Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
11/1999
11/24/1999EP0797663A4 Sox-9 gene and protein and use in the regeneration of bone or cartilage
11/24/1999CN1236390A Angiogenic factor and use thereof of treating cardiovascular disease
11/23/1999US5990388 Transgenic plant expressing a cloned dna encoding a vaccinia virus e3l protein at a level to complex and sequester double-stranded rna-like structure of virus/viroid; biological pest control; viricides
11/23/1999US5990299 Control of CD44 gene expression for therapeutic use
11/23/1999US5990279 Transport protein for gene therapy using adeno-associated virus vector
11/23/1999US5990092 GATA-6 transcription factor: compositions and methods
11/23/1999US5990091 First nucleic acid molecule to be expressed, and a second nucleic acid molecule encoding a transcription factor and translation factor, where there is co-temporal expression so expression of the second enhances expression of the first
11/23/1999US5990089 Introducing a polynucleotide into a eukaryotic cell in a living animal comprising contacting the cell with a composition comprising a polynucleotide and a dendrimer polycation coupled to the polynucleotide
11/23/1999US5990088 Method for treating kaposi's sarcoma with antisense oligonucleotides
11/23/1999US5989884 Polypeptides of the histidyl transfer rna synthetase family; for screening of antibiotics, bactericides, and bacteristats for treatment and prevention of clamydial infections; diagnosis
11/23/1999US5989864 DNA encoding spo-rel polypeptides
11/23/1999US5989858 Dead-type ATP-dependent RNA helicase (DbpB) from Staphylococcus aureus
11/23/1999US5989834 Contacting nonneuronal cells transfected with vector; gene expression
11/23/1999US5989803 Method for treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase
11/23/1999US5989562 Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection
11/23/1999US5989561 Recombinant poxvirus-calicivirus rabbit hemorrhagic disease virus (RHDV) compositions and uses
11/23/1999US5989553 Expression library immunization
11/23/1999US5989547 Leptospiral outer membrane proteins
11/23/1999US5989540 Modified adeno-associated virus vector capable of expression from a novel promoter
11/22/1999CA2238217A1 4e-bp3, a new member of the eukaryotic initiation factor 4e-binding protein family and use thereof
11/18/1999WO1999058701A1 Novel lentiviral packaging cells
11/18/1999WO1999058694A1 Methods of forming protein-linked lipidic microparticles, and compositions thereof
11/18/1999WO1999058691A2 Recombinant (alpha)-l-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
11/18/1999WO1999058683A2 BASB029 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM $i(NEISSERIA MENINGITIDIS)
11/18/1999WO1999058678A2 Antibodies to dendritic cells and human dendritic cell populations and uses thereof
11/18/1999WO1999058670A1 Ags proteins and nucleic acid molecules and uses therefor
11/18/1999WO1999058656A2 Sustained dna delivery from structural matrices
11/18/1999WO1999058646A1 Genetically-modified fibroblasts and the use thereof
11/18/1999WO1999058572A1 Binding molecules derived from immunoglobulins which do not trigger complement mediated lysis
11/18/1999WO1999058564A1 Frameshift mutants of beta-amyloid precursor protein and ubiquitin-b and their use
11/18/1999WO1999058560A2 Prostapin gene and protein and uses thereof
11/18/1999WO1999058559A2 Factors affecting tumor necrosis factor receptor releasing enzyme activity
11/18/1999WO1999058552A2 Peptides that ellicit t, cellular immunity
11/18/1999WO1999058156A1 Cancer prevention by selective delivery methods
11/18/1999WO1999058155A1 Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
11/18/1999WO1999058154A1 Protection from ionizing irradiation or chemotherapeutic drug damage by in vivo gene therapy
11/18/1999WO1999058152A1 Cationic lipids with disulphide bonds for the intracellular delivery of therapeutic substances
11/18/1999WO1999058151A2 Synthetic polyaminoacid complexes for delivery of nucleic acids to target cells
11/18/1999WO1999058146A1 ATTENUATED MUTANTS OF SALMONELLA WHICH CONSTITUTIVELY EXPRESS THE Vi ANTIGEN
11/18/1999WO1999058143A1 Utilization of interferon alpha 5 in the treatment of viral hepatopathies
11/18/1999WO1999058137A1 Bio-pharmaceutical preparation containing a live culture of bacillus and method for treating viral and bacterial infections as well as immuno-deficiency conditions
11/18/1999WO1999058134A1 Methods and compositions for nucleic acid delivery
11/18/1999WO1999050285A3 Production methods and uses of a retrovirus
11/18/1999WO1999049909A3 Revascularization apparatus having coaxial channeling and injecting means
11/18/1999WO1999047690A3 Multigene vectors
11/18/1999WO1999047673A3 Isolated mammalian membrane protein genes and related reagents
11/18/1999WO1999047150A9 A pharmaceutical composition containing ezrin mutated on tyrosine 353
11/18/1999WO1999046364A9 Vascular endothelial growth factor 2
