Patents
Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960)
04/2000
04/25/2000US6054436 Regulated apoptosis
04/25/2000CA2155728C Regulated transcription of targeted genes and other biological events
04/20/2000WO2000021959A1 4,5-dihydro-isoxazole derivatives and their pharmaceutical use
04/20/2000WO2000006525A9 Synthesis of combinatorial libraries of compounds reminiscent of natural products
04/19/2000EP0711297B1 Rapamycin derivative with antimicrobial, anticancer and immunomodulation activity
04/19/2000CN1051547C Beta-lactams derivative and its prepn.and use
04/18/2000US6051703 Broad spectrum antibiotic
04/18/2000US6051581 Spiro-azabicyclic compounds useful in therapy
04/13/2000WO2000020601A2 Polyketide synthase enzymes and recombinant dna constructs therefor
04/12/2000EP0991638A1 NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS
04/12/2000CN1250447A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides
04/11/2000US6048977 Clavulanic acid and salts thereof
04/11/2000US6048870 Mannosidase inhibitor; immunostimulant
04/06/2000WO2000018769A2 INDOLO[2,1-b]QUINAZOLE-6,12-DIONE ANTIMALARIAL COMPOUNDS AND METHODS OF TREATING MALARIA THEREWITH
04/06/2000WO2000018407A1 Methods for preventing/treating damage to sensory hair cells and cochlear neurons
04/06/2000CA2317711A1 Indolo[2,1-b]quinazole-6,12-dione antimalarial compounds and methods of treating malaria therewith
04/05/2000EP0990654A1 Substituted cyclobutylamine derivatives
04/05/2000EP0990650A1 Tricyclic pyrrole or pyrazole derivatives
04/05/2000EP0989857A1 Novel therapeutic agents that modulate enzymatic processes
04/05/2000CN1249753A Farnesyl transferase inhibiting 1,8-annelated quinolinone derivs. substd. with N- or C-linked imidazoles
04/04/2000US6046211 Amidino derivatives useful as nitric oxide synthase inhibitors
04/04/2000US6046047 Genetic construct encoding a chimeric protein with a domain which binds and crosslinks a synthetic, membrane permeable, non-peptide ligand and domain to cause cellular localization of complex; for gene therapy and inducible gene expression
04/04/2000US6045822 Protein kinase c inhibitor, antitumor agent having stability in blood
04/04/2000CA2204739C Macrocyclic lactone compounds and their production process
03/2000
03/30/2000WO2000017207A1 3,4-dihydro -n-[[1-(3 -hydroxybutyl) -4-piperidinyl] methyl] -2h-[1,3] oxazino[3, 2-a]indole -10-carboxamide as 5-ht(4) receptor antagonist
03/30/2000WO2000016603A2 Bridged heterocyclic derivatives
03/30/2000WO1999062908A3 Cell adhesion-inhibiting antinflammatory compounds
03/30/2000CA2344376A1 Bridged heterocyclic derivatives
03/29/2000EP0734389B1 Rapamycin derivatives useful as immunosuppressants
03/29/2000CN1050844C Protein kinase C inhibitors
03/28/2000US6043082 Two genetic constructs encoding chimeric proteins, each with ligand binding domain to complex with the other protein; one protein also with domain which induces biological process, the other having intracelluar targeting domain; gene therapy
03/28/2000CA2180658C Treatment of platelet derived growth factor related disorders such as cancers using inhibitors of platelet derived growth receptor
03/28/2000CA1340939C Photochromic compound
03/23/2000WO2000015208A2 New use of immunosupressants for mmp-mediated diseases
03/23/2000WO1999052892A3 Novel herbicides
03/22/2000EP0987254A1 Novel cyclic diamine compounds and medicine containing the same
03/22/2000CN1248255A 3-heterocyclyl-substituted benzoyl derivatives
03/16/2000WO2000014086A1 Chemokine receptor antagonists and methods of use therefor
03/16/2000WO1999064047A9 Novel antiviral compounds
03/16/2000WO1999063929A9 Multibinding inhibitors of microsomal triglyceride transferase protein
03/16/2000CA2342882A1 Chemokine receptor antagonists and methods of use therefor
03/15/2000CN1247534A Benzofurazan compounds which enhance AMPA receptor activity
03/15/2000CN1050359C Diterpene salicylate alkaloid, prepn. and use thereof
03/15/2000CN1050358C New tetracyclic piperidine and 1,4-oxazine compounds, its prepn. and pharmaceutical compsns. containing them
03/14/2000US6037468 Stereoselective preparation of pyranosylated indolocarbazoles by ring expansion of corresponding furanosylated indolocarbazole
03/14/2000US6037340 Have biological activity including anti-cancer activity
03/09/2000WO2000005230A8 Pyrazole derivatives and salts thereof
03/08/2000EP0983348A2 Polyketides and their synthesis and use
03/08/2000EP0983276A1 Novel photochromic spirooxazine compounds, their use in ophthalmic optics
03/08/2000EP0854857B1 Method of preparing optically active alpha-amino acids and alpha-amino acid derivatives
