Patents
Patents for C07D 491 - Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or (29,726)
11/2008
11/13/2008US20080281103 Azaspiro derivatives
11/13/2008US20080280935 Process to Prepare Camptothecin Derivatives
11/13/2008US20080280892 Tricyclic nitrogen antibacterial; 1-({4-[(2,3-Dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)amino]-1-piperidinyl}methyl)-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one; may be used with other active ingredients, diluents
11/13/2008US20080280876 Sphingosine-1-phosphate (S1P) receptor agonists or antagonists; immunosuppressants; e.g. 3-(3-chloro-4-isopropoxyphenyl)-5-(p-(3-carboxyazetidin-1-ylmethyl)phenyl)-1,2,4-oxadiazole; two specific compounds are excluded
11/13/2008US20080280869 Therapy for diseases resulting from mutation of messenger Rna; suppression prenature translation termination; autoimmune diseases; blood disorders; collagen disease; diabetes; neurodegenerative diseases; cardiovascular disorders; central nervous system disorders; antiinflammatory agents
11/13/2008US20080280855 Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
11/13/2008CA2674831A1 5,6-ring annulated indole derivatives and methods of use thereof
11/12/2008EP1989204A1 Pyrazoloquinolones are potent parp inhibitors
11/12/2008EP1511732B9 Process for the manufacture of quinoline derivatives
11/12/2008CN101305010A Raf inhibitor compounds and methods of use thereof
11/12/2008CN101305009A Aza-substituted spiro derivative
11/12/2008CN101304997A Bridged N-bicyclic sulfonamido inhibitors of gamma secretase
11/12/2008CN101302220A N-benzoyl rhodamine B hydrazine, preparation and use thereof
11/12/2008CN101302182A Virus polymerase inhibitors
11/12/2008CN100432076C Camptothecine derivative, preparing method and use
11/12/2008CN100432067C Dibenzanthracene, dinaphthopyran and dibenzanthracene, dinaphtho spiropyran analog compound and its preparation
11/12/2008CN100432055C Tricyclic protein kinase inhibitors
11/11/2008US7449579 Detection of electrophilic and nucleophilic chemical agents
11/11/2008US7449479 Hepatitis C virus inhibitors
11/11/2008US7449475 e.g. 2-{[(2S)-3-(5-Chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-N-cyclopropylbenzamide; macrophage inflammatory protein (MIP)-1 alpha chemokine receptor modulator; antiinflammatory, antiproliferative agent, autoimmune diseases
11/11/2008US7449472 Methods of inhibiting p38 with substituted bicyclic pyrimidines
11/11/2008US7449465 glycogen synthase kinase 3 alpha and 3 beta inhibitors; improved phanrmacological activity, potency, selectivity, solubility, permeability, metabolic stability; bipolar disorder; Alzheimer's disease; type II diabetes, neuropathic pain; depression; inflammatory diseases
11/11/2008US7449464 4-{3-[4-(6-Chlorobenzothiazol-2-yl)-1,4-diazepan-1-ylcarbonyl]benzyl}-1(2H)-phthalazinone; Cancer, BRCA deficient
11/06/2008WO2008133288A1 Tricyclic aryl compounds
11/06/2008WO2008132679A1 Bridged six-membered ring compounds
11/06/2008US20080275090 P2Y1 Purinoreceptor; thromboembolic disorders; compounds are 2-((hetero)arylamino) benzimidazoles, benzoxazoles or benzothiazoles such as [2-(2-tert-butyl-phenoxy)-pyridin-3-yl]-(6-methyl-1H-benzoimidazol-2-yl)-amine
11/06/2008US20080274893 Spirocyclic 3-Phenyl-3substituted-4-Ketolactams and-lactones
11/06/2008CA2683866A1 Bridged six-membered ring compounds
11/05/2008EP1987829A1 Prophylactic or therapeutic agent for cerebral ischemia or cerebral ischemic reperfusion injury in stroke
11/05/2008EP1987020A1 Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
11/05/2008EP1986647A2 4-acylaminopyridine derivative mediated neurogenesis
11/05/2008EP1986646A1 Novel azacycly-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
11/05/2008EP1761515B1 2-(hetero-)aryl substituted tetrahydroquinoline derivatives
