Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
02/2001
02/14/2001EP0618924B1 Hbv amplifier probes for use in solution phase sandwich hybridization assays
02/14/2001EP0576590B1 Response element compositions and assays employing same
02/14/2001EP0520014B1 Multichromophore fluorescent probes
02/14/2001CN1284082A Self-addressable self-assembling microelectronic integrated systems, component devices, mechanisms, methods, and procedures for molecular biological analysis and diagnostics
02/14/2001CN1283692A Protein associated with olfaction of human nerve cell and its coding sequence
02/13/2001US6187996 Plant promoter comprising a G-box element, GCCACGTGCC or GCCACGTGAG, and an application thereof
02/13/2001US6187914 Solid phase synthesis of oligonucleotides using electrochemically labile protecting groups which can be removed by creating potential difference between working electrode and counterelectrode
02/13/2001US6187913 Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method
02/13/2001US6187642 Method and apparatus for making mosfet's with elevated source/drain extensions
02/13/2001US6187587 Nucleotide sequences; for diagnosis and treatment of related disorders
02/13/2001US6187586 Nucleotide sequence of compound which inhibits expression of human serine/threonine kinase involved in signal transduction; diagnosis, prophylaxis, and therapy of related diseases
02/13/2001US6187557 Nucleotide sequences coding modulator protein; for the diagnosis and treatment of defects in apotosis
02/13/2001CA2127117C Dna encoding a human serotonin receptor (5-ht4b) and uses thereof
02/08/2001WO2001009390A1 Tenascin-c nucleic acid ligands
02/08/2001WO2001009385A2 Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids
02/08/2001WO2001009161A1 Drug target isogenes: polymorphisms in the solute carrier family 6_neurotransmitter transporter, serotonin_, member 4 gene
02/08/2001WO2001009160A1 Nucleic acid ligands to cd40ligand
02/08/2001WO2001009159A1 Nucleic acid ligands to hepatocyte growth factor/scatter factor (hgf/sf) or its receptor c-met and to integrins
02/08/2001WO2001009157A1 High affinity vascular endothelial growth factor (vegf) receptor nucleic acid ligands and inhibitors
02/08/2001WO2001009156A1 HIGH AFFINITY TGFη NUCLEIC ACID LIGANDS AND INHIBITORS
02/08/2001WO2001008794A1 Method and device for the parallel manufacture of oligonucleotides
02/08/2001WO2001008707A2 Conjugates and methods for the production thereof, and their use for transporting molecules via biological membranes
02/08/2001DE19935303A1 Oligonukleotide zur Inhibierung der Expression von humanem eg5 Oligonucleotides for inhibiting the expression of human Eg5
02/08/2001DE19935302A1 Konjugate und Verfahren zu deren Herstellung sowie deren Verwendung zum Transport von Molekülen über biologische Membranen Conjugates and methods for their preparation and their use for transporting molecules across biological membranes
02/08/2001CA2697207A1 Polymorphisms in the human mdr-1 gene and their use in diagnostic and therapeutic applications
02/08/2001CA2381004A1 Nucleic acid ligands to hepatocyte growth factor/scatter factor (hgf/sf) or its receptor c-met and to integrins
02/08/2001CA2380837A1 High affinity tgf.beta. nucleic acid ligands and inhibitors
02/08/2001CA2380545A1 Nucleic acid ligands to cd40ligand
02/08/2001CA2380535A1 High affinity vascular endothelial growth factor (vegf) receptor nucleic acid ligands and inhibitors
02/08/2001CA2380473A1 Tenascin-c nucleic acid ligands
02/08/2001CA2379828A1 Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids
02/07/2001EP1074626A2 Genes for lysine biosynthetic system derived from thermophilic bacteria
02/07/2001EP1074559A1 Peptide nucleic acids
02/07/2001EP1073732A2 Nucleoside triphosphates and their incorporation into ribozymes
02/07/2001EP1073710A2 Non-stochastic generation of genetic vaccines and enzymes
02/07/2001EP1073683A1 G-csf receptor agonist antibodies and screening method therefor
02/07/2001EP1073668A2 Solution phase biopolymer synthesis
02/07/2001EP1073464A1 Monoclonal antibodies with reduced immunogenicity
02/07/2001EP0562025B1 Compounds and their use in a binary synthesis strategy
02/07/2001EP0462207B1 T-pa mutants resistant to inhibition by their cognate inhibitors
02/06/2001US6184389 Feature a plurality of functional groups attached to backbone and phosphoramidate sites
02/06/2001US6184369 Anti-viral guanosine-rich oligonucleotides
02/06/2001US6184364 Dehydrating uridine to form 2,2'-anhydrouridine, converting to unprotected 2'-azido-2'-deoxyuridine, iodinating to form 5-iodo-2'-azido, 2'-deoxyuridine, then reducing to 5-iodo, 2'-amino-2'-deoxyuridine; selex ligands
02/06/2001US6184352 Adseverin protein
02/06/2001US6184347 Selecting and applying a reactive wash solution that is not reactive to growing polymer but deactives unused reactive agents and is miscible with reaction solution; removes reaction solution from surface of solid phase
