Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
04/2001
04/24/2001US6222030 Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
04/24/2001US6222025 Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefrom
04/24/2001US6221850 For detecting and modulating levels of jun n-terminal kinases (jnk proteins), enzymes which are encoded by jnk genes.
04/24/2001US6221658 Nucleotide sequence; for decreasing intracellular levels of diacylglycerol and increasing intracellular levels of phosphatidic acid in a eukaryotic cell
04/24/2001US6221636 Method for producing L-lysine
04/24/2001US6221606 Energy transfer dye comprising a donor dye which absorbs ight and emits exitation energy, an acceptor dye the absorbs the excitation energy and fluoresces in response, and a linker linking the two dyes, at least one is a dibenzorhodamine dye
04/24/2001US6221604 Electron-deficient nitrogen heterocycle-substituted fluorescein dyes
04/24/2001US6221589 Methods and compositions for modulating melting temperatures of nucleic acids
04/24/2001US6221583 Use of nucleic acids containing electron transfer moieties to be used as nucleic acid probes; probe nucleic acid is covalently attached to an electrode via a conductive oligomer
04/24/2001CA2147618C Probe for diagnosing of infectious diseases
04/24/2001CA1341216C Human .alpha.-1-antitrypsin derivatives, and a production process
04/19/2001WO2001027323A1 Method of screening for susceptibility to drug-induced cardiac arrhythmia
04/19/2001WO2001027126A1 Process for the preparation of phosphorothioate triesters and oligonucleotides
04/19/2001WO2001019846A8 Transgenically produced fusion proteins
04/19/2001WO2000029444A9 Generation of antibodies using polynucleotide vaccination in avian species
04/19/2001CA2386867A1 Process for the preparation of phosphorothioate triesters and oligonucleotides
04/18/2001EP1092770A2 Human cancer antigen of tyrosinase-related protein 1 and 2 and genes encoding same
04/18/2001EP1092020A1 A nucleic acid encoding a retinoblastoma binding protein (rbp-7) and polymorphic markers associated with said nucleic acid
04/18/2001EP1091972A1 Reusable solid support for oligonucleotide synthesis
04/18/2001CN1291650A Human hepatome derivative growth factor coding sequence, polypeptide coded with it and its preparing process
04/17/2001US6218531 Method of isolating RNA
04/17/2001US6218530 Particularly detection of nucleic acid and nucleic acid hybridization using photocleavable agents, including photocleavable aminotag phosphoramidite
04/17/2001US6218529 Nucleotide sequences; for the detection and treatment of tumors
04/17/2001US6218175 Nano-devices using block-copolymers
04/17/2001US6218153 Sensitive detection of mutant dna in sample by amplifying using polymerase chain reaction, hybridizing amplified sample to form homo- and heteroduplexes, separating into fractions using denaturing matched ion polynucleotide chromatography
04/17/2001US6218146 MTS2 gene
04/17/2001US6218141 Assembling expression vector using defined nucleotide sequence coding for protein, transforming host cell, then expressing, isolating, and purifying protein
04/17/2001US6218124 Method for detecting oligonucleotides using UV light source
04/17/2001US6218122 Measuring abundances of cell components for a diagnostic profile, measuring abundances of cell components in analogous subjects for response profiles, and determining interpolated response profiles which best fit diagnostic profile
04/17/2001US6218111 Reagent which is an analyte moiety linked to a tag of at least two reporter groups used for detection by mass spectrometry; the reporter groups identify analyte residue and its position in analyte moiety; screening of libraries
04/17/2001US6218108 Nucleoside analogs with polycyclic aromatic groups attached, methods of synthesis and uses therefor
04/17/2001US6218104 Method of detection of carcinogenic human papillomavirus
04/17/2001US6217860 Supplying adenoviral vector into tumor
04/17/2001CA2207507C Detection of nucleic acids using g-quartets
04/17/2001CA2205892C Mutant prenyl diphosphate synthase
04/17/2001CA2164941C Salmonella identification by the polymerase chain reaction
04/17/2001CA2074135C Process for immobilizing a nucleic acid fragment by passive fixation on a solid support; solid support thus obtained and use thereof
04/17/2001CA2071483C Oligonucleotide analogs with novel linkages
04/12/2001WO2001025405A1 C-myc antisense-treated hematopoietic stem cell composition and method
04/12/2001WO2001025249A1 Compositions and methods for identifying polypeptides and nucleic acid molecules
04/12/2001WO2000049031A3 Method for isolating nucleic acids
04/12/2001WO2000012123A3 Method and measuring device for determining a plurality of analytes in a sample
04/12/2001WO1999051735A3 Mapkap kinase 2-inhibitors and the use thereof in anti-inflammatory therapy
04/12/2001CA2386192A1 C-myc antisense-treated hematopoietic stem cell composition and method
04/11/2001EP1090294A1 Methods for determining presence of cancer in a sample by determining expression of an ssx gene, peptides derived from said ssx gene and ny-eso-1 gene, and uses thereof
04/11/2001EP1090137A1 Production of polymers from nucleotidic and/or non-nucleotidic elements using enzymatic methods