11/05/2008EP1732921B1 Thioamide derivatives as progesterone receptor modulators
11/05/2008CN100430402C Method of refining plamatine from herba fibranreae recisae total ulkuloid and its application
11/05/2008CN100430401C 4-phenyl substd. tetrahydroisoquinolines and therapeutic use thereof
11/05/2008CN100430400C Cyclic-aliphatic epoxy compound containing pheneylethylene cinnamyl or maleimide functional group
11/05/2008CN100430396C 2-phenyl-substituted imidazo-triazone used as phosphodiesterase inhibitor
11/04/2008US7446199 Compositions useful as inhibitors of protein kinases
11/04/2008US7446122 Substituted indole derivatives
11/04/2008US7446113 the prodrug forms of compounds have good absorption, pharmacokinetics, distribution and transport to the brain; 4-[8-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylethynyl]-benzenesulfonamide; nervous system disorders like psychosis, schizophrenia, Alzheimer's disease, depression
11/04/2008US7446104 Histamine receptor antagonists; 4-[3-(4-Piperidin-1-yl-but-1-ynyl)-benzyl]-thiomorpholine; antiallergens, antihistamines, antiepileptic agents; asthma, alzheimer's disease, narcolepsy, motion sickness, attention deficit disorder, schizophrenia
11/04/2008US7446103 N-[4-(3-Piperidin-1-ylpropoxy)-benzoyl]-5-fluoroisoindoline; Alzheimer's disease; cognition enhancers; amidation
11/04/2008CA2310458C Piperidine derivatives
10/2008
10/30/2008WO2008131119A2 Composition and method for cancer treatment and prevention
10/30/2008WO2008130534A1 Crystalline forms of topotecan hydrochloride and processes for making the same
10/30/2008WO2008128961A1 Compounds
10/30/2008WO2008085942A3 Methods for preparing arene-bis(dicarboximide)-based semiconducting materials and related intermediates for preparing same
10/30/2008WO2008016648A3 Certain chemical entities, compositions and methods
10/30/2008US20080269493 Crystalline forms of topotecan hydrochloride and processes for making the same
10/30/2008US20080269487 6-{[1-(carbamoylmethyl)piperidin-4-yl]oxy}-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline; prevent, treat tumours which are sensitive to inhibition of erbB receptor tyrosine kinases
10/30/2008US20080269482 Use of Rylene Derivatives as Photosensitizers in Solar Cells
10/30/2008US20080269298 anticarcinogenic agent, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide; for treatment of susceptible neoplasm selected from breast, colon, lung, prostate cancer, lymphoma, leukemia, endometrial cancer, melanoma, ovarian, pancreatic, head and neck
10/30/2008US20080269253 Pain therapy; headaches; neurodegenerative diseases; stroke; skin disorders; antiischemic agents; Huntington's disease; antiulcer agents; inflammatory bowel disorders;amyotropic lateral sclerosis
10/30/2008US20080269245 Histone deacetylase inhibitors; anticancer agents; antiprotozoa agents
10/30/2008US20080269239 Antiinflammatory agents; asthma;antiarthritic agents; psoriasis; inflammatory bowel disorders; rhinitis; dermatitis; antiallergens
10/30/2008US20080269227 Autoimmune diseases; antiinflamamtory agents, cardiovascular disorders; neurodegenerative diseases, kidney diseases, anticancer agents; platelet aggregation
10/30/2008US20080269169 silyl camptothecin derivatives for cancer and/or leukemia; cytotoxic; DNA-topoisomerase I inhibitors; antitumor agents; 7-trimethylsilyl-10-acetoxy camptothecin, 7-trimethylsilyl-11-fluoro camptothecin
10/30/2008CA2684599A1 Crystalline forms of topotecan hydrochloride and processes for making the same
10/29/2008EP1985294A1 Agent for improvement of hepatic function
10/29/2008EP1984375A2 Chemical compounds
10/29/2008EP1951235A4 Novel crystal forms of irinotecan hydrochloride
10/29/2008EP1749011B1 Bicyclic heterocycles as hiv integrase inhibitors
