Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/2001
08/28/2001CA2054706C Very large scale immobilized polymer synthesis
08/23/2001WO2001061044A1 Data analysis and display system for ligation-based dna sequencing
08/23/2001WO2001060996A1 Method of controlling telomere length
08/23/2001WO2001060856A2 Vmglom gene and its mutations causing disorders with a vascular component
08/23/2001WO2001060769A1 Segment synthesis
08/23/2001WO2001060316A2 Method for the positioning of macromolecules and particles
08/23/2001WO2001023082A3 Biomolecular attachment sites on microelectronic arrays
08/23/2001US20010016652 Providing a purine or pyrimidine base containing nucleoside with acid labile hydroxyl protecting group and a base labile hydroxy protecting group substitutions, deblocking hydroxy group, treating with phosphonate compound, condensing agent
08/23/2001US20010016575 Antisense modulation of human MDM2 expression
08/23/2001US20010016352 Oligonucleotides; detection cancer
08/23/2001US20010016340 Antihemophilia agent
08/23/2001US20010016200 Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
08/23/2001CA2400263A1 Method of controlling telomere length
08/23/2001CA2388738A1 Data analysis and display system for ligation-based dna sequencing
08/22/2001EP1126025A2 Oligonucleotide modulation of protein kinase C
08/22/2001EP1125945A1 Reversible photocoupling nucleic acid and phosphoroamidite
08/22/2001EP1125905A1 Segment synthesis
08/22/2001EP1124952A2 Therapeutic antiangiogenic endostatin compositions
08/22/2001EP1124950A2 p53 ANTISENSE AGENT AND METHOD
08/22/2001EP1124838A2 Nucleic acid labeling compounds
08/22/2001EP1124568A1 Polyspecific binding molecules and uses thereof
08/22/2001EP0931165A4 Measurement of gene expression profiles in toxicity determination
08/22/2001EP0764204B1 HUMAN OXALYL-CoA DECARBOXYLASE
08/22/2001EP0673255B1 Monoclonal antibody which specifically binds to tumor vascular endothelium and uses thereof
08/22/2001CN1309721A Heteroduplex mutational vectors and use thereof in bacteria
08/22/2001CN1309182A Cholesterol regulatory factor binding protein and its coding sequence
08/22/2001CN1309135A Novel human protein able to suppress cancer cell growth and its coding sequence
08/22/2001CN1309134A Novel human Kruppel homologous protein and its coding sequence
08/21/2001US6277982 Alkylation of alcohols, amines, thiols and their derivatives by cyclic sulfate intermediates
08/21/2001US6277980 Mixed backbone oligonucleotide analog having nucleotide sequence complementary to e6/e7 genes; has phosphorothioate bonds and at least one other phosphorus linking group or modification; viricides
08/21/2001US6277967 Having alternating phosphodiester and phosphorothioate linkages; nuclease resistant with reduced side effects; diagnosis; antisense agents
08/21/2001US6277962 Receptor on the surface of activated t-cells: act-4
08/21/2001US6277632 Highly efficient, rapid linkage of nucleic acid components in a predetermined order to produce multicomponent construct (each component having single stranded terminal sequence that allows for specific annealing)
08/21/2001US6277607 Amplification using primers that when not bound to target, form a hairpin structure in which the 3' terminal region of the primer is hybridized to the 5' terminal region of the primer to form a double-stranded stem, single stranded loop
08/21/2001US6277604 Accumulating nucleotide sequences; incubate nucleotide sequences with support, oligonucleotides primers and polymerase, recover amplification product
08/21/2001US6277603 Peptide nucleic acid (pna); the dna portion is composed of subunits of at least one 2'-deoxynucleotides; increased nuclease resistance; activate rnase h enzyme, use for in vitro modification of rna
08/21/2001US6277590 Genetically engineered aggregates for generating preferential heterologous proteins
08/21/2001US6277577 Hybridization probes derived from the spacer region between the 16s and 23s rRNA genes for the detection of non-viral microorganisms
08/21/2001US6277576 Nucleic acid mediated electron transfer
08/21/2001US6277571 Degenerate oligonucleotides designed to bind specific homologous regions of matrix metalloproteinases family members, generating cdnas and dna segments from tissues; screening for brain/tumor specific enzymes
08/21/2001US6277570 Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
08/21/2001US6277334 Chemical synthesis apparatus employing a droplet generator
08/21/2001CA2174315C Oligonucleotide modulation of multidrug resistance-associated protein
08/16/2001WO2001059134A1 Human proteases and polynucleotides encoding the same
08/16/2001WO2001059100A2 Inhibitor of hepatocyte growth factor activator for use in modulation of angiogenesis and cardiovascularization
08/16/2001WO2001059093A2 FULL-LENGTH INFECTIOUS cDNA CLONES OF TICK BORNE FLAVIVIRUS
08/16/2001WO2001059079A1 UDP-GALACTOSE: β-D-GALACTOSE-R 4-α-D-GALACTOSYLTRANSFERASE, α4GAL-T1
08/16/2001WO2001059077A1 Porcine reproductive and respiratory syndrome virus and methods of use
08/16/2001WO2001012853A8 Method for identification of the indicators of contamination in samples
08/16/2001WO2001009385A3 Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids
08/16/2001WO2000071732A3 Nucleotide sequence for increasing the defense reaction of a plant against infection by a pathogen
08/16/2001US20010014735 Hybrid stabilization
08/16/2001US20010014650 Adsorption, desorption of targeted nucleic acids
