Patents for C07D 503 - Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (648) |
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06/01/1983 | EP0080284A1 Derivatives of clavulanic acid, processes for their preparation and their use |
05/04/1983 | EP0078026A2 Antibiotic synthesis |
05/03/1983 | US4382084 Oxapenicillins; synergistic with penicillins and cephalosporins; enzyme inhibitors; enzymes/hydrolases/ |
04/13/1983 | EP0076369A1 Beta-lactam compounds |
04/12/1983 | CA1144540A1 6-AMIDINOPENICILLANIC ACID DERIVATIVES INCLUDING THE RADICAL OF A .beta.-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME |
02/08/1983 | US4372962 Clavulanic acid derivatives their preparation and use |
02/08/1983 | US4372946 Clavulanic acid derivatives their preparation and use |
01/18/1983 | US4369312 Method of producing oxo-containing azetidinone compounds |
01/11/1983 | US4368156 Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones |
01/05/1983 | EP0068715A1 Beta-lactam antibacterial agents, their preparation and use |
01/05/1983 | EP0068617A1 Derivatives of clavulanic acid, a process for their preparation and their use |
01/05/1983 | EP0068609A1 Derivatives of clavulanic acid, a process for their preparation and their use |
01/04/1983 | US4367175 Pure potassium salt of clavulanic acid |
12/22/1982 | EP0067518A1 Modified beta-lactam compounds |
12/14/1982 | CA1137479A1 Clavulanic acid derivatives, preparation and use |
11/16/1982 | US4359473 And b-lactamase inhibitors |
10/19/1982 | US4354974 Clavudienes |
10/13/1982 | EP0062407A1 Therapeutic compounds containing beta-lactams |
09/29/1982 | EP0061253A2 Process for the transfer of genetic material into actinomycete cells, prepared cells and method of culturing these cells and isolating a metabolite |
09/28/1982 | CA1132548A1 Derivatives of clavulanic acid, a process for their preparation and their use |
09/15/1982 | EP0060120A1 Process for preparing 4-haloazetidin-2-ones |
08/31/1982 | US4347183 Reacting a 4-substituted azedidin-2-one with an acid halide; reacting the product with a trialkyl phosphite |
08/25/1982 | EP0058317A1 Process for the preparation of 2-penem compounds |
08/24/1982 | CA1130294A1 Clavulanic acid derivatives, their preparation and use |
08/11/1982 | EP0057664A2 Clavam derivatives |
08/10/1982 | US4343807 Beta-lactamase inhibitors, bactericides, antibiotics |
08/10/1982 | US4343806 Benzylamino clavulanates and their production |
08/03/1982 | US4342772 β-Lactam compounds, antibacterial compositions thereof and method of use |
08/03/1982 | US4342749 Clavulanic acid derivatives a process for their preparation and their use in pharmaceutical compositions |
06/30/1982 | EP0055137A2 Method for concentrating beta-lactam antibiotic solution |
06/30/1982 | EP0055062A1 Compounds containing beta-lactams |
06/29/1982 | CA1126733A1 Process for the preparation of thioether derivatives of deoxyclavulanic acid |
06/16/1982 | EP0053893A1 Derivatives of clavulanic acid, their preparation and their use |
06/15/1982 | CA1125758A1 Clavulanic acid derivatives their preparation and use |
05/05/1982 | EP0050932A1 Therapeutic compounds containing beta-lactams |
04/20/1982 | US4325960 6-Amidinopenicillanic acid derivatives including the radical of a β-lactamase inhibitor |
04/13/1982 | CA1121821A1 .beta.-LACTAM CONTAINING COMPOUNDS, THEIR PREPARATION AND USE |
02/24/1982 | EP0046349A1 Clavulanic acid derivatives, their preparation and use |
02/09/1982 | US4314941 B-lactamase inhibitors, synergists for penicillins and cephalosporins |
02/02/1982 | CA1117532A1 Derivatives of clavulanic acid, their preparation and use |
01/19/1982 | CA1116603A1 PROCESS FOR THE PREPARATION OF .beta.-LACTAM COMPOUNDS |
01/13/1982 | EP0043546A2 7-Oxo-cephalosporins and 6-oxo-penicillins, their analogues and process for their preparation |
12/23/1981 | EP0042220A1 Process for the preparation of beta-lactam antibiotics |
12/01/1981 | US4303665 Methylaminodeoxy-clavulanic acid derivatives, their production and use |
11/17/1981 | US4301168 Tetrahydropyridyl derivatives of clavulanic acid, a process for their preparation and their use |
10/27/1981 | US4297345 Deoxy- and isodeoxyclavulanic acid symergistic with penicillin and cephalosporin anditiotics |
10/06/1981 | US4293555 6- and 6,6-Disubstituted-2-substituted-oxapen-2-em-3-carboxylic acids |
09/22/1981 | US4290949 Esters of 2-vinylclav-2-em-3-carboxylic acid and process for preparing same |
08/25/1981 | CA1107739A1 .beta.-LACTAM COMPOUNDS |
08/11/1981 | US4283531 Hydroxyalkylation |
07/21/1981 | CA1105467A1 .beta.-LACTAM COMPOUNDS, PREPARATION AND USE |