10/29/2008EP1531811B1 Derivatives of 3-hydroxy-4-(cyclyl-alkylaminoalkyl)-5-phenyl-1h-pyrazole as antagonists of the gonadotropin releasing hormone (gnrh) for use in the treatment of sex hormone related conditions, such as prostatic of uterine cancer
10/28/2008US7442809 Method for producing 1,3-dioxolan-4,6-dione compound
10/28/2008US7442804 heating under microwave irradiation (3-hydroxymethylene-4-carboxylic acid ester-2-one)pyrroline derivatives in presence of inert solvent to produce 3,6-diphenylfuro[3,4-c]pyrrole-1,4-diones (furopyrroles); intermediates in process for preparation of diketopyrrolopyrroles; high yield and purity
10/28/2008US7442710 Substituted phenyl methanones
10/28/2008US7442709 c-Kit proto-oncogene inhibitors(KIT, CD-117, stem cell or mast cell growth factor receptor); anticancer; better selectivity, potency, reduced toxicity, side effects; leukemias; angiogenesis; 3-{3-[(4-(Trifluoromethoxy)benzyl)oxy]phenyl}-N-(pyridine-3-ylmethyl)-3H-imidazo[4,5-b]pyridine-6-carboxamide
10/28/2008CA2417652C Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
10/28/2008CA2403152C Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
10/23/2008WO2008127606A1 Process for making topotecan
10/23/2008WO2008127585A1 Substituted furo[2,3-b]pyridine derivatives as cannabinoid-1 receptor modulators
10/23/2008WO2008126901A1 Nitrogen-containing heterocyclic compound and pharmaceutical composition containing the same
10/23/2008WO2008126898A1 (aza)indole derivative and use thereof for medical purposes
10/23/2008WO2008125421A1 Trans-annular rearrangement of active lactames
10/23/2008WO2008125349A1 Spiro-pyrano-pyrazole derivatives
10/23/2008WO2008125348A1 Pyrano-pyrazole-amines
10/23/2008WO2008081282A3 Process for the synthesis of n9-(3,5-dichloro-4-pyridyl)-6- difluoromethoxybenzo(4,5)furo(3,2-c)pyridine-9-carboxamide and salts thereof
10/23/2008US20080262232 Crystal structure antibiotic; drugs for oral or topical use; heating, dissolving in ethanol; drying; process control
10/23/2008US20080262224 Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide
10/23/2008US20080262024 Rifaximin compositions and method of use
10/23/2008US20080262016 Isoquinoline derivatives and methods of use thereof
10/23/2008US20080262013 Oxymorphone controlled release formulations
10/23/2008US20080261963 antibiotics, fungicides, viricides; treating microbial infections; fused rings based on 4-oxo-4H-pyrido[3,2,1-kl]benzo[g]-phenoxazine for example; Tumor suppression agents with reduced side effects; anticancer
10/23/2008US20080261946 Pyrimidine Compounds for the Treatment of Inflammatory Disorders
10/23/2008US20080261272 reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered; antifungal agents; inhibiting expression of cell wall glycoproteins and preventing pathogens from showing pathogenicity; DNA
10/23/2008US20080260685 Prodrugs of cc-1065 analogs
10/23/2008CA2683586A1 Substituted furo[2,3-beta]pyridine derivatives as cannabinoid 1-receptor modulators
10/23/2008CA2682391A1 (aza)indole derivative and use thereof for medical purposes
10/23/2008CA2681327A1 Trans-annular rearrangement of active lactames
10/23/2008CA2678433A1 Pyrano-pyrazole-amines
10/23/2008CA2678134A1 Spiro-pyrano-pyrazole derivatives
10/22/2008EP1982987A1 Spiro-pyrano-pyrazole derivatives
10/22/2008EP1982982A1 Novel coumarin derivative having antitumor activity
10/22/2008EP1982714A1 Pyrano-pyrazole-amines
10/22/2008EP1981342A1 Selective benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors
10/22/2008EP1677599A4 Hydroxy pyridopyrrolopyrazine dione compounds useful as hiv integrase inhibitors
10/22/2008CN101289452A Process for abstracting camptothecine form nothapodytes
10/22/2008CN101289451A Pentacyclic fused heterocycle compounds with chinoline backbone and method for preparing same
10/22/2008CN101289442A Novel benzoimidazole derivatives useful as antiproliferative agents
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