Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960) |
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04/25/2000 | US6054436 Regulated apoptosis |
04/25/2000 | CA2155728C Regulated transcription of targeted genes and other biological events |
04/20/2000 | WO2000021959A1 4,5-dihydro-isoxazole derivatives and their pharmaceutical use |
04/20/2000 | WO2000006525A9 Synthesis of combinatorial libraries of compounds reminiscent of natural products |
04/19/2000 | EP0711297B1 Rapamycin derivative with antimicrobial, anticancer and immunomodulation activity |
04/19/2000 | CN1051547C Beta-lactams derivative and its prepn.and use |
04/18/2000 | US6051703 Broad spectrum antibiotic |
04/18/2000 | US6051581 Spiro-azabicyclic compounds useful in therapy |
04/13/2000 | WO2000020601A2 Polyketide synthase enzymes and recombinant dna constructs therefor |
04/12/2000 | EP0991638A1 NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS |
04/12/2000 | CN1250447A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides |
04/11/2000 | US6048977 Clavulanic acid and salts thereof |
04/11/2000 | US6048870 Mannosidase inhibitor; immunostimulant |
04/06/2000 | WO2000018769A2 INDOLO[2,1-b]QUINAZOLE-6,12-DIONE ANTIMALARIAL COMPOUNDS AND METHODS OF TREATING MALARIA THEREWITH |
04/06/2000 | WO2000018407A1 Methods for preventing/treating damage to sensory hair cells and cochlear neurons |
04/06/2000 | CA2317711A1 Indolo[2,1-b]quinazole-6,12-dione antimalarial compounds and methods of treating malaria therewith |
04/05/2000 | EP0990654A1 Substituted cyclobutylamine derivatives |
04/05/2000 | EP0990650A1 Tricyclic pyrrole or pyrazole derivatives |
04/05/2000 | EP0989857A1 Novel therapeutic agents that modulate enzymatic processes |
04/05/2000 | CN1249753A Farnesyl transferase inhibiting 1,8-annelated quinolinone derivs. substd. with N- or C-linked imidazoles |
04/04/2000 | US6046211 Amidino derivatives useful as nitric oxide synthase inhibitors |
04/04/2000 | US6046047 Genetic construct encoding a chimeric protein with a domain which binds and crosslinks a synthetic, membrane permeable, non-peptide ligand and domain to cause cellular localization of complex; for gene therapy and inducible gene expression |
04/04/2000 | US6045822 Protein kinase c inhibitor, antitumor agent having stability in blood |
04/04/2000 | CA2204739C Macrocyclic lactone compounds and their production process |
03/30/2000 | WO2000017207A1 3,4-dihydro -n-[[1-(3 -hydroxybutyl) -4-piperidinyl] methyl] -2h-[1,3] oxazino[3, 2-a]indole -10-carboxamide as 5-ht(4) receptor antagonist |
03/30/2000 | WO2000016603A2 Bridged heterocyclic derivatives |
03/30/2000 | WO1999062908A3 Cell adhesion-inhibiting antinflammatory compounds |
03/30/2000 | CA2344376A1 Bridged heterocyclic derivatives |
03/29/2000 | EP0734389B1 Rapamycin derivatives useful as immunosuppressants |
03/29/2000 | CN1050844C Protein kinase C inhibitors |
03/28/2000 | US6043082 Two genetic constructs encoding chimeric proteins, each with ligand binding domain to complex with the other protein; one protein also with domain which induces biological process, the other having intracelluar targeting domain; gene therapy |
03/28/2000 | CA2180658C Treatment of platelet derived growth factor related disorders such as cancers using inhibitors of platelet derived growth receptor |
03/28/2000 | CA1340939C Photochromic compound |
03/23/2000 | WO2000015208A2 New use of immunosupressants for mmp-mediated diseases |
03/23/2000 | WO1999052892A3 Novel herbicides |
03/22/2000 | EP0987254A1 Novel cyclic diamine compounds and medicine containing the same |
03/22/2000 | CN1248255A 3-heterocyclyl-substituted benzoyl derivatives |
03/16/2000 | WO2000014086A1 Chemokine receptor antagonists and methods of use therefor |
03/16/2000 | WO1999064047A9 Novel antiviral compounds |
03/16/2000 | WO1999063929A9 Multibinding inhibitors of microsomal triglyceride transferase protein |
03/16/2000 | CA2342882A1 Chemokine receptor antagonists and methods of use therefor |
03/15/2000 | CN1247534A Benzofurazan compounds which enhance AMPA receptor activity |
03/15/2000 | CN1050359C Diterpene salicylate alkaloid, prepn. and use thereof |
03/15/2000 | CN1050358C New tetracyclic piperidine and 1,4-oxazine compounds, its prepn. and pharmaceutical compsns. containing them |
03/14/2000 | US6037468 Stereoselective preparation of pyranosylated indolocarbazoles by ring expansion of corresponding furanosylated indolocarbazole |
03/14/2000 | US6037340 Have biological activity including anti-cancer activity |
03/09/2000 | WO2000005230A8 Pyrazole derivatives and salts thereof |
03/08/2000 | EP0983348A2 Polyketides and their synthesis and use |
03/08/2000 | EP0983276A1 Novel photochromic spirooxazine compounds, their use in ophthalmic optics |
03/08/2000 | EP0854857B1 Method of preparing optically active alpha-amino acids and alpha-amino acid derivatives |
