Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
07/2001
07/18/2001EP0819134B1 Covalently cross-linked oligonucleotides, method for preparing same, and synthon used therein
07/18/2001EP0660844B1 Isolated nucleotide sequences for identifying neisseria gonorrhoeae
07/18/2001CN1303926A Novel polypeptide-NADH-cytochrome B5 reductase 33 and polynucleotide coding said polypeptide
07/18/2001CN1303863A Novel polypeptide-human transcriptional elongation factor IIS51 and polynucleotide for coding this polypeptide
07/18/2001CN1303861A Novel retinoblastoma protein binding protein, its preparation and application
07/18/2001CN1068585C Cationic lipids for gene therapy
07/17/2001US6262252 Attaching label to nucleic acid with reagent (nitrogen mustard, sulfur mustard, and aziridines), forming covalent bond in not more than one hour
07/17/2001US6262251 Product anchored sequencial synthesis (pass); an anchor group attached to the 5' end of the growing oligonucleotide product allows the coupled product to be separated from unreacted starting materials
07/17/2001US6262250 Prenatal diagnosis of familial dysautonomia, the riley-day syndrome, via nucleic acid primers
07/17/2001US6262241 Antisense compounds which cleave phosphorodiester bonds and improve pharmacodynamic and pharmacokinetic properties of oligonucleotides, useful in diagnosing diseases
07/17/2001US6262216 Used to form a functionalized coating on substrate; array of nucleic acids may be covalently attached to substrate to make high density arrays to nucleic acids immobilized on substrate which may be used in high volume nucleic acid hybridization
07/17/2001US6262036 Method for inhibiting RNA translation using chimeric oligonucleoside compounds
07/17/2001US6262016 Transferrin receptor genes
07/17/2001US6261821 Amino acid sequence of protease-sensitive peptide; transgenic plants with disease resistance; biological pest control
07/17/2001US6261804 Selection of proteins using RNA-protein fusions
07/17/2001US6261787 Bifunctional molecules for delivery of therapeutics
07/17/2001US6261785 Amplification and detection of Bordetella pertussis
07/17/2001US6261784 Detecting targets by noncompetitive hybridization of detector oligonucleotide strands to targets by fluorescence quenching; oligonucleotides are displaced increasing distance between donor and acceptor dyes causing changes in fluorescence
07/17/2001US6261783 Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
07/17/2001US6261779 A nonradioactive detection kit using functionalized nanocrystals having a plurality of polynucleotide strands extending outward; a probe detects a target molecule by binding and generating an amplified detectable signal
07/17/2001US6261776 Nucleic acid arrays
07/17/2001US6261775 Detection of chromosome copy number changes to distinguish melanocytic nevi from malignant melanoma
07/17/2001US6261774 Truncation selex method
07/17/2001US6261497 Polytetrafluoroethylene resin chromatography membrane, heating, calendering and sintering
07/17/2001CA2151141C Mammalian receptors for interleukin-10 (il-10)
07/17/2001CA2034197C Conjugates of biologically stable polymers and polynucleotides for treating systemic lupus erythematosus
07/12/2001WO2001049864A1 Novel human proteases and polynucleotides encoding the same
07/12/2001WO2001049844A1 Compositions and methods for gene silencing
07/12/2001WO2001049790A2 Mobility-modifying cyanine dyes
07/12/2001WO2001049701A1 Process for the preparation of oligomeric compounds
07/12/2001WO2001049687A2 Cyclohexene nucleic acids
07/12/2001WO1999052541A3 Artery- and vein-specific proteins and uses therefor
07/12/2001US20010007905 Nucleic acids labelled with extended rhodamine dyes
07/12/2001US20010007902 An oligonucleotide complementary to a region of the ribonucleotide component of telomerase attached to an activator of ribonuclease L (activator-antisense complex) which cleaves ribonuclotide portion of telomerase enzyme
07/12/2001US20010007767 Genetic engineering
07/12/2001US20010007751 Labeled protein and its producing method, labeling compound to be used in the method, and method for analyzing function of genes
07/12/2001US20010007746 Immobilization
07/12/2001US20010007743 Method for screening compounds which interact with the l-enantiomer of a target rna
07/12/2001CA2402360A1 Novel human proteases and polynucleotides encoding the same
07/12/2001CA2396067A1 Mobility-modifying cyanine dyes
07/11/2001EP1114827A1 Novel nucleic acid base pair
07/11/2001EP1114059A1 Regulation of immune responses by attractin
07/11/2001EP1027121A4 Improved liquid chromatographic media for polynucleotide separation
07/11/2001EP1017466A4 Polynucleotide separations on nonporous polymer beads
07/11/2001EP0731808B1 Nucleosides and oligonucleotides containing boron clusters
07/11/2001CN1303436A Compositions and methods for sensitizing and inhibiting growth of human tumor cells
07/11/2001CN1303300A Isolated peptides corresponding to amino acid sequences of NY-ESO-1, wherein bind to MHC class I and MHC class II molecules, and uses thereof
07/11/2001CN1303298A Gene therapy approaches to supply apolipoprotein A-1 agonists and their use to treat dyslipidemic disorders
07/11/2001CN1302814A Polypeptide-human S18 ribosomal protein 18 and polynucleotide for coding it
07/11/2001CN1302813A Polypeptide-zinc finger protein 42 and polynucleotide for coding it
07/11/2001CN1302810A Method of extracting DNA from spermatophore of fish
07/10/2001US6258790 Antisense modulation of integrin α4 expression
