| Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960) |
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| 04/22/2003 | US6552052 Pyrrolo[2,1-c][1,2,4] thiadiazoles and Pyrollo[2,1-c][1,12,4]oxadiazoles useful as nitric oxide synthase inhibitors |
| 04/22/2003 | US6552049 Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans |
| 04/22/2003 | US6552018 As antitumor agents |
| 04/22/2003 | US6552017 Substituted heterocycle fused gamma-carbolines |
| 04/17/2003 | WO2003031443A1 Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| 04/17/2003 | WO2003031441A1 Multiple action compounds |
| 04/17/2003 | WO2002094325A3 Cytotoxic cd44 antibody immunoconjugates |
| 04/17/2003 | WO2002022622A3 Synthesis of 2-hydroxymethylglutamic acid and congeners thereof |
| 04/17/2003 | US20030073697 Schizophrenia, bipolar disorders, Parkinson's disease; drug abruse |
| 04/17/2003 | US20030073687 Alzheimer's disease; anticancer agents; antidiabetic agents |
| 04/17/2003 | US20030073682 Novel substituted aryl hydroxamic acids as metalloproteinase inhibitors |
| 04/17/2003 | US20030073156 Enzymatically converting a 3-thiolated cephalosporin C compound to form a 3-thiolated -glutaryl-7-amino cephalosporanic acid compound; enzymatically converting to form 3-thiolated-7-amino cephalosporanic acid compound |
| 04/17/2003 | US20030072763 Absorb in the low- energy, ultraviolet, visible, or near-infrared (NIR) region of the electromagnetic spectrum that are used for the phototherapy of tumors and other lesions |
| 04/16/2003 | EP1302458A1 Ester derivatives |
| 04/16/2003 | EP1301518A1 Tricyclic compounds as mrp1-inhibitors |
| 04/16/2003 | EP1301495A2 Inhibitors of copper-containing amine oxidases |
| 04/16/2003 | EP0977565B1 Pharmaceutical composition comprising a tricyclic compound with enhanced stability, absorbability and low irritation potential |
| 04/16/2003 | EP0922045B1 Bicyclic pyrimidine derivatives and their use as anti-coagulants |
| 04/16/2003 | CN1411460A Substituted homopiperidinyl benzimidazole analogues as fundic relaxants |
| 04/15/2003 | US6548530 Antitumor drugs incorporate the 1,2,9,9a-tetrahydrocyclopropa(c)benz(e)indol-4-one (CBI) alkylation subunit; cytotoxic activity |
| 04/15/2003 | US6548524 Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors |
| 04/15/2003 | US6548500 Treating a cell adhesion-mediated diseases such as multiple sclerosis, asthma, atherosclerosis, rheumatoid arthritis, meningitis, comprising administering to a warm blooded animal a nitrogen atoms containing bicyclic compound |
| 04/15/2003 | US6548493 Substituted heterocycle fused gamma-carbolines |
| 04/10/2003 | WO2003028705A1 Pharmaceutical compositions comprising colloidal silicon dioxide |
| 04/10/2003 | WO2003028665A2 Methods for the purification of levofloxacin |
| 04/10/2003 | WO2003028664A2 Preparation of levofloxacin and forms thereof |
| 04/10/2003 | WO2002102793A3 Quinazolinediones as antibacterial agents |
| 04/10/2003 | US20030069430 Substituted oxindole derivatives as protein tyrosine and as protein serine/threonine kinase inhibitors and compositions and methods of treating chemotherapy and radiation therapy side effects |
| 04/10/2003 | CA2462023A1 Preparation of levofloxacin and forms thereof |
| 04/09/2003 | EP1299398A1 Methods and kits for the detection of arginine compounds |
| 04/09/2003 | EP1299395A1 Oxazinoquinolones useful for the treatment of viral infections |
| 04/09/2003 | EP1299387A1 Heterocycle carboxamides as antiviral agents |
| 04/09/2003 | EP1299378A1 Tetrahydropyridino or piperidino heterocyclic derivatives |
| 04/09/2003 | EP0902684B1 Hexahydro-pyrido(4,3-b)indole derivatives as antipsychotic drugs |
| 04/09/2003 | CN1409702A Methods for asymmetrically synthesizing enantiomer of casodex, its derivatives and intermediate thereof |
| 04/09/2003 | CN1105174C Color-safe bleach boosters, compositions and laundry methods employing same |
| 04/08/2003 | USRE38073 Biosynthesis; using dehydration agent |
| 04/08/2003 | US6544979 Fused imidazole derivatives for improving oral bioavailability of pharmaceutical agents |
| 04/08/2003 | CA2112165C Bicyclic amine derivatives |
| 04/03/2003 | WO2003027080A1 3-substituted-4-pyrimidone derivatives |
| 04/03/2003 | WO2002102313A3 Pyrimidine inhibitors of phosphodiesterase (pde) 7 |
| 04/03/2003 | US20030065180 Anticancer agents; kidney disease |
| 04/03/2003 | US20030065179 Diabetic therapy |
| 04/03/2003 | US20030065012 Estrogen receptor modulators |
| 04/03/2003 | US20030065006 Viricides; anticancer agents |
| 04/03/2003 | US20030064982 Pyrazole compounds useful as protein kinase inhibitors |
| 04/03/2003 | US20030064981 Anticancer agents; antidiabetic agents; Alzheimer's disease |
| 04/03/2003 | US20030064979 Antiproliferative agent; antidiabetic agents |