02/06/2001US6184212 Antisense modulation of human mdm2 expression
02/06/2001US6184211 Inhibition of DNA methyltransferase
02/06/2001US6184025 Nucleotide sequences for the detection and diagnosis of viral diseases
02/06/2001US6183967 Nucleic acid ligand inhibitors to DNA polymerases
02/06/2001US6183751 Unique associated Kaposi's Sarcoma virus sequences and uses thereof
02/06/2001CA2025491C Methods and materials for phe a feedback inhibition resistance
02/01/2001WO2001007655A1 Antisense modulation of shp-2 expression
02/01/2001WO2001007645A2 Method for marking solid, liquid and gaseous substances
02/01/2001WO2001007624A2 Dna sequences which are suited for specifically detecting pseudomonas putida kt2440
02/01/2001WO2001007603A1 Cloning of nps45: a gene encoding a putative translation initiation/stabilization factor
02/01/2001WO2001007602A2 Oligonucleotides for inhibiting the expression of human eg5
02/01/2001WO2001007459A1 29 human secreted proteins
02/01/2001WO2001007456A1 Antisense modulation of jun n-terminal kinase kinase-1 expression
02/01/2001WO2001007455A1 Novel bicyclonucleoside analogues
02/01/2001WO2000059917A3 Information-carrying and information-processing polymers
02/01/2001WO2000050432A3 Synthesis of labelled oligonucleotides on solid-supports
02/01/2001DE19935204A1 Labelling and masking of incomplete products in the production of polymeric compounds, especially oligonucleotides, comprises the addition of reactive functional compounds during the synthesis
02/01/2001DE19935088A1 DNA-Sequenzen, die sich zum spezifischen Nachweis von Pseudomonas putida KT2440 eignen DNA sequences that are suitable for the specific detection of Pseudomonas putida KT2440
02/01/2001CA2693274A1 Peptide acceptor ligation methods
02/01/2001CA2383690A1 29 human secreted proteins
02/01/2001CA2380192A1 Oligonucleotides for inhibiting the expression of human eg5
02/01/2001CA2377810A1 Method for marking solid, liquid and gaseous substances
01/2001
01/31/2001EP1072679A2 Method of producing nucleic acid molecules with reduced secondary structure
01/31/2001EP1071812A1 A method, reagent solution and kits for dna sequencing
01/31/2001EP1071764A1 ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF INTEGRIN $g(a) v?-SUBUNIT EXPRESSION
01/31/2001EP1071754A1 Recombinant secoisolariciresinol dehydrogenase, and methods of use
01/31/2001EP1071706A1 Rapidly degrading gfp-fusion proteins and methods of use
01/31/2001EP1071701A1 Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof
01/31/2001EP1071700A1 Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
01/31/2001EP1071699A1 Enhanced antisense modulation of icam-1
01/31/2001EP1071698A1 Nucleic acid sequences and proteins associated with aging
01/31/2001EP1071696A1 Programmed cell death and caspase-12
01/31/2001EP1071695A1 Endotoxin reduction in nucleic acid purification
01/31/2001EP1071691A1 Method for isolating and purifying nucleic acids
01/31/2001EP1071459A1 Methods to provoke anti-cancer immune responses
01/31/2001EP1071443A1 Isolated peptides corresponding to amino acid sequences of ny-eso-1, wherein bind to mhc class i and mhc class ii molecules, and uses thereof
01/31/2001EP1071334A1 A method for efficient and highly selective control of microorganisms
01/31/2001EP1071325A1 Compositions and methods for antigen-specific vaccination
01/31/2001CN1281898A Human zinc finger protein isomer and its code sequence
01/31/2001CN1281897A Human thioredoxin related protein and its code sequence
01/31/2001CN1281896A Human nuclear receptor factor protein an its code sequence
01/31/2001CN1281895A Human mitochondrial solute carrier protein isomer and its code sequence
01/31/2001CN1281862A Three-chain formed oligonucleotide capable of inhibiting platelet derived growth factor gene expression and its application
01/30/2001US6180778 Process for the separation of double-stranded/single-stranded nucleic acid structures
01/30/2001US6180777 Synthesis of branched nucleic acids
01/30/2001US6180776 MTS2 gene
01/30/2001US6180771 Given nucleotide sequence; useful for pharmaceutical administration or methods of diagnosing sensitivity to house dust mites
01/30/2001US6180770 Containing a covalently attached nucleic acid molecule capable of copolymerization with a second monomer unit to form a polymerized layer useful in hybridization assays; beta-cyanoethyl phosphoramidite reagent
01/30/2001US6180766 Nucleosides and oligonucleotides containing boron clusters
01/30/2001US6180403 Antisense inhibition of tumor necrosis factor alpha converting enzyme (TACE) expression
01/30/2001US6180399 Synthetic rna having endonuclease activity and altered substrate binding site; for multifunctional enzyme
01/30/2001US6180380 Cloning of a new member of the serine threonine kinase family
01/30/2001US6180371 Modified factor VIII
01/30/2001US6180362 Peptides which inhibit ras protein activity, their preparation and use
01/30/2001US6180360 Process of producing β-lactam antibiotics applying micro-organisms with increased ligase activity