Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
01/2000
01/11/2000US6013453 Libraries of dna sequences encoding zinc finger binding motifs for display on a viral particle, together with methods of designing zinc finger binding polypeptides for binding to a target sequence
01/11/2000US6013448 Pancreas-derived serpin
01/11/2000US6013268 Methods for enhancement of protective immune responses
01/11/2000US6013258 Immunogenic peptides from the HPV E7 protein
01/11/2000US6013257 Neurotactin and uses therefor
01/11/2000US6013240 Nucleic acid containing composition, preparation and uses of same
01/11/2000US6012375 Aircraft infrared guided defense missile system
01/07/2000CA2276791A1 Use of adenoviral e4 reading frames to improve expression of a gene of interest
01/06/2000WO2000000644A1 Uses of dna-pk
01/06/2000WO2000000629A1 High efficiency retroviral vectors that contain none of viral coding sequences
01/06/2000WO2000000628A1 Replication-defective recombinant adenovirus with mutated major late promoter
01/06/2000WO2000000604A1 Methods and compositions for modulating spermatogenesis
01/06/2000WO2000000603A2 Modularly constructed rna molecules having two sequence region types
01/06/2000WO2000000504A1 Antisense modulation of tnfr1 expression
01/06/2000WO2000000503A1 Human az-1 gene, variants thereof and expressed gene products
01/06/2000WO2000000224A2 Method for transporting a molecular substance in predetermined areas of eucaryotic cells
01/06/2000WO2000000218A1 Mucosal targeting immunisation
01/06/2000WO1999058656A3 Sustained dna delivery from structural matrices
01/06/2000WO1999055900A3 Gcp
01/06/2000WO1999055855A3 Neuropilin antisense oligonucleotide sequences and methods of using same to modulate cell growth
01/06/2000WO1999055364A3 Proteins that direct the secretion of virulence proteins and vaccines comprising them
01/06/2000WO1999044629A3 Utilization of cd137 in order to promote the proliferation of peripheral monocytes
01/06/2000WO1999029310A3 Regulation of t cell-mediated immunity by tryptophan and its analogs
01/06/2000WO1999026663A3 Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
01/06/2000CA2337823A1 Mucosal targeting immunisation
01/06/2000CA2332181A1 Replication-defective recombinant adenovirus with mutated major late promoter
01/06/2000CA2332175A1 Modularly constructed rna molecules having two sequence region types
01/06/2000CA2331779A1 Methods and compositions for modulating spermatogenesis
01/06/2000CA2311119A1 Method for transporting a molecular substance in predetermined areas of eucaryotic cells
01/05/2000EP0969091A2 Leptin receptor gene-related protein
01/05/2000EP0968724A1 Use of viral vectors for treatment of the injured peripheral and central nervous system
01/05/2000EP0968299A1 Rapid production of autologous tumor vaccines by using hsv amplicon vectors
01/05/2000EP0968298A2 Adenovirus vectors specific for cells expressing carcinoembryonic antigen and methods of use thereof
01/05/2000EP0968296A2 Expression vector for the permanent expression of foreign dna
01/05/2000EP0968295A1 Vectors having enhanced expression and methods of making and uses thereof
01/05/2000EP0968284A2 An improved method for the production and purification of adenoviral vectors
01/05/2000EP0968281A2 An oncolytic/immunogenic complementary-adenoviral vector system
01/05/2000EP0968277A1 Filtration method for separating viruses
01/05/2000EP0968276A1 NOVEL clpL
01/05/2000EP0968227A1 Dimeric cationic lipids on dicystine basis
01/05/2000EP0968225A1 NOVEL spsB
01/05/2000DE19819476C1 Polypeptid mit immunogenen Eigenschaften und veränderten biologischen Funktionen eines Proteins Polypeptide having immunogenic properties and altered biological function of a protein
01/05/2000CN1240480A Methods and compositions for delivery and expression of interferon-'alpha' nucleic acids
01/05/2000CN1240359A Therapeutic use of an agent that stimulates no or prostacyclin production and delivery device
01/05/2000CN1240358A Use of CNTF (ciliary neurotrophic factor) receptor activators for the treatment of obesity
01/04/2000US6011018 Regulated transcription of targeted genes and other biological events
01/04/2000US6010908 Gene therapy by small fragment homologous replacement
01/04/2000US6010906 Antisense modulation of Jun N-terminal kinase kinase-1 expression
01/04/2000US6010881 Useful to screen compounds for antibiotic activity. polynucleotides that encode ribg polypeptides
01/04/2000US6010878 Interleukin-1 β converting enzyme like apoptotic protease-6
01/04/2000US6010877 cDNA clone HE8CS41 that encodes a novel 7-transmembrane receptor