07/10/2001US6258593 Device for hybridization assays; has substrate with surface functionalized with mixture of silane compounds which bind oligonucleotide probes to surface
07/10/2001US6258581 Amino acid and nucleotide sequences; recombinant culture production; diagnosis of atopic dermatitis
07/10/2001US6258569 Amplifying using polymerase with 5' to 3' nuclease activity, a primer, and an oligonucleotide probe with fluorescent reporter and quencher attached at opposite ends; digestion of probe by polymerase increases signal
07/10/2001US6258545 Performing polymerase chain reaction, hybridizing amplified target sequence to single-stranded nucleic acid covalently attached to electrode, detecting electron transfer between moiety on hybridization complex and electrode as indicator
07/10/2001CA2060666C Antigenic epitopes present on membrane-bound but not secreted iga
07/05/2001WO2001048480A1 METHODS FOR ISOLATING AND CHARACTERIZING ENDOGENOUS mRNA-PROTEIN (mRNP) COMPLEXES
07/05/2001WO2001048247A2 METHOD FOR GENERATION OF LONGER cDNA FRAGMENTS FROM SAGE TAGS FOR GENE IDENTIFICATION
07/05/2001WO2001048241A1 Classification and typing of prokaryotes using hyperpolymorphic simple sequence repeats
07/05/2001WO2001048190A2 Therapeutic uses of lna-modified oligonucleotides
07/05/2001WO2001047943A1 Antisense modulation of akt-3 expression
07/05/2001WO2001047627A1 Method and device for the mask-free production of biopolymers by means of a light diode array
07/05/2001WO2000061621A3 Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
07/05/2001US20010007025 Antisense modulation of bcl-x expression
07/05/2001US20010007024 Providing mixture of linear strands of nucleic acids and excess labeled dideoxy nucleotide bases, adding terminal transferase which binds labeled base to at least one end of strand, adding support that binds to base at end of strand
07/05/2001US20010006954 Synthetic DNA comprising a radiation responsive enhancer-promoter operatively linked to a polypeptide encoding region linked to a transcription terminating region; regulating gene expression and inhibiting tumor growth
07/05/2001US20010006945 Hyperstructure-forming carriers
07/05/2001US20010006816 Novel property effecting and/or property exhibiting compositions for therapeutic and diagnostic uses
07/05/2001US20010006815 Novel property effecting and/or property exhibiting compositions for therapeutic and diagnostic uses
07/05/2001US20010006814 Chemical modification
07/05/2001US20010006801 Active ribozyme
07/05/2001US20010006784 Apolipoprotein e polymorphism and treatment of alzheimer's disease
07/05/2001DE19962803A1 Verfahren und Vorrichtung zur maskenfreien Herstellung von Biopolymeren Method and apparatus for maskless production of biopolymers
07/05/2001CA2396721A1 Method and device for the mask-free production of biopolymers by means of a light diode array
07/05/2001CA2395920A1 Method for generation of longer cdna fragments from sage tags for gene identification
07/05/2001CA2395320A1 Therapeutic uses of lna-modified oligonucleotides
07/04/2001EP1113082A2 Amplification capture assay
07/04/2001EP1113021A2 Polyamide-oligonucleotide derivatives, their production and use
07/04/2001EP1113020A2 Nucleosides and oligonucleotides containing boron clusters
07/04/2001EP1112377A1 Nucleic acid-coupled colorimetric analyte detectors
07/04/2001EP1112366A1 Polynucleotides and polypeptides basb033 from neisseria meningitidis and their uses
07/04/2001EP1112281A1 Pteridine nucleotide analogs
07/04/2001EP1112279A1 Methods for the preparation of conjugated oligomers
07/04/2001EP1060264A4 Dideoxy dye terminators
07/04/2001CN1301765A New polypeptide-human kazal type inhibitory factor 35 and polynucleotide coding such polypeptide
07/04/2001CN1301764A New polypeptide-human zinc-finger protein 25 and polynucleotide coding such polypeptide
07/04/2001CN1301761A New human chemotaxis factor macrophage inflammatory protein, its coding sequence and use
07/04/2001CN1301760A New polypeptide-human cytochrome composing protein 11 and polynucleotide coding such polypeptide
07/04/2001CN1301758A New polypeptide-human transport protein 9 and polynucleotide coding such polypeptide
07/04/2001CN1301754A New polypeptide-P53 tumor antigen protein 13 and polynucleotide coding such polypeptide
07/04/2001CN1301751A New polypeptide-cytochrome b559 10 and polynucleotide coding such polypeptide
07/04/2001CN1301750A New polypeptide-ribosome S11 protein 9 and polynucleotide coding such polypeptide
07/04/2001CN1301742A New polypeptide-acid phosphatase family protein 7 and polynucleotide coding such polypeptide
07/04/2001CN1301715A New polypeptide-I-type aminoacy/tRNA synthetase 10 and polynucleotide coding such polypeptide
07/04/2001CN1301714A New polypeptide-interferon protein 14 and polynucleotide coding such polypeptide
07/04/2001CN1301711A New polypeptide-staphylocoagulase repeated peptide 14 and polynucleotide coding such polypeptide
07/04/2001CN1301705A Novel polypeptide-cytochrome b 5-13 and polynucleotide coding such polypeptide
07/03/2001US6255477 Made by forming a sol form alcohol and metal alkoxides, contacting with magnetic cores, spray drying to enclose cores in gel layer, heating to form a coating of nonporous glass and recovering individually free magnetic glass particles
07/03/2001US6255476 Reacting a labelled solid support of given formula to remove an acid cleavable protecting group, adding a 5'-phosphoramidite, 3'-protected nucleoside and an activator to from a bond