03/08/2000 | CN1050121C Preparation method of substituted aryl-haloalkylpyrazoles compound |
03/02/2000 | WO2000011003A1 ISOXAZOLO[4,5-d]PYRIMIDINES AS CRF ANTAGONISTS |
03/02/2000 | WO1999064054A9 Multibinding inhibitors of topoisomerase |
03/02/2000 | WO1999063937A3 Multivalent macrolide antibiotics |
03/02/2000 | CA2339188A1 Isoxazolo¬4,5-d|pyrimidines as crf antagonists |
03/01/2000 | EP0982375A1 Mixtures of reactive dyestuffs and their use in dyeing and printing fibre materials containing hydroxyle or carbonamid groups |
03/01/2000 | EP0981530A1 Compounds on the basis of polyalkyl-1-oxa-diazaspirodecane compounds |
03/01/2000 | EP0981521A2 Novel macrocyclic compounds as metalloprotease inhibitors |
03/01/2000 | EP0673374B1 Pharmaceutical composition containing bicyclic type compounds |
03/01/2000 | EP0513387B1 Thiazole derivatives as active oxygen inhibitors |
02/29/2000 | US6031093 Solid salts of clavulanic acid |
02/24/2000 | WO2000009510A1 Photocyclized rapamycins |
02/24/2000 | WO2000009509A2 Process for the large-scale synthesis of 4,10-dinitro -2,6,8,12- tetraoxa- 4,10-diazatetracyclo- [5.5.0.0?5,903,11¿]- dodecane |
02/24/2000 | WO2000009109A2 Pipecolic acid derivatives for vision and memory disorders |
02/24/2000 | WO2000002883A3 Photochromic six-membered heterocyclic-fused naphthopyrans |
02/24/2000 | CA2344520A1 Pipecolic acid derivatives for vision and memory disorders |
02/24/2000 | CA2340700A1 Photocyclized rapamycins |
02/23/2000 | EP0980373A1 Reverse-turn mimetics and methods relating thereto |
02/23/2000 | EP0980259A1 Use of a cd40:cd154 binding interruptor to prevent counter adaptive immune responses, particularly graft rejection |
02/23/2000 | CN1245499A 8-azabicyclo [3,2,1] octane, 8-azabicyclo [3,2,1] oct-6-ene-,9-azabicyclo [3,2,1] nonane-, 9-aza-3-oxabicyclo [3,3,1] nonane- and 9-aza-3-thiabicyclo[3,3,1] nonane derivatives, their preparation and |
02/23/2000 | CN1245498A 8-azabicyclo [3,2,1] octane derivatives their preparation and their use as insecticides |
02/23/2000 | CN1245428A Use of 7-(2-oxa-5,8-diazabicyclo [4,3,0] non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for treatment of helicobacter pylori infections and associated gastroduodenal |
02/22/2000 | US6028097 Method of immunosuppression |
02/22/2000 | CA2081356C Derivatives and analogues of 2-deoxy-2,3-didehydro-n- acetyl neuraminic acid and their use as antiviral agents |
02/17/2000 | WO2000008001A1 Substituted isoxazole as estrogen receptor modulators |
02/17/2000 | WO2000007996A2 Pyrazoles as estrogen receptor modulators |
02/17/2000 | WO1999055332A8 Medicinal compositions |
02/16/2000 | CN1244528A Di- Or triaza-spiral [4,5] decane derivative |
02/15/2000 | US6025498 4-thiocarbamoyl-1-(3-pyrazolyl)-pyrazoles and their use as herbicides |
02/15/2000 | US6025478 High reactivity and fixing capacity, good low temperature dyeing, good color intensity, lightfastness, washfastness |
02/15/2000 | US6025378 Antiatherosclerotic action. |
02/10/2000 | WO2000006578A1 Pyridobenzoxazine derivatives and process for producing the same |
02/10/2000 | WO2000006577A1 OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF |
02/10/2000 | WO2000006576A1 Compounds |
02/10/2000 | WO2000006564A1 Disubstituted maleimide compounds and medicinal utilization thereof |
02/10/2000 | WO2000006525A2 Synthesis of combinatorial libraries of compounds reminiscent of natural products |
02/10/2000 | WO2000006154A1 Urokinase production inhibitors, angiogenesis inhibitors and methods of prevention or treatment with both |
02/10/2000 | WO1999063939A3 Multibinding inhibitors of cyclooxygenase-2 |
02/10/2000 | CA2338866A1 Disubstituted maleimide compound and pharmaceutical use thereof |
02/09/2000 | EP0978544A1 Reactive dye mixtures and their use for dyeing and printing fibrous materials containing hydroxyl and/or carbonamide groups |
02/09/2000 | EP0978543A1 Reactive dye mixtures and their use for dyeing and printing fibrous materials containing hydroxyl and/or carbonamide groups |
02/09/2000 | EP0977565A1 Pharmaceutical composition |
02/08/2000 | US6022497 Photochromic six-membered heterocyclic-fused naphthopyrans |
02/03/2000 | WO2000005234A1 NF-λB INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT |
02/03/2000 | WO2000005230A1 Pyrazole derivatives and salts thereof |
02/03/2000 | WO1999063929A3 Multibinding inhibitors of microsomal triglyceride transferase protein |
02/02/2000 | EP0976794A1 Reactive dyestuffs and their use in dyeing and printing fibre materials containing hydroxyle and/or carbonamide groups |
02/02/2000 | EP0975639A1 Compounds |
02/01/2000 | US6020343 (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors |
02/01/2000 | US6019914 Spiro(indoline-(2,3')-benzoxazine) type, include at least one electron-withdrawing group attached to the benzoxazine structure in 5' or 6' position by a chain containing at least one ethylenic double bond. |