06/23/1981 | US4275067 Fungicide and b-lactamase inhibitors |
06/09/1981 | US4272439 6-(Substituted-hydroxymethylene penams) |
06/09/1981 | CA1102810A1 .beta.-LACTAM ANTIBACTERIAL AGENTS |
05/26/1981 | US4269773 Fused oxazolidine compounds |
05/06/1981 | EP0028083A1 Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them |
04/22/1981 | EP0027324A1 Derivatives of clavulanic acid, processes for their preparation and pharmaceutical compositions containing them |
04/22/1981 | EP0027323A1 Derivatives of clavulanic acid, processes for their preparation and pharmaceutical compositions containing them |
04/01/1981 | EP0026044A1 Amine salt of clavulanic acid, its preparation and use |
03/24/1981 | US4258050 Antibacterial agents |
03/18/1981 | EP0025287A1 Clavulanic acid derivatives, their preparation, pharmaceutical compositions containing them and their preparation |
03/18/1981 | EP0025271A1 Derivatives of clavulanic acid, their preparation and pharmaceutical compositions containing them |
03/17/1981 | US4256638 Chemical condensation of the corresponding diene derivative with a secondary amine; hydrogenolysis to form the acid |
03/17/1981 | CA1097654A1 Process for the preparation of ethers of clavulanic acid |
03/17/1981 | CA1097653A1 Process for the preparation of clavulanic acid esters |
03/10/1981 | US4255332 Process for the preparation of potassium clavulanate from lithium clavulanate |
03/04/1981 | EP0024372A1 Derivatives of clavulanic acid, their preparation and pharmaceutical compositions containing them |
02/25/1981 | EP0024123A1 Process for the preparation of derivatives of clavulanic acid |
01/27/1981 | CA1094563A1 Clavulanic acid derivatives |
01/13/1981 | US4244965 Azetidinoyl ethers |
01/07/1981 | EP0021836A1 Clavulanic acid derivatives, process for their preparation and pharmaceutical compositions containing them |
12/30/1980 | US4242262 Enhancement of penicillins and cephalosporins |
11/26/1980 | EP0019457A2 Clavulanic acid derivatives, their preparation and pharmaceutical compositions |
11/26/1980 | EP0019148A1 Antibiotic suppressing the growth of microorganisms and its manufacture by fermentation |
11/11/1980 | CA1089471A1 THERAPEUTIC COMPOUNDS CONTAINING .beta.-LACTAMS |
11/04/1980 | US4232005 Antibacterial agents |
10/29/1980 | EP0018305A1 Oxapenem derivatives, their preparation, their use, pharmaceutical compositions containing them, diverse initial compounds and their preparation |
10/29/1980 | EP0018203A1 Clavulanic acid derivatives, their preparation and use in pharmaceutical compositions |
10/28/1980 | US4230622 Halogen derivatives of clavulaic acid |
10/14/1980 | US4228174 Clavulanic acid ethers |
10/14/1980 | US4228074 B-lactamase enzyme inhibitors chemical intermediates |
08/06/1980 | EP0013790A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them |
07/29/1980 | US4215128 Clavulanic acid derivatives their preparation and use |
07/15/1980 | CA1081699A1 Clavulanic acid derivatives |
06/17/1980 | US4208325 Preparation of 1-oxapenicillins and 4-acyloxy azetidinone intermediates therefor |
06/17/1980 | CA1079736A1 Crystalline calcium di-clavulanate dihydrate |
06/10/1980 | US4207323 6-Substituted methyl penicillins, derivatives and analogues thereof |
06/03/1980 | US4206120 Oxaazabicycloheptane antibiotics |
05/13/1980 | US4202819 2-(3-Alanyl)clavam antibiotic |
04/30/1980 | EP0010369A1 Clavulanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them |
04/30/1980 | EP0010358A1 Beta-lactam compounds, processes for their preparation, compositions containing them, intermediates of use in their preparation and methods for the production thereof |
04/02/1980 | EP0009302A1 Clavulanic acid derivatives and process for their preparation |
04/01/1980 | CA1074802A1 Deoxyclavulanic acid, salts and esters |
03/19/1980 | EP0008899A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them |
03/19/1980 | EP0008884A1 Derivatives of clavulanic acid, a process for their preparation and their compositions |
03/19/1980 | EP0008877A1 Derivatives of clavulanic acid, a process for their preparation and their use |
02/26/1980 | CA1072471A1 Clavulanic acid antibiotic from streptomyces jumonjinensis |
02/12/1980 | CA1071638A1 Process for the preparation of sodium and potassium salts of clavulanic acid |
02/06/1980 | EP0007717A1 Clavulanic acid derivatives, a process for their preparation, their use, and pharmaceutical compositions containing them |
02/05/1980 | US4187228 Antibacterial agents 5R, 2S-hydroxymethyl-3Z (2-hydroxy- or 2-alkoxyethylidene-1-aza-4-oxabicyclo[3,2,0]heptanone |