Patents
Patents for C07D 503 - Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (648)
06/1983
06/01/1983EP0080284A1 Derivatives of clavulanic acid, processes for their preparation and their use
05/1983
05/04/1983EP0078026A2 Antibiotic synthesis
05/03/1983US4382084 Oxapenicillins; synergistic with penicillins and cephalosporins; enzyme inhibitors; enzymes/hydrolases/
04/1983
04/13/1983EP0076369A1 Beta-lactam compounds
04/12/1983CA1144540A1 6-AMIDINOPENICILLANIC ACID DERIVATIVES INCLUDING THE RADICAL OF A .beta.-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME
02/1983
02/08/1983US4372962 Clavulanic acid derivatives their preparation and use
02/08/1983US4372946 Clavulanic acid derivatives their preparation and use
01/1983
01/18/1983US4369312 Method of producing oxo-containing azetidinone compounds
01/11/1983US4368156 Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones
01/05/1983EP0068715A1 Beta-lactam antibacterial agents, their preparation and use
01/05/1983EP0068617A1 Derivatives of clavulanic acid, a process for their preparation and their use
01/05/1983EP0068609A1 Derivatives of clavulanic acid, a process for their preparation and their use
01/04/1983US4367175 Pure potassium salt of clavulanic acid
12/1982
12/22/1982EP0067518A1 Modified beta-lactam compounds
12/14/1982CA1137479A1 Clavulanic acid derivatives, preparation and use
11/1982
11/16/1982US4359473 And b-lactamase inhibitors
10/1982
10/19/1982US4354974 Clavudienes
10/13/1982EP0062407A1 Therapeutic compounds containing beta-lactams
09/1982
09/29/1982EP0061253A2 Process for the transfer of genetic material into actinomycete cells, prepared cells and method of culturing these cells and isolating a metabolite
09/28/1982CA1132548A1 Derivatives of clavulanic acid, a process for their preparation and their use
09/15/1982EP0060120A1 Process for preparing 4-haloazetidin-2-ones
08/1982
08/31/1982US4347183 Reacting a 4-substituted azedidin-2-one with an acid halide; reacting the product with a trialkyl phosphite
08/25/1982EP0058317A1 Process for the preparation of 2-penem compounds
08/24/1982CA1130294A1 Clavulanic acid derivatives, their preparation and use
08/11/1982EP0057664A2 Clavam derivatives
08/10/1982US4343807 Beta-lactamase inhibitors, bactericides, antibiotics
08/10/1982US4343806 Benzylamino clavulanates and their production
08/03/1982US4342772 β-Lactam compounds, antibacterial compositions thereof and method of use
08/03/1982US4342749 Clavulanic acid derivatives a process for their preparation and their use in pharmaceutical compositions
06/1982
06/30/1982EP0055137A2 Method for concentrating beta-lactam antibiotic solution
06/30/1982EP0055062A1 Compounds containing beta-lactams
06/29/1982CA1126733A1 Process for the preparation of thioether derivatives of deoxyclavulanic acid
06/16/1982EP0053893A1 Derivatives of clavulanic acid, their preparation and their use
06/15/1982CA1125758A1 Clavulanic acid derivatives their preparation and use
05/1982
05/05/1982EP0050932A1 Therapeutic compounds containing beta-lactams
04/1982
04/20/1982US4325960 6-Amidinopenicillanic acid derivatives including the radical of a β-lactamase inhibitor
04/13/1982CA1121821A1 .beta.-LACTAM CONTAINING COMPOUNDS, THEIR PREPARATION AND USE
02/1982
02/24/1982EP0046349A1 Clavulanic acid derivatives, their preparation and use
02/09/1982US4314941 B-lactamase inhibitors, synergists for penicillins and cephalosporins
02/02/1982CA1117532A1 Derivatives of clavulanic acid, their preparation and use
01/1982
01/19/1982CA1116603A1 PROCESS FOR THE PREPARATION OF .beta.-LACTAM COMPOUNDS
01/13/1982EP0043546A2 7-Oxo-cephalosporins and 6-oxo-penicillins, their analogues and process for their preparation
12/1981
12/23/1981EP0042220A1 Process for the preparation of beta-lactam antibiotics
12/01/1981US4303665 Methylaminodeoxy-clavulanic acid derivatives, their production and use
11/1981
11/17/1981US4301168 Tetrahydropyridyl derivatives of clavulanic acid, a process for their preparation and their use
10/1981
10/27/1981US4297345 Deoxy- and isodeoxyclavulanic acid symergistic with penicillin and cephalosporin anditiotics
10/06/1981US4293555 6- and 6,6-Disubstituted-2-substituted-oxapen-2-em-3-carboxylic acids
09/1981
09/22/1981US4290949 Esters of 2-vinylclav-2-em-3-carboxylic acid and process for preparing same
08/1981
08/25/1981CA1107739A1 .beta.-LACTAM COMPOUNDS
08/11/1981US4283531 Hydroxyalkylation
07/1981
07/21/1981CA1105467A1 .beta.-LACTAM COMPOUNDS, PREPARATION AND USE
06/1981
