Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
11/1999
11/02/1999US5976793 Methods of transcriptionally modulating gene expression and of discovering chemicals capable as gene expression modulators
11/02/1999US5976567 Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
11/02/1999US5976535 Pretargeting protocols for the enhanced localization of cytotoxins to target sites and cytotoxic combinations useful therefore
11/02/1999CA2119443C Human cyclin e
10/1999
10/28/1999WO1999054706A2 Method of treating interstitial cystitis with recombinant hb-egf
10/28/1999WO1999054507A1 Repeat polymorphism in the frataxin gene and uses therefor
10/28/1999WO1999054493A2 Novel mutations in the freac3 gene for diagnosis and prognosis of glaucoma and anterior segment dysgenesis
10/28/1999WO1999054491A1 Use of murine myosin heavy chain promoters for gene therapy and production of transgenics
10/28/1999WO1999054485A1 A method for inhibiting tumor invasion or spreading in a subject
10/28/1999WO1999054482A1 Dna fragmentation factor involved in apoptosis
10/28/1999WO1999054481A1 Mutant having uracil phosphoribosyl transferase activity
10/28/1999WO1999054465A2 Gene encoding syntaxin interacting protein
10/28/1999WO1999054464A1 MUTATED PEPTIDE COMPOUNDS, DERIVED FROM hsp70, USEFUL IN CANCER IMMUNOTHERAPY
10/28/1999WO1999054463A2 Human k+ ion channel and therapeutic applications thereof
10/28/1999WO1999054461A2 Human nucleic acid sequences of endometrium tumour tissue
10/28/1999WO1999054460A2 Human nucleic acid sequences of normal bladder tissue
10/28/1999WO1999054459A2 Nucleic acid molecules with novel chemical compositions capable of modulating gene expression
10/28/1999WO1999054456A1 ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF INTEGRIN αv-SUBUNIT EXPRESSION
10/28/1999WO1999054452A1 Methods and substances for preventing and treating autoimmune disease
10/28/1999WO1999054451A1 Neuroendocrine cells secreting insulin ans uses thereof
10/28/1999WO1999054449A2 Dyskerine and dyskerine coding dna molecule, vectors containing the same, antibodies against dyskerin and utilization of said elements
10/28/1999WO1999054447A2 Human nucleic acid sequences of bladder tumour tissue
10/28/1999WO1999054445A2 Combination therapy using nucleic acids and conventional drugs
10/28/1999WO1999054444A2 Combination therapy using nucleic acids and radio therapy
10/28/1999WO1999054440A1 CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF
10/28/1999WO1999054353A2 Human nucleic acid sequences of normal uterus tissue
10/28/1999WO1999054349A2 Dermatophagoides nucleic acid molecules, proteins and uses thereof
10/28/1999WO1999054341A1 Enhanced antisense modulation of icam-1
10/28/1999WO1999053961A1 Peptides for efficient gene transfer
10/28/1999WO1999053960A2 Enhancing immune responses to genetic immunization by using a chemokine
10/28/1999WO1999053959A2 Use of viral vectors for treatment of the injured peripheral and central nervous system
10/28/1999WO1999053943A2 Therapeutic angiogenic factors and methods for their use
10/28/1999WO1999053942A1 Compositions comprising osteoprotegerin for the prevention and treatment of cardiovascular diseases
10/28/1999WO1999043812A3 Dlc-1 gene, a putative tumors suppressor gene
10/28/1999WO1999042580A8 Gaba receptors and their uses
10/28/1999WO1999041404A3 Novel means and methods for the preparation and activation of nucleoside and nucleotide based drugs
10/28/1999WO1999040946A3 Methods and compositions for modulating leptin activity
10/28/1999WO1999040180A3 Expanded and genetically modified populations of human hematopoietic stem cells
10/28/1999WO1999039740A3 Sensitizing cells to compounds using lipid-mediated gene and compound delivery
10/28/1999WO1999035255A3 Compositions and methods for regulated secretion from neuroendocrine cell lines
10/28/1999WO1999035245A3 Methods for preparing and using immortalized human neuroendocrine cells
10/28/1999WO1999035243A9 Extension of cellular lifespan, methods and reagents
10/28/1999WO1999032516A3 Pharmaceutical compositions containing the long pentraxin ptx3
10/28/1999WO1999029341A3 Methods for enhancement of protective immume responses employing leishmania polypeptides
10/28/1999WO1999005272A9 Use of transcription factor brn-3a
10/28/1999DE19818620A1 New polypeptides and their nucleic acids, useful for treatment of bladder tumor and identification of therapeutic agents
10/28/1999DE19818619A1 New nucleic acid sequences expressed in bladder tumor tissue, and derived polypeptides, for treatment of bladder tumor and identification of therapeutic agents
10/28/1999DE19817118C1 New nucleic acid encoding human dyskerin, for diagnosis, treatment and prevention of dyskeratosis congenita and for stabilizing chromosomes
10/28/1999CA2329010A1 Therapeutic angiogenic factors and methods for their use
10/28/1999CA2328774A1 Method of treating interstitial cystitis with recombinant heparin-binding epidermal growth factor-like growth factor (hb-egf)
10/28/1999CA2326823A1 Nucleic acid molecules with novel chemical compositions capable of modulating gene expression
