Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/2001
08/01/2001EP1119579A1 Antisense modulation of bcl-x expression
08/01/2001EP1119578A1 Improved process for oligonucleotide synthesis
08/01/2001EP0889959B1 Partial intron sequence of von hippel-lindau (vhl) disease gene and its use in diagnosis of disease
08/01/2001EP0763133B1 Method for detecting a target nucleic acid
08/01/2001EP0740703B1 Diagnosis and treatment of infections due to streptococci and enterococci
08/01/2001CN1306542A Moraxella catharralis proteins
08/01/2001CN1306436A Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
08/01/2001CN1306006A BioHNTP13 molecular weight of 13 KDa and its coding sequence
08/01/2001CN1306004A Application of bee larva in preparing nucleic acid
07/2001
07/31/2001US6268490 Bicyclonucleoside and oligonucleotide analogues
07/31/2001US6268221 Drug screening for compound which binds to receptor by transforming host cell with recombinant expression contruct encoding the receptor, expressing in culture, and analyzing cells to determine binding
07/31/2001US6268210 Two substrates, each having spatially addressable array of immobilized biological compounds, and spacer between substrates to form chambers; assay solution contacts at least one compound from each array; use; storage; transportation
07/31/2001US6268180 A nucleic acid encoding a polypeptide; production of biologically active interleukin
07/31/2001US6268171 Recombinant PilC proteins, methods for producing them and their use
07/31/2001US6268152 Kit for the detection of preferential nucleotide sequences; for use in the diagnosis and detection of genetic disorders
07/31/2001US6268151 Antisense modulation of macrophage migration inhibitory factor expression
07/31/2001US6268150 Nucleic acid mediated electron transfer
07/31/2001US6268149 Nucleic acid mediated electron transfer
07/31/2001US6268138 Retroviral vector capable of transducing the aldehyde dehydrogenase-1 gene and making cells resistant to the chemotherapeutic agent cyclophosphamide and its derivatives and analogs
07/31/2001US6268137 Phosphorothioate or phosphorodithioate linkages; cancer diagnosis
07/31/2001US6268132 Amplification, sequencing, replication, transcripition, enzymatic digestion, hybridization, medical diagnosis
07/31/2001US6268129 Method of nucleic acid analysis
07/31/2001US6267965 Vectors for insertion and expression of foreign genes for use as safe immunization vehicles to elicit immune response against poxvius-ctyomegalovirus and human cytomegalovirus
07/31/2001US6267859 DNA sample preparation and electrophoresis analysis apparatus
07/31/2001CA2121144C Oligonucleotides having chiral phosphorus linkages
07/31/2001CA2069428C A mammalian cytokine, il-11
07/28/2001CA2331674A1 Isolated polynucleotides and polypeptides relating to loci underlying resistance to soybean cyst nematode and soybean sudden death syndrome and methods employing same
07/26/2001WO2001053538A2 Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease
07/26/2001WO2001053533A2 Method for cloning polyketide synthase genes
07/26/2001WO2001053523A1 Method for synthesising and immobilising nucleic acids on a silanized solid support
07/26/2001WO2001053352A2 Sperm specific proteins
07/26/2001WO2001053317A1 Antisense modulation of macrophage migration inhibitory factor expression
07/26/2001WO2001053315A1 Antisense modulation of ara70 expression
07/26/2001WO2001053314A1 Antisense modulation of daxx expression
07/26/2001WO2001053307A1 2'-arabino-fluorooligonucleotide n3'→p5'phosphoramidates: their synthesis and use
07/26/2001WO2001052865A1 Antisense modulation of glycogen synthase kinase 3 alpha expression
07/26/2001WO2001052864A1 Antisense modulation of cot oncogene expression
07/26/2001WO2001052862A1 Antisense modulation of glycogen synthase kinase 3 beta expression
07/26/2001WO2001016152A3 Method for anchoring oligonucleotides to a substrate
07/26/2001WO2001000876A9 Nanoparticles having oligonucleotides attached thereto and uses therefor
07/26/2001WO2000067894A3 Methods of software driven flow sorting for reiterative synthesis cycles
07/26/2001WO2000056342A3 Use of stabilised oligonucleotides for preparing a medicine with antitumour activity
07/26/2001US20010009763 Array of a plurality of particles having probes, respectively, fixed thereon, said probes being capable of binding to different target substances to be examined, respectively
07/26/2001US20010009760 Reducing background signals in nucleic acid hybridization assays by using an oligonucleotide labelled with a quenchable dipyrrolometheneboron difluoride dye
07/26/2001CA2398243A1 Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease
07/26/2001CA2397838A1 Sperm specific proteins
07/26/2001CA2397205A1 Antisense modulation of macrophage migration inhibitory factor expression
07/26/2001CA2397202A1 Antisense modulation of glycogen synthase kinase 3 alpha expression
07/26/2001CA2396697A1 Antisense modulation of glycogen synthase kinase 3 beta expression
07/26/2001CA2395749A1 Methods and materials relating to prothrombinase-like polypeptides and polynucleotides
07/26/2001CA2395736A1 Novel nucleic acids and polypeptides
