Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
01/2001
01/30/2001US6180353 Nucleotide sequences associated with suppression of transcription binding protein associated with apoptosis; for the treatment and prevention defects associated with apoptosis
01/30/2001US6180352 Nucleic acid mediated electron transfer
01/30/2001US6180349 Quantitative PCR method to enumerate DNA copy number
01/30/2001US6180345 Process for simultaneous preparation of sex specific and gender-neutral semisynthetic amplicons useful for sex determination
01/30/2001US6180141 Composite gel microparticles as active principle carriers
01/30/2001US6180109 Nucleotide and polypeptide sequences of pestivirus strains
01/30/2001US6180104 Can be used such as nucleotide probes, combining with foreign dna sequences to produce novel t-cell receptors, which can be used in an analogous manner as antibodies, or constructs can be provided which provide for extrachromosomal elements
01/30/2001CA2177604C Labelling of nucleic acid analogue-peptide chimerae
01/30/2001CA2022610C Human gp130 protein
01/25/2001WO2001006496A1 Inorganic permeation layer for micro-electric device
01/25/2001WO2001005993A1 Cellular absorption of dna
01/25/2001WO2001005954A1 Antisense modulation of liver glycogen phosphorylase expression
01/25/2001WO2001005801A1 Novel nucleic acid base pair
01/25/2001WO2000053785A3 Method to improve translation of polypeptides by using untranslated regions from heat-shock proteins
01/25/2001DE19934573A1 Labeling and identifying solid, liquid or gaseous substances, comprises using a complementary pair of nucleic acid sequences for each substance
01/25/2001DE19933506A1 Zelluläre Aufnahme von DNA Cellular uptake of DNA
01/25/2001CA2379762A1 Inorganic permeation layer for micro-electric device
01/24/2001EP1070141A1 Immediate early genes and methods of use therefor
01/24/2001EP1070079A2 Method for the production of pentopyranosyl nucleosides
01/24/2001EP1069903A1 Novel nucleoside analogs and uses in treating disease
01/24/2001EP0543942B1 Homogeneous assay system
01/24/2001CN1281462A Isolation of nucleic acids
01/24/2001CN1281366A Prevention and treatment of amyloidogenic disease
01/24/2001CN1281047A Human limb deformation protein and its coding sequence
01/24/2001CN1281046A Human growth or deformation dependent protein and its coding sequence
01/24/2001CN1281045A Human fibrous surface structure subunit protein and its coding sequence
01/24/2001CN1281044A Human translation initiation factor protein and its coding sequence
01/24/2001CN1281043A Human early endosome antigen protein isomer and its coding sequence
01/24/2001CN1281042A Human carboxylpeptidase protein and its coding sequence
01/24/2001CN1281041A Human complement component subunit chain protein isomer and its coding sequence
01/24/2001CN1281040A Human actin associated protein compound subunit protein and its coding sequence
01/24/2001CN1281039A Human ribosome subunit protein and its coding sequence
01/23/2001US6177558 During solid phase synthesis of nucleic acids, peptides and peptide nucleic acids on an open environment solid support, the polar aprotic solvent selected from mono- and dinitriles, glymes, diglymes, triglymes, and trimethylphosphates
01/23/2001US6177557 Nucleotide sequences which bind preferential proteins; for use as coagulants and in prevention of neovascularization
01/23/2001US6177555 Fluorescent nucleotide sequence complex; for the dectection of preferential sequences in sample
01/23/2001US6177401 Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
01/23/2001US6177278 Nucleic acid purification and process
01/23/2001US6177273 Antisense modulation of integrin-linked kinase expression
01/23/2001US6177257 Immunoassay diagnosis of susceptibility to atherosclerosis by analyzing blood for presence of enzyme using polyclonal or monoclonal antibodies; elevated levels are indicative of susceptibility
01/23/2001US6177251 Separating mammalian nucleic acid from sample by removing particulate matter from sample in a lysis buffer, then separating out nucleic acids; buffer does not lyse bacterial cells; screening for mutation in gene indicative of cancer
01/23/2001US6177250 Nucleic acid mediated electron transfer
01/23/2001US6177248 Detecting expression of at least one gene down-stream from wt1 and comparing to wild type cells; a difference suggests mutation; diagnosis of cancer/tumor
01/23/2001US6177246 Contacting a tissue or cell with an oligonucleotide of defined nucleotide sequence which hybridizes to nucleic acid encoding abnormally expressed beta-amyloid precursor protein; prophylaxis and treatment of alzheimer's disease
01/23/2001US6177243 Nucleic acid sequence detection employing amplification probes
01/23/2001US6177242 Genomic DNA fragments containing regulatory and coding sequences for the β2-subunit of the neuronal nicotinic acetylcholine receptor and transgenic animals made using these fragments or mutated fragments