01/04/2000US6010874 Early onset alzheimer's disease gene and gene products
01/04/2000US6010872 Recombinant production of TGF-β type III receptor (betaglycan) polypeptides
01/04/2000US6010712 Therapeutic use of bFGF to treat conditions involving adhesion of cytotoxic white cells to endothelium
01/04/2000US6010700 Polypeptides p57 or p9.5 of Borna disease virus and their use for diagnosis and immunization
12/1999
12/30/1999DE19829005A1 A method to transport molecular substances inside eukaryotic cell
12/30/1999CA2244211A1 Novel compounds
12/29/1999WO1999067397A1 De novo dna cytosine methyltransferase genes, polypeptides and uses thereof
12/29/1999WO1999067395A1 Nucleic sequence and deduced protein sequence family with human endogenous retroviral motifs, and their uses
12/29/1999WO1999067393A2 Aav scleroprotein, production and use thereof
12/29/1999WO1999067388A1 Antisense oligonucleotide inhibiting the expression of il-10 protein
12/29/1999WO1999067382A2 Angiopoietin-like growth factor sequences
12/29/1999WO1999067381A1 Treatment of staphylococcus infections
12/29/1999WO1999067380A1 c-Cbl SUPPRESSION OF NEOPLASTIC TRANSFORMATION
12/29/1999WO1999067379A2 Structured antisense nucleic acid molecules
12/29/1999WO1999067372A1 Mutated herpes simplex virus type 1 thymidine kinases and uses thereof
12/29/1999WO1999067288A1 Tumor antigen peptides originating in cyclophilin b
12/29/1999WO1999066959A2 Compositions and methods for delivery of genetic material for altering neuronal growth, regeneration, and survival
12/29/1999WO1999066946A1 Compositions and methods for inducing apoptosis in e6-expressing cells
12/29/1999WO1999066879A2 Systemic immune activation method using nucleic acid-lipid complexes
12/29/1999WO1999060147A3 Targeted delivery through a cationic amino acid transporter
12/29/1999WO1999057320B1 Antisense modulation of cd40 expression
12/29/1999WO1999057140A3 Growth-associated protease inhibitor heavy chain precursor
12/29/1999WO1999049774A3 Methods for the diagnosis and treatment of lung cancer
12/29/1999WO1999042564A3 Apoptotic cell-mediated antigen presentation to dendritic cells
12/29/1999WO1999037755A3 The use of consensus sequences for targeted homologous gene isolation and recombination in gene families
12/29/1999EP0967289A1 Improvements in gene therapy using compositions comprising a polynucleotide and a nuclease inhibitor
12/29/1999EP0967284A1 Phosphodiesterases
12/29/1999EP0967279A1 Helicobacter pylori cytotoxin useful for vaccines and diagnostics
12/29/1999EP0967276A2 Anti-tumor agent comprising salmosin
12/29/1999EP0966685A1 Protein fragment complementation assays to detect biomolecular interactions
12/29/1999EP0966536A1 Factor x analogues with a modified protease cleavage site
12/29/1999EP0966534A1 Compositions and methods for elimination of unwanted cells
12/29/1999EP0966532A1 Biological material for treating a mammal by antibody gene transfer and pharmaceutical composition containing same
12/29/1999EP0966530A2 Secreted proteins and polynucleotides encoding them
12/29/1999EP0966484A1 Neurotactin and uses therefor
12/29/1999EP0966480A2 Cysteine-depleted peptides recognized by a3-restricted cytotoxic lymphocytes, and uses therefor
12/29/1999EP0868716A4 Method for recovering data from disk with magneto-resistive head in presence of thermal asperities
12/29/1999EP0822993B1 Diagnostic methods and gene therapy using reagents derived from the human metastasis suppressor gene kai1
12/29/1999EP0774005B1 Surface expression of enzyme in gene directed prodrug therapy
12/29/1999EP0751788B1 Composition including a recombinant plasmid, and uses thereof as a vaccine and drug
12/29/1999EP0668781B1 Lymphokine gene therapy of cancer in combination with tumor antigens
12/29/1999EP0564645B1 Transformant cells for the prophylaxis or treatment of diseases caused by viruses, particularly pathogenic retroviruses
12/29/1999CN1240000A Polypeptides encoded by human lipase-like gene, compositions and methods
12/29/1999CA2618288A1 Antisense oligonucleotide constructs based on .beta.-arabinofuranose and its analogues
12/29/1999CA2331923A1 Nucleic sequence and deduced protein sequence family with human endogenous retroviral motifs, and their uses
12/29/1999CA2331919A1 Structured antisense nucleic acid molecules
12/29/1999CA2331761A1 Tumor antigen peptides originating in cyclophilin b
12/29/1999CA2330026A1 Compositions and methods for delivery of agents for altering neuronal growth, regeneration, and survival
12/28/1999US6008336 Compacted nucleic acids and their delivery to cells