08/16/2001US20010014453 Such as N,N-bis(2-trimethoxysilylpropyl)ethanolamine; for silanation of surfaces such as glass and subsequent immobilization of nucleic acids and polypeptides
08/16/2001US20010014449 The stabilizer, reporter, and target amplicons are hybridized using electronic assistance of the microchip system so that base-stacking energies are used in discerning among other indicators such as wildtype or polymorphism sequence
08/16/2001US20010014448 Reagent for covalent attachment of nucleic acids onto the surface of the substrate, comprising a polymer backbone having pendant thermochemically reactive groups; making activated slides for use in microarrays
08/16/2001EP1123976A1 New human hepatoma-derived growth factor encoding sequence and polypeptide encoded by such dna sequence and producing method thereof
08/16/2001EP1123414A1 Antisense modulation of integrin alpha 4 expression
08/16/2001EP1123386A1 Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
08/16/2001EP1123305A1 Dna-templated combinatorial library chemistry
08/16/2001EP0937097B1 Compositions and methods for immobilizing nucleic acids to solid supports
08/16/2001EP0891369B1 Process and device for isolating nucleic acids
08/16/2001EP0888372B1 Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates
08/16/2001EP0749444B1 Hybrid human/animal factor viii
08/16/2001EP0668932B1 Positional sequencing by hybridization
08/16/2001DE10004659A1 Verfahren und Vorrichtung zur Synthese und Analyse von trägergebundenen Arrays von Oligomeren, insbesondere von Primerpaaren für die PCR, sowie Träger mit Oligomeren Method and apparatus for the synthesis and analysis of support-bound arrays of oligomers, in particular pairs of primers for PCR, as well as carrier with oligomers
08/16/2001CA2400583A1 Porcine reproductive and respiratory syndrome virus and methods of use
08/16/2001CA2399876A1 Human proteases and polynucleotides encoding the same
08/16/2001CA2399860A1 Udp-galactose: .beta.-d-galactose-r 4-.alpha.-d-galactosyltransferase, .alpha.4gal-t1
08/15/2001CN1308130A Method of extracting nucleic and from microbe cell
08/14/2001US6274725 Providing compound having a hydroxyl group; reacting with phosphitylating reagent in the presence of a pyridinum salt in a solvent under conditions of time, temperature and pressure to yield phosphitylated compound
08/14/2001US6274724 Cyclic imidazole compounds having relatively low hydrogen content and relatively high nitrogen content and polymers and copolymers formed therefrom
08/14/2001US6274723 Dendritic nucleic acids exhibiting maximal self-assembly
08/14/2001US6274711 Proteins and mimetics which function in regulating, controlling physiology, development, and differentiation of mammalian immune cells including hemopoietic type; cytotoxic t lymphocyte activated or associated antigen (ctla)
08/14/2001US6274702 Bone stimulating factor
08/14/2001US6274562 Method of inhibiting the proliferation and causing the differentiation of cells with IGF-1 receptor antisense oligonucleotides
08/14/2001US6274351 Solid support for solid phase amplification and sequencing and method for preparing the same nucleic acid
08/14/2001US6274316 Detecting antibiotic resistant bacteria; lyse cells, incubate with probes, detect split segments of probes
08/14/2001US6274313 Oligonucleotides with cationic phosphoramidate internucleoside linkages and methods of use
08/14/2001US6274145 To generate cytolytic t cells against abnormal cells; as markers for pathological or abnormal condition in diagnosis
08/14/2001US6274134 Human cell adhesion protein AAMP-1 and uses thereof
08/14/2001US6274117 Cytokines that bind the cell surface receptor Hek
08/14/2001CA2012312C Genetic units for inhibiting the function of rna
08/09/2001WO2001057269A2 Nucleic acid detection methods using universal priming
08/09/2001WO2001057264A2 Electron-deficient nitrogen heterocycle-substituted fluorescein dyes
08/09/2001WO2001057257A2 Isolation and identification of mrnas correlating to secreted proteins
08/09/2001WO2001057249A1 Synthesis of spatially addressed molecular arrays
08/09/2001WO2001057059A1 Antisense modulation of survivin expression
08/09/2001WO2001056691A2 Method and device for the synthesis and the analysis of support-bound arrays of oligomers, especially of primer pairs for pcr, as well as oligomer-carrying supports
08/09/2001WO2001056581A1 Powdered preparation for inhalation and powder inhalant containing the same packed
08/09/2001WO2001016312A3 Nucleic acid based modulators of gene expression
08/09/2001US20010012618 Useful for enzymatic cleavage of RNA or single stranded DNA, and also as antisense oligonucleotides; improved stability and activity
08/09/2001US20010012614 Nucleotide sequence from mRNA untranslated regions encoding RNA binding proteins (RBPs) binding proteins; use in drug screening; use in modifying post-transcriptional protein expression
08/09/2001CA2398889A1 Antisense modulation of survivin expression
08/09/2001CA2398172A1 Synthesis of spatially addressed molecular arrays
08/08/2001EP1122316A1 Process for obtaining transgenic plants which have an improved capacity for the uptake of nutrients and tolerance to toxic compounds which are presents in the soil
08/08/2001EP1121471A1 Nucleic acid arrays
08/08/2001EP1121373A2 Immunostimulatory oligonucleotides with modified bases and methods of use thereof
08/08/2001EP1121371A1 Nucleotide compounds including a rigid linker
08/08/2001EP1054595A4 Methods and compounds for the genetic treatment of hyperlipidemia