04/11/2001EP1090073A1 Xanthene dyes and their application as luminescence quenching compounds
04/11/2001EP1090025A1 Antisense modulation of tnfr1 expression
04/11/2001EP1021176A4 Cobalt schiff base compounds
04/11/2001EP0710285B1 Analogues of an anti-thrombin polypeptide and process for their preparation
04/11/2001EP0517829B1 Improved chimeric toxins
04/10/2001US6214987 Mixture of a template-independent enzyme and a 3' blocked nucleotide 5'-triphosphate; efficient synthesis of oligo- and polynucleotides
04/10/2001US6214986 Antisense modulation of bcl-x expression
04/10/2001US6214981 Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof
04/10/2001US6214979 Homogeneous assay system
04/10/2001US6214974 Internalizable cell binding component having biotin binding element conjugated to biotinylated nucleic acids or cytotoxic moieties such as gelonin, ricin, saporin, abrin, diptheria toxin and the like; gene therapy; drug delivery of toxins
04/10/2001US6214973 Antibody light chain having variable region of defined amino acid sequence and human constant region; antitumor agents; anticarcinogenic agents; diagnosis
04/10/2001US6214806 Use of nucleic acids containing unmethylated CPC dinucleotide in the treatment of LPS-associated disorders
04/10/2001US6214805 Genes, gene signals, genomes rna strands and respiratory syncytial virus with promoters
04/10/2001US6214584 Nucleotide sequence which encodes polypeptide associated with immunocompetence; for use in the treatment and prevent of tumors, viral diseases, bacterial infections and autoimmune diseases
04/10/2001US6214551 Oligonucleoside linkages containing adjacent nitrogen atoms
04/10/2001US6214545 Polymorphism analysis by nucleic acid structure probing
04/10/2001US6214543 DNA molecule encoding for cellular uptake of Mycobacterium tuberculosis and uses thereof
04/10/2001CA2163151C Humanized and chimeric monoclonal antibodies that recognized epidermal growth factor receptor (egf-r). use diagnostic and therapeutic
04/05/2001WO2001023613A1 Human rnase h and oligonucleotide compositions thereof
04/05/2001WO2001023599A1 Streptococcus pneumoniae ykqc
04/05/2001WO2001023557A1 Novel polypeptides and genes encoding the same
04/05/2001WO2001023410A2 Drug target isogenes: polymorphisms in the interleukin 13 gene
04/05/2001WO2001023082A2 Biomolecular attachment sites on microelectronic arrays
04/05/2001WO2001022970A1 Therapy with 2-5a and interferon
04/05/2001US20010000149 Solid medium and process for the storage and rapid purification of nucleic acid
04/05/2001DE19945398A1 Elektrochemische Detektion von sequenzspezifischen Nukleinsäure-Oligomer-Hybridisierungsereignissen Electrochemical detection of sequence-specific nucleic acid oligomer hybridization events
04/05/2001CA2811455A1 Highly conserved genes and their use to generate species-specific, genus-specific, family-specific, group-specific and universal nucleic acid probes and amplification primers to rapidly detect and identify algal, archaeal, bacterial, fungal and parasitical microorganisms from clinical specimens for diagnosis
04/05/2001CA2388025A1 Therapy with 2-5a and interferon
04/05/2001CA2386622A1 Biomolecular attachment sites on microelectronic arrays
04/04/2001EP1088585A2 Method for automated chemical synthesis
04/04/2001EP1088105A1 Detection of non-viral organisms with srp rna
04/04/2001EP1088095A1 Novel molecules of the t110-related protein family and uses thereof
04/04/2001EP1088064A1 Rapid and simple process for isolation of circular nucleic acids
04/04/2001EP1088035A1 Efficient activated cyanine dyes
04/04/2001EP1087983A1 Method for marking a ribonucleic acid and resulting marked rna fragments
04/04/2001EP1087777A2 Therapeutic dinucleotide and derivatives
04/04/2001EP0983291A4 Carbamate-derivatized nucleosides and oligonucleosides
04/04/2001EP0658164B1 Chromatographic purification and separation process for mixtures of nucleic acids
04/04/2001CN1290175A Live vaccine for human immunodeficiency virus
04/04/2001CN1289854A Human proteasome subunit protein and its coding sequence
04/04/2001CN1289853A Human micronuclear ribonucleoprotein isomer and its coding sequence
04/04/2001CN1289852A Human nif gene homogenous protein and its coding sequence
04/04/2001CN1289851A Human micronuclear ribomucleoprotein specific 40KD protein isomer and its coding sequence
04/04/2001CN1289850A Human heat shock protein and its coding sequence
04/04/2001CN1289849A Human protein isomer induced by tumor nectosis factor and its coding sequence
04/04/2001CN1289848A Human interleukin enhancer binding factor protein isomer and its coding sequency
04/04/2001CN1289847A Human Heteronuclear ribonucleoprotein isomer and its coding sequence
04/04/2001CN1289846A Human precursor protein of transition receptor potential site and its coding sequence
04/04/2001CN1289845A Human protein isomor of transition receptor potentia site and its coding sequence
04/03/2001US6211356 Metallocene-phosphoramidite conjugates, process for their preparation and their use
04/03/2001US6211354 Optically active DNA probe having phosphonic diester linkage
04/03/2001US6211351 For introduction of genetic changes in eukaryotic cells
04/03/2001US6211350 Synthesis of oligonucleotides
04/03/2001US6211349 Protonated/acidified nucleic acids and methods of use