07/26/2001CA2395731A1 Methods and materials relating to g protein-coupled receptor-like polypeptides and polynucleotides
07/25/2001EP1118678A1 Method for diagnosing polymorphisms in the human PDH E1 beta gene
07/25/2001EP1117996A2 Method and device for producing and/or analyzing biochemical reaction supporting materials
07/25/2001EP1117838A1 A method for analyzing polynucleotides
07/25/2001EP1117808A2 Transformation system in the field of filamentous fungal hosts: in chrysosporium
07/25/2001EP1117768A1 Dnazymes and methods for treating restenosis
07/25/2001EP1117678A1 Solid phase synthesis, whereby the solid phase consists of two different substrates
07/25/2001EP1117672A1 Antisense modulation of survivin expression
07/25/2001EP1117478A2 Support for a method for determining an analyte and a method for producing the support
07/25/2001EP1117439A1 Methods for identification, diagnosis, and treatment of breast cancer
07/25/2001CN1305010A Determination primer for polymerase chain reaction of sailonggu as Chinese-medicinal material and its determination method
07/25/2001CN1304998A New nucleotide sequence of encode zwal gene
07/24/2001US6265635 DNA sequences coding for enzymes capable of facilitating the synthesis of linear α-1,4 glucans in plants, fungi and microorganisms
07/24/2001US6265568 Nucleotide sequences for use in the diagnosis and detection of microorganism infection
07/24/2001US6265567 Isolated FrpB nucleic acid molecule
07/24/2001US6265563 Nucleotide sequences probes for use as diagnostic tools and drug screening
07/24/2001US6265559 Peptide nucleic acid synthons which have protecting groups which are orthogonal; allows removal of protecting groups under mild conditions; for pna-dna chimeras
07/24/2001US6265558 Compound of linked nucleosides having thiol group attatched at 5-pyrimidine or 2-, 6-, or 8-purine positions; attachment reporter molecules, reporter enzymes, steroids, lipophilic molecules, peptides, proteins and other groups
07/24/2001US6265543 Polypeptide for the treatment of eye disorders, tumors, cancer, psoriasis, trauma, psychological, burns and ulcers
07/24/2001US6265390 Methods for expressing nucleic acid sequences using nucleic acid constructs comprising hypoxia response elements
07/24/2001US6265388 Antisense inhibition of angiogenin expression
07/24/2001US6265218 Introducing promoter and heterologous dna encoding a product into plasmid containing antibiotic resistance selection marker, amplifying, using restriction enzymes to form two fragments, cyclizing to form separate plasmids
07/24/2001US6265216 Antisense modulation of cot oncogene expression
07/24/2001US6265189 Expressing polypeptide in cell culture; insert gene into viral expression vector, transform cells, recover preferential polypeptide
07/24/2001US6265172 Detecting mutations in regulatory sequences of enzymatic polypeptides; obtain nucleotide sequences, incubate with restriction enzymes, monitor pattern, detect restriction fragment length polymorphisms
07/24/2001US6265168 Apparatus and method for separating and purifying polynucleotides
07/24/2001US6265156 Detecting nucleotide sequence hybrids in sample tissue; mix cells and nucleotide probes, detect position of signal in preferential tissues
07/24/2001US6265155 Metallic solid supports modified with nucleic acids
07/24/2001US6265149 Screening sample for preferential immunological complexes; incubate sample with antigen, incubate sample with control, monitor complexes formed, count complexes in samples, more complexes in antigen sample indicates presence of retrovirus
07/24/2001CA2037291C Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
07/19/2001WO2001051689A1 Biomolecules having multiple attachment moieties for binding to a substrate surface
07/19/2001WO2001051667A2 Informative nucleic acid arrays and methods for making same
07/19/2001WO2001051665A2 Nanoparticles having oligonucleotides attached thereto and uses therefor
07/19/2001WO2001051661A2 A universal nucleic acid amplification system for nucleic acids in a sample
07/19/2001WO2001051620A2 Pullulanase variants and methods for preparing such variants with predetermined properties
07/19/2001WO2001051532A1 Copolymers derived from vinyl dicyanoimidazoles and other monomers
07/19/2001WO2001051502A1 Improved synthesis of sulfurized oligonucleotides
07/19/2001WO2001051003A2 Use of lipid conjugates in the treatment of disease
07/19/2001US20010008936 Oligonucleotides having chiral phosphorus linkages
07/19/2001US20010008765 Solid carrier with vinylsulfonyl groups
07/19/2001US20010008615 Dispensing tool; substrate with wells; vesicle elements or pins
07/19/2001CA2397391A1 Informative nucleic arrays and methods for making same
07/19/2001CA2397091A1 Biomolecules having multiple attachment moieties for binding to a substrate surface
07/19/2001CA2395765A1 Improved synthesis of sulfurized oligonucleotides
07/18/2001EP1115887A1 Parallel selex
07/18/2001EP1115866A1 Cystine knot growth factor mutants
07/18/2001EP1115848A1 Dna polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides
07/18/2001EP1115424A1 Method and measuring device for determining a plurality of analytes in a sample
07/18/2001EP0846170B1 Modified protein kinase a-specific oligonucleotides and methods of their use