10/28/1999CA2326685A1 Enhancing immune responses to genetic immunization by using a chemokine
10/28/1999CA2326623A1 Gene encoding syntaxin interacting protein
10/28/1999CA2325864A1 Mutated peptide compounds, derived from hsp70, useful in cancer immunotherapy
10/28/1999CA2325821A1 Antisense oligonucleotides for the inhibition of integrin .alpha.v-subunit expression
10/28/1999CA2325663A1 Novel mutations in the freac3 gene for diagnosis and prognosis of glaucoma and anterior segment dysgenesis
10/28/1999CA2325596A1 Combination therapy using nucleic acids and radio therapy
10/28/1999CA2325573A1 A method for inhibiting tumor invasion or spreading in a subject
10/28/1999CA2325561A1 Combination therapy using nucleic acids and conventional drugs
10/28/1999CA2325391A1 Dermatophagoides nucleic acid molecules, proteins and uses thereof
10/28/1999CA2323571A1 Novel human k+ ion channel and therapeutic applications thereof
10/27/1999EP0952218A2 Single chain, multiple antigen-binding molecule, its preparation and use
10/27/1999EP0952214A1 Aviadenovirus
10/27/1999EP0951568A1 Methods for detecting and inhibiting the rna component of telomerase
10/27/1999EP0951559A1 Recombinant pox virus for immunization against tumor-associated antigens
10/27/1999EP0951556A2 Disease associated protein tyrosine phosphatases
10/27/1999EP0951553A2 Adenovirus e4 proteins for inducing cell death
10/27/1999EP0951545A2 Human gtp-binding proteins
10/27/1999EP0951544A2 Methods for administration of recombinant gene delivery vehicles for treatment of human disease
10/27/1999EP0951543A1 Human glycine transporter
10/27/1999EP0951542A2 Secreted proteins and polynucleotides encoding them
10/27/1999EP0951541A1 Biomarkers and targets for diagnosis, prognosis and management of prostate disease
10/27/1999EP0951540A2 Antisense nucleic acids and hammerhead ribozymes
10/27/1999EP0951536A1 Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them
10/27/1999EP0951481A1 Use of substances with immunomodulating activity for the treatment of amyotrophic lateral sclerosis
10/27/1999EP0951469A1 Novel compounds
10/27/1999EP0951296A1 NOVEL FtsL
10/27/1999EP0759938A4 Neurogenic differentiation (neurod) genes and proteins
10/27/1999EP0590082B1 Antisense oligonucleotide inhibition of the ras gene
10/27/1999CN1233291A Method for recombinant adeno-associated virus-directed gene therapy
10/27/1999CN1233289A TNF-Beta-like protein for treating prostate cancer, and related nucleic acid molecules, pharmaceutical compositions and methods
10/27/1999CN1233187A HIVp-17 peptide fragment, compositions containing and methods for producing and using same
10/26/1999US5973136 Inverted chimeric oligonucleotides
10/26/1999US5973119 Cyclin E genes and proteins
10/26/1999US5972902 DNA encoding human IL-6 receptor antagonist and protein encoded thereby
10/26/1999US5972901 Making a composition for delivering an oligonucleotide to a mammalian cell by providing a peptide target binding moiety being capable of binding to a serpin enzyme complex receptor, polylysine, an oligonucleotide vector; conjugating, coupling
10/26/1999US5972900 Conjugating target binding moiety consisting of an antibody or fragment which binds to secretory component of polymeric immunoglobulin receptor on surface of epithelium cell, nucleic acid binder, expression vector, compacting, administering
10/26/1999US5972899 Apoptosis induced by Shigella IpaB
10/26/1999US5972896 Antiangiogenic peptides and methods for inhibiting angiogenesis
10/26/1999US5972707 Gene delivery system
10/26/1999US5972706 Recombinant cytopathic viruses which are capable of replication and/or expression of late region genes in neoplastic mammalian cells but are essentially non-replicable in non-neoplastic cells, methods for constructing and
10/26/1999US5972676 Diagnosis and treatment of AUR-1 and/or AUR-2 related disorders
10/26/1999US5972674 May be used, for example, to identify antibodies and other agents that inhibit or activate signal transduction via the nf-.kappa.b cascade.
10/26/1999US5972666 Assembly-deficient herpesvirus vaccine
10/26/1999US5972651 Polynucleotides and polypeptides of the fifty-four homologue family, (ffh); vectors and transformed host cells; ffh are components of protein secretory apparatus and their inhibition of function is deleterious to bacteria cells
10/26/1999US5972650 Can be used as vehicles for the delivery of nucleic acids that can serve as therapeutic agents and as part of vaccines designed to immunize people or animals against viral diseases.
10/26/1999US5972606 A polypeptide; treating osteoporosis, eating disorders, brain disorders, adult respiratory disease syndrome, huntington'sdisease, ulcers, cardiovascular disorders, parkinson's disease;
10/26/1999US5972600 Separation of active complexes
10/26/1999US5972337 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
10/21/1999WO1999053085A2 Selective regulation of adenovirus production
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