Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
05/1997
05/06/1997US5627185 Acyclovir derivatives as antiviral agents
05/06/1997US5627165 Phosphorous prodrugs and therapeutic delivery systems using same
05/06/1997US5627160 L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents
05/06/1997US5627053 2'deoxy-2'-alkylnucleotide containing nucleic acid
05/02/1997EP0770621A1 2'-deoxy-2'-(substituted or unsubstituted methylidene)-4'-thionucleoside
05/02/1997EP0642525B1 Nucleosides being O-acylated with a mono-unsaturated omega-9 C18 or C20 fatty acid
05/01/1997CA2235490A1 Papyracillic acid, method for preparation and its use as synthon for bioactive substances
04/1997
04/30/1997CN1148811A Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions
04/29/1997US5625081 Fluorescent dye intermediates
04/29/1997US5625078 Processes for the production of 13-ether derivatives of milbemycins and novel intermediates therefor
04/29/1997US5625057 Process for preparing 2',3'-Dideoxy-2',3'-dehydronucleosides
04/29/1997US5625056 Inhibitors or stimulants for kinases for ligands for chromatography
04/29/1997US5625050 Modified oligonucleotides and intermediates useful in nucleic acid therapeutics
04/29/1997US5625046 Hydroxyl projecting groups for organic synthesis
04/29/1997US5624913 Reducing tumor necrosis factor
04/29/1997US5624842 Strain of Streptomyces for the production of tricyclo compounds
04/29/1997US5624802 Nucleic acid multimers and amplified nucleic acid hybridization assays using same
04/24/1997WO1997014710A1 Preparation of phosphorothioate oligomers
04/24/1997WO1997014708A1 Oligonucleotides containing thiol-substituted nucleoside derivatives and methods of use thereof
04/24/1997WO1997014706A1 Method for solution phase synthesis of oligonucleotides
04/24/1997CA2234159A1 Method for solution phase synthesis of oligonucleotides
04/23/1997EP0769017A1 Therapeutic compounds
04/23/1997EP0768883A1 Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
04/22/1997US5623081 Method for producing tetrahydrofuranyl compounds
04/22/1997US5623070 Modified nucleosides which form oligonucleotide mimics with improved nuclease resistance
04/22/1997US5623069 Phosphorylation of nucleoside in an organic phosphate solvent using phosphorus oxyhalogenide
04/22/1997US5623068 Synthesis of DNA using substituted phenylacetyl-protected nucleotides
04/22/1997US5623065 Gapped 2' modified oligonucleotides
04/22/1997US5622945 Rubyrin macrocycles
04/22/1997US5622828 Contacting mixture of nucleic acids with secretory phospholipase a2, partitioning increased affinity nucleic acids, amplifying
04/22/1997US5622824 DNA sequencing by mass spectrometry via exonuclease degradation
04/20/1997WO1998017675A1 Improved methods for h-phosphonate synthesis of mono- and oligonucleotides
04/17/1997WO1997013777A1 Novel orthosomycins from micromonospora carbonacea
04/16/1997EP0767842A1 Methods of screening for nucleoside analogs that are incorporated by hiv reverse transcriptase and cause incorrect base pairing
04/16/1997EP0767668A1 Polynucleoside chain having multiple nucleosides, the nucleosides coupled by guanidyl linkages
04/16/1997EP0767657A1 Novel method of preparation of known and novel 2'-modified nucleosides by intramolecular nucleophilic displacement
04/16/1997EP0539479B1 Heterocyclic compounds
04/16/1997CN1147815A Adenosine derivatives
04/16/1997CN1147519A Preparation of d4T from 5-methyluridine
04/16/1997CN1034575C Producing process for selective adenosine receptor agents
04/15/1997US5621087 Analgesics
04/15/1997US5621086 Tetra-o-acetylsialic acid and acetylcytidine-5'-o-amidite derivatives are condensed in presence of acid catalyst to obtain phophite, intermediate is oxidized to obtain phosphate, deprotecting the phosphate with an alkali
04/15/1997US5620963 Oligonucleotides for modulating protein kinase C having phosphorothioate linkages of high chiral purity
04/15/1997US5620874 Incubation; antihelminthic utility
04/15/1997US5620676 Biologically active ATP analogs
04/10/1997DE19537334A1 New piperidine carboxylic acid and pyrrolidine carboxylic acid derivs.