03/08/2000CN1050121C Preparation method of substituted aryl-haloalkylpyrazoles compound
03/02/2000WO2000011003A1 ISOXAZOLO[4,5-d]PYRIMIDINES AS CRF ANTAGONISTS
03/02/2000WO1999064054A9 Multibinding inhibitors of topoisomerase
03/02/2000WO1999063937A3 Multivalent macrolide antibiotics
03/02/2000CA2339188A1 Isoxazolo¬4,5-d|pyrimidines as crf antagonists
03/01/2000EP0982375A1 Mixtures of reactive dyestuffs and their use in dyeing and printing fibre materials containing hydroxyle or carbonamid groups
03/01/2000EP0981530A1 Compounds on the basis of polyalkyl-1-oxa-diazaspirodecane compounds
03/01/2000EP0981521A2 Novel macrocyclic compounds as metalloprotease inhibitors
03/01/2000EP0673374B1 Pharmaceutical composition containing bicyclic type compounds
03/01/2000EP0513387B1 Thiazole derivatives as active oxygen inhibitors
02/2000
02/29/2000US6031093 Solid salts of clavulanic acid
02/24/2000WO2000009510A1 Photocyclized rapamycins
02/24/2000WO2000009509A2 Process for the large-scale synthesis of 4,10-dinitro -2,6,8,12- tetraoxa- 4,10-diazatetracyclo- [5.5.0.0?5,903,11¿]- dodecane
02/24/2000WO2000009109A2 Pipecolic acid derivatives for vision and memory disorders
02/24/2000WO2000002883A3 Photochromic six-membered heterocyclic-fused naphthopyrans
02/24/2000CA2344520A1 Pipecolic acid derivatives for vision and memory disorders
02/24/2000CA2340700A1 Photocyclized rapamycins
02/23/2000EP0980373A1 Reverse-turn mimetics and methods relating thereto
02/23/2000EP0980259A1 Use of a cd40:cd154 binding interruptor to prevent counter adaptive immune responses, particularly graft rejection
02/23/2000CN1245499A 8-azabicyclo [3,2,1] octane, 8-azabicyclo [3,2,1] oct-6-ene-,9-azabicyclo [3,2,1] nonane-, 9-aza-3-oxabicyclo [3,3,1] nonane- and 9-aza-3-thiabicyclo[3,3,1] nonane derivatives, their preparation and
02/23/2000CN1245498A 8-azabicyclo [3,2,1] octane derivatives their preparation and their use as insecticides
02/23/2000CN1245428A Use of 7-(2-oxa-5,8-diazabicyclo [4,3,0] non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for treatment of helicobacter pylori infections and associated gastroduodenal
02/22/2000US6028097 Method of immunosuppression
02/22/2000CA2081356C Derivatives and analogues of 2-deoxy-2,3-didehydro-n- acetyl neuraminic acid and their use as antiviral agents
02/17/2000WO2000008001A1 Substituted isoxazole as estrogen receptor modulators
02/17/2000WO2000007996A2 Pyrazoles as estrogen receptor modulators
02/17/2000WO1999055332A8 Medicinal compositions
02/16/2000CN1244528A Di- Or triaza-spiral [4,5] decane derivative
02/15/2000US6025498 4-thiocarbamoyl-1-(3-pyrazolyl)-pyrazoles and their use as herbicides
02/15/2000US6025478 High reactivity and fixing capacity, good low temperature dyeing, good color intensity, lightfastness, washfastness
02/15/2000US6025378 Antiatherosclerotic action.
02/10/2000WO2000006578A1 Pyridobenzoxazine derivatives and process for producing the same
02/10/2000WO2000006577A1 OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF
02/10/2000WO2000006576A1 Compounds
02/10/2000WO2000006564A1 Disubstituted maleimide compounds and medicinal utilization thereof
02/10/2000WO2000006525A2 Synthesis of combinatorial libraries of compounds reminiscent of natural products
02/10/2000WO2000006154A1 Urokinase production inhibitors, angiogenesis inhibitors and methods of prevention or treatment with both
02/10/2000WO1999063939A3 Multibinding inhibitors of cyclooxygenase-2
02/10/2000CA2338866A1 Disubstituted maleimide compound and pharmaceutical use thereof
02/09/2000EP0978544A1 Reactive dye mixtures and their use for dyeing and printing fibrous materials containing hydroxyl and/or carbonamide groups
02/09/2000EP0978543A1 Reactive dye mixtures and their use for dyeing and printing fibrous materials containing hydroxyl and/or carbonamide groups
02/09/2000EP0977565A1 Pharmaceutical composition
02/08/2000US6022497 Photochromic six-membered heterocyclic-fused naphthopyrans
02/03/2000WO2000005234A1 NF-λB INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT
02/03/2000WO2000005230A1 Pyrazole derivatives and salts thereof
02/03/2000WO1999063929A3 Multibinding inhibitors of microsomal triglyceride transferase protein
02/02/2000EP0976794A1 Reactive dyestuffs and their use in dyeing and printing fibre materials containing hydroxyle and/or carbonamide groups
02/02/2000EP0975639A1 Compounds
02/01/2000US6020343 (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
02/01/2000US6019914 Spiro(indoline-(2,3')-benzoxazine) type, include at least one electron-withdrawing group attached to the benzoxazine structure in 5' or 6' position by a chain containing at least one ethylenic double bond.