Patents
Patents for C07D 503 - Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (648)
04/1992
04/28/1992US5108747 Stable oxpenem-3-carboxylic acids as beta-lactamase inhibitors
03/1992
03/17/1992US5096899 Oxapenem-3-carboxylic acids
03/11/1992EP0474038A1 New 2-tert. substituted methyloxapenem-3-carboxylic acids and esters, their preparation and use
03/05/1992CA2050424A1 2-tert-substituted methyloxapenem-3-carboxylic acids and esters, a process for their preparation and their use
11/1991
11/12/1991US5064649 Cephalosporin derivatives
10/1991
10/31/1991WO1991016310A1 Antimicrobial quinolone thioureas
10/31/1991CA2077435A1 Novel antimicrobial quinolone thioureas
11/1990
11/14/1990CN1010415B Process of the preparation of clavulanic acid and its salts and esters
09/1990
09/12/1990EP0387178A1 Process for the preparation of clavulinic acid and pharmaceutically acceptable salts from fermentation broths of Streptomyces sp.
05/1990
05/03/1990WO1990004591A1 Novel antimicrobial dithiocarbamoyl quinolones
05/02/1990EP0366643A2 Novel antimicrobial dithiocarbamoyl quinolones
05/02/1990EP0366193A2 Novel antimicrobial quinolonyl lactams
05/02/1990EP0366189A2 Novel antimicrobial lactam-quinolones
04/1990
04/25/1990CN1041596A Stable oxapenem-3-carboxylic acids and their use as beta-lactamase inhibitors
04/11/1990EP0362622A1 Use of stable oxapenem-3-carboxylic acids for the manufacture of beta-lactamase inhibiting medicaments
04/04/1990CA2000058A1 Stable oxapenem-3-carboxylic acids as -lactamase inhibitors
03/1990
03/27/1990US4912224 Carboxyalkenamidocephalosporins
03/21/1990EP0359536A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions
01/1990
01/10/1990EP0350210A2 Novel 6-amido-1-methyl-2-(substituted-thio)-carbapenems
06/1989
06/20/1989US4840944 Antibacterial beta-lactams, pharmaceuticals thereof and methods of using them
04/1989
04/26/1989EP0312813A2 Preparation of clavulanic acid and its salts and esters
03/1989
03/08/1989CN1031533A Stable oxapenem-3-carboxylic acids
02/1989
02/01/1989EP0301394A1 Stable oxapenem-3-carboxylic acids
01/1989
01/03/1989US4795809 Novel clavam derivatives and methods of making same
08/1988
08/03/1988EP0277008A1 Process for crystallization of potassium clavulanate
07/1988
07/05/1988CA1238910A1 Carboxyalkenoic acids
05/1988
05/31/1988US4748170 Carboxyalkenamidocephalosporins
12/1987
12/08/1987CA1230113A1 Method for producing chemical compounds
07/1987
07/28/1987USRE32465 AZA penem compounds
07/28/1987US4683300 Deadcat reaction for making 9-deoxy-9-isocyanato clavulanates
03/1987
03/24/1987US4652560 Antibiotics, bactericides
03/17/1987US4650795 Beta-lactamase inhibitors
03/11/1987EP0213914A2 Clavam derivatives, preparation and intermediates therefor
03/03/1987US4647659 Clavulanic acid amine salts, their preparation and use
02/1987
02/24/1987US4645671 Derivatives of clavulanic acid their preparation and their use
01/1987
01/06/1987US4634697 Bactericide
11/1986
11/11/1986US4622177 9-deoxy-9-isocyanato clavulante intermediates
10/1986
10/07/1986US4616084 Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3-hydroxy-1-dethia-1-oxacephem-4-carboxylic acids
09/1986
09/02/1986US4609495 Clavulanic acid ethers as antibacterial agents
08/1986
08/06/1986CN85108444A Process of the preparation of clavulanic acid and its salts and esters
05/1986
05/28/1986EP0182522A1 Preparation of clavulanic acid and its salts and esters
04/1986
04/22/1986US4584291 Antibiotics and beta-lactamase inhibitors
02/1986
02/18/1986US4571392 6-Substituted derivatives of clavulanic acid
02/04/1986CA1200245A1 .beta.-LACTAM COMPOUNDS
01/1986
01/08/1986EP0167050A1 Clavulanate compounds, their preparation and use and intermediates thereof
12/1985
12/31/1985US4562182 Compounds containing beta-lactams
12/24/1985US4560552 Antibiotics
12/03/1985US4556559 Clavulanic acid ester, penicillin
