Patents
Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960)
06/1999
06/02/1999EP0630376B1 Condensed indole derivatives as 5-ht4-receptor antagonists
06/01/1999US5908937 Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives
06/01/1999US5908841 5,11-dihydro-6H-dipyrido 3,2-b:2',3'-e!azepine-6-ones and their use in the prevention of treatment of HIV infection
05/1999
05/27/1999DE19751948A1 Rapid preparation of 8-alkoxy-quinolone-carboxylic acid derivative antibacterial agent, e.g. gatifloxacin, in high purity
05/20/1999WO1999016753A3 Tricyclic 3-oxo-propanenitrile compounds
05/20/1999DE19750701A1 Reaction of F-substituted triazine and pyrimidine compounds with amino compounds
05/20/1999DE19750085A1 New 2-phenyl-imidazotriazinone derivatives used for treating cardiovascular, cerebrovascular and urogenital disorders
05/19/1999EP0915886A1 Novel homoazaadamantane spirooxazines and use thereof in ophthalmic optics
05/14/1999WO1999023170A1 Triphendioxazine colorants
05/11/1999US5902882 Asymmetrically hydrogenating an azepine compound in the presence of a ruthenium-diphosphine complex catalyst
05/11/1999US5902814 Treating psychotic disorder, intellectual disorders and anxiety, such as attention deficit hyperactivity disorder and schizophrenia
05/06/1999WO1999021422A1 Treatment of schizophrenia with ampakines and neuroleptics
05/06/1999EP0912184A1 Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction
05/06/1999EP0688320B1 Tricyclic benzodiazepins, their use and preparation
05/06/1999EP0626068B1 Luminescent lanthanide chelates
05/06/1999DE19748356A1 Triphendioxazinfarbstoffe Triphendioxazine
05/06/1999CA2306817A1 Treatment of schizophrenia with ampakines and neuroleptics
05/04/1999CA2074641C Method of treating ocular inflammation
04/1999
04/29/1999WO1999020630A1 Photochromic compounds
04/29/1999WO1999020609A1 Inhibitors of farnesyl-protein transferase
04/29/1999CA2306312A1 Inhibitors of farnesyl-protein transferase
04/28/1999EP0911337A1 New triphendioxazine compounds
04/28/1999EP0911328A1 Substituted aminocycloalkylpyrrolidine derivatives
04/28/1999EP0910633A2 Polyketides and their synthesis
04/28/1999EP0740669B1 Azatrioxaspiroalkenes as parasiticides
04/28/1999CN1215391A 6-phenylpyridyl-2-amine derivatives
04/28/1999CN1043142C Quinolone and naphthyridone-carboxylic acid derivatives and preparation process
04/22/1999WO1999019329A1 A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity
04/22/1999WO1999018941A2 Ih-MODULATORS
04/22/1999WO1999011624B1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
04/22/1999CA2305180A1 Ih-modulators
04/22/1999CA2274658A1 A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity
04/21/1999EP0909327A2 Erythromycins and process for their preparation
04/21/1999CN1214686A Derivatives of camptothecin for use in treating cancer
04/21/1999CN1214631A Use of rapamycin derivatives in vasculopathies and xenotransplantation
04/15/1999WO1999018092A1 High char yield benzoxazines
04/15/1999WO1999018076A1 The preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
04/15/1999WO1999008668A3 Combination of tyrosine kinase inhibitor and chemical castration to treat prostate cancer
04/15/1999CA2305582A1 High char yield benzoxazines
04/15/1999CA2303449A1 The preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
04/14/1999EP0595924B1 Platelet activating factor antagonists
04/14/1999CN1042936C Substituted aminoquinolone compound, its application and medicinal compsns. containing same
04/13/1999CA1340493C Pyridone carboxylic acid derivatives and salts thereof, process for producing the same and antibacterial agents comprising the same
04/08/1999WO1999016772A1 Photochromic spiro(indoline) fluoranthenoxazine compounds
04/08/1999WO1999016771A1 Condensed benzothiopyranic compounds
04/08/1999WO1999016769A1 Resolution of optically-active compounds
04/08/1999WO1999016753A2 Tricyclic 3-oxo-propanenitrile compounds
04/08/1999WO1998054308A3 Polyketides and their synthesis and use
04/08/1999CA2302027A1 Condensed benzothiopyranic compounds
04/08/1999CA2302025A1 Tricyclic 3-oxo-propanenitrile compounds
04/07/1999CN1213373A Pyrimidin-4-one-derivatives as pesticide
04/06/1999US5892040 Process for the manufacture of a tricyclic compound
04/06/1999US5892037 Polymeric adducts of hindered amine-epoxides as stabilizers