04/10/1997CA2187392A1 Antiadhesive piperidine-and pyrrolidinecarboxylic acids
04/09/1997EP0767239A2 Process for the enzymatique synthesis of nucleotide-G-desoxy-D-xylo-4-hexoses
04/09/1997EP0766692A1 Guanylic acid derivatives and their use as drugs
04/09/1997EP0766691A1 Hydroxyalkylammonium-pyrimidines or purines and nucleoside derivatives, useful as inhibitors of inflammatory cytokines
04/09/1997EP0766689A1 Novel oligosaccharide derivatives, preparation method therefor and uses thereof
04/09/1997EP0766688A1 Synthesis of oligonucleotides
04/09/1997EP0629202B1 Antiparasitic avermectin and milbemycin derivatives
04/09/1997EP0348458B1 Dna molecules stabilized by modifications of the 3'-terminal phosphodiester linkage and their use as nucleic acid probes and as therapeutic agents to block the expression of specifically targeted genes
04/08/1997US5618820 1,3-oxathiolane nucleoside analogues and methods for using same
04/08/1997US5618803 Targeted drug delivery via phosphonate derivatives
04/08/1997US5618793 Nikkomycin analogs
04/08/1997US5618704 Backbone-modified oligonucleotide analogs and preparation thereof through radical coupling
04/07/1997CA2187071A1 Process for the enzymic systhesis of nucleotide-6-deoxy-d-xylo-4-hexuloses
04/02/1997EP0765879A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests
04/02/1997EP0765665A1 Use of dideoxy nucleoside analogues in the treatment of viral infections
04/01/1997US5616702 Antitumor agents, viricides
04/01/1997US5616700 Processes for synthesizing nucleotides and modified nucleotides using N.sub.
04/01/1997US5616600 Griseolic acid compounds and their use as a phosphodiesterase inhibitor
04/01/1997US5616567 2'-Cyano pyrimidine nucleoside compounds
04/01/1997US5616566 Contacting the hiv reverse transcriptase within that cell with 2',3'-dideoxyadenosine-5'-triphosphate
03/1997
03/30/1997CA2186650A1 13-substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and others pests
03/27/1997WO1997011087A1 L-nucleoside dimer compounds and therapeutic uses
03/27/1997WO1997011083A1 Improvements in or relating to mutagenesis of nucleic acids
03/27/1997WO1997011080A1 Substituted thiol macrolactam immunomodulators
03/27/1997WO1997001344A3 Method of dynamic retardation of cell cycle kinetics to potentiate cell damage
03/27/1997CA2232506A1 Improvements in or relating to mutagenesis of nucleic acids
03/27/1997CA2206878A1 L-nucleoside dimer compounds and therapeutic uses
03/26/1997EP0662975B1 2-substituted adenosines with a-2 receptor affinity
03/26/1997EP0611373B1 Oligo-2'-deoxynucleotides and their use as drugs with an antiviral action
03/26/1997EP0543906B1 Hydroxyl-protecting groups orthogonally removable by reduction and their use in the chemical synthesis of oligonucleotides
03/26/1997EP0539493B1 Targeted drug delivery via phosphonate derivatives
03/26/1997CN1145903A D4T polymorphic form I process
03/25/1997US5614622 5-pentenoyl moiety as a nucleoside-amino protecting group, 4-pentenoyl-protected nucleotide synthons, and related oligonucleotide syntheses
03/25/1997US5614621 Process for preparing oligonucleotides using silyl-containing diamino phosphorous reagents
03/25/1997US5614617 Nuclease resistant, pyrimidine modified oligonucleotides that detect and modulate gene expression
03/25/1997US5614557 Method of controlling tumor growth rate
03/25/1997US5614504 Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
03/25/1997US5614470 13-substituted milbemycin derivatives, their preparation and their use
03/25/1997US5614362 Nucleic acid hybridization assay for hepatitis B virus DNA
03/25/1997CA1339010C Oligonucleotide polymeric support system
03/20/1997WO1997010233A1 Biocatalytic methods for synthesizing and identifying biologically active compounds
03/20/1997CA2240468A1 Biocatalytic methods for synthesizing and identifying biologically active compounds
03/19/1997EP0763051A1 3'-(4'-) nonradioactively tagged nucleosides and nucleotides with aminocarboxylic acid, peptide or carboxylic acid spacer
03/19/1997EP0763049A1 New lipid esters of nucleoside monophosphates and their use as immunosuppressive drugs
03/19/1997EP0763048A1 Post exposure prevention of hiv
03/19/1997EP0763047A2 Novel method of producing nucleosides
03/19/1997EP0763042A1 Polycyclic lactam derivatives for sensitizing multidrug-resistant cells to antitumour agents
03/19/1997EP0763041A1 Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agents
03/19/1997EP0763040A1 Carbazole derivatives as agents against multi-drug resistance
03/19/1997EP0763009A1 Photocleavable agents and conjugates for the detection and isolation of biomolecules
03/19/1997CN1145622A 06-substituted guanine derivatives, a process for their prepn. and their use
03/18/1997US5612474 Acid labile immunoconjugate intermediates
03/18/1997US5612468 Genetic engineering
03/18/1997US5612350 Autoimmune diseases and transplant tissue rejection