11/1985
11/27/1985EP0162193A1 Novel 2-penem-type compounds and pharmaceutical compositions contaning them
10/1985
10/22/1985US4548815 Synergistic mixture of an oxapenicillin and a penicillin
10/01/1985US4544549 Derivatives of clavulanic acid, their preparation and their use
09/1985
09/03/1985US4539202 Synergistic mixture with penicillins
07/1985
07/16/1985US4529734 2-Formyloxymethyl-clavam
07/16/1985US4529720 Lactamase inhibition
07/09/1985CA1190236A1 Antibiotic synthesis
07/02/1985US4526783 Antibiotic from S. clavuligerus
06/1985
06/25/1985US4525353 Synergistic mixture of clavulanic acid and ticar cillin
06/25/1985US4525352 Antibiotics
06/18/1985US4524073 Oxapenicillins
04/1985
04/24/1985EP0137794A1 Clavam derivatives
04/10/1985EP0136721A2 Carboxyalkenamidocephalosporins
04/03/1985EP0135521A1 Clavam derivatives
03/1985
03/19/1985US4505894 Therapeutic compounds containing β-lactams
03/06/1985EP0133670A2 Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3-hydroxy-1-dethia-1-oxacephem-4-carboxylic acids
12/1984
12/25/1984US4490295 Pure sodium salt of clavulanic acid
12/25/1984US4490294 Pure salts of clavulanic acid, e.g. lithium clavulanate
12/12/1984EP0127636A1 Compounds containing beta-lactams
10/1984
10/30/1984CA1177067A1 METHOD FOR CONCENTRATING .beta.-LACTAM ANTIBIOTIC SOLUTION
09/1984
09/25/1984CA1175052A1 Derivatives of clavulanic acid, their preparation and their use
08/1984
08/30/1984WO1984003282A1 Clavam derivatives
08/16/1984WO1984003092A1 Clavam derivatives
07/1984
07/31/1984US4463010 1-Aza-[3.2.0]-bicycloheptane-2-carboxylic acid, ester or salt thereof
07/10/1984CA1170658A1 Derivatives of clavulanic acid, a process for their preparation and their use
07/04/1984EP0112685A1 Compounds containing beta-lactams
06/1984
06/19/1984US4455306 Method for concentrating β-lactam antibiotic solution
06/12/1984US4454069 Clavulanic acid salts and their preparation from the tertiary butyl amine salt
06/07/1984WO1984002134A1 COMPOUNDS CONTAINING beta-LACTAMS
05/1984
05/08/1984CA1167042A1 COMPOUNDS CONTAINING .beta.-LACTAMS
05/01/1984US4446069 Process for the preparation of β-lactam antibiotics
04/1984
04/24/1984US4444754 Synergistic with penicillin
03/1984
03/28/1984EP0104010A1 Intermediates for clavulanic-acid derivatives
03/20/1984US4438101 Synergistic oxapenicillin and amoxycillin
03/06/1984US4435565 Enzyme inhibitors
02/1984
02/22/1984EP0101199A1 Beta-lactam compounds
02/14/1984US4431658 Aza penem compounds
01/1984
01/31/1984US4428958 Therapeutic compounds containing β-lactams
01/31/1984US4428937 Antibacterial agents
01/24/1984US4427690 Esters of clavulanic acid
01/24/1984US4427689 Clavulanic acid 9-deoxy-9-thia derivatives their preparation and use
01/17/1984US4426389 Derivatives of clavulanic acid, a process for their preparation and their use
01/17/1984US4426377 Clavulanic acid derivatives their preparation and use
11/1983
11/29/1983CA1157862A1 Amine salts of clavulanic acids, its preparation and use
11/15/1983US4415584 Synergistic with penicillins and cephalosporins; penicillinase inhibitors
10/1983
10/11/1983US4409207 Derivatives of clavulanic acid, a process for their preparation and their use
10/04/1983US4407751 Processes for preparing β-lactams
08/1983
08/30/1983CA1152999A1 Process for the preparation of derivatives of clavulanic acid
07/1983
07/05/1983CA1149390A1 Clavulanic acid derivatives, a process for their preparation and their use
06/1983
06/14/1983US4388300 Clavulanic acid derivatives, a process for their preparation and their use in pharmaceutical compositions
06/01/1983EP0080286A1 Antibacterial compounds containing beta-lactams, processes for their preparation and their use
06/01/1983EP0080285A1 Therapeutic compounds containing beta-lactams
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