04/06/1999CA1340487C Ph-neutral aqueous solutions of quinolone-carboxylic acids
04/01/1999WO1999015530A1 Tetrazole-containing rapamycin analogs with shortened half-lives
04/01/1999WO1999015500A1 Substituted oxindole derivatives as protein tyrosine kinase and as protein serine/threonine kinase inhibitors
04/01/1999WO1999014998A2 Method for preventing and treating hearing loss using sensorineurotrophic compounds
04/01/1999CA2304647A1 Method for preventing and treating hearing loss using sensorineurotophic compounds
04/01/1999CA2302572A1 Substituted oxindole derivatives as protein tyrosine kinase and as protein serine/threonine kinase inhibitors
03/1999
03/31/1999CN1212256A Quinolone-and naphthyridone-carboxylic acid derivatives
03/30/1999US5888992 Polar substituted hydrocarbons
03/25/1999WO1998051665A3 Novel macrocyclic compounds as metalloprotease inhibitors
03/24/1999EP0902684A1 Hexahydro-pyrido(4,3-b)indole derivatives as antipsychotic drugs
03/24/1999EP0728181B1 Quarternary oxaziridinium salts as bleaching compounds
03/24/1999CN1211985A Fused imidazole derivatives as multidrug resistance modulators
03/24/1999CN1211920A Thieno (2,3-b) pyrazolo (3,4-d) pyridin-3-ones to enhance erythropoiesis
03/23/1999US5886043 Antiarthritic agents, antitumor agents, antiinflammatory agents
03/23/1999US5886024 Thiophene-containing butonic acid derivatives as matrix metalloprotease inhibitors
03/18/1999WO1999012937A2 Novel triphenodioxazines and their use as blue, light fast aox and heavy metal free substances
03/18/1999WO1999012929A2 Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom
03/18/1999WO1999012915A1 Benzoxazine and benzothiazine derivatives and their use in pharmaceuticals
03/18/1999WO1999012901A1 Substituted 2-pyrrolidinone activators of pkc
03/18/1999DE19739983A1 Neue Triphendioxazine New triphendioxazines
03/18/1999CA2303440A1 Benzoxazine and benzothiazine derivatives and their use in pharmaceuticals
03/18/1999CA2303146A1 Substituted 2-pyrrolidinone activators of pkc
03/17/1999EP0901494A1 Photochromic spiroxazines with asymmetric monocyclic substituent, compositions and articles containing them
03/17/1999EP0799231B1 Spiroketal derivatives, compositions containing them and their use as therapeutic agents
03/17/1999EP0626962B1 Substituted phenylheterocyclic herbicides
03/17/1999CN1211250A Photochemic spiroxazines with asymmetric monocyclic substituent, compositions and articles containing them
03/16/1999US5882544 Drugs, paints, coatings, polyurethanes plastics
03/11/1999WO1999011647A1 Fused thiophene compounds and medicinal use thereof
03/11/1999WO1999011645A1 Poly(adp-ribose) polymerase ('parp') inhibitors, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
03/11/1999WO1999011635A1 5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones useful as hiv reverse transcriptase inhibitors
03/11/1999WO1999011628A1 Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
03/11/1999WO1999011624A1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
03/11/1999CA2303295A1 5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones useful as hiv reverse transcriptase inhibitors
03/11/1999CA2302409A1 Condensed thiophene compounds and pharmaceutical use thereof
03/11/1999CA2294133A1 Poly(adp-ribose) polymerase ("parp") inhibitors, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
03/11/1999CA2294118A1 Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
03/11/1999CA2294110A1 Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
03/10/1999CN1210538A Condensed 2,3-benzodiazepine derivatives and their use as ampa-receptor inhibitors
03/09/1999US5880282 Dyes cotton in blue shades with excellent fastness properties and good fixing yield
03/09/1999US5880280 Aryl, alkyl, alkenyl and alkynylmacrolides having immunosuppressive activity
03/04/1999WO1999010342A1 Antibiotic oxazolidinone derivatives
03/04/1999WO1999009991A1 Novel amide derivatives
03/04/1999WO1998054211A3 Cyclodepsipeptides and pharmaceutical compositions containing them
03/04/1999CA2301566A1 N-acylated lipophilic amino acid derivatives
03/03/1999EP0745080B1 Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
03/03/1999EP0724570B1 Amidino derivatives useful as nitric oxide synthase inhibitors
03/02/1999US5877313 Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP