 3
10/13/1999EP0948513A1 Delivery construct for antisense nucleic acids and methods of use
10/13/1999EP0948510A1 Immunostimulatory nucleic acid molecules
10/13/1999EP0948508A1 Novel coding sequences from herpes simplex virus type-2
10/13/1999EP0948360A1 Novel lipid compounds and compositions containing same used for the transfer of at least an active substance, in particular a polynucleotide, in a target cell and therapeutic use
10/13/1999EP0948348A1 Manipulation of non-terminally differentiated cells using the notch pathway
10/13/1999EP0850300B1 Method of modulating gene expression with reduced immunostimulatory response
10/13/1999CN1231601A Oral delayed immediate release formulation and method of preparation therefor
10/12/1999US5965722 Oligonucleotide with methylene(methylimino) linkages alternating with phosphorothioate or phosphodiester linkages; with increased nuclease resistance, stability, affinity for messenger rna; anticarcinogenic/antiarrhythmia agents
10/12/1999US5965720 With sequence complementary to messenger rna from a gene selected from the group consisting of c-myc, c-myb, c-fos, c-kit, ras and bcr/abl; antisense/anticarcinogenic agents
10/12/1999US5965703 Bcl-x/bcl-2 associated death polypeptide; used for regulating apoptosis in treating acquired immune deficiency syndrome and neurodegenerative diseases; antiischemic agents
10/12/1999US5965542 Use of temperature to control the size of cationic liposome/plasmid DNA complexes
10/12/1999US5965541 Chimeric adenovirus coat protein of non-native amino acid sequence, which directs entry into cells of a vector more efficiently than a vector which is identical but with a wild-type adenovirus coat protein; ex vivo gene therapy
10/12/1999US5965439 Host defense enhancement
10/12/1999US5965435 Genetically engineered genes containing the herpes virus of turkeys gc gene, thymidine kinase region of marek's disease virus, infectious laryngotracheitis virus's open reading frame and ribonucleotide reductase genes; for vaccines
10/12/1999US5965427 Human RAD50 gene and methods of use thereof
10/12/1999US5965420 A protein which stimulates cell proliferation; treatment of bone loss due to osteoporosis; treat adult respiratory disease syndrome, parkinson'disease, huntington's disease; antiarthritic/anticarcinogenic agents; antiallergens
10/12/1999US5965419 Purified sulfotransferase
10/12/1999US5965416 Arginyl tRNA synthetase from staphyloccus aureus
10/12/1999US5965404 Adding nucleic acid/polycation complexes to animal cells in presence of ethylene glycol and/or glycerol; for simple and accurate transfection of cells for gene therapy and tumor vaccine production
10/12/1999US5965398 A cell growth inhibitor gene; diagnosis and treatment of breast cancer; anticarcinogenic agents
10/12/1999US5965397 Protein factor, cytokines, lymphokines, interferons, and interleukins, and colony stimulating factors; treatment of osteoporosis, stimulating or bone growth, regeneration of nerve and brain tissue, alzheimer/huntington disease's
10/12/1999US5965392 A nucleic acid molecule; treating obesity or anorexia
10/12/1999US5965388 Isolated polynucleotides; diagnosis and treatment autoimmune diseases, tissue rejection, allergies, acquired immune deficiency disease; viricides, bactericides and fungicides; anticarcinogenic agents
10/12/1999US5965381 A mutant strain deficient in producing functional effector proteins; used for heterologous protein transfer into antigen presenting cells; treating infections by pathogens; inducing cellular immune response
10/12/1999US5965367 Purified bradykinin B1 receptor
10/12/1999US5965360 Diagnosis of metastatic cancer by the mts-1 gene
10/12/1999US5965157 Method to provide for production of hair coloring pigments in hair follicles
10/12/1999US5965138 Recombinant chimeric virus and vaccine comprising a long viral genomic region from the herpes virus of turkeys and a short viral genomic region from marek's disease virus; immunizing birds
10/12/1999US5965126 use of mutant alkyltransferases for gene therapy to protect from toxicity of therapeutic alkylating agents
10/12/1999US5965125 Hybrid matrix implants and explants
10/08/1999CA2234349A1 Method of reducing boar taint
10/07/1999WO1999050461A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
10/07/1999WO1999050457A1 Directed antisense libraries
10/07/1999WO1999050456A1 P53-regulated genes
10/07/1999WO1999050432A1 Inducible alphaviral gene expression system
10/07/1999WO1999050431A1 Novel retroviral constructs
10/07/1999WO1999050425A2 Regulated apoptosis using chemically induced dimerization of apoptosis factors
10/07/1999WO1999050421A1 Ubiquitin conjugating enzyme
10/07/1999WO1999050418A1 Treatment and diagnosis of staphylococcal infections
10/07/1999WO1999050414A1 Blk genes, gene products and uses thereof in apoptosis
10/07/1999WO1999050412A1 HUMAN p51 GENES AND GENE PRODUCTS THEREOF
10/07/1999WO1999050411A2 Tumour-specific expression control region and the use thereof
10/07/1999WO1999050410A1 Novel molecules expressed during muscle development and genetic sequences encoding the same
10/07/1999WO1999050403A2 Method and reagents for the treatment of diseases or conditions related to molecules involved in angiogenic responses
10/07/1999WO1999050296A1 Treatment and prevention of vascular disease
10/07/1999WO1999050285A2 Production methods and uses of a retrovirus
10/07/1999WO1999050284A2 Nucleic acid molecules which code proteins influencing bone development
10/07/1999WO1999050279A1 Antisense compositions for detecting and inhibiting telomerase reverse transcriptase
10/07/1999WO1999049909A2 Revascularization apparatus having coaxial channeling and injecting means
10/07/1999WO1999049898A1 Progression elevated gene-3 and uses thereof
10/07/1999WO1999049774A2 Methods for the diagnosis and treatment of lung cancer
10/07/1999WO1999049734A1 Method of inhibiting immune system destruction of transplanted viable cells
10/07/1999WO1999040197A3 Variants of the angiogenic factor vascular endothelial cell growth factor: vegf
10/07/1999WO1999040109A3 Recombinant mistletoe lectines
10/07/1999WO1999036102A9 GENETIC MANIPULATION BY 3' UNTRANSLATED SEQUENCES OF mRNA
10/07/1999WO1999031251A9 Method and means for producing high titer, safe, recombinant lentivirus vectors
10/07/1999WO1999021996A9 Methods and compositions for the diagnosis and treatment of cataracts
10/07/1999DE19816395A1 Menschliche Nukleinsäuresequenzen aus Ovar-Normalgewebe Nucleic acid sequences from human ovarian normal tissue
10/07/1999DE19814963A1 MAPKAP Kinase 2-Hemmer und ihre Verwendung für die anti-inflammatorische Therapie MAPKAP kinase 2 inhibitors and their use for the anti-inflammatory therapy
10/07/1999DE19814861A1 Neue Proteinvariante des NET1-Locus New protein variant of NET1 locus
10/07/1999CA2735260A1 Methods for the diagnosis and treatment of lung cancer by detection of proto-oncogene overexpression
10/07/1999CA2731416A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
10/07/1999CA2325564A1 Inducible alphaviral gene expression system
1 ... 742 743 744 745 746 747 748 749 750 751 752 753 754 755 756 757 758 759 760 761 762 ... 870