Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
09/1999
09/29/1999EP0944717A1 Method for producing recombinant adenovirus
09/29/1999EP0944715A1 Pressure-mediated intracellular delivery of molecules or microparticles
09/29/1999EP0944651A2 Genes amplified in cancer cells
09/29/1999CN1230222A PTX-sensitive G proteins, prodn. and use thereof
09/29/1999CN1230220A Therapy for 'alpha'-galactosidase deficiency
09/28/1999US5959096 For anticarcinogenic/antitumor/antiproliferative agents; antiinflammatory agents; treatment of psoriasis, and glioblastoma, bladder, breast, lung and tumor cancer
09/28/1999US5959075 Testis-specific insulin homolog polypeptides
09/28/1999US5958901 Delivery of anionic macromolecules into cells.
09/28/1999US5958895 Delivering to a mammalian cell an effective amount of a modified gene encoding an hsv gd antigen lacking a functional native signal peptide, said modified gene under the control of regulatory sequences directing expression of said antigen
09/28/1999US5958894 Complex with nucleic acid, cell entry, drug delivery
09/28/1999US5958893 Dna molecule
09/28/1999US5958892 2-methoxyestradiol-induced apoptosis in cancer cells
09/28/1999US5958891 Administering vector comprising gene encoding dust mite allergen by intramuscular injection to prevent airway hyperreactivity or airway inflammation
09/28/1999US5958880 Feline Fc epsilon receptor alpha chain proteins and therapeutic uses thereof
09/28/1999US5958774 Generally, the invention relates to a method for gene transfer into cells activated from a quiescent state, in particular hematopoietic stem cells, and the cells thus obtained.
09/28/1999US5958772 Antisense inhibition of cellular inhibitor of apoptosis-1 expression
09/28/1999US5958771 Oligonucleotide from 8 to 30 nucleotides in length; for diagnosis and therapy; antitumor/antiinflammatory agents
09/28/1999US5958769 Compositions and methods for mediating cell cycle progression
09/28/1999US5958768 Compositions for the treatment and diagnosis of infections of rev-binding primate lentiviruses are provided. the primate lentiviruses, including human immunodeficiency virus (hiv) type 1 (hiv-1), and type 2 (hiv-2) and siv are genetically,
09/28/1999US5958767 Engraftable human neural stem cells
09/28/1999US5958764 Specific expression vectors and methods of use
09/28/1999US5958731 Cell junction PDZ protein
09/28/1999US5958726 Polynucleotide sequence of clone h84924 accession number atcc 98028; has signal sequence; for diagnosis and treatment of related diseases
09/28/1999US5958720 Mch2, an apoptotic cysteine protease, and compositions for making and methods of using the same
09/28/1999US5958718 Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfunction
09/28/1999US5958711 Contacting a sample from a subject with an agent specific for said complex and determining interaction between said complex and said agent as a determination of said disorder
09/28/1999US5958709 Processes for identifying compounds that bind to the human Y4 receptor
09/28/1999US5958706 Fine magnetic particles containing useful proteins bound thereto, process for producing the same, and use thereof
09/28/1999US5958682 Virus-directed enzyme prodrug therapy for treating tumor cells consisting of a viral vector encoding bacterial nitroreductase capable of converting a prodrug into a cytotoxic drug operably linked to a promoter; and the prodrug
09/28/1999US5958425 Viral vaccines
09/28/1999US5958424 Recombinant chicken anemia virus particle
09/28/1999US5958404 Grafting cells for treatment of disease and diabetes
09/28/1999US5958403 Localized immunosuppression by insertion of nucleic acid sequence encoding cytotoxic t-cell lymphocyte antigen-immunoglobulin operably linked to promoter into an islet cell, ex vivo
09/28/1999US5958400 Isolated polypeptide comprising specified amino acid sequence
09/28/1999CA2187803C Methods of treating disease using sertoli cells and allografts or xenografts
09/27/1999CA2266805A1 Cell-based gene therapy in the treatment of pulmonary disorders
09/27/1999CA2227425A1 Cell-based gene therapy
09/26/1999CA2264260A1 Polynucleotide molecules encoding neospora proteins
09/24/1999CA2249660A1 Novel compounds
09/23/1999WO1999047708A1 Antisense modulation of pecam-1
09/23/1999WO1999047707A1 Antisense modulation of lfa-3
09/23/1999WO1999047690A2 Multigene vectors
09/23/1999WO1999047687A1 Enhanced anti-tumor immunity
09/23/1999WO1999047678A2 Interferon alpha plasmids and delivery systems, and methods of making and using the same
09/23/1999WO1999047675A1 Mu-1, member of the cytokine receptor family
09/23/1999WO1999047674A2 Compounds and methods for therapy and diagnosis of lung cancer
09/23/1999WO1999047673A2 Isolated mammalian membrane protein genes and related reagents