11/18/1999WO1999046284A9 Molecules that home to various selected organs or tissues
11/18/1999WO1999046281A9 Novel polypeptides and nucleic acids encoding the same
11/18/1999WO1999042584A9 Apoptosis inducing molecule ii and methods of use
11/18/1999WO1999041416A3 Compositions comprising viruses and methods for concentrating virus preparations
11/18/1999WO1999036094A3 Composition and method for treating metastatic tumors or cancer induced by cells expressing sv40 tumor antigen
11/18/1999WO1999027098A3 A-33 related antigens and their pharmacological uses
11/18/1999CA2685270A1 Expression vectors for stimulating an immune response and methods of using the same
11/18/1999CA2331840A1 Polymeric system for delivery of nucleic acid material to target cells in biological systems
11/18/1999CA2331569A1 Protection from ionizing irradiation or chemotherapeutic drug damage by in vivo gene therapy
11/18/1999CA2331315A1 Identification of molecular interaction sites in rna for novel drug discovery
11/18/1999CA2330741A1 Methods of forming protein-linked lipidic microparticles, and compositions thereof
11/18/1999CA2328521A1 Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
11/18/1999CA2328518A1 Recombinant (alpha)-l-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
11/18/1999CA2328403A1 Basb029 polynucleotide(s) and polypeptides from neisseria meningitidis
11/18/1999CA2327549A1 Peptides that induce t cell responses
11/18/1999CA2327523A1 Frameshift mutants of beta-amyloid precursor protein and ubiquitin-b and their use
11/18/1999CA2324206A1 Prostapin gene and protein and uses thereof
11/18/1999CA2288993A1 Bio-pharmaceutical preparation containing a live culture of bacillus and method for treating viral and bacterial infections as well as immuno-deficiency conditions
11/17/1999EP0957172A2 Adenovirus-mediated gene transfer to cardiac and vascular smooth muscle
11/17/1999EP0956360A1 Poxvirus-based expression vectors containing heterologous inserts derived from lentiviruses
11/17/1999EP0956358A2 Cd95 regulatory gene sequences and transcription factors
11/17/1999EP0956352A1 A polynucleotide herpes virus vaccine
11/17/1999EP0956351A1 A tumor necrosis factor related ligand
11/17/1999EP0956339A1 Recombinant vascular endothelial cell growth factor d (vegf-d)
11/17/1999EP0956301A2 Il-12 gene expression and delivery systems and uses
11/17/1999EP0956299A1 Peptide antagonists of dp transcription factors
11/17/1999EP0956298A1 Snrnp sm proteins
11/17/1999EP0956289A1 Novel prokaryotic polynucleotides, polypeptides and their uses
11/17/1999EP0956052A1 Chimeric retrovirus/adenovirus system
11/17/1999EP0956051A1 Compositions and methods for pulmonary gene delivery
11/17/1999EP0956050A1 Novel lipid complexes for transferring at least a therapeutically active substance, in particular a polynucleotide into a target cell and use in gene therapy
11/17/1999EP0956046A2 Cellular vaccines and immunotherapeutics and methods for their preparation
11/17/1999EP0956045A2 Assembly-deficient herpesvirus vaccine
11/17/1999EP0956039A1 A method of treatment and prophylaxis
11/17/1999EP0956001A1 PREPARATION OF STABLE FORMULATIONS OF LIPID-NUCLEIC ACID COMPLEXES FOR EFFICIENT $i(IN VIVO) DELIVERY
11/17/1999EP0955999A1 Novel liposome complexes for increased systemic delivery
11/17/1999EP0955808A1 Human g-protein coupled receptor
11/17/1999CN1235609A Immunostimulatory nucleic acid molecules
11/17/1999CN1235555A Compounds and methods for treatment and diagnosis of mycobacterial infections
11/17/1999CN1235513A Nucleic acid and amino acid sequences ralating to helicobacter pylori and vaccine compositions thereof
11/16/1999US5986170 Murine model for human carcinoma
11/16/1999US5986083 Identifying single stranded rna target sequence and synthesizing complementary oligomer of mixed nucleosides with alternating racemic aryl- or lower alkyl-phosphonate linkages; has nuclease stability and enhanced hybridization binding
11/16/1999US5986078 DNA sequence encoding the tumor suppressor gene ING1
11/16/1999US5986069 Human haemopoietic maturation factor polypeptides
11/16/1999US5986058 Growth differentiation factor with amino acid sequences
11/16/1999US5986055 CDK2 interactions
11/16/1999US5986054 Genetic sequences and proteins related to alzheimer's disease
11/16/1999US5986053 Peptide nucleic acids complexes of two peptide nucleic acid strands and one nucleic acid strand
11/16/1999US5986052 Fusion polypeptide containing fragments of cartilage matrix protein and link protein
11/16/1999US5985847 Devices for administration of naked polynucleotides which encode biologically active peptides
11/16/1999US5985846 Gene therapy for muscular dystrophy
11/16/1999US5985662 By incubating hepatitis b virus or incubating cells, tissues, or a bodily fluid which contains hepatitis b virus with an antisense oligonucleotide of given nucleotide sequences under conditions where viral replication is inhibited