01/23/2001CA2017369C Modified phosphoramidite process for the production or modified nucleic acids
01/18/2001WO2001004325A1 Nucleotide sequences for the tal gene
01/18/2001WO2001004287A1 A method for preparing modified polypeptides
01/18/2001WO2001004129A1 Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
01/18/2001CA2377589A1 Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
01/18/2001CA2348448A1 Nucleotide sequences for the tal gene
01/17/2001EP1068357A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
01/17/2001EP1068356A1 Addressable protein arrays
01/17/2001EP1068308A1 Secreted proteins and polynucleotides encoding them
01/17/2001EP1068216A2 Libraries of oligomers labelled with different tags
01/17/2001EP1067969A1 Polyene macrolide derivatives, use for vectoring molecules
01/17/2001EP1067940A1 Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
01/17/2001EP1067917A2 Method of treating dopaminergic and gaba-nergic disorders
01/17/2001EP0792374B1 Self-quenching fluorescence probe and method
01/17/2001CN1060781C Phosphonomonoester nucleic acids, process for treir preparation, and their use
01/16/2001US6175006 Automated system for polynucleotide synthesis and purification
01/16/2001US6175004 Process for the synthesis of oligonucleotides incorporating 2-aminoadenosine
01/16/2001US6175001 Derivatized at c5 to contain functional group that mimics the property of naturally occurring amino acid; for use in polymerase chain reactions
01/16/2001US6174998 C-nucleoside derivatives and their use in the detection of nucleic acids
01/16/2001US6174995 Amino acid sequences of chemokine beta-4 and monocyte chemotactic protein-4; anticarcinogenic/antitumor agents; antifibrotic/antiarthritic/antiinflammatory agents; treatment of chronic infections, autoimmune disorders, psoriasis
01/16/2001US6174869 Method for enhancing neurone survival and agents useful for same
01/16/2001US6174868 Compositions and methods for treatment of hepatitis C virus-associated diseases
01/16/2001US6174717 Elicitor of the hypersensitive response in plants
01/16/2001US6174709 Accumulation of nucleotide sequences; forming a mixture of sample and preferential oligonucleotides, accumulating target nucleotide sequences by polymerase chain reaction
01/16/2001US6174676 Cytokine-stress- and oncoprotein-activated human protein kinase kinases
01/16/2001US6174669 Making full-length cdna libraries utilizing method of labeling of the 5' cap site
01/16/2001CA1341166C Antigenic proteins and vaccines containing them for prevention of coccidiosis
01/11/2001WO2001002608A1 Oligonucleotides incorporating both 2-aminoadenine and 5-substituted pyrimidines
01/11/2001WO2001002593A2 Control of gene expression in eukaryotic cells
01/11/2001WO2001002538A1 Substrates for nucleic acid immobilization onto solid supports
01/11/2001WO2001002423A2 2'-guanidinyl-substituted oligonucleotides and gene expression modulation therewith
01/11/2001WO2001002419A1 C3'-methylene hydrogen phosphonate oligomers and related compounds
01/11/2001WO2001002417A1 Nucleotide monomer containing six-membered azarsugar and antisense oligomers thereof
01/11/2001WO2001002416A1 Dinucleotide crystals
01/11/2001WO2001002415A1 C3'-methylene hydrogen phosphonate monomers and related compounds
01/11/2001WO2000066604A3 L-ribo-lna analogues
01/11/2001WO2000029561A8 Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope
01/11/2001CA2377932A1 Control of gene expression in eukaryotic cells
01/10/2001EP1067134A2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
01/10/2001EP1066531A1 Micro system and method for field manipulation of particules
01/10/2001EP1066506A1 Method and apparatus for synthesis of arrays of dna probes
01/10/2001EP1066396A1 Nucleic acid transfer vectors, compositions containing same and uses
01/10/2001EP1066311A1 Compositions and methods for the identification of lung tumor cells
01/10/2001EP1066310A1 Neokine protein and nucleic acid molecules and uses therefor
01/10/2001EP1066308A1 Improved methods for synthesis of oligonucleotides
01/10/2001EP0862439A4 Ligands to enhance cellular uptake of biomolecules
01/10/2001EP0556301B1 Incorporation of multiple reporter groups on synthetic oligonucleotides
01/10/2001CN1279687A Bi-and tri-cyclic nucleoside, nucleotide and oligonucleotide analoguse
01/10/2001CN1279686A Inhibitors of nucleoside metabolism
01/10/2001CN1279243A Cancer suppressing action of antisense nucleic acid to leukemia gene of bursa-dependent lymphocyte
01/09/2001US6172218 Oligonucleotide tags for sorting and identification
01/09/2001US6172217 Method of synthesizing phosphorothioate oligonucleotides
01/09/2001US6172215 Nucleotide sequences which hybridize preferentially to microorganismal nucleotide sequences; screening for preferential microorganisms which cause gastrointestinal disorders
01/09/2001US6172214 Oligonucleotide tags for sorting and identification
01/09/2001US6172209 Aminooxy-modified oligonucleotides and methods for making same