09/23/1999WO1999047672A1 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
09/23/1999WO1999047669A2 Human nucleic acid sequences from tissue of breast tumors
09/23/1999WO1999047668A2 Nucleic acid which codes for tumor suppressor proteins, tumor suppressor proteins, a method for the production thereof, an antibody against tumor suppressor proteins, and the use of these substances
09/23/1999WO1999047662A1 Staphylococcus aureus genes and polypeptides
09/23/1999WO1999047660A1 Retroviral packaging cell line
09/23/1999WO1999047659A1 Use of human serum resistant vector particles and cell lines for human gene therapy
09/23/1999WO1999047655A2 Human nucleic acid fragments with heightened expression in normal breast tissue
09/23/1999WO1999047653A1 Suicide gene therapy system for the treatment of brain tumours
09/23/1999WO1999047641A1 Compositions and methods for gene-based vaccines to provoke t cell responses
09/23/1999WO1999047639A2 Staphylococcus aureus genes and polypeptides
09/23/1999WO1999047638A2 Mutations in mitotic check point genes and methods of diagnosis
09/23/1999WO1999047564A1 Fas-associated polypeptides
09/23/1999WO1999047563A2 Ribonucleotide polypeptides containing metal
09/23/1999WO1999047562A1 Nephrin gene and protein
09/23/1999WO1999047558A2 T cell costimulatory proteins, sequences and uses thereof
09/23/1999WO1999047556A2 Novel heparin-induced ccn-like molecules and uses therefor
09/23/1999WO1999047540A1 95 human secreted proteins
09/23/1999WO1999047538A1 Cytokine receptor common gamma chain like
09/23/1999WO1999047180A1 Chimeric adenoviral vectors for targeted gene delivery
09/23/1999WO1999047179A1 COMPOSITIONS AND METHODS FOR ENHANCED ANTIGEN DELIVERY TO ANTIGEN PRESENTING CELLS $i(IN VIVO)
09/23/1999WO1999047178A1 Novel complementing receptor-ligand pairs and adoptive immunotherapy using same
09/23/1999WO1999047177A1 Gene therapy vector with osteocalcin promoter and genes for bone morphogenic proteins or growth factors
09/23/1999WO1999047169A1 Methods to provoke anti-cancer immune responses
09/23/1999WO1999047152A2 Use of dipeptidyl peptidase (dpp4) of fibroblast activating protein alpha for suppressing the malignant phenotype of cancer cells
09/23/1999WO1999047150A2 A pharmaceutical composition containing ezrin mutated on tyrosine 353
09/23/1999WO1999047147A1 nrdG
09/23/1999WO1999047102A2 Methods for enhanced antigen presentation on antigen-presenting cells and compositions produced thereby
09/23/1999WO1999046988A1 Compositions and methods for antigen-specific vaccination
09/23/1999WO1999041369A3 Genetic vaccine vector engineering
09/23/1999WO1999041355A3 Hiv chemokines
09/23/1999WO1999039740A8 Sensitizing cells to compounds using lipid-mediated gene and compound delivery
09/23/1999WO1999038955A3 Mutant herpes simplex viruses and uses thereof
09/23/1999WO1999038821A3 Transfecting compositions sensitive to reducing conditions, pharmaceutical compositions containing them, and their applications
09/23/1999WO1999037774A8 Differentiation-associated sequences and methods of use therefor
09/23/1999WO1999036558A3 Viral vectors encoding neurofilament heavy proteins and their use
09/23/1999WO1999036533A3 Nucleic acid corresponding to mutation associated with cholestasis syndromes
09/23/1999WO1999036433A3 Materials and methods for treating oncological disease
09/23/1999WO1999036082A3 The use of increased neurofilament protein levels as protection and therapy against neurodegeneration with oxidative stress involvement
09/23/1999WO1999032620A9 Insulin-like growth factor binding protein fragments and the utilization thereof
09/23/1999WO1999029304A9 Method for high supercoiled dna content microspheres
09/23/1999DE19813839A1 Human nucleic acid sequences and protein products from tumor breast tissue, useful for breast cancer therapy
09/23/1999DE19813835A1 Human nucleic acid sequences and protein products from normal breast tissue, useful for breast cancer therapy
09/23/1999CA2625284A1 Modulators of the function of receptors of the tnf/ngf receptor family
09/23/1999CA2324138A1 Novel complementing receptor-ligand pairs and adoptive immunotherapy using same
09/23/1999CA2323897A1 Suicide gene therapy system for the treatment of brain tumours
09/23/1999CA2323761A1 95 human secreted proteins
09/23/1999CA2323746A1 T cell costimulatory proteins, sequences and uses thereof
09/23/1999CA2323724A1 Staphylococcus aureus genes and polypeptides
09/23/1999CA2323637A1 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
09/23/1999CA2323604A1 Interferon alpha plasmids and delivery systems, and methods of making and using the same
09/23/1999CA2323112A1 Multigene vectors
09/23/1999CA2323095A1 Metal-containing ribonucleotide polypeptides
09/23/1999CA2323093A1 Compounds and methods for therapy and diagnosis of lung cancer