06/23/1981US4275067 Fungicide and b-lactamase inhibitors
06/09/1981US4272439 6-(Substituted-hydroxymethylene penams)
06/09/1981CA1102810A1 .beta.-LACTAM ANTIBACTERIAL AGENTS
05/1981
05/26/1981US4269773 Fused oxazolidine compounds
05/06/1981EP0028083A1 Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them
04/1981
04/22/1981EP0027324A1 Derivatives of clavulanic acid, processes for their preparation and pharmaceutical compositions containing them
04/22/1981EP0027323A1 Derivatives of clavulanic acid, processes for their preparation and pharmaceutical compositions containing them
04/01/1981EP0026044A1 Amine salt of clavulanic acid, its preparation and use
03/1981
03/24/1981US4258050 Antibacterial agents
03/18/1981EP0025287A1 Clavulanic acid derivatives, their preparation, pharmaceutical compositions containing them and their preparation
03/18/1981EP0025271A1 Derivatives of clavulanic acid, their preparation and pharmaceutical compositions containing them
03/17/1981US4256638 Chemical condensation of the corresponding diene derivative with a secondary amine; hydrogenolysis to form the acid
03/17/1981CA1097654A1 Process for the preparation of ethers of clavulanic acid
03/17/1981CA1097653A1 Process for the preparation of clavulanic acid esters
03/10/1981US4255332 Process for the preparation of potassium clavulanate from lithium clavulanate
03/04/1981EP0024372A1 Derivatives of clavulanic acid, their preparation and pharmaceutical compositions containing them
02/1981
02/25/1981EP0024123A1 Process for the preparation of derivatives of clavulanic acid
01/1981
01/27/1981CA1094563A1 Clavulanic acid derivatives
01/13/1981US4244965 Azetidinoyl ethers
01/07/1981EP0021836A1 Clavulanic acid derivatives, process for their preparation and pharmaceutical compositions containing them
12/1980
12/30/1980US4242262 Enhancement of penicillins and cephalosporins
11/1980
11/26/1980EP0019457A2 Clavulanic acid derivatives, their preparation and pharmaceutical compositions
11/26/1980EP0019148A1 Antibiotic suppressing the growth of microorganisms and its manufacture by fermentation
11/11/1980CA1089471A1 THERAPEUTIC COMPOUNDS CONTAINING .beta.-LACTAMS
11/04/1980US4232005 Antibacterial agents
10/1980
10/29/1980EP0018305A1 Oxapenem derivatives, their preparation, their use, pharmaceutical compositions containing them, diverse initial compounds and their preparation
10/29/1980EP0018203A1 Clavulanic acid derivatives, their preparation and use in pharmaceutical compositions
10/28/1980US4230622 Halogen derivatives of clavulaic acid
10/14/1980US4228174 Clavulanic acid ethers
10/14/1980US4228074 B-lactamase enzyme inhibitors chemical intermediates
08/1980
08/06/1980EP0013790A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them
07/1980
07/29/1980US4215128 Clavulanic acid derivatives their preparation and use
07/15/1980CA1081699A1 Clavulanic acid derivatives
06/1980
06/17/1980US4208325 Preparation of 1-oxapenicillins and 4-acyloxy azetidinone intermediates therefor
06/17/1980CA1079736A1 Crystalline calcium di-clavulanate dihydrate
06/10/1980US4207323 6-Substituted methyl penicillins, derivatives and analogues thereof
06/03/1980US4206120 Oxaazabicycloheptane antibiotics
05/1980
05/13/1980US4202819 2-(3-Alanyl)clavam antibiotic
04/1980
04/30/1980EP0010369A1 Clavulanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them
04/30/1980EP0010358A1 Beta-lactam compounds, processes for their preparation, compositions containing them, intermediates of use in their preparation and methods for the production thereof
04/02/1980EP0009302A1 Clavulanic acid derivatives and process for their preparation
04/01/1980CA1074802A1 Deoxyclavulanic acid, salts and esters
03/1980
03/19/1980EP0008899A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them
03/19/1980EP0008884A1 Derivatives of clavulanic acid, a process for their preparation and their compositions
03/19/1980EP0008877A1 Derivatives of clavulanic acid, a process for their preparation and their use
02/1980
02/26/1980CA1072471A1 Clavulanic acid antibiotic from streptomyces jumonjinensis
02/12/1980CA1071638A1 Process for the preparation of sodium and potassium salts of clavulanic acid
02/06/1980EP0007717A1 Clavulanic acid derivatives, a process for their preparation, their use, and pharmaceutical compositions containing them
02/05/1980US4187228 Antibacterial agents 5R, 2S-hydroxymethyl-3Z (2-hydroxy- or 2-alkoxyethylidene-1-aza-4-oxabicyclo[3,2,0]heptanone
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