| 04/03/2003 | US20030064968 Viricides, anticarcinogneic agents |
| 04/02/2003 | EP1296987A1 Compounds for treating impaired fundic relaxation |
| 04/02/2003 | EP1296985A2 Heteropolycyclic inhibitors |
| 04/02/2003 | EP0621865B1 Rapamycin derivative and its medicinal use |
| 04/02/2003 | CN1104435C Process for the preparation of N-[(l-nButyl-4-piperidyl) methyl-3, 4-dihydro-2h-[1,3] oxazino [3,2-2] indole-10-carboxamide and salts and intermediates in the process |
| 04/02/2003 | CN1104429C 4-(3-heterocycly-1-benzoyl) pyrazoles and their use as herbicides |
| 04/01/2003 | US6541612 Complex of rapamycin-42 ester with dicarboxylic acid and fluorescein; antibody detection/generation; immunoglobulins; hybridomas; ring opening; precipitation |
| 04/01/2003 | US6541503 Substituted oxindole derivatives as protein tyrosine kinase and as protein serine/threonine kinase inhibitors |
| 04/01/2003 | US6541481 Substituted bicyclic derivatives useful as anticancer agents |
| 04/01/2003 | US6541470 Have a potent antiviral activity against picornaviruses and rotaviruses. |
| 04/01/2003 | US6541469 CRF receptor antagonists and methods relating thereto |
| 04/01/2003 | US6541451 Bactericides; microorganisms |
| 03/27/2003 | WO2003025017A1 Cytokine receptor |
| 03/27/2003 | WO2003024976A2 Tricyclic indole derivatives as 5-ht ligands |
| 03/27/2003 | WO2003024941A1 Naphthalene compounds and use thereof as drugs |
| 03/27/2003 | WO2003024448A2 Inhibitors of histone deacetylase |
| 03/27/2003 | WO2002060879A3 Bacterial gyrase inhibitors and uses thereof |
| 03/27/2003 | US20030060624 Reacting 2-chloro-4- trifluoromethyl-phenyl)-acetonitrile in the presence of a palladium catalyst and a base to form indene derivative |
| 03/27/2003 | CA2465978A1 Inhibitors of histone deacetylase |
| 03/27/2003 | CA2460151A1 Cytokine receptor |
| 03/27/2003 | CA2460126A1 Tricyclic indole derivatives as 5-ht ligands |
| 03/26/2003 | EP1294698A1 Fused azepine derivatives and their use as antidiuretic agents |
| 03/26/2003 | CN1406230A 2,4-di (hetero-) arylamino (-oxy)-5-substituted pyrimidines as antineoplastic agents |
| 03/26/2003 | CN1406227A Aryl fused azapolycy clic compounds |
| 03/26/2003 | CN1406225A Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists |
| 03/26/2003 | CN1406182A Benzbisazole compound and optical recording medium containing the compound |
| 03/26/2003 | CN1103769C Tricyclic amine derivatives |
| 03/25/2003 | US6538004 Potassium channel modulators relax smooth muscle cells and inhibit bladder contractions; treating nervous, eating, cardiovascular, gastrointestinal, and sexual disorders |
| 03/25/2003 | US6537964 The present invention describes the use of fumitremorgin A, B and C and a series of diketopiperazines of Formula (I) to resensitize multidrug resistant (MDR) cancer cells to the cytotoxic effects of chemotherapeutic drugs. |
| 03/25/2003 | CA2237221C Protein kinase c inhibitor |
| 03/20/2003 | WO2003022807A2 Medical devices containing rapamycin analogs |
| 03/20/2003 | WO2003022806A2 Cbi analogues of cc-1065 and the duocarmycins |
| 03/20/2003 | WO2003022433A2 A derivatized macrocycle compound for covalent bonding to a substrate and method of forming and use |
| 03/20/2003 | WO2003022324A1 Medical devices containing rapamycin analogs |
| 03/20/2003 | WO2003022214A2 Piperazine and homopiperazine compounds |
| 03/20/2003 | WO2002102808A3 (PYRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES AS POSITIVE MODULATORS OF THE AMPA RECEPTOR |
| 03/20/2003 | US20030055286 Il-8 receptor antagonists |
| 03/20/2003 | US20030055226 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| 03/20/2003 | US20030055068 Pyrazole compounds useful as protein kinase inhibitors |
| 03/20/2003 | US20030055050 CRF receptor antagonists and methods relating thereto |
| 03/20/2003 | US20030055044 Administering pyrazole derivative for inhibiting GSK-3 or Aurora activity in a patient |
| 03/20/2003 | CA2460074A1 Medical devices containing rapamycin analogs |
| 03/20/2003 | CA2459308A1 Cbi analogues of cc-1065 and the duocarmycins |
| 03/19/2003 | EP1292573A2 Substituted thioacetamides |
| 03/19/2003 | EP1292302A2 Method of treating cardiovascular disease using rapamycin |
| 03/19/2003 | EP1292299A2 New use of citreamicins |
| 03/19/2003 | EP1149106B1 4,5-azolo-oxindoles |
| 03/18/2003 | US6534516 Method of affecting androgen receptor activity comprising the in vivo administration of a composition |
| 03/18/2003 | US6534510 Anticoagulants |
| 03/18/2003 | US6534506 Inhibitors of prenyl-protein transferase |
| 03/18/2003 | US6534491 Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors |
| 03/18/2003 | CA2200607C Processes and intermediates for preparing 5,7-dihydro-3-[2-{1-benzylpiperidin-4-yl}ethyl]-6h-pyrrolo-[4,5-f]-1,2-benzisoxazol-6-one |