| Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960) |
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| 03/02/1999 | US5877184 Macrolides having immunosuppressive activity |
| 02/25/1999 | WO1999009017A1 Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use |
| 02/25/1999 | WO1999008668A2 Combination of tyrosine kinase inhibitor and chemical castration to treat prostate cancer |
| 02/25/1999 | CA2301227A1 Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use |
| 02/24/1999 | EP0897912A1 Amidino derivatives useful as nitric oxide synthase inhibitors |
| 02/23/1999 | US5874473 Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors |
| 02/23/1999 | US5874382 Cyclic sulfonamide herbicides |
| 02/18/1999 | WO1999007379A1 5,6-HETEROARYL-DIPYRIDO[2,3-b:3',2'-f]AZEPINES AND THEIR USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION |
| 02/18/1999 | CA2295620A1 5,6-heteroaryl-dipyrido¬2,3-b:3',2'-f|azepines and their use in the prevention or treatment of hiv infection |
| 02/17/1999 | CN1208416A Isooxacephem derivatives |
| 02/17/1999 | CN1042132C 8-amino-10-(azabicycloalkyl)-pyrido (1,2,3-D,E) (1,3,4) benzoxadiazine derivatives |
| 02/16/1999 | US5872134 Antiarrthmia, stroke, central nervous systems, schizophrenia |
| 02/16/1999 | US5871753 A compound comprising two or more multimerized ligands each independently selected from the group consisting of fk506, fk520 and cyclosporin, or macrocyclic derivatives thereof. |
| 02/11/1999 | WO1999006410A1 Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors |
| 02/11/1999 | WO1999006403A1 Tricyclic vasopressin agonists |
| 02/11/1999 | WO1999006402A1 N-acylamino acid amide compounds and intermediates for preparation thereof |
| 02/11/1999 | WO1999006374A1 Condensed pyrazole compounds |
| 02/11/1999 | CA2297988A1 Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors |
| 02/11/1999 | CA2297815A1 N-acylamino acid amide compounds and intermediates for preparation thereof |
| 02/11/1999 | CA2297407A1 Tricyclic vasopressin agonists |
| 02/11/1999 | CA2297096A1 Condensed heterocyclic compounds |
| 02/10/1999 | CN1207740A Novel intermediates and their use to prepare N,N'-bridged bisindolylmaleimides |
| 02/10/1999 | CN1207738A Substd. aminocycloalkylpyrrolidine derivs. |
| 02/09/1999 | US5869659 Microbiocides |
| 02/09/1999 | US5869655 Diamine compounds, methods of making same, method of use of same and intermediates |
| 02/09/1999 | US5869650 Potentiate cytotoxicity of anticancer drugs |
| 02/09/1999 | US5869491 Pesticides |
| 02/09/1999 | US5869483 Tricyclic benzazepine vasopressin antagonists |
| 02/09/1999 | US5869482 Dipyridio 2,3-b:3',2'-! azepines and their use in the prevention or treatment of HIV infection |
| 02/09/1999 | US5869337 Regulated transcription of targeted genes and other biological events |
| 02/03/1999 | EP0894796A1 Imidazolines substituted with a heterocyclic ring as alpha-2 antagonists |
| 02/03/1999 | EP0894003A1 N-formyl hydroxylamine containing compounds useful as ace inhibitors and/or nep inhibitors |
| 02/03/1999 | EP0893996A1 Use of rapamycin derivatives in vasculopathies and xenotransplantation |
| 02/03/1999 | EP0862553A4 Cbi analogs of cc-1065 and the duocarmycins |
| 02/03/1999 | CN1206712A Heterocyclic compound, preparation process thereof and medicinal composition containing same |
| 02/03/1999 | CN1041934C Process for preparing and/or purifying bar acid or medicinal salt or ester thereof |
| 02/03/1999 | CN1041933C Diamine salts of clavulanic acid and their preparation process and use |
| 01/30/1999 | CA2244435A1 New heterocyclic compounds, their preparation process and the pharmaceutical compounds containing them |
| 01/28/1999 | WO1999003860A1 Water soluble polymer-tacrolimus conjugated compounds and process for preparing the same |
| 01/27/1999 | EP0892804A1 Isoxazolidine derivatives |
| 01/27/1999 | EP0892780A1 M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS |
| 01/27/1999 | CN1206417A 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
| 01/21/1999 | WO1999002514A2 Epothilone derivatives |
| 01/21/1999 | WO1999002505A1 Il-5 inhibiting 6-azauracil derivatives |
| 01/21/1999 | WO1999002130A2 Storage-stable ophthalmic compositions comprising diclofenac and ofloxacin |
| 01/21/1999 | CA2294145A1 Il-5 inhibiting 6-azauracil derivatives |
| 01/20/1999 | EP0891365A1 Benzoxazines for enhancing synaptic response |
| 01/20/1999 | EP0891364A1 Calixpyrroles, calixpyridinopyrroles and calixpyridines |
| 01/20/1999 | EP0891332A1 6-phenylpyridyl-2-amine derivatives |
| 01/20/1999 | EP0707579B1 Piperidinyl substituted methanoanthracenes as d1/d2-antagonists and 5ht2-serotanin-antagonists |
| 01/20/1999 | CN1041731C Pyrido [1,2,3-d,3)(1,3,4) benzoxadiazine derivatives |
| 01/19/1999 | US5861428 Alleviation of osteoarthritis, rheumatoid arthritis, septic arthritis, periodontal disease, corneal ulceration, proteinuria, aneurysmal aortic disease, dystrophobic epidermolysis bullosa, inflammation, osteopenias, tempero |
| 01/19/1999 | US5861427 Substituted 4-biarylbutyric acid derivatives as matrix metalloprotease inhibitors |
| 01/19/1999 | US5861418 Aminobenzoic acid derivatives |
| 01/19/1999 | CA2119002C Asymmetric epoxidation reaction |
| 01/14/1999 | WO1999001458A1 Crystalline macrolides and process for their preparation |
| 01/14/1999 | WO1999001457A1 Photochromatic compounds, process for their preparation and their use in polymeric materials |
| 01/14/1999 | DE19729879A1 Lagerstabile ophthalmische Zusammensetzungen, umfassend Diclofenac und Ofloxacin A storage stable ophthalmic compositions comprising diclofenac and ofloxacin |
| 01/13/1999 | CN1205010A Isoxazolidine derivatives |
| 01/12/1999 | US5859242 Process for producing dioxazine compounds, colored materials therewith and dioxazine compounds having a plate-like crystal form |
| 01/12/1999 | US5859238 Reacting crude clavulanic acid extract in organic solvent with alkylenediamine to form diammonium salt, isolating, reacting with potassium 2-ethylhexanaote in isopropanol to form potassium clavulanate |
| 01/12/1999 | US5859047 Antiarthritic agents, nervous system disorders |
| 01/12/1999 | US5859007 Treatment of diabetes, obesity |
| 01/07/1999 | EP0889046A1 Triphendioxazines and their use as pigments |
| 01/07/1999 | EP0888359A1 Pyrimidin-4-one derivatives as pesticide |
| 01/07/1999 | EP0888356A1 Condensed 2,3-benzodiazepine derivatives and their use as ampa-receptor inhibitors |
| 01/07/1999 | EP0888352A1 Fused imidazole derivatives as multidrug resistance modulators |
| 01/07/1999 | EP0888344A1 Spirocycle integrin inhibitors |
| 01/05/1999 | US5856564 Condensed benzazepine derivative and pharmaceutical composition thereof |
| 01/05/1999 | US5856485 Resolution of an enantiomorph mixture |
| 01/05/1999 | US5856478 Anellated (oxa)hydantoins and their use as herbicides |
| 01/05/1999 | US5856324 Use of dioxomorpholines for combat endoparasites, dioxomorpholines and process for their production |
| 01/05/1999 | CA2115381C Rifaximin and pharmaceutical compositions containing it in the treatment of gastric dyspepsia caused by helicobacter pylori |
| 12/30/1998 | WO1998058947A1 Dipeptide derivatives as growth hormone secretagogues |
| 12/30/1998 | CN1203234A Tricyclic pyrazol derivatives |
| 12/29/1998 | US5854280 Antifungal sordaridin derivatives |
| 12/29/1998 | US5854277 Thiophenebutanoic acid derivatives as matrix metalloprotease inhibitors |
| 12/29/1998 | US5854274 Tricyclic heterocyclic sulfonamide and sulfonic ester derivatives |
| 12/29/1998 | US5854256 Quinuclidine derivatives |
| 12/29/1998 | US5854242 Benzoxazine antimicrobial agents |
| 12/29/1998 | US5854241 Pyrido 3,2,1-I,J! 3,1!benzoxazine derivatives |
| 12/29/1998 | US5854236 Tricyclic benzazepine vasopressin antagonists |
| 12/29/1998 | US5854234 Amidino dervatives useful as nitric oxide synthase inhibitors |
| 12/23/1998 | WO1998057951A1 NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS |
| 12/23/1998 | EP0885883A1 Fused heterocyclic compounds and pharmaceutical applications thereof |
| 12/23/1998 | EP0850427A4 Photochromic spiroxazines, compositions and articles containing them |
| 12/23/1998 | CN1202893A Novel isoxazoline and isoxazole fibrinogen deceptor antagonists |
| 12/23/1998 | CN1202825A Protein kinase C inhibitor |
| 12/23/1998 | CA2291442A1 Novel guanidine mimics as factor xa inhibitors |
| 12/22/1998 | US5852029 Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity |
| 12/22/1998 | US5852014 Condensed indole derivatives as 5HT4 -receptor antagonists |
| 12/22/1998 | US5852012 Oxadiazine derivatives |
| 12/22/1998 | US5851999 FLK-1 is a receptor for vascular endothelial growth factor |
| 12/22/1998 | CA2001201C Antimicrobial quinolonyl lactams esters |
| 12/17/1998 | WO1998056768A1 Tricyclic pyrrole or pyrazole derivatives |
| 12/17/1998 | WO1998056376A1 Novel heteroaryl compounds for the modulation of protein tyrosine enzyme related cellular signal transduction |
| 12/17/1998 | CA2293400A1 Novel heteroaryl compounds for the modulation of protein tyrosine enzyme related cellular signal transduction |
| 12/17/1998 | CA2291651A1 Tricyclic pyrrole or pyrazole derivative |
| 12/16/1998 | EP0884319A2 [1,3]oxazino[3,2-A]indole derivative |
| 12/16/1998 | EP0883403A1 Method for treating sexual dysfunctions |