Patents for C07D 503 - Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (648) |
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04/28/1992 | US5108747 Stable oxpenem-3-carboxylic acids as beta-lactamase inhibitors |
03/17/1992 | US5096899 Oxapenem-3-carboxylic acids |
03/11/1992 | EP0474038A1 New 2-tert. substituted methyloxapenem-3-carboxylic acids and esters, their preparation and use |
03/05/1992 | CA2050424A1 2-tert-substituted methyloxapenem-3-carboxylic acids and esters, a process for their preparation and their use |
11/12/1991 | US5064649 Cephalosporin derivatives |
10/31/1991 | WO1991016310A1 Antimicrobial quinolone thioureas |
10/31/1991 | CA2077435A1 Novel antimicrobial quinolone thioureas |
11/14/1990 | CN1010415B Process of the preparation of clavulanic acid and its salts and esters |
09/12/1990 | EP0387178A1 Process for the preparation of clavulinic acid and pharmaceutically acceptable salts from fermentation broths of Streptomyces sp. |
05/03/1990 | WO1990004591A1 Novel antimicrobial dithiocarbamoyl quinolones |
05/02/1990 | EP0366643A2 Novel antimicrobial dithiocarbamoyl quinolones |
05/02/1990 | EP0366193A2 Novel antimicrobial quinolonyl lactams |
05/02/1990 | EP0366189A2 Novel antimicrobial lactam-quinolones |
04/25/1990 | CN1041596A Stable oxapenem-3-carboxylic acids and their use as beta-lactamase inhibitors |
04/11/1990 | EP0362622A1 Use of stable oxapenem-3-carboxylic acids for the manufacture of beta-lactamase inhibiting medicaments |
04/04/1990 | CA2000058A1 Stable oxapenem-3-carboxylic acids as -lactamase inhibitors |
03/27/1990 | US4912224 Carboxyalkenamidocephalosporins |
03/21/1990 | EP0359536A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions |
01/10/1990 | EP0350210A2 Novel 6-amido-1-methyl-2-(substituted-thio)-carbapenems |
06/20/1989 | US4840944 Antibacterial beta-lactams, pharmaceuticals thereof and methods of using them |
04/26/1989 | EP0312813A2 Preparation of clavulanic acid and its salts and esters |
03/08/1989 | CN1031533A Stable oxapenem-3-carboxylic acids |
02/01/1989 | EP0301394A1 Stable oxapenem-3-carboxylic acids |
01/03/1989 | US4795809 Novel clavam derivatives and methods of making same |
08/03/1988 | EP0277008A1 Process for crystallization of potassium clavulanate |
07/05/1988 | CA1238910A1 Carboxyalkenoic acids |
05/31/1988 | US4748170 Carboxyalkenamidocephalosporins |
12/08/1987 | CA1230113A1 Method for producing chemical compounds |
07/28/1987 | USRE32465 AZA penem compounds |
07/28/1987 | US4683300 Deadcat reaction for making 9-deoxy-9-isocyanato clavulanates |
03/24/1987 | US4652560 Antibiotics, bactericides |
03/17/1987 | US4650795 Beta-lactamase inhibitors |
03/11/1987 | EP0213914A2 Clavam derivatives, preparation and intermediates therefor |
03/03/1987 | US4647659 Clavulanic acid amine salts, their preparation and use |
02/24/1987 | US4645671 Derivatives of clavulanic acid their preparation and their use |
01/06/1987 | US4634697 Bactericide |
11/11/1986 | US4622177 9-deoxy-9-isocyanato clavulante intermediates |
10/07/1986 | US4616084 Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3-hydroxy-1-dethia-1-oxacephem-4-carboxylic acids |
09/02/1986 | US4609495 Clavulanic acid ethers as antibacterial agents |
08/06/1986 | CN85108444A Process of the preparation of clavulanic acid and its salts and esters |
05/28/1986 | EP0182522A1 Preparation of clavulanic acid and its salts and esters |
04/22/1986 | US4584291 Antibiotics and beta-lactamase inhibitors |
02/18/1986 | US4571392 6-Substituted derivatives of clavulanic acid |
02/04/1986 | CA1200245A1 .beta.-LACTAM COMPOUNDS |
01/08/1986 | EP0167050A1 Clavulanate compounds, their preparation and use and intermediates thereof |
12/31/1985 | US4562182 Compounds containing beta-lactams |
12/24/1985 | US4560552 Antibiotics |
12/03/1985 | US4556559 Clavulanic acid ester, penicillin |
11/27/1985 | EP0162193A1 Novel 2-penem-type compounds and pharmaceutical compositions contaning them |
10/22/1985 | US4548815 Synergistic mixture of an oxapenicillin and a penicillin |
10/01/1985 | US4544549 Derivatives of clavulanic acid, their preparation and their use |
09/03/1985 | US4539202 Synergistic mixture with penicillins |
07/16/1985 | US4529734 2-Formyloxymethyl-clavam |
07/16/1985 | US4529720 Lactamase inhibition |
07/09/1985 | CA1190236A1 Antibiotic synthesis |
07/02/1985 | US4526783 Antibiotic from S. clavuligerus |
06/25/1985 | US4525353 Synergistic mixture of clavulanic acid and ticar cillin |
06/25/1985 | US4525352 Antibiotics |
06/18/1985 | US4524073 Oxapenicillins |
04/24/1985 | EP0137794A1 Clavam derivatives |
04/10/1985 | EP0136721A2 Carboxyalkenamidocephalosporins |
04/03/1985 | EP0135521A1 Clavam derivatives |
03/19/1985 | US4505894 Therapeutic compounds containing β-lactams |
03/06/1985 | EP0133670A2 Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3-hydroxy-1-dethia-1-oxacephem-4-carboxylic acids |
12/25/1984 | US4490295 Pure sodium salt of clavulanic acid |
12/25/1984 | US4490294 Pure salts of clavulanic acid, e.g. lithium clavulanate |
12/12/1984 | EP0127636A1 Compounds containing beta-lactams |
10/30/1984 | CA1177067A1 METHOD FOR CONCENTRATING .beta.-LACTAM ANTIBIOTIC SOLUTION |
09/25/1984 | CA1175052A1 Derivatives of clavulanic acid, their preparation and their use |
08/30/1984 | WO1984003282A1 Clavam derivatives |
08/16/1984 | WO1984003092A1 Clavam derivatives |
07/31/1984 | US4463010 1-Aza-[3.2.0]-bicycloheptane-2-carboxylic acid, ester or salt thereof |
07/10/1984 | CA1170658A1 Derivatives of clavulanic acid, a process for their preparation and their use |
07/04/1984 | EP0112685A1 Compounds containing beta-lactams |
06/19/1984 | US4455306 Method for concentrating β-lactam antibiotic solution |
06/12/1984 | US4454069 Clavulanic acid salts and their preparation from the tertiary butyl amine salt |
06/07/1984 | WO1984002134A1 COMPOUNDS CONTAINING beta-LACTAMS |
05/08/1984 | CA1167042A1 COMPOUNDS CONTAINING .beta.-LACTAMS |
05/01/1984 | US4446069 Process for the preparation of β-lactam antibiotics |
04/24/1984 | US4444754 Synergistic with penicillin |
03/28/1984 | EP0104010A1 Intermediates for clavulanic-acid derivatives |
03/20/1984 | US4438101 Synergistic oxapenicillin and amoxycillin |
03/06/1984 | US4435565 Enzyme inhibitors |
02/22/1984 | EP0101199A1 Beta-lactam compounds |
02/14/1984 | US4431658 Aza penem compounds |
01/31/1984 | US4428958 Therapeutic compounds containing β-lactams |
01/31/1984 | US4428937 Antibacterial agents |
01/24/1984 | US4427690 Esters of clavulanic acid |
01/24/1984 | US4427689 Clavulanic acid 9-deoxy-9-thia derivatives their preparation and use |
01/17/1984 | US4426389 Derivatives of clavulanic acid, a process for their preparation and their use |
01/17/1984 | US4426377 Clavulanic acid derivatives their preparation and use |
11/29/1983 | CA1157862A1 Amine salts of clavulanic acids, its preparation and use |
11/15/1983 | US4415584 Synergistic with penicillins and cephalosporins; penicillinase inhibitors |
10/11/1983 | US4409207 Derivatives of clavulanic acid, a process for their preparation and their use |
10/04/1983 | US4407751 Processes for preparing β-lactams |
08/30/1983 | CA1152999A1 Process for the preparation of derivatives of clavulanic acid |
07/05/1983 | CA1149390A1 Clavulanic acid derivatives, a process for their preparation and their use |
06/14/1983 | US4388300 Clavulanic acid derivatives, a process for their preparation and their use in pharmaceutical compositions |
06/01/1983 | EP0080286A1 Antibacterial compounds containing beta-lactams, processes for their preparation and their use |
06/01/1983 | EP0080285A1 Therapeutic compounds containing beta-lactams |