Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
07/1990
07/11/1990EP0376968A1 Chromosome-specific nucleic acid probe for familial polyposis coli.
06/1990
06/28/1990WO1990006997A1 Genetically engineered endothelial cells and use thereof
06/28/1990WO1990006936A1 Sequential peptide and oligonucleotide synthesis using immunoaffinity techniques
06/28/1990WO1990006934A1 Triple stranded nucleic acid and methods of use
06/28/1990WO1990006757A1 Grafting genetically modified cells to treat diseases of the central nervous system
06/27/1990EP0375408A1 Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
06/23/1990CA2006657A1 Repression of receptor transcriptional activity
06/21/1990CA2006334A1 Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques
06/13/1990CA2005199A1 Genetically engineered endothelial cells and use thereof
05/1990
05/31/1990WO1990002803A3 Viral vaccines
05/17/1990WO1990005180A1 Products and methods for controlling the suppression of the neoplastic phenotype
05/17/1990WO1990002802A3 Viral nucleotide sequences
04/1990
04/10/1990US4916071 Poly-kringle plasminogen activator
03/1990
03/22/1990WO1990002803A2 Viral vaccines
03/22/1990WO1990002802A2 Viral nucleotide sequences
03/22/1990WO1990002551A2 Prophylaxis and treatment of nervous system diseases with melanin
02/1990
02/27/1990US4904582 Novel amphiphilic nucleic acid conjugates
02/22/1990WO1990001545A1 Method and materials relating to impdh and gmp production
12/1989
12/27/1989CN1038306A Recombinant retroviruses
12/14/1989WO1989012110A1 Labeled nucleic acid probe
12/14/1989WO1989012109A1 Gene therapy using gene fusions for genetic or acquired disorders
11/1989
11/29/1989EP0343217A1 Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
11/08/1989EP0340793A2 Endowing cells with antibody specificity
10/1989
10/05/1989WO1989009271A1 Recombinant retroviruses
09/1989
09/27/1989EP0334301A1 Recombinant retroviruses
09/20/1989EP0332667A1 Vector for integration site independent gene expression in mammalian host cells
09/13/1989EP0331939A2 Method and compositions for conferring resistance to retroviral infection
09/12/1989US4866042 Method for the delivery of genetic material across the blood brain barrier
09/08/1989WO1989008146A1 Inhibition of htlv-iii by exogenous oligonucleotides
09/08/1989WO1989007944A1 Device for site directed neovascularization and method for same
08/1989
08/24/1989WO1989007136A3 Modified hepatocytes and uses therefor
08/10/1989WO1989007136A2 Modified hepatocytes and uses therefor
08/10/1989WO1989006286A3 Probes for and methods of diagnosis for muscular dystrophy
07/1989
07/26/1989EP0325191A2 Composition and method for protecting against diseases caused by microorganisms
07/13/1989WO1989006286A2 Probes for and methods of diagnosis for muscular dystrophy
06/1989
06/28/1989EP0321548A1 Novel amphiphilic nucleic acid conjugates
06/15/1989WO1989005358A1 Dna and rna molecules stabilized by modifications of the 3'-terminal phosphodiester linkage and their use as nucleic acid probes and as therapeutic agents to block the expression of specifically targeted genes
06/15/1989WO1989005349A1 Method of combating viral infections
06/15/1989WO1989005345A1 Genetic modification of endothelial cells
06/01/1989WO1989004663A1 Method for the delivery of genetic material across the blood brain barrier
05/1989
05/18/1989WO1989004168A1 Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
05/05/1989WO1989003849A1 Oligonucleotide-polyamide conjugates
04/1989
04/20/1989WO1989003429A1 Recombinant avipox virus
03/1989
03/23/1989WO1989002468A1 Transduced fibroblasts and uses therefor
02/1989
02/23/1989WO1989001517A1 Vector for integration site independent gene expression in mammalian host cells
02/23/1989WO1989001481A1 Chromosome-specific nucleic acid probe for familial polyposis coli
12/1988
12/29/1988WO1988010311A1 Recombinant human cytomegalovirus containing foreign gene and use thereof
12/15/1988WO1988009810A1 Novel amphiphilic nucleic acid conjugates
12/14/1988EP0294595A2 Polynucleotide composition and method for its production
12/01/1988WO1988009383A1 Gene transfer for drug resistance
11/1988
11/30/1988EP0293193A2 Gene transfer for drug resistance
11/03/1988WO1988008450A1 Gene therapy for metabolite disorders
11/03/1988WO1988008306A1 Transkaryotic implantation
11/02/1988EP0289034A2 Transkaryotic implantation
08/1988
08/24/1988EP0279582A2 DNA sequences to target proteins to the mammary gland for efficient secretion
03/1988
03/09/1988EP0259031A2 Human DNA in the diagnosis of retinoblastoma
10/1987
10/28/1987EP0243204A2 Infective drug delivery system
08/1987
08/12/1987EP0231495A2 One-step method and polynucleotide compounds for hybridizing to target polynucleotides
08/11/1987US4686098 Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
04/1987
04/01/1987EP0215907A1 Parasite-derived resistance
03/1987
03/11/1987EP0213794A1 Poly-kringle plasminogen activator
09/1986
09/25/1986WO1986005516A1 Parasite-derived resistance
01/1986
01/29/1986EP0169787A1 Use of oligonucleotides bonded to an intercalating agent as drugs
11/1985
11/21/1